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公开(公告)号：US12065488B2
公开(公告)日：2024-08-20
申请号：US17516082
申请日：2021-11-01
Applicant: Janssen Biotech, Inc. , Applied Molecular Evolution, Inc.
Inventor： Yan Chen , Debra Gardner , David M. Knight , Michael W. Lark , Bailin Liang , David M. Marquis , David J. Shealy , Eric Michael Smith , Xiao-yu R. Song , Vedrana Stojanovic-Susulic , Raymond Sweet , Susan Tam , Alain P. Vasserot , Sheng-Jiun Wu , Jing Yang
CPC classification number: C07K16/248 , A61K2039/505 , A61K2039/54 , C07K2317/21 , C07K2317/24 , C07K2317/33 , C07K2317/34 , C07K2317/56 , C07K2317/565 , C07K2317/567 , C07K2317/73 , C07K2317/76 , C07K2317/92
Abstract: Anti-IL-6 antibodies and antirheumatics are useful to treat and suppress IL-6 related conditions, such as rheumatoid arthritis.
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公开(公告)号：US20220054634A1
公开(公告)日：2022-02-24
申请号：US17522423
申请日：2021-11-09
Applicant: Janssen Biotech, Inc.
Inventor： Jacquelne Benson , Mark Cunningham , Cynthia Duchala , Jill Giles-Komar , Jinquan Luo , Michael Rycyzyn , Raymond Sweet
IPC: A61K39/395 , G01N33/68 , C07K16/24 , A61K45/06
Abstract: An anti-IL-23 antibody, including isolated nucleic acids that encode at least one anti-IL-23 antibody, vectors, host cells, transgenic animals or plants, and methods of making and using thereof have applications in diagnostic and/or therapeutic compositions, methods and devices.
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公开(公告)号：US11180549B2
公开(公告)日：2021-11-23
申请号：US16717594
申请日：2019-12-17
Applicant: Janssen Biotech, Inc. , Applied Molecular Evolution, Inc.
Inventor： Yan Chen , Debra Gardner , David M. Knight , Michael W. Lark , Bailin Liang , David M. Marquis , David J. Shealy , Eric Michael Smith , Xiao-yu R. Song , Vedrana Stojanovic-Susulic , Raymond Sweet , Susan Tam , Alain P. Vasserot , Sheng-Jiun Wu , Jing Yang
Abstract: Anti-IL-6 antibodies and antirheumatics are useful to treat and suppress IL-6 related conditions, such as rheumatoid arthritis.
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公开(公告)号：US20200277393A1
公开(公告)日：2020-09-03
申请号：US16878209
申请日：2020-05-19
Applicant: Janssen Biotech, Inc
Inventor： John Chen , Johan Fransson , Natalie Fursov , Damon Hamel , Thomas Malia , Galina Obmolova , Tatiana Ort , Michael Rycyzyn , Michael Scully , Raymond Sweet , Alexey Teplyakov , John Wheeler , Juan Carlos Almagro
IPC: C07K16/28
Abstract: Human antibodies immunospecific for human CD27 are capable of blocking CD27 binding to its ligand CD70 and neutralizing bioactivity of CD27 including, but not limited to, CD27 intracellular signaling, T-cell proliferation and activation, B-cell proliferation and differentiation, plasmablast formation and alleviation of antibody responses, stimulation of tumor cells by CD70, and the production of soluble mediators from T and B-cells. The antibodies are useful in diagnosing or treating CD27 activity associated diseases and conditions.
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公开(公告)号：US20170290912A1
公开(公告)日：2017-10-12
申请号：US15626697
申请日：2017-06-19
Applicant: Janssen Biotech, Inc.
Inventor： Jacqueline Benson , Mark Cunningham , Cynthia Duchala , Jill Giles-Komar , Jinquan Luo , Michael Rycyzyn , Raymond Sweet
IPC: A61K39/395 , A61K45/06
CPC classification number: A61K39/3955 , A61K39/00 , A61K45/06 , A61K2039/505 , A61K2039/55527 , A61K2039/55544 , C07K16/244 , C07K2317/30 , C07K2317/33 , C07K2317/34 , C07K2317/56 , C07K2317/565 , C07K2317/76 , C07K2317/92 , C07K2319/55 , G01N33/6869 , G01N2333/54 , Y02A50/386 , Y02A50/401 , Y02A50/41 , Y02A50/412 , Y02A50/57 , Y02A50/58
Abstract: An anti-IL-23 antibody, including isolated nucleic acids that encode at least one anti-IL-23 antibody, vectors, host cells, transgenic animals or plants, and methods of making and using thereof have applications in diagnostic and/or therapeutic compositions, methods and devices.
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Patent Agency Ranking
公开(公告)号：US09683046B2
公开(公告)日：2017-06-20
申请号：US14790144
申请日：2015-07-02
Applicant: Janssen Biotech, Inc.
Inventor： John Chen , Johan Fransson , Natalie Fursov , Damon Hamel , Thomas Malia , Galina Obmolova , Tatiana Ort , Michael Rycyzyn , Michael Scully , Raymond Sweet , Alexey Teplyakov , John Wheeler , Juan Carlos Almagro
CPC classification number: C07K16/2878 , A61K2039/505 , C07K16/2896 , C07K2317/24 , C07K2317/34 , C07K2317/55 , C07K2317/565 , C07K2317/73 , C07K2317/76 , C07K2317/92
Abstract: Human antibodies immunospecific for human CD27 are capable of blocking CD27 binding to its ligand CD70 and neutralizing bioactivity of CD27 including, but not limited to, CD27 intracellular signaling, T-cell proliferation and activation, B-cell proliferation and differentiation, plasmablast formation and alleviation of antibody responses, stimulation of tumor cells by CD70, and the production of soluble mediators from T and B-cells. The antibodies are useful in diagnosing or treating CD27 activity associated diseases and conditions.
