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公开(公告)号：US12129293B2
公开(公告)日：2024-10-29
申请号：US17181778
申请日：2021-02-22
Applicant: Janssen Biotech, Inc.
Inventor： Jacqueline Benson , Jill Carton , Mark Cunningham , Yevgeniya Orlovsky , Robert Rauchenberger , Raymond Sweet
CPC classification number: C07K16/244 , A61K9/0019 , A61K9/08 , A61K39/3955 , A61K47/26 , A61K2039/505 , C07K2317/21 , C07K2317/34 , C07K2317/52 , C07K2317/55 , C07K2317/565 , C07K2317/73 , C07K2317/76 , C07K2317/92 , C07K2319/00 , C07K2319/30
Abstract: A human anti-IL-23p19 antibody, including isolated nucleic acids that encode at least one anti-IL-23p19 antibody, vectors, host cells, and methods of making and using thereof have applications in diagnostic and/or therapeutic compositions, methods and devices.
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2.发明授权公开(公告)号：US10301392B2
公开(公告)日：2019-05-28
申请号：US15596609
申请日：2017-05-16
Applicant: Janssen Biotech, Inc.
Inventor： John Chen , Johan Fransson , Natalie Fursov , Damon Hamel , Thomas Malia , Galina Obmolova , Tatiana Ort , Michael Rycyzyn , Michael Scully , Raymond Sweet , Alexey Teplyakov , John Wheeler , Juan Carlos Almagro
Abstract: Human antibodies immunospecific for human CD27 are capable of blocking CD27 binding to its ligand CD70 and neutralizing bioactivity of CD27 including, but not limited to, CD27 intracellular signaling, T-cell proliferation and activation, B-cell proliferation and differentiation, plasmablast formation and alleviation of antibody responses, stimulation of tumor cells by CD70, and the production of soluble mediators from T and B-cells. The antibodies are useful in diagnosing or treating CD27 activity associated diseases and conditions.
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公开(公告)号：US09932404B2
公开(公告)日：2018-04-03
申请号：US15345860
申请日：2016-11-08
Applicant: Janssen Biotech, Inc.
Inventor： Mark Cunningham , Yiqing Feng , Katharine Heeringa , Jinquan Luo , Robert Rauchenberger , Mark Rutz , Lani San Mateo , Robert Sarisky , Raymond Sweet , Fang Teng , Alexey Teplyakov , Sheng-Jiun Wu
IPC: A61K39/395 , C07K16/28 , C07H21/04 , C12N15/117 , C07K14/705 , C12N5/10 , C12N5/12 , C12N15/63 , A61K39/00
CPC classification number: C07K16/2896 , A61K39/39533 , A61K39/3955 , A61K2039/505 , C07H21/04 , C07K14/705 , C07K16/18 , C07K16/28 , C07K16/2863 , C07K2317/21 , C07K2317/24 , C07K2317/33 , C07K2317/34 , C07K2317/51 , C07K2317/515 , C07K2317/52 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/76 , C07K2317/92 , C07K2317/94 , C12N5/10 , C12N5/12 , C12N15/117 , C12N15/63 , C12N2310/17 , A61K39/00 , A61K2300/00
Abstract: Toll Like Receptor 3 (TLR3) antibody antagonists, polynucleotides encoding TLR3 antibody antagonists or fragments thereof, and methods of making and using the foregoing are disclosed.
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公开(公告)号：US09783607B2
公开(公告)日：2017-10-10
申请号：US15142765
申请日：2016-04-29
Applicant: Janssen Biotech, Inc.
Inventor： Jacqueline Benson , Jill Carton , Mark Cunningham , Yevgeniya I. Orlovsky , Robert Rauchenberger , Raymond Sweet
CPC classification number: C07K16/244 , A61K9/0019 , A61K9/08 , A61K39/3955 , A61K47/183 , A61K47/26 , A61K2039/505 , C07K2317/21 , C07K2317/34 , C07K2317/52 , C07K2317/55 , C07K2317/565 , C07K2317/73 , C07K2317/76 , C07K2317/92 , C07K2319/00 , C07K2319/30
Abstract: A human anti-IL-23p19 antibody, including isolated nucleic acids that encode at least one anti-IL-23p19 antibody, vectors, host cells, and methods of making and using thereof have applications in diagnostic and/or therapeutic compositions, methods and devices.
