METHODS AND MATERIALS FOR THE DETECTION OF MELAMINE
    29.
    发明申请
    METHODS AND MATERIALS FOR THE DETECTION OF MELAMINE 有权
    检测梅毒的方法和材料

    公开(公告)号:US20150004713A1

    公开(公告)日:2015-01-01

    申请号:US14296034

    申请日:2014-06-04

    Abstract: Methods and materials for the detection of melamine in test samples such as foodstuffs are described. Embodiments of the invention comprise combining a test sample suspected of containing melamine with a particle that produces a colorimetric and/or turbidimetric signal that is dependent upon the concentration of melamine in the test sample. In certain embodiments of the invention, the particles and test sample are combined together with a chemical compound selected to induce the aggregation melamine in a manner that amplifies the colorimetric and/or turbidimetric signal of the assay. In some embodiments of the invention, the aggregation inducing agent is not physically coupled to the particles used in the assays. In other embodiments of the invention, the aggregation inducing agent is physically coupled to the particles used in these assays.

    Abstract translation: 描述了测试样品如食品中检测三聚氰胺的方法和材料。 本发明的实施方案包括将怀疑含有三聚氰胺的测试样品与产生取决于测试样品中三聚氰胺浓度的比色和/或比浊信号的颗粒组合。 在本发明的某些实施方案中,颗粒和测试样品与选择用于以扩增测定的比色和/或比浊信号的方式诱导聚集三聚氰胺的化学化合物组合在一起。 在本发明的一些实施方案中,聚集诱导剂不与用于测定中的颗粒物理偶联。 在本发明的其它实施方案中,聚集诱导剂与这些测定中使用的颗粒物理耦合。

    Conjugated polymers for use in homogeneous and solid state assays
    30.
    发明授权
    Conjugated polymers for use in homogeneous and solid state assays 有权
    用于均相和固态测定的共轭聚合物

    公开(公告)号:US08759444B2

    公开(公告)日:2014-06-24

    申请号:US13726520

    申请日:2012-12-24

    Abstract: Disclosed are multichromophores, and methods, articles and compositions employing them. Disclosed are methods, articles and compositions for the detection and analysis of biomolecules in a sample. Provided assays include those determining the presence of a target biomolecule in a sample or its relative amount, or the assays may be quantitative or semi-quantitative. The methods can be performed on a substrate or in an array format on a substrate. Disclosed are detection assays employing sensor biomolecules that do not comprise a fluorophore that can exchange energy with the cationic multichromophore. Disclosed are biological assays in which energy is transferred between one or more of the multichromophore, a label on the target biomolecule, a label on the sensor biomolecule, and/or a fluorescent dye specific for a polynucleotide, in all permutations.

    Abstract translation: 公开了多重色谱和其使用它们的方法,制品和组合物。 公开了用于检测和分析样品中生物分子的方法,制品和组合物。 提供的测定包括确定样品中靶生物分子的存在或其相对量的那些,或者测定可以是定量或半定量的。 该方法可以在衬底上以阵列形式在衬底上进行。 公开了使用不包含可与阳离子多重色素交换能量的荧光团的传感器生物分子的检测测定。 公开了在所有排列中能量在一个或多个多色素,目标生物分子上的标记,传感器生物分子上的标记和/或多核苷酸特异的荧光染料之间转移能量的生物测定。

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