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公开(公告)号：US20180143137A1
公开(公告)日：2018-05-24
申请号：US15858818
申请日：2017-12-29
Applicant: HAMAMATSU PHOTONICS K.K.
Inventor： Naoya MATSUMOTO , Koyo WATANABE , Hirotoshi TERADA
CPC classification number: G01N21/6458 , G01B9/021 , G01B11/24 , G01N21/64 , G01N21/6486 , G01N2201/06113 , G02B5/32 , G02B21/00 , G02B21/08 , G02B21/26 , G02B21/361 , G02B21/365 , G02B27/0068 , G03H1/0005 , G03H2001/005
Abstract: A microscope apparatus (1A) includes a biological sample table (11) that supports the biological sample (B), an objective lens (12) disposed to face the biological sample table (11), a laser light source (13) that outputs light with which the biological sample (B) is irradiated via the objective lens (12), a shape measurement unit (20) that acquires a surface shape of the biological sample (B), a control unit (40) that generates aberration correction hologram data for correcting an aberration caused by the surface shape of the biological sample (B) on the basis of information acquired in the shape measurement unit (20), a first spatial light modulator (33) to which a hologram based on the aberration correction hologram data is presented and that modulates the light output from the laser light source (31), and a photodetector (37) that detects an intensity of light to be detected (L2) generated in the biological sample (B). Thus, a microscope apparatus and an image acquisition method capable of suppressing a decrease in condensing intensity of irradiation light inside a biological sample and spreading of a condensing shape are realized.
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公开(公告)号：US20170030776A1
公开(公告)日：2017-02-02
申请号：US15303900
申请日：2015-04-08
Applicant: HAMAMATSU PHOTONICS K.K.
Inventor： Takashi INOUE , Koyo WATANABE , Koji TAKAHASHI , Naoya MATSUMOTO
CPC classification number: G01J11/00 , G01J9/00 , G02B5/32 , G02F2203/56
Abstract: A waveform measurement device includes an input spectrum acquisition unit for acquiring an input intensity spectrum being an intensity spectrum of pulsed light, an optical element inputting the pulsed light and outputting light having an intensity spectrum corresponding to a phase spectrum of the pulsed light, an output spectrum acquisition unit for acquiring an output intensity spectrum being an intensity spectrum of the light output from the optical element, and a phase spectrum determination unit for determining the phase spectrum of the pulsed light by comparing an output intensity spectrum calculated when the pulsed light having an input intensity spectrum and a virtual phase spectrum is assumed to be input to the optical element with the output intensity spectrum acquired in the output spectrum acquisition unit. The phase spectrum determination unit sets the virtual phase spectrum by deforming the control phase spectrum.
Abstract translation: 波形测量装置包括：输入频谱获取单元，用于获取作为脉冲光的强度谱的输入强度谱;输入脉冲光的光学元件，并输出具有与脉冲光的相位谱对应的强度光谱的光;输出 光谱获取单元，用于获取作为从光学元件输出的光的强度谱的输出强度谱;以及相位谱确定单元，用于通过比较当脉冲光具有 假设输入强度谱和虚拟相位谱被输入到具有在输出频谱获取单元中获取的输出强度谱的光学元件。 相位谱确定单元通过使控制相位频谱变形来设定虚拟相位频谱。
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公开(公告)号：US20240192082A1
公开(公告)日：2024-06-13
申请号：US18286250
申请日：2022-03-14
Applicant: HAMAMATSU PHOTONICS K.K.