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公开(公告)号：US09714287B2
公开(公告)日：2017-07-25
申请号：US15337512
申请日：2016-10-28
Applicant: Janssen Biotech, Inc.
Inventor： Jacqueline Benson , Mark Cunningham , Cynthia Duchala , Jill Giles-Komar , Jinquan Luo , Michael Rycyzyn , Raymond Sweet
IPC: A61K39/395 , C07K16/24 , A61K45/06 , A61K39/00
CPC classification number: A61K39/3955 , A61K39/00 , A61K45/06 , A61K2039/505 , A61K2039/55527 , A61K2039/55544 , C07K16/244 , C07K2317/30 , C07K2317/33 , C07K2317/34 , C07K2317/56 , C07K2317/565 , C07K2317/76 , C07K2317/92 , C07K2319/55 , G01N33/6869 , G01N2333/54 , Y02A50/386 , Y02A50/401 , Y02A50/41 , Y02A50/412 , Y02A50/55 , Y02A50/57 , Y02A50/58
Abstract: An anti-IL-23 antibody, including isolated nucleic acids that encode at least one anti-IL-23 antibody, vectors, host cells, transgenic animals or plants, and methods of making and using thereof have applications in diagnostic and/or therapeutic compositions, methods and devices.
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Patent Agency Ranking
公开(公告)号：US10689453B2
公开(公告)日：2020-06-23
申请号：US16382645
申请日：2019-04-12
Applicant: Janssen Biotech, Inc
Inventor： John Chen , Johan Fransson , Natalie Fursov , Damon Hamel , Thomas Malia , Galina Obmolova , Tatiana Ort , Michael Rycyzyn , Michael Scully , Raymond Sweet , Alexey Teplyakov , John Wheeler , Juan Carlos Almagro
Abstract: Human antibodies immunospecific for human CD27 are capable of blocking CD27 binding to its ligand CD70 and neutralizing bioactivity of CD27 including, but not limited to, CD27 intracellular signaling, T-cell proliferation and activation, B-cell proliferation and differentiation, plasmablast formation and alleviation of antibody responses, stimulation of tumor cells by CD70, and the production of soluble mediators from T and B-cells. The antibodies are useful in diagnosing or treating CD27 activity associated diseases and conditions.
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公开(公告)号：US10272152B2
公开(公告)日：2019-04-30
申请号：US15626697
申请日：2017-06-19
Applicant: Janssen Biotech, Inc.
Inventor： Jacqueline Benson , Mark Cunningham , Cynthia Duchala , Jill Giles-Komar , Jinquan Luo , Michael Rycyzyn , Raymond Sweet
IPC: A61K39/395 , C07K16/24 , G01N33/68 , A61K45/06 , A61K39/00
Abstract: An anti-IL-23 antibody, including isolated nucleic acids that encode at least one anti-IL-23 antibody, vectors, host cells, transgenic animals or plants, and methods of making and using thereof have applications in diagnostic and/or therapeutic compositions, methods and devices.
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8.发明授权Method of treating an inflammatory condition by administering toll-like 3 receptor antagonists 有权通过施用toll样3受体拮抗剂治疗炎性病症的方法公开(公告)号：US09522957B2
公开(公告)日：2016-12-20
申请号：US13973187
申请日：2013-08-22
Applicant: Janssen Biotech, Inc.
