公开(公告)号：US20090042791A1

公开(公告)日：2009-02-12

申请号：US11925411

申请日：2007-10-26

申请人： Yoshinari Kumagai ,  Toshiyuki Yoneda ,  Russell Wayne Blacher ,  Motoyoshi Nomizu

发明人： Yoshinari Kumagai ,  Toshiyuki Yoneda ,  Russell Wayne Blacher ,  Motoyoshi Nomizu

IPC分类号： A61K38/16 ,  A61K38/08 ,  A61P19/08 ,  A61K38/10

CPC分类号： A61K8/64 ,  A61K38/06 ,  A61K38/08 ,  A61K38/12 ,  A61K38/16 ,  A61K38/1709 ,  A61Q11/00 ,  C07K14/47 ,  C07K14/4705 ,  C07K14/4728 ,  C07K14/705 ,  C07K14/78

摘要： Peptide sequences comprising 10 to 50 amino acids are disclosed. The sequences are characterized by containing at least one of an integrin binding motif such as an RGD sequence, a glycosaminoglycan binding motif, and a calcium binding motif, and the remainder of amino acids contiguous with the RGD sequence in matrix extracellular phosphoglycoprotein. The sequences may be formulated for injection or dispersed in toothpaste or a mouthwash or gum patch and administered to enhance bone/tooth growth and/or reduce excessive urinary phosphate loss from the body.

摘要翻译： 公开了包含10至50个氨基酸的肽序列。 序列的特征在于含有整合素结合基序如RGD序列，糖胺聚糖结合基序和钙结合基序中的至少一种，并且与基质细胞外磷酸糖蛋白中的RGD序列连续的氨基酸的其余部分。 这些序列可以配制用于注射或分散在牙膏或漱口剂或牙龈贴片中并且被施用以增强骨/牙齿生长和/或减少体内过量的尿中磷酸盐的损失。

公开(公告)号：US07364336B2

公开(公告)日：2008-04-29

申请号：US10903296

申请日：2004-07-30

申请人： Akihiro Mori ,  Seiji Sakai ,  Toshiyuki Yoneda

发明人： Akihiro Mori ,  Seiji Sakai ,  Toshiyuki Yoneda

IPC分类号： F21V8/00

CPC分类号： G02F1/133611 ,  G02F1/133605 ,  G02F1/133615 ,  G09F13/0409 ,  G09F13/14

摘要： The present invention aims to provide a plane light source device having enhanced efficiency of use of light and high brightness uniformity.A plane light source device of the present invention is provided with a housing having an opening section, a scattering plate arranged at the opening section for scattering incoming light and a light source arranged at one side face in the housing, wherein a regular reflection section for regularly reflecting light incoming from the light source is provided in the vicinity of the light source at the bottom surface of the housing that is opposite to the scattering plate and a scatter reflection section for irregularly reflecting light incoming from the light source is provided so as to be adjacent to the regular reflection section.

摘要翻译： 本发明的目的在于提供一种具有增强的光的使用效率和高亮度均匀性的平面光源装置。 本发明的平面光源装置具有壳体，该壳体具有开口部，布置在开口部处的用于散射入射光的散射板和布置在壳体中的一个侧面处的光源，其中，用于 设置在与散射板相对的壳体的底面处的光源附近的规则反射的光，并且设置用于不规则地反射从光源入射的光的散射反射部，以便 与正反射部分相邻。

公开(公告)号：US20070147073A1

公开(公告)日：2007-06-28

申请号：US11609488

申请日：2006-12-12

申请人： Seiji Sakai ,  Toshiyuki Yoneda

发明人： Seiji Sakai ,  Toshiyuki Yoneda

IPC分类号： F21V7/04

CPC分类号： G02B6/0021 ,  G02B6/0031 ,  Y10S362/80

摘要： A surface light source device according to the invention includes a housing having an opening portion on at least one face, an LED light source held by one face of the housing opposing the opening portion, and a light guiding plate arranged at a position so as to cover the opening portion and the LED light source, wherein the light guiding plate includes a recess provided at a position corresponding to the LED light source for storing a part of the LED light source, and light quantity adjusting means provided at a bottom part of the recess for adjusting light from the LED light source, and the light quantity adjusting means includes a reflection sheet having a reflection function and a transmission function in which a total light transmittance t satisfies t≧πr2 cos θ/{(1−cos θ)(S−πr2)}, supposing that an average radius is defined as r, a distance from the LED light source is defined as H, a light-emitting area of the LED light source is defined as S, and a total light quantity is defined as L.