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公开(公告)号：US20170058041A1
公开(公告)日：2017-03-02
申请号：US15345860
申请日：2016-11-08
Applicant: Janssen Biotech, Inc.
Inventor： Mark Cunningham , Yiqing Feng , Katharine Heeringa , Jinquan Luo , Robert Rauchenberger , Mark Rutz , Lani San Mateo , Robert Sarisky , Raymond Sweet , Fang Teng , Alexey Teplyakov , Sheng-Jiun Wu
IPC: C07K16/28
CPC classification number: C07K16/2896 , A61K39/39533 , A61K39/3955 , A61K2039/505 , C07H21/04 , C07K14/705 , C07K16/18 , C07K16/28 , C07K16/2863 , C07K2317/21 , C07K2317/24 , C07K2317/33 , C07K2317/34 , C07K2317/51 , C07K2317/515 , C07K2317/52 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/76 , C07K2317/92 , C07K2317/94 , C12N5/10 , C12N5/12 , C12N15/117 , C12N15/63 , C12N2310/17 , A61K39/00 , A61K2300/00
Abstract: Toll Like Receptor 3 (TLR3) antibody antagonists, polynucleotides encoding TLR3 antibody antagonists or fragments thereof, and methods of making and using the foregoing are disclosed.
Abstract translation: 公开了Toll样受体3（TLR3）抗体拮抗剂，编码TLR3抗体拮抗剂或其片段的多核苷酸，以及制备和使用前述物质的方法。
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公开(公告)号：US20170044252A1
公开(公告)日：2017-02-16
申请号：US15337512
申请日：2016-10-28
Applicant: Janssen Biotech, Inc.
Inventor： Jacqueline Benson , Mark Cunningham , Cynthia Duchala , Jill Giles-Komar , Jinquan Luo , Michael Rycyzyn , Raymond Sweet
IPC: C07K16/24 , A61K45/06 , A61K39/395
CPC classification number: A61K39/3955 , A61K39/00 , A61K45/06 , A61K2039/505 , A61K2039/55527 , A61K2039/55544 , C07K16/244 , C07K2317/30 , C07K2317/33 , C07K2317/34 , C07K2317/56 , C07K2317/565 , C07K2317/76 , C07K2317/92 , C07K2319/55 , G01N33/6869 , G01N2333/54 , Y02A50/386 , Y02A50/401 , Y02A50/41 , Y02A50/412 , Y02A50/55 , Y02A50/57 , Y02A50/58
Abstract: An anti-IL-23 antibody, including isolated nucleic acids that encode at least one anti-IL-23 antibody, vectors, host cells, transgenic animals or plants, and methods of making and using thereof have applications in diagnostic and/or therapeutic compositions, methods and devices.
Abstract translation: 抗IL-23抗体，包括编码至少一种抗IL-23抗体，载体，宿主细胞，转基因动物或植物的分离的核酸及其制备和使用的方法具有诊断和/或治疗组合物中的应用 ，方法和设备。
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公开(公告)号：US09505837B2
公开(公告)日：2016-11-29
申请号：US14812375
申请日：2015-07-29
Applicant: Janssen Biotech, Inc.
Inventor： Jacqueline Benson , Mark Cunningham , Cynthia Duchala , Jill M. Giles-Komar , Jinquan Luo , Michael A. Rycyzyn , Raymond Sweet
CPC classification number: A61K39/3955 , A61K39/00 , A61K45/06 , A61K2039/505 , A61K2039/55527 , A61K2039/55544 , C07K16/244 , C07K2317/30 , C07K2317/33 , C07K2317/34 , C07K2317/56 , C07K2317/565 , C07K2317/76 , C07K2317/92 , C07K2319/55 , G01N33/6869 , G01N2333/54 , Y02A50/386 , Y02A50/401 , Y02A50/41 , Y02A50/412 , Y02A50/55 , Y02A50/57 , Y02A50/58
Abstract: An anti-IL-23 antibody, including isolated nucleic acids that encode at least one anti-IL-23 antibody, vectors, host cells, transgenic animals or plants, and methods of making and using thereof have applications in diagnostic and/or therapeutic compositions, methods and devices.
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公开(公告)号：US09481731B2
公开(公告)日：2016-11-01
申请号：US13751718
申请日：2013-01-28
Applicant: Janssen Biotech, Inc.
Inventor： Mark Cunningham , Yiqing Feng , Katharine Heeringa , Jinquan Luo , Robert Rauchenberger , Mark Rutz , Lani San Mateo , Robert Sarisky , Vedrana Stojanovic-Susulic , Raymond Sweet , Fang Teng , Alexey Teplyakov , Sheng-Jiun Wu
IPC: C07K16/18 , C07K16/28 , A61K39/00 , A61K39/395 , C07K14/435 , C07K14/705
CPC classification number: C07K16/2896 , A61K39/39533 , A61K39/3955 , A61K2039/505 , C07H21/04 , C07K14/705 , C07K16/18 , C07K16/28 , C07K16/2863 , C07K2317/21 , C07K2317/24 , C07K2317/33 , C07K2317/34 , C07K2317/51 , C07K2317/515 , C07K2317/52 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/76 , C07K2317/92 , C07K2317/94 , C12N5/10 , C12N5/12 , C12N15/117 , C12N15/63 , C12N2310/17 , A61K39/00 , A61K2300/00
Abstract: Toll Like Receptor 3 (TLR3) antibody antagonists, polynucleotides encoding TLR3 antibody antagonists or fragments thereof, and methods of making and using the foregoing are disclosed.
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