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    Pulmonary aerosol delivery device and method
    11.
    发明申请
    Pulmonary aerosol delivery device and method 失效

    公开(公告)号：US20020153006A1

    公开(公告)日：2002-10-24

    申请号：US10161545

    申请日：2002-06-03

    Inventor： William C. Zimlich JR. ,  James E. Dvorsky ,  David R. Busick ,  Richard D. Peters

    IPC: A61M011/00 ,  B05B017/06 ,  B05B007/00

    CPC classification number: B05B5/002 ,  A61M11/007 ,  A61M15/0065 ,  A61M15/008 ,  A61M15/0081 ,  A61M15/0083 ,  A61M15/025 ,  B05B5/0255 ,  B05B5/1691

    Abstract: A device and method for delivering an aerosolized liquid having therapeutic properties to a user's lungs. The compact and convenient device includes a housing of such size that it can be held in a user's one hand with an exit opening in the housing for directing the aerosol to the user's mouth. The housing encloses a dispensing system for containing the liquid to be aerosolized and delivering it to an electrohydrodynamic apparatus and an electrohydrodynamic apparatus for aerosolizing the liquid and delivering the aerosol to the exit opening. The electrohydrodynamic apparatus produces a cloud of aerosolized liquid droplets having a monodispersed respirable droplet size and near zero velocity. The aerosolizing apparatus includes a plurality of spray sites each having a tip end, the spray sites cooperating with a charge source to result in an aerosolized spray from at least one tip end, a plurality of discharge electrodes downstream of the tip ends, and a plurality of reference electrodes downstream of the plurality of discharge electrodes.

    Piezoelectric polymer flow sensor and methods
    12.
    发明申请
    Piezoelectric polymer flow sensor and methods 审中-公开
    压电聚合物流量传感器及方法

    公开(公告)号：US20020104530A1

    公开(公告)日：2002-08-08

    申请号：US10005454

    申请日：2001-11-02

    Applicant: Aerogen, Inc.

    Inventor： Yehuda Ivri ,  Niall Smith ,  John Power

    IPC: A61M011/00 ,  B05B017/06 ,  A61M015/00 ,  A61M016/10

    CPC classification number: B05B17/0684 ,  A61M15/0085 ,  A61M2016/0021 ,  A61M2016/0024 ,  A61M2016/0039 ,  A61M2205/0233 ,  A61M2205/3306

    Abstract: An aerosolization system comprises a gas flow passage, and an aerosol generator comprising a plate having a plurality of apertures and a vibratable element disposed to vibrate the plate. The aerosol generator is adapted to aerosolize a liquid for delivery into the gas flow passage. A flow sensor is configured to sense a gas flow through the passage, and a controller is employed to actuate the aerosol generator based on the gas flow sensed by the flow sensor.

    Abstract translation: 雾化系统包括气流通道和气溶胶发生器，其包括具有多个孔的板和设置成使板振动的可振动元件。 气溶胶发生器适于使液体雾化以输送到气体流动通道中。 流量传感器被配置为感测通过通道的气体流量，并且使用控制器来基于由流量传感器感测的气流来致动气溶胶发生器。

    MOVING EMANATORS
    14.
    发明申请
    MOVING EMANATORS 审中-公开
    移动电动机

    公开(公告)号：US20040261790A1

    公开(公告)日：2004-12-30

    申请号：US10709440

    申请日：2004-05-05

    Applicant: MICROLIN, L.C.

    Inventor： Ashok V. Joshi ,  Lawrence Domenick

    IPC: A61M001/00 ,  A61M037/00 ,  A61M011/00 ,  B05B017/06 ,  A61M005/32 ,  A61M025/00

    CPC classification number: A61L9/145 ,  A01M1/2033 ,  A01M1/205 ,  A45D34/02 ,  A61L9/042 ,  A61L9/127

    Abstract: A controlled sustained release fluid delivery device is disclosed which has enhanced fluid delivery. The device generally includes a housing having a fluid reservoir therein for holding a fluid, at least one opening in the housing for enabling fluid delivery out of the fluid reservoir and the housing, and structures for delivering the fluid, and retaining the fluid proximate an ambient environment. Once held there, the structure holding the fluid is vibrated so as to enhance the delivery of the fluid to the ambient environment. Other aspects are also disclosed.