摘要翻译： 根据本发明的表面光源装置包括壳体，其在至少一个面上具有开口部分，由与壳体的开口部分相对的壳体的一个面保持的LED光源和布置在一个位置上的导光板， 覆盖开口部和LED光源，其中，所述导光板包括设置在与用于存储所述LED光源的一部分的所述LED光源对应的位置处的凹部，以及设置在所述LED光源的底部的光量调节装置 用于调节来自LED光源的光的凹部，光量调节装置包括具有反射功能和透射功能的反射片，其中总透光率t满足t> = pir 2cosθ / {（1-cosθ）（S-pir 2）}，假设平均半径被定义为r，则与LED光源的距离被定义为H，发光面积 的LED光源被定义为S，a d总光量定义为L.

公开(公告)号：US07229198B2

公开(公告)日：2007-06-12

申请号：US10560529

申请日：2004-06-14

申请人： Seiji Sakai ,  Akihiro Mori ,  Takashi Yamaguchi ,  Toshiyuki Yoneda

发明人： Seiji Sakai ,  Akihiro Mori ,  Takashi Yamaguchi ,  Toshiyuki Yoneda

IPC分类号： F21V33/00

CPC分类号： G02B6/0051 ,  G02B6/0023 ,  G02B6/0031 ,  G02B6/0096 ,  G02F1/133615

摘要： To obtain a planar light source which is free from brightness variations or chromaticity variations by using a point light source having a high directivity for emitted light, and to provide a liquid crystal display device capable of obtaining superior display characteristics by using this planar light source device. A planar light source device having an opening in the upper surface comprises a hollow box, a diffusion plate disposed in the opening, a reflecting plate disposed on the bottom of the hollow region of the box, and a plurality of point light sources disposed in a row along at least one side surface of the box. This planar light sources device is characterized by including a refracting element disposed parallel to the row of point light sources and between the point light sources and the hollow region for refracting the light from the point light sources, whereby the light at an incident angle at which the brightness is greatest in the luminous intensity distribution of the light radiated to the irradiation subject surface of the refracting element is refracted to the bottom surface of the box by the refracting element.

摘要翻译： 为了获得通过使用具有高发射光方向性的点光源而没有亮度变化或色度变化的平面光源，并且提供能够通过使用该平面光源装置获得优异的显示特性的液晶显示装置 。 在上表面具有开口的平面光源装置包括中空盒，设置在开口中的扩散板，设置在盒的中空区域的底部的反射板和设置在盒的中空区域中的多个点光源 沿着盒子的至少一个侧表面排列。 这种平面光源装置的特征在于包括平行于一列点光源并且在点光源和中空区域之间设置的折射元件，用于折射来自点光源的光，由此，入射角处的光以 通过折射元件将辐射到折射元件的照射对象表面的光的发光强度分布折射到盒的底面，亮度最大。

公开(公告)号：US20060181901A1

公开(公告)日：2006-08-17

申请号：US10560529

申请日：2004-06-14

申请人： Seiji Sakai ,  Akihiro Mori ,  Takashi Yamaguchi ,  Toshiyuki Yoneda

发明人： Seiji Sakai ,  Akihiro Mori ,  Takashi Yamaguchi ,  Toshiyuki Yoneda

IPC分类号： F21V7/04

CPC分类号： G02B6/0051 ,  G02B6/0023 ,  G02B6/0031 ,  G02B6/0096 ,  G02F1/133615

摘要： To obtain a planar light source which is free from brightness variations or chromaticity variations by using a point light source having a high directivity for emitted light, and to provide a liquid crystal display device capable of obtaining superior display characteristics by using this planar light source device. A planar light source device having an opening in the upper surface comprises a hollow box, a diffusion plate disposed in the opening, a reflecting plate disposed on the bottom of the hollow region of the box, and a plurality of point light sources disposed in a row along at least one side surface of the box. This planar light sources device is characterized by including a refracting element disposed parallel to the row of point light sources and between the point light sources and the hollow region for refracting the light from the point light sources, whereby the light at an incident angle at which the brightness is greatest in the luminous intensity distribution of the light radiated to the irradiation subject surface of the refracting element is refracted to the bottom surface of the box by the refracting element.