Inventor： Mark Cunningham , Yiqing Feng , Katharine Heeringa , Jinquan Luo , Robert Rauchenberger , Mark Rutz , Lani San Mateo , Robert Sarisky , Raymond Sweet , Fang Teng , Alexey Teplyakov , Sheng-Jiun Wu
IPC: A61K39/395 , C07K16/28 , C07H21/04 , C12N15/117 , C07K14/705 , A61K39/00 , C07K16/18 , C12N5/10 , C12N5/12 , C12N15/63
CPC classification number: C07K16/2896 , A61K39/39533 , A61K39/3955 , A61K2039/505 , C07H21/04 , C07K14/705 , C07K16/18 , C07K16/28 , C07K16/2863 , C07K2317/21 , C07K2317/24 , C07K2317/33 , C07K2317/34 , C07K2317/51 , C07K2317/515 , C07K2317/52 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/76 , C07K2317/92 , C07K2317/94 , C12N5/10 , C12N5/12 , C12N15/117 , C12N15/63 , C12N2310/17 , A61K39/00 , A61K2300/00
Abstract: Toll Like Receptor 3 (TLR3) antibody antagonists, polynucleotides encoding TLR3 antibody antagonists or fragments thereof, and methods of making and using the foregoing are disclosed.
Abstract translation: 公开了Toll样受体3（TLR3）抗体拮抗剂，编码TLR3抗体拮抗剂或其片段的多核苷酸，以及制备和使用前述物质的方法。
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公开(公告)号：US20150329634A1
公开(公告)日：2015-11-19
申请号：US14812375
申请日：2015-07-29
Applicant: Janssen Biotech, Inc.
Inventor： Jacqueline Benson , Mark Cunningham , Cynthia Duchala , Jill M. Giles-Komar , Jinquan Luo , Michael A. Rycyzyn , Raymond Sweet
IPC: C07K16/24
CPC classification number: A61K39/3955 , A61K39/00 , A61K45/06 , A61K2039/505 , A61K2039/55527 , A61K2039/55544 , C07K16/244 , C07K2317/30 , C07K2317/33 , C07K2317/34 , C07K2317/56 , C07K2317/565 , C07K2317/76 , C07K2317/92 , C07K2319/55 , G01N33/6869 , G01N2333/54 , Y02A50/386 , Y02A50/401 , Y02A50/41 , Y02A50/412 , Y02A50/55 , Y02A50/57 , Y02A50/58
Abstract: An anti-IL-23 antibody, including isolated nucleic acids that encode at least one anti-IL-23 antibody, vectors, host cells, transgenic animals or plants, and methods of making and using thereof have applications in diagnostic and/or therapeutic compositions, methods and devices.
Abstract translation: 抗IL-23抗体，包括编码至少一种抗IL-23抗体，载体，宿主细胞，转基因动物或植物的分离的核酸及其制备和使用的方法具有在诊断和/或治疗组合物中的应用 ，方法和设备。
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公开(公告)号：US09127058B2
公开(公告)日：2015-09-08
申请号：US14068670
申请日：2013-10-31
Applicant: Janssen Biotech, Inc.
Inventor： Jacqueline Benson , Mark Cunningham , Cynthia Duchala , Jill M. Giles-Komar , Jinquan Luo , Michael A. Rycyzyn , Raymond Sweet
CPC classification number: A61K39/3955 , A61K39/00 , A61K45/06 , A61K2039/505 , A61K2039/55527 , A61K2039/55544 , C07K16/244 , C07K2317/30 , C07K2317/33 , C07K2317/34 , C07K2317/56 , C07K2317/565 , C07K2317/76 , C07K2317/92 , C07K2319/55 , G01N33/6869 , G01N2333/54 , Y02A50/386 , Y02A50/401 , Y02A50/41 , Y02A50/412 , Y02A50/55 , Y02A50/57 , Y02A50/58
Abstract: An anti-IL-23 antibody, including isolated nucleic acids that encode at least one anti-IL-23 antibody, vectors, host cells, transgenic animals or plants, and methods of making and using thereof have applications in diagnostic and/or therapeutic compositions, methods and devices.
Abstract translation: 抗IL-23抗体，包括编码至少一种抗IL-23抗体，载体，宿主细胞，转基因动物或植物的分离的核酸及其制备和使用的方法具有诊断和/或治疗组合物中的应用 ，方法和设备。
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