Inventor： Koyo WATANABE , Hisanari TAKAHASHI , Takashi INOUE
IPC: G01M11/02
CPC classification number: G01M11/0207
Abstract: A dispersion measuring device includes a pulse forming unit, a light detection unit, a control unit, and an arithmetic operation unit. The control unit selectively outputs a first phase pattern and a second phase pattern. The pulse forming unit forms an optical pulse train from initial pulsed light, the optical pulse train including a plurality of optical pulses having a time difference from each other and having different center wavelengths from each other. The light detection unit detects a temporal waveform of the optical pulse train. The arithmetic operation unit estimates a wavelength dispersion amount of a measurement object based on a feature amount of the temporal waveform of the optical pulse train. When the first phase pattern is output, a pulse having a long center wavelength is generated first. When the second phase pattern is output, a pulse having a short center wavelength is generated first.
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24.发明公开公开(公告)号：US20240003744A1
公开(公告)日：2024-01-04
申请号：US18368830
申请日：2023-09-15
Applicant: HAMAMATSU PHOTONICS K.K.
Inventor： Koyo WATANABE , Kyohei SHIGEMATSU , Takashi INOUE
CPC classification number: G01J3/453 , G01J11/00 , G01M11/3163 , H01S3/0057 , H01S3/0092
Abstract: A dispersion measurement apparatus includes a pulse forming unit, a correlation optical system, a photodetection unit, and an operation unit. The pulse forming unit forms a light pulse train including a plurality of light pulses having time differences and center wavelengths different from each other from a measurement target light pulse output from a pulsed laser light source. The correlation optical system receives the light pulse train output from the pulse forming unit and outputs correlation light including a cross-correlation or an autocorrelation of the light pulse train. The photodetection unit detects a temporal waveform of the correlation light output from the correlation optical system. The operation unit estimates a wavelength dispersion amount of the pulsed laser light source based on a feature value of the temporal waveform of the correlation light.
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公开(公告)号：US20230333007A1
公开(公告)日：2023-10-19
申请号：US18026173
申请日：2021-07-05
Applicant: HAMAMATSU PHOTONICS K.K.
Inventor： Koyo WATANABE , Hisanari TAKAHASHI , Kyohei SHIGEMATSU , Takashi INOUE
IPC: G01N21/31
CPC classification number: G01N21/31 , G01N2201/0634
Abstract: A dispersion measurement apparatus includes a pulse forming unit, an imaging unit, and an operation unit. The pulse forming unit forms a light pulse train including a plurality of light pulses having time differences and center wavelengths different from each other from a light pulse output from a pulsed laser light source. The imaging unit includes an image sensor capable of performing imaging at an imaging interval shorter than a minimum peak interval of the light pulse train, and images a light pulse train passed through a measurement object to generate imaging data. The operation unit receives the imaging data, detects a temporal waveform of the light pulse train for each pixel of the image sensor, and estimates a wavelength dispersion amount of the measurement object for each pixel of the image sensor based on a feature value of the temporal waveform.
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Patent Agency Ranking
公开(公告)号：US20230304926A1
公开(公告)日：2023-09-28
申请号：US18120533
申请日：2023-03-13
Applicant: HAMAMATSU PHOTONICS K.K.
Inventor： Hisanari TAKAHASHI , Koyo WATANABE , Hiroshi SATOZONO , Kyohei SHIGEMATSU , Takashi INOUE
CPC classification number: G01N21/39 , G01N21/27 , G01N21/314 , G01N2021/1789
Abstract: A time response measurement apparatus includes a pulse formation unit, an attenuation unit, a waveform measurement unit, and an analysis unit. The pulse formation unit generates first pulsed light including a wavelength of pump light, second pulsed light including a wavelength of probe light, and third pulsed light including the wavelength of the pump light and the wavelength of the probe light, on a common optical axis. The attenuation unit transmits the first pulsed light, the second pulsed light, and the third pulsed light output from a sample arranged on the optical axis after being incident on the sample. An attenuation rate for the pump light is larger than an attenuation rate for the probe light. The analysis unit obtains a time response of the sample based on temporal waveforms of the first pulsed light, the second pulsed light, and the third pulsed light having passed through the attenuation unit.
