Abstract:
Certain substituted indoles that are modulators of one or more or of CRTH2, COX-2 AND FAAH are described. The compounds are useful for treatment of pain and/or inflammation as well as other disorders.
Abstract:
A biosensor is described comprising an electrode, a protein layer (s), and a double-stranded polynucleotide layer (s). Also included do arrays, kits, and instruments comprise the biosensors. The biosensors may be used to detect double-stranded polynucleotide damage resulting from metabolism of a test compound, such as a drug candidate, by the protein in the protein layer.
Abstract:
A remote monitoring and alerting system is provided for an appliance with knobs operation, such as an electrical or gas stove or range, to reduce the hazard caused by ignorance or forgetfulness during use of the appliance. The system includes one or more electrical knobs comprising a knob position sensor, a motion sensor; an alarm unit, and micro controller with timer function. A knob position sensor installed on a knob is connected to micro controller, the knob position sensor enabled for detection of appliance operation, the apparatus of the invention signals a person with an alarm when the person has not attended to the stove for a predetermined period of time. Users can be notified and interact with the connected apparatus through wireless network using mobile devices.
Abstract:
In the field of communications technologies, a down sampling method and a down sampling device are provided, to enable the energy of a down sampling point obtained in down sampling to be as large as possible. The down sampling method includes: extracting energy statistical values of sampling point sets in a current period; selecting a sampling position corresponding to a sampling point set with the largest energy statistical value as a down sampling position; and performing down sampling according to the down sampling position.
Abstract:
A method and device for estimating a Gaussian white noise power in a channel and a receiver are provided. The method includes performing a multi-path search on a received signal to find out paths of the signal; performing a noise estimation on one of the paths to acquire a total noise power of the path; performing an inter-path interference noise estimation on N paths spaced apart from the path by an integral number of chips to obtain an inter-path interference noise power of a single path of the signal, where N is an integer greater than or equal to 1; and subtracting the inter-path interference noise power from the total noise power to obtain the Gaussian white noise power. Through the technical solution of the disclosure, the Gaussian white noise power in a channel is obtained with a higher accuracy, so that the performance of equalization is enhanced.
Abstract:
The present invention provides a security functional thin film and a security product containing such a thin film. The security functional thin film is of an amorphous structure, and possesses soft magnetic characteristics. Large Barkhausen effect can be detected along the in-plane preferred direction of magnetization; and the Large Barkhausen effect significantly attenuates, or no such signal can be detected, in a direction perpendicular to the in-plane preferred direction of magnetization. The thin film has a thickness of 20-300 nm, and the thin film also possesses element encoding characteristics that can be authenticated by experts. The security functional thin film of the present invention can be fabricated by magnetron sputtering web coating process. The security product provided by the present invention has a security information layer formed of the security functional thin film, and can be combined with other security characteristics for use in fabricating security materials such as security threads, security tapes, paper security strip-like inserts, or security labels, and others. Compared with conventional anti-counterfeiting technologies, the instant security functional thin film has more hidden security information, and facilitates enhancement of safety performance of security products.
Abstract:
Ghrelin O-acyltransferase (GOAT) is inhibited with designed small molecules. Methods comprise contacting the GOAT with an inhibitor and detecting a resultant inhibition.
Abstract:
The present invention provides a security functional thin film and a security product containing such a thin film. The security functional thin film is of an amorphous structure, and possesses soft magnetic characteristics. Large Barkhausen effect can be detected along the in-plane preferred direction of magnetization; and the Large Barkhausen effect significantly attenuates, or no such signal can be detected, in a direction perpendicular to the in-plane preferred direction of magnetization. The thin film has a thickness of 20-300 nm, and the thin film also possesses element encoding characteristics that can be authenticated by experts. The security functional thin film of the present invention can be fabricated by magnetron sputtering web coating process. The security product provided by the present invention has a security information layer formed of the security functional thin film, and can be combined with other security characteristics for use in fabricating security materials such as security threads, security tapes, paper security strip-like inserts, or security labels, and others. Compared with conventional anti-counterfeiting technologies, the instant security functional thin film has more hidden security information, and facilitates enhancement of safety performance of security products.
Abstract:
A locking and ejecting apparatus includes a carriage for holding an electronic module having a connector therein, a sliding bracket slid in the carriage, a mating connector attached to the sliding bracket for connecting with the connector, a triggering portion formed on the sliding bracket, a push-push switch attached to the carriage, and a resilient member. Two actuated retaining pieces are formed on the push-push switch, and a trigger is set between the retaining pieces. When the sliding bracket is slid relative to the carriage, the resilient member is deformed and the trigger is triggered by the triggering portion, the retaining pieces are actuated to hold the triggering portion, the sliding bracket is locked in the carriage. When the trigger is triggered again, the retaining pieces are actuated to release the triggering portion, the sliding bracket is ejected out of the carriage by a restoring force of the resilient member.