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公开(公告)号：US20150366989A1
公开(公告)日：2015-12-24
申请号：US14789873
申请日：2015-07-01
Applicant: GENENTECH, INC.
Inventor： Wei-Ching LIANG , Chie SAKANAKA , Yan WU
CPC classification number: A61K47/48638 , A61K47/6811 , A61K47/6851 , A61K47/6889 , A61K51/1045 , A61K2039/505 , C07K16/005 , C07K16/30 , C07K16/3069 , C07K2317/24 , C07K2317/54 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/567 , C07K2317/73 , C07K2317/92 , C12N9/96
Abstract: Anti-TAT226 antibodies and immunoconjugates thereof are provided. Methods of using anti-TAT226 antibodies and immunoconjugates thereof are provided.
Abstract translation: 提供抗TAT226抗体及其免疫偶联物。 提供了使用抗TAT226抗体及其免疫偶联物的方法。
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公开(公告)号：US20130115214A1
公开(公告)日：2013-05-09
申请号：US13740080
申请日：2013-01-11
Applicant: GENENTECH, INC.
Inventor： Ryan J. Watts , Yan WU
IPC: C07K16/28 , A61K31/69 , A61K31/506 , A61K31/517 , A61K31/404 , A61K31/661 , A61K39/395 , A61K31/502
CPC classification number: C07K16/2863 , A61K31/404 , A61K31/502 , A61K31/506 , A61K31/517 , A61K31/661 , A61K31/69 , A61K39/3955 , A61K39/39558 , A61K45/06 , C07K16/22 , C07K16/3023 , C07K2317/31 , C07K2317/565 , C07K2317/76 , C07K2317/92
Abstract: Novel anti-NRP1 antibodies and variants thereof having unique structural and functional characteristics are disclosed. Also provided are uses of the antibodies in research, diagnostic and therapeutic applications.
Abstract translation: 公开了具有独特结构和功能特征的新型NRP1抗体及其变体。 还提供了抗体在研究，诊断和治疗应用中的用途。
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公开(公告)号：US20240327522A1
公开(公告)日：2024-10-03
申请号：US18621505
申请日：2024-03-29
Applicant: Genentech, Inc.
Inventor： WeiYu LIN , Kelly Michele LOYET , Matthieu MASUREEL , Minh THAI , Shannon Jennifer TURLEY , Tulika TYAGI , Yan WU , Jianhuan ZHANG , Alessandra CASTIGLIONI , Cecilia Pui Chi CHIU
CPC classification number: C07K16/2842 , A61P35/00 , C07K16/2818 , A61K2039/507 , C07K2317/24 , C07K2317/52 , C07K2317/565 , C07K2317/76 , C07K2317/92
Abstract: Provided herein are anti-αvβ8 antibodies or antigen-binding portions thereof and methods of making and using the same. Further provided are methods of treating cancer with an anti-αvβ8 and a PD-1 axis antagonist.
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公开(公告)号：US20240117037A1
公开(公告)日：2024-04-11
申请号：US18345587
申请日：2023-06-30
Applicant: Genentech, Inc.
Inventor： Jane L. GROGAN , Robert J. JOHNSTON , Yan WU , Wei-Ching LIANG , Patrick LUPARDUS , Mahesh YADAV , Dhaya SESHASAYEE , Meredith HAZEN
IPC: C07K16/28 , A61K38/17 , A61K39/395 , A61K45/06 , C07K16/30
CPC classification number: C07K16/28 , A61K38/177 , A61K39/39558 , A61K45/06 , C07K16/2818 , C07K16/2827 , C07K16/2878 , C07K16/3061 , A61K2039/507 , C07K2317/56 , C07K2317/567 , C07K2317/75 , C07K2317/76 , C07K2317/92
Abstract: The invention provides anti-TIGIT (T-cell immunoreceptor with Ig and ITIM domains) antibodies and methods of using the same.
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公开(公告)号：US20240003900A1
公开(公告)日：2024-01-04
申请号：US18174889
申请日：2023-02-27
Applicant: Genentech, Inc.
Inventor： Wei-Ching LIANG , WeiYu LIN , Yan WU
CPC classification number: G01N33/6854 , C07K16/2803 , C07K2317/92 , C07K2317/565 , G01N33/54326
Abstract: Provided herein are methods for the production and identification of antibodies that bind to a desired region of a target protein.