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27.发明公开公开(公告)号：US20230168487A1
公开(公告)日：2023-06-01
申请号：US17921205
申请日：2021-01-20
Applicant: HAMAMATSU PHOTONICS K.K.
Inventor： Naoya MATSUMOTO , Koyo WATANABE
CPC classification number: G02B26/02 , G02B3/06 , G02B21/06 , G02F1/01 , G02B2207/113
Abstract: A light irradiation apparatus focuses light on a surface or an inside of an object to observe or process the object, and includes a laser light source, a lens, a lens, a mask, a wave plate, and a lens. The mask is a multi-ring mask for spatially intensity-modulating input light in a beam cross-section and outputting modulated light, and includes a plurality of ring-shaped light-shielding areas provided around a center position, and a transmitting area provided between two adjacent light-shielding areas out of the plurality of light-shielding areas. A radial width of each of the two adjacent light-shielding areas out of the plurality of light-shielding areas is larger than a radial width of the transmitting area provided between the two light-shielding areas.
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公开(公告)号：US20220236416A1
公开(公告)日：2022-07-28
申请号：US17569592
申请日：2022-01-06
Applicant: HAMAMATSU PHOTONICS K.K.
Inventor： Hisanari TAKAHASHI , Koyo WATANABE , Hiroshi SATOZONO , Takashi INOUE
Abstract: An optical measurement device includes a light pulse source, a light separator unit, a wave synthesizer unit, an optical detection unit, and a measurement unit. The light pulse source outputs a plurality of light pulses having different temporal waveforms and different center wavelengths. The light separator unit spatially separates the light pulses and causes the light pulses to be incident on a measurement object. The wave synthesizer unit synthesizes the light pulses reflected by the measurement object or transmitted through the measurement object and emits the synthesized light pulses onto one optical path. The optical detection unit receives the light pulses emitted from the wave synthesizer unit and outputs a temporal waveform signal of the light pulses. The measurement unit measures timings when the light pulses each are received by the optical detection unit or a difference between the timings on a basis of the temporal waveform signal.
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公开(公告)号：US20220178752A1
公开(公告)日：2022-06-09
申请号：US17600667
申请日：2020-03-27
Applicant: HAMAMATSU PHOTONICS K.K.
Inventor： Koyo WATANABE , Kyohei SHIGEMATSU , Takashi INOUE
Abstract: A dispersion measurement apparatus includes a pulse forming unit, a correlation optical system, a photodetection unit, and an operation unit. The pulse forming unit forms a light pulse train including a plurality of light pulses having time differences and center wavelengths different from each other from a measurement target light pulse output from a pulsed laser light source. The correlation optical system receives the light pulse train output from the pulse forming unit and outputs correlation light including a cross-correlation or an autocorrelation of the light pulse train. The photodetection unit detects a temporal waveform of the correlation light output from the correlation optical system. The operation unit estimates a wavelength dispersion amount of the pulsed laser light source based on a feature value of the temporal waveform of the correlation light.
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30.发明申请公开(公告)号：US20190258205A1
公开(公告)日：2019-08-22
申请号：US16270968
申请日：2019-02-08
Applicant: HAMAMATSU PHOTONICS K.K.
Inventor： Koyo WATANABE , Takashi INOUE
Abstract: A data generating device sets an initial candidate solution of an intensity spectrum function, a phase spectrum function, and an initial temperature and a cooling rate, generates a neighborhood solution, transforms a first waveform function of a frequency domain including the neighborhood solution and the phase spectrum function into a second waveform function of a time domain including a time-intensity waveform function and a time-phase waveform function and calculates an evaluation value representing a degree of difference between the time-intensity waveform function and the desired time-intensity waveform, sets the neighborhood solution as an n-th candidate solution for a certain probability, and lowers the temperature on the basis of the cooling rate. A decrease in the temperature acts in a direction in which the probability P is lowered when the evaluation value of the neighborhood solution is worse than the evaluation value of the candidate solution.
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