摘要翻译： 为了获得通过使用具有高发射光方向性的点光源而没有亮度变化或色度变化的平面光源，并且提供能够通过使用该平面光源装置获得优异的显示特性的液晶显示装置 。 在上表面具有开口的平面光源装置包括中空盒，设置在开口中的扩散板，设置在盒的中空区域的底部的反射板和设置在盒的中空区域中的多个点光源 沿着盒子的至少一个侧表面排列。 这种平面光源装置的特征在于包括平行于一列点光源并且在点光源和中空区域之间设置的折射元件，用于折射来自点光源的光，由此，入射角处的光以 通过折射元件将辐射到折射元件的照射对象表面的光的发光强度分布折射到盒的底面，亮度最大。

公开(公告)号：US20060132673A1

公开(公告)日：2006-06-22

申请号：US11243452

申请日：2005-10-05

申请人： Atsushi Ito ,  Akimasa Yuuki ,  Nobuyuki Zumoto ,  Toshiyuki Yoneda ,  Tomohiro Sasagawa

发明人： Atsushi Ito ,  Akimasa Yuuki ,  Nobuyuki Zumoto ,  Toshiyuki Yoneda ,  Tomohiro Sasagawa

IPC分类号： G02F1/1335

CPC分类号： G02F1/133615

摘要： A display device includes a light guide plate which includes a light transmission portion and an antireflection portion at two opposite end faces and which is provided with a light extraction portion in part of a surface, respective light sources which are arranged on outer sides of the two opposite end faces, a transmission liquid crystal panel located adjacent to the light extraction portion, and a synchronous drive unit that alternately turns ON the light sources and that displays an image that is synchronous with an alternating turn-ON operation the transmission liquid crystal panel.

摘要翻译： 显示装置包括导光板，该导光板在两个相对端面处包括光透射部分和抗反射部分，并且在一部分表面上设置有光提取部分，各个光源布置在两个外侧 相邻端面，位于与光提取部相邻的透射型液晶面板，以及同步驱动单元，其交替地接通光源，并且显示与透射型液晶面板的交替接通操作同步的图像。

公开(公告)号：US20060022935A1

公开(公告)日：2006-02-02

申请号：US11190949

申请日：2005-07-28

申请人： Seiji Sakai ,  Takuya Sakamoto ,  Toshiyuki Yoneda

发明人： Seiji Sakai ,  Takuya Sakamoto ,  Toshiyuki Yoneda

IPC分类号： G09G3/36

CPC分类号： G09G3/3413 ,  G02B6/0028 ,  G02B6/0031 ,  G02B6/0055 ,  G02B6/0076 ,  G02B6/0078 ,  G09G3/3611 ,  G09G2360/145

摘要： A surface light source device includes light source driving means for driving light sources on a light emission block basis, a light exit area being sectioned into two or more light emission blocks, light quantity detecting means for detecting light quantities on the basis of output light beams that are led out from the two or more light emission blocks, and drive control means for adjusting emission light quantities of the light sources corresponding to the respective light emission blocks on the basis of light quantities that are detected during lighting periods when only one of the light emission blocks is lit up that are subjected to light quantity detection by the light quantity detecting means.

