公开(公告)号：US10376491B2

公开(公告)日：2019-08-13

申请号：US15560583

申请日：2016-03-22

Applicant: TASLY PHARMACEUTICAL GROUP CO., LTD.

Inventor： Xijun Yan ,  Naifeng Wu ,  He Sun ,  Kaijing Yan ,  Yonghong Zhu ,  Xiaohui Ma ,  Shunnan Zhang ,  Changwen Li ,  Xiaolin Bai ,  Ting Li ,  Lei Li ,  Yi He

IPC: A61K36/00 ,  A61K31/357 ,  A61K36/82 ,  A61K47/24 ,  A61K9/48 ,  A61K31/205 ,  A61P1/16 ,  A61K9/16 ,  A61K31/355 ,  A61K31/683 ,  A61K9/08 ,  A61K36/488

Abstract: Disclosed are a pharmaceutical composition for treating non-alcoholic fatty liver and a method for preparing same. The composition is prepared from the following hulk drugs by weight ratio: 8.75-60 parts of silibinin, 15-65 parts of phospholipid, 25-200 parts of Pu'er tea extract, and 5-50 parts of radix puerariae extract.

公开(公告)号：US10307396B2

公开(公告)日：2019-06-04

申请号：US15560568

申请日：2016-03-22

Applicant: TASLY PHARMACEUTICAL GROUP CO., LTD.

Inventor： He Sun ,  Xijun Yan ,  Naifeng Wu ,  Kaijing Yan ,  Yonghong Zhu ,  Shunnan Zhang ,  Xiaolin Bai ,  Xiaohui Ma ,  Yi He ,  Ting Li ,  Lei Li

IPC: A61K31/35 ,  A61K31/357 ,  A61K36/82 ,  A61K47/24 ,  A61K9/48 ,  A61K31/205 ,  A61P1/16 ,  A61K9/16 ,  A61K31/355 ,  A61K31/683 ,  A61K9/08 ,  A61K36/488

Abstract: A pharmaceutical composition. The pharmaceutical composition is prepared from the following raw materials in parts by weight: 8.75-60 parts of silybin, 15-65 parts of phospholipid, 25-200 parts of a Pu'er tea extract, 6.25-40 parts of vitamin E, and 8.3-60 parts of L-carnitine. The composition can be used for treating non-alcoholic fatty liver diseases.

公开(公告)号：USRE49050E1

公开(公告)日：2022-04-26

申请号：US16713533

申请日：2019-12-13

Applicant: Tasly Pharmaceutical Group Co., Ltd.

Inventor： Xijun Yan ,  Naifeng Wu ,  Kaijing Yan ,  Zhengliang Ye ,  Shunnan Zhang ,  Lihong Zhou ,  Wensheng Zhang ,  Hai'ou Dong ,  Yongfeng Zheng ,  Lijun Fan

IPC: A61K36/00 ,  A61K36/537 ,  A61K31/045 ,  A61K31/343 ,  A61K36/258 ,  A61K9/50 ,  A61K31/11 ,  A61K31/192 ,  A61K31/704 ,  A61K31/222 ,  A61K31/216

Abstract: A traditional Chinese medicine composition for treating cardiovascular disease, and a preparation thereof, particularly a micro drop pill preparation thereof, and a method for preparing the preparation; the method for preparing the micro drop pill preparation can be used to prepare drop pills, coated drop pills, and drop pill capsules with a high drug loading capacity.

公开(公告)号：US20190274962A1

公开(公告)日：2019-09-12

申请号：US16422857

申请日：2019-05-24

Applicant: TASLY PHARMACEUTICAL GROUP CO., LTD.

Inventor： Xijun Yan ,  Naifeng Wu ,  Kaijing Yan ,  Xiaobing Sun ,  Shunnan Zhang ,  Zhengliang Ye ,  Hai'ou Dong ,  Hongbo Zhang ,  Wensheng Zhang ,  Lihong Zhou ,  Chenming Li ,  Cong Chen ,  Xiaofeng Liu ,  Shiqing Wang ,  Changsheng Rong ,  Yongfeng Zheng ,  Lijun Fan

IPC: A61K9/20 ,  A61K36/481 ,  A61K36/48 ,  A61J3/06 ,  A61K45/06 ,  A61K9/50 ,  A61K36/258 ,  A61K36/537

Abstract: The present invention relates to a preparation method for a traditional Chinese medicine drop pill and a traditional Chinese medicine micro drop pill prepared by using the method, and in particular, the present invention relates to a micro drop pill preparation method with high drug-loading capacity, simple preparation process and high production rate and a micro drop pill prepared by using the method. Specially, The drop pill preparation method used comprises the following steps: (1) material melting step: heat melting a medicine and a drop pill matrix to obtain a molten medicine liquid; (2) dropping step: delivering the molten medicine liquid to a dripper, and acquiring medicine drops of the molten medicine liquid by means of vibration dropping; and, (3) condensation step: cooling the medicine drops with a cooling gas to obtain micro drop pills.

