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公开(公告)号：US20180094313A1
公开(公告)日：2018-04-05
申请号：US15831847
申请日：2017-12-05
申请人： 10X Genomics, Inc.
发明人： Benjamin Hindson , Christopher Hindson , Micheal Schnall-Levin , Kevin Ness , Mirna Jarosz , Serge Saxonov , Paul Hardenbol , Rajiv Bharadwaj , Xinying Zheng , Phillip Belgrader
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6874 , C12Q1/6804 , C12Q1/6806 , C12Q1/683 , C12Q2525/191 , C12Q2535/122 , C12Q2537/143 , C12Q2537/149 , C12Q2563/149 , C12Q2563/159 , C12Q2563/179 , C12Q2565/629
摘要： The present disclosure provides compositions, methods, systems, and devices for polynucleotide processing. Such polynucleotide processing may be useful for a variety of applications, including polynucleotide sequencing.
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公开(公告)号：US20170362587A1
公开(公告)日：2017-12-21
申请号：US15693374
申请日：2017-08-31
申请人： 10X GENOMICS, INC.
发明人： Benjamin Hindson , Serge Saxonov , Kevin Ness , Paul Hardenbol , Christopher Hindson , Donald Masquelier , Mirna Jarosz , Michael Schnall-Levin
IPC分类号： C12N15/10 , C12Q1/68 , C12N15/11 , G01N33/543
CPC分类号： C12N15/1065 , C12N15/11 , C12Q1/6806 , C12Q1/6874 , C12Q1/6876 , C12Q2600/112 , G01N33/5436
摘要： The present disclosure provides compositions, methods, systems, and devices for polynucleotide processing. Such polynucleotide processing may be useful for a variety of applications, including polynucleotide sequencing.
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公开(公告)号：US20170247757A1
公开(公告)日：2017-08-31
申请号：US15588519
申请日：2017-05-05
申请人： 10X Genomics, Inc.
发明人： Benjamin Hindson , Serge Saxonov , Kevin Ness , Paul Hardenbol , Michael Schnall-Levin , Mirna Jarosz
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6874 , C12Q1/6806 , C12Q1/6855 , C12Q1/6869 , C12Q2525/161 , C12Q2535/122 , C12Q2563/159 , C12Q2563/179 , C12Q2565/514
摘要： The present disclosure provides compositions, methods, systems, and devices for polynucleotide processing. Such polynucleotide processing may be useful for a variety of applications, including polynucleotide sequencing.
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公开(公告)号：US20150218633A1
公开(公告)日：2015-08-06
申请号：US14680808
申请日：2015-04-07
申请人： 10X Genomics, Inc.
发明人： Benjamin Hindson , Serge Saxonov , Kevin Ness , Paul Hardenbol
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6874 , C12Q1/6806 , C12Q1/683 , C12Q2525/191 , C12Q2537/143 , C12Q2563/179
摘要： The present disclosure provides compositions, methods, systems, and devices for polynucleotide processing. Such polynucleotide processing may be useful for a variety of applications, including polynucleotide sequencing.
摘要翻译： 本公开提供了用于多核苷酸处理的组合物，方法，系统和装置。 这种多核苷酸处理可用于多种应用，包括多核苷酸测序。
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25.发明公开公开(公告)号：US20240191271A1
公开(公告)日：2024-06-13
申请号：US18388735
申请日：2023-11-10
申请人： 10X GENOMICS, INC.
发明人： Paul Hardenbol , Pranav Patel , Benjamin Hindson , Paul William Wyatt , Keith Bjornson , Indira Wu , Zahra Kamila Belhocine
IPC分类号： C12P19/34 , C12Q1/6806 , C40B20/04
CPC分类号： C12P19/34 , C12Q1/6806 , C40B20/04 , B01J2219/00547 , B01J2219/00572 , B01J2219/00722
摘要： This disclosure provides methods for preparing a sequencing library including the steps of providing a template nucleic acid sequence, dNTPs, dUTP, a primer, a polymerase, a dUTP excising enzyme, and a plurality of beads including oligonucleotide adapter sequence segments; amplifying the template nucleic acid with the polymerase, dNTPs, dUTP and random hexamer to provide a complementary nucleic acid sequence including occasional dUTPs; and excising the incorporated dUTPs with the dUTP excising enzyme to provide nicks in the complementary nucleic acid sequence to provide a sequencing library.
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公开(公告)号：US11359239B2
公开(公告)日：2022-06-14
申请号：US17314526
申请日：2021-05-07
申请人： 10X GENOMICS, INC.
发明人： Benjamin Hindson , Kevin Ness , Serge Saxonov , Paul Hardenbol
IPC分类号： C12Q1/6806 , C12Q1/6855 , C12Q1/6869 , C12Q1/6874
摘要： The present disclosure provides compositions, methods, systems, and devices for polynucleotide processing. Such polynucleotide processing may be useful for a variety of applications, including polynucleotide sequencing.
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公开(公告)号：US20220098659A1
公开(公告)日：2022-03-31
申请号：US17392610
申请日：2021-08-03
申请人： 10X GENOMICS, INC.
发明人： Benjamin Hindson , Christopher Hindson , Michael Schnall-Levin , Kevin Ness , Mirna Jarosz , Serge Saxonov , Paul Hardenbol
IPC分类号： C12Q1/6874 , C12Q1/6855 , C12Q1/6806 , C12Q1/6869
摘要： The present disclosure provides compositions, methods, systems, and devices for polynucleotide processing. Such polynucleotide processing may be useful for a variety of applications, including polynucleotide sequencing.
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公开(公告)号：US11035002B2
公开(公告)日：2021-06-15
申请号：US16998425
申请日：2020-08-20
申请人： 10X GENOMICS, INC.
发明人： Benjamin Hindson , Christopher Hindson , Michael Schnall-Levin , Kevin Ness , Mirna Jarosz , Serge Saxonov , Paul Hardenbol
IPC分类号： C12Q1/68 , C12Q1/6874 , C12Q1/6855 , C12Q1/6806 , C12Q1/6869
摘要： The present disclosure provides compositions, methods, systems, and devices for polynucleotide processing. Such polynucleotide processing may be useful for a variety of applications, including polynucleotide sequencing.
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公开(公告)号：US10760124B2
公开(公告)日：2020-09-01
申请号：US15832547
申请日：2017-12-05
申请人： 10X GENOMICS, INC.
发明人： Benjamin Hindson , Christopher Hindson , Michael Schnall-Levin , Kevin Ness , Mirna Jarosz , Serge Saxonov , Paul Hardenbol , Rajiv Bharadwaj , Xinying Zheng , Phillip Belgrader
IPC分类号： C12Q1/68 , C12Q1/6874 , C12Q1/6806 , C12Q1/683 , C12Q1/6804
摘要： The present disclosure provides compositions, methods, systems, and devices for polynucleotide processing. Such polynucleotide processing may be useful for a variety of applications, including polynucleotide sequencing.
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公开(公告)号：US10584381B2
公开(公告)日：2020-03-10
申请号：US16231142
申请日：2018-12-21
申请人： 10X GENOMICS, INC.
发明人： Benjamin Hindson , Christopher Hindson , Michael Schnall-Levin , Kevin Ness , Mirna Jarosz , Serge Saxonov , Paul Hardenbol , Rajiv Bharadwaj
IPC分类号： C12Q1/68 , C12Q1/6874 , C12Q1/6855 , C12Q1/6806 , C12Q1/6869
摘要： The present disclosure provides compositions, methods, systems, and devices for polynucleotide processing. Such polynucleotide processing may be useful for a variety of applications, including polynucleotide sequencing.
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