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Patent Agency Ranking
公开(公告)号：US20210179715A1
公开(公告)日：2021-06-17
申请号：US17119753
申请日：2020-12-11
Applicant: Genentech, Inc.
Inventor： WeiYu LIN , Christoph SPIESS , Liping SUN , Yan WU , Cecilia P.C. CHIU , Walter Christian DARBONNE , Michael Andrew DILLON
IPC: C07K16/28
Abstract: Provided herein are anti-Ly6G6D (lymphocyte antigen 6 complex, locus G61) antibodies and methods of using the same.
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公开(公告)号：US20190100583A1
公开(公告)日：2019-04-04
申请号：US15965115
申请日：2018-04-27
Applicant: Genentech, Inc.
Inventor： David P. ARNOTT , Austin L. GURNEY , Philip E. HASS , James M. LEE , Yan WU
Abstract: The present invention is directed to a novel naturally occurring human cytokine that is comprised of a heterodimer of interleukin-17 and interleukin-17F designated herein as interleukin 17A/F (IL-17A/F). Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, specific antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention. Further provided herein are methods for treating degenerative cartilaginous disorders and other inflammatory diseases.
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公开(公告)号：US20180057604A1
公开(公告)日：2018-03-01
申请号：US15525821
申请日：2015-11-18
Applicant: Genentech, Inc. , Adimab LLC
Inventor： Yichin Liu , Jasvinder Atwal , Cecilia Pui Chi Chiu , Ryan J. Watts , Yan WU , Eric Krauland , Michael Feldhaus , Yin Zhang , Joy Yu Zuchero , Jessica Couch , Mark S Dennis , James A Ernst , Gregory A Lazar
CPC classification number: C07K16/40 , A61K2039/505 , C07K16/22 , C07K16/2881 , C07K2317/21 , C07K2317/24 , C07K2317/31 , C07K2317/33 , C07K2317/41 , C07K2317/52 , C07K2317/524 , C07K2317/526 , C07K2317/528 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/71 , C07K2317/72 , C07K2317/732 , C07K2317/76 , C07K2317/90 , C07K2317/92 , C07K2317/94 , C07K2319/00 , C12Y304/23046 , G01N33/6896 , G01N2333/70582 , G01N2333/96472 , G01N2800/28 , G01N2800/52
Abstract: The present invention relates to bispecific antibodies that bind to transferrin receptor and BACE1 and methods of using the same.
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公开(公告)号：US20170291940A1
公开(公告)日：2017-10-12
申请号：US15360803
申请日：2016-11-23
Applicant: Genentech, Inc.
Inventor： David P. ARNOTT , Mercedes Z. BALAZS , Nico GHILARDI , Austin L. GURNEY , Philip E. HASS , Sarah HYMOWITZ , James M. LEE , Wenjun OUYANG , Melissa A. STAROVASNIK , Yan WU
IPC: C07K16/24
CPC classification number: C07K16/244 , A61K38/2073 , A61K2039/505 , C07K14/54 , C07K2317/31 , C07K2317/33 , C07K2317/34 , C07K2317/76 , C07K2317/92 , C07K2319/30 , C07K2319/40 , G01N2500/10 , G01N2800/24 , Y02A50/463
Abstract: The present invention is directed to a novel naturally occurring human cytokine that is comprised of a heterodimer of interleukin-17 and interleukin-17F designated herein as interleukin 17A/F (IL-17A/F). Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, specific antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention. Further provided herein are methods for treating degenerative cartilaginous disorders and other inflammatory diseases.
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公开(公告)号：US20170204188A1
公开(公告)日：2017-07-20
申请号：US15356483
申请日：2016-11-18
Applicant: GENENTECH, INC.
Inventor： Avi ASHKENAZI , Jing QING , Christian WIESMANN , Yan WU
CPC classification number: C07K16/2863 , A61K39/395 , A61K39/3955 , A61K39/39558 , A61K2039/505 , C07K16/3038 , C07K16/3061 , C07K2317/24 , C07K2317/34 , C07K2317/52 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/567 , C07K2317/73 , C07K2317/732 , C07K2317/75 , C07K2317/76 , C07K2317/77 , C07K2317/92 , C07K2319/30
Abstract: The invention provides FGFR3 antibodies, and compositions comprising and methods of using these antibodies.
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