NOVEL SILICONE FILM FORMER FOR DELIVERY OF ACTIVES
    27.
    发明申请
    NOVEL SILICONE FILM FORMER FOR DELIVERY OF ACTIVES 有权
    用于交付活动的新型硅胶膜

    公开(公告)号:US20090258058A1

    公开(公告)日:2009-10-15

    申请号:US12300875

    申请日:2007-05-23

    摘要: The invention provides: a film-forming composition comprising a) a saccharide-siloxane copolymer; b) a crosslinking agent; c) one or more active/inactive ingredients; and d) optionally, a solvent, or solvent mixture, wherein the saccharide-siloxane copolymer has the following formula: R2aR1(3−a)SiO—[(SiR2R1O)m-(SiR12O)n]y-SiR1(3−a)R2a that is further formulaically defined and wherein the saccharide-siloxane copolymer is a reaction product of a functionalized organosiloxane polymer and at least one hydroxy-functional saccharide such that the organosiloxane component is covalently linked via a linking group to the saccharide component; films; and methods related thereto. The invention also provides articles of manufacture including topical and transdermal agent delivery patches comprising the novel film-forming composition and/or films.

    摘要翻译: 本发明提供:一种成膜组合物,其包含a)糖 - 硅氧烷共聚物; b)交联剂; c)一种或多种活性/非活性成分; 其中糖 - 硅氧烷共聚物具有下式:R2aR1(3-a)SiO - [(SiR2R10)m-(SiR12O)n] y-SiR1(3-a) R2a,其进一步公式定义,其中糖 - 硅氧烷共聚物是官能化有机硅氧烷聚合物和至少一种羟基官能糖的反应产物,使得有机硅氧烷组分通过连接基团与糖组分共价连接; 电影 和相关的方法。 本发明还提供了包括局部和透皮剂递送贴片的制品,其包含新的成膜组合物和/或膜。