    Abstract translation: 公开了一种受控的持续释放流体输送装置，其具有增强的流体输送。 该装置通常包括壳体，其中具有用于保持流体的流体储存器，壳体中的至少一个开口，用于使流体从流体储存器和壳体输出，以及用于输送流体的结构，以及将流体保持在邻近环境 环境。 一旦保持在那里，保持流体的结构被振动，以便增强流体到周围环境的输送。 还公开了其他方面。

    Applicator for dispensing bioactive compositions and methods for using the same
    15.
    发明申请
    Applicator for dispensing bioactive compositions and methods for using the same 有权
    用于分配生物活性组合物的施用器及其使用方法

    公开(公告)号：US20040107961A1

    公开(公告)日：2004-06-10

    申请号：US10697615

    申请日：2003-10-29

    Inventor： Kenneth E. Trueba

    IPC: A61M011/00 ,  B05B017/06

    CPC classification number: A61M15/0086 ,  A61M15/0003 ,  A61M15/008 ,  A61M15/0085 ,  A61M15/025 ,  A61M2205/3553 ,  A61M2205/52

    Abstract: Bioactive agents are topically administered or delivered to a mucous membrane by a jet dispenser using inkjet technology, such as that used in printing. The dispenser propels precise volumes of droplets or powder for administration to a subject, such as being inhaled through the mouth or nose. A controller in the dispenser may control delivery of multiple different drugs, timing of drug administration, or change drug regimens in response to a changing medical condition of a patient, such as those monitored by a sensor in communication with the controller, for example to prevent an overdose. Administration methods are also provided, along with replacement kits.

    Abstract translation: 生物活性剂通过使用喷墨技术的喷射分配器局部施用或输送到粘膜，例如用于印刷的技术。 分配器推动精确体积的液滴或粉末，用于给予受试者，例如通过口或鼻吸入。 分配器中的控制器可以响应于诸如由与控制器通信的传感器监测的患者的改变的医疗状况来控制多种不同药物的递送，药物施用的时间或改变药物方案，例如以防止 过量 还提供管理方法以及更换工具包。

    Convertible fluid feed system with comformable reservoir and methods
    16.
    发明申请
    Convertible fluid feed system with comformable reservoir and methods 有权
    具有可变形油藏的可转换流体进料系统和方法

    公开(公告)号：US20020134372A1

    公开(公告)日：2002-09-26

    申请号：US09812987

    申请日：2001-03-20

    Inventor： Joseph P. Loeffler ,  David Rapp ,  Victor Briones ,  Ralf Bitdinger ,  Michael Klimowicz

    IPC: A61M011/00 ,  B05B017/06

    CPC classification number: A61M15/0028 ,  A61M15/0031 ,  A61M15/0033 ,  A61M15/0085 ,  B05B17/0646 ,  Y10S206/828

    Abstract: A feed system for an aerosolizer utilizes an ampoule containing a liquid and includes a housing having an ampoule region into which the ampoule is held, and a liquid receiving region that is adapted to receive liquid dispensed from the ampoule. An interface is used to couple the liquid receiving region to an aerosol generator, whereby liquid from the liquid receiving region is permitted to flow to the aerosol generator for aerosolization.

    Abstract translation: 用于气雾化器的进料系统利用含有液体的安瓿，并且包括具有安瓿保藏在其中的安瓿区域的壳体和适于接收从安瓿分配的液体的液体接收区域。 接口用于将液体接收区域耦合到气溶胶发生器，由此来自液体接收区域的液体被允许流到气溶胶发生器用于雾化。

    Methods and apparatus for controlling piezoelectric vibration
    17.
    发明申请
    Methods and apparatus for controlling piezoelectric vibration 有权
    控制压电振动的方法和装置

    公开(公告)号：US20020129813A1

    公开(公告)日：2002-09-19

    申请号：US09805498

    申请日：2001-03-13

    Inventor： Craig Litherland ,  Rob Burnside ,  Kamran Behzadian ,  Michael Klimowicz

    IPC: A61M011/00 ,  B05B017/06

    CPC classification number: B05B17/0646 ,  A61M11/005 ,  A61M15/0085 ,  B05B12/081 ,  B05B15/14 ,  B05B17/0669 ,  H01L41/042

    Abstract: A method for aerosolizing a liquid comprises providing an aerosol generator having a plate with a plurality of apertures and a piezoelectric element to vibrate the plate. Liquid is supplied to the plate, and the piezoelectric element is energized to vibrate the plate at an initial frequency. The energy level is adjusted to vibrate the plate at its instantaneous resonant frequency during aerosolization of the liquid.

    Abstract translation: 一种用于使液体雾化的方法包括提供具有多个孔的板和压电元件的气溶胶发生器，以振动板。 液体被供应到板，并且压电元件被激励以以初始频率振动板。 调整能量水平以在液体雾化期间以其瞬时谐振频率振动板。

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