公开(公告)号：US09987320B2

公开(公告)日：2018-06-05

申请号：US14903684

申请日：2014-07-11

Applicant: TASLY PHARMACEUTICAL GROUP CO., LTD.

Inventor： Xijun Yan ,  Naifeng Wu ,  Kaijing Yan ,  Zhengliang Ye ,  Shunnan Zhang ,  Lihong Zhou ,  Wensheng Zhang ,  Hai'ou Dong ,  Yongfeng Zheng ,  Lijun Fan

IPC: A61K36/00 ,  A61K36/537 ,  A61K31/045 ,  A61K31/343 ,  A61K36/258 ,  A61K9/50 ,  A61K31/11 ,  A61K31/192 ,  A61K31/216 ,  A61K31/222 ,  A61K31/704

CPC classification number: A61K36/537 ,  A61K9/5015 ,  A61K9/5026 ,  A61K9/5042 ,  A61K9/5089 ,  A61K31/045 ,  A61K31/11 ,  A61K31/192 ,  A61K31/216 ,  A61K31/222 ,  A61K31/343 ,  A61K31/704 ,  A61K36/258 ,  A61K2300/00

Abstract: A traditional Chinese medicine composition for treating cardiovascular disease, and a preparation thereof, particularly a micro drop pill preparation thereof, and a method for preparing the preparation; the method for preparing the micro drop pill preparation can be used to prepare drop pills, coated drop pills, and drop pill capsules with a high drug loading capacity.

公开(公告)号：US20170157156A9

公开(公告)日：2017-06-08

申请号：US14903995

申请日：2014-07-11

Applicant: TASLY PHARMACEUTICAL GROUP CO., LTD.

Inventor： Xijun Yan ,  Naifeng Wu ,  Kaijing Yan ,  Zhengliang Ye ,  Shunnan Zhang ,  Lihong Zhou ,  Wensheng Zhang ,  Hai'ou Dong

IPC: A61K31/704 ,  A61K36/258 ,  A61K31/045 ,  A61K9/28 ,  A61K31/192 ,  A61K31/216 ,  A61K31/343 ,  A61K36/537 ,  A61K9/20

CPC classification number: A61K31/704 ,  A61K9/16 ,  A61K9/1664 ,  A61K9/20 ,  A61K9/2009 ,  A61K9/2013 ,  A61K9/2018 ,  A61K9/2031 ,  A61K9/2059 ,  A61K9/2068 ,  A61K9/2893 ,  A61K31/045 ,  A61K31/11 ,  A61K31/192 ,  A61K31/216 ,  A61K31/343 ,  A61K36/258 ,  A61K36/537 ,  A61K36/82 ,  A61K2300/00

Abstract: A traditional Chinese medicine composition for treating cardiovascular disease, and a preparation thereof, particularly a micro drop pill preparation thereof, and a method for preparing the preparation; the method for preparing the micro drop pill preparation can be used to prepare drop pills, coated drop pills, and drop pill capsules with a high drug loading capacity.

公开(公告)号：US12090138B2

公开(公告)日：2024-09-17

申请号：US17588033

申请日：2022-01-28

Applicant: TASLY PHARMACEUTICAL GROUP CO., LTD.

Inventor： He Sun ,  Xijun Yan ,  Naifeng Wu ,  Kaijing Yan ,  Yonghong Zhu ,  Shunnan Zhang ,  Xiaolin Bai ,  Xiaohui Ma ,  Yi He ,  Ting Li ,  Lei Li

IPC: A61K31/357 ,  A61K9/08 ,  A61K9/16 ,  A61K9/48 ,  A61K31/205 ,  A61K31/355 ,  A61K31/683 ,  A61K36/488 ,  A61K36/82 ,  A61K47/24 ,  A61P1/16

CPC classification number: A61K31/357 ,  A61K9/08 ,  A61K9/1617 ,  A61K9/1682 ,  A61K9/48 ,  A61K31/205 ,  A61K31/355 ,  A61K31/683 ,  A61K36/488 ,  A61K36/82 ,  A61K47/24 ,  A61P1/16 ,  A61K2236/19

Abstract: A pharmaceutical composition is prepared from the following raw materials (in parts by weight): silybin (8.75-60), phospholipid (15-65), a Pu'er tea extract (25-200), and vitamin E (6.25-40). The composition has the effect of treating non-alcoholic fatty liver diseases.