摘要翻译： 面光源装置包括基于发光块驱动光源的光源驱动装置，被分成两个或更多个发光块的光出射区域，用于基于输出光束检测光量的光量检测装置 以及驱动控制装置，用于基于在点亮期间检测到的光量来调节与各个发光块对应的光源的发光量，当仅仅一个 发光块被点亮，由光量检测装置进行光量检测。

公开(公告)号：US20060007704A1

公开(公告)日：2006-01-12

申请号：US11176655

申请日：2005-07-08

申请人： Akihiro Mori ,  Toshiyuki Yoneda

发明人： Akihiro Mori ,  Toshiyuki Yoneda

IPC分类号： F21V7/04

CPC分类号： G02B6/0013 ,  F21Y2103/10 ,  F21Y2115/10 ,  G02B6/0021 ,  G02B6/0065 ,  G02B6/0073 ,  G02B6/0091

摘要： A surface light source device includes two or more point light sources that are arranged linearly, a light guide plate having an incident surface on which light emitted from each of the point light sources shines, for outputting input light from a front surface thereof, and light diffusing means provided on a back surface of the light guide plate, for diffusing light. The incident surface of the light guide plate is inclined toward a back side.

摘要翻译： 一种面光源装置，包括直线状配置的两个以上的点光源，具有入射面的导光板，从各个点光源射出的光从该入射面射出，从其前表面输出输入光， 设置在导光板背面的扩散装置，用于漫射光。 导光板的入射面向后侧倾斜。

公开(公告)号：US20050185394A1

公开(公告)日：2005-08-25

申请号：US11051337

申请日：2005-02-07

申请人： Takuya Sakamoto ,  Seiji Sakai ,  Toshiyuki Yoneda

发明人： Takuya Sakamoto ,  Seiji Sakai ,  Toshiyuki Yoneda

IPC分类号： F21V19/00 ,  A47B97/00 ,  F21S2/00 ,  F21S8/04 ,  F21V8/00 ,  F21V29/00 ,  F21Y101/02 ,  G02B6/00 ,  G02F1/1333 ,  G02F1/1335 ,  G02F1/13357

CPC分类号： G02F1/133603 ,  F21V29/767 ,  G02B6/0026 ,  G02B6/0055 ,  G02B6/0068 ,  G02B6/0073 ,  G02B6/0083 ,  G02B6/0085 ,  G02F1/133605 ,  G02F1/133615

摘要： A planar light source including a diffusing plate provided at an opening portion of a cabinet, a plurality of point light sources provided along a hollow region formed on a rear face side of the diffusing plate, a reflecting plate provided at inside of a cabinet relative to the diffusing plate by interposing the hollow region therebetween and arranging an end portion thereof on a side of the point light source to be inclined to a front side, and a flexible board provided with a wiring pattern for supplying power to the respective point light sources, in which an end portion of the flexible board is constituted to be arranged at inside of the cabinet by being flexed to a back side of the end portion of the reflecting plate.

摘要翻译： 一种平面光源，包括设置在机壳的开口部分处的扩散板，沿着形成在扩散板的后表面侧的中空区域设置的多个点光源，设置在柜体内部相对于 所述漫射板通过在其间插入中空区域并将其端部设置在所述点光源的一侧以向前倾斜;以及柔性板，其设置有用于向各个点光源供电的布线图案， 其中柔性板的端部构造成通过弯曲到反射板的端部的后侧而布置在机柜的内部。

公开(公告)号：US5626845A

公开(公告)日：1997-05-06

申请号：US376359

申请日：1995-01-23

申请人： Toshiyuki Yoneda ,  Gregory R. Mundy

发明人： Toshiyuki Yoneda ,  Gregory R. Mundy

IPC分类号： A61K38/00 ,  A61K45/06 ,  A61P19/08 ,  A61P35/00 ,  C07K16/22 ,  C07K16/24 ,  C07K16/26 ,  A61K39/395

CPC分类号： A61K45/06 ,  C07K16/22 ,  C07K16/241 ,  C07K16/244 ,  C07K16/26 ,  A61K38/00 ,  Y10S514/885

摘要： Materials immunoreactive with parathyroid hormone-related protein (PTH-rp) are used in the invention method to prevent and treat metastasis and cancer cell growth in bone as well as osteolysis and symptomatic sequelae thereof. Humanized antibodies are included in the invention for application of the invention method to human subjects.

摘要翻译： 在本发明方法中使用与甲状旁腺激素相关蛋白（PTH-rp）免疫反应的材料以预防和治疗骨中的转移和癌细胞生长以及骨质溶解和其症状后遗症。 人源化抗体包括在本发明中，用于将本发明方法应用于人类受试者。