公开(公告)号：US09795648B2

公开(公告)日：2017-10-24

申请号：US14654151

申请日：2013-12-19

Applicant: Tasly Pharmaceutical Group Co., Ltd.

Inventor： Xijun Yan ,  Naifeng Wu ,  Shunnan Zhang ,  Jianhui Yang ,  Yan Liu ,  Xingyun Shao ,  Song Gao ,  Lina Dong ,  Xiaolin Bai ,  Yan Sun ,  Bo Xu ,  Yongfeng Zheng ,  Lijun Fan

IPC: A61K36/00 ,  A61K36/74 ,  A61K36/66 ,  A61K36/268 ,  A61K36/804 ,  A61K36/482 ,  A61K36/536 ,  A61K36/9068 ,  A61K35/618 ,  A61K36/232 ,  A61K36/48 ,  A61K36/505 ,  A61K36/65 ,  A61K36/236 ,  A61K36/486 ,  A61K36/71 ,  A61K9/16

CPC classification number: A61K36/74 ,  A61K9/1623 ,  A61K9/1652 ,  A61K35/618 ,  A61K36/232 ,  A61K36/236 ,  A61K36/268 ,  A61K36/48 ,  A61K36/482 ,  A61K36/486 ,  A61K36/505 ,  A61K36/536 ,  A61K36/65 ,  A61K36/66 ,  A61K36/71 ,  A61K36/804 ,  A61K36/9068 ,  A61K2236/00 ,  A61K2300/00

Abstract: A pharmaceutical composition for treating headache, prepared from eleven Chinese herbal medicines: Chinese angelica root, ligusticum chuanxiong, radix paeoniae lactiflorae, prepared rhizome of rehmannia, uncaria tomentosa, leatherleaf milletia, prunella vulgaris, sicklesenna seed, pearl shell, corydalis tuber, and asarum, and a proper amount of adjuvant materials. A preparation method of the pharmaceutical composition, and uses thereof in the preparation of drugs for treating various headaches, traumatic cranial nerve syndrome, dizziness and vertigo, vexation and irritability, insomnia and dreaminess.

公开(公告)号：US20160184249A1

公开(公告)日：2016-06-30

申请号：US14910088

申请日：2014-08-28

Applicant: TASLY PHARMACEUTICAL GROUP CO., LTD.

Inventor： Xijun Yan ,  Naifeng Wu ,  Shunnan Zhang ,  Ping Li ,  Zhengliang Ye ,  Lihong Zhou ,  Lianwen Qi ,  Fenglian Zhang ,  Minchao Qi ,  Zhexuan Yang ,  Wei Sun ,  Jing Yu ,  Hua Yang ,  Peng Liu ,  Xiaohui Ma ,  Hai'ou Dong ,  Wensheng Zhang ,  Lanlan Zhang ,  Chenming Li

IPC: A61K31/192 ,  A61K31/216 ,  A61K36/258 ,  A61K31/352 ,  A61K31/704 ,  A61K36/537 ,  A61K31/11 ,  A61K31/343

CPC classification number: A61K31/192 ,  A61K31/11 ,  A61K31/216 ,  A61K31/343 ,  A61K31/352 ,  A61K31/7028 ,  A61K31/704 ,  A61K36/258 ,  A61K36/537 ,  A61K2300/00

Abstract: A traditional Chinese medicine composition and preparation thereof for treating cardiovascular diseases is provided. The traditional Chinese medicine composition consists of: by weight percentage, phenolic acid derivatives 30%˜80%, tanshinones 2%˜10% and saponins 15%˜60%.

Abstract translation: 提供了一种治疗心血管疾病的中药组合物及其制备方法。 中药组合物按重量百分数计，酚酸衍生物30％〜80％，丹参酮2％〜10％，皂苷15％〜60％。

公开(公告)号：US20160143976A1

公开(公告)日：2016-05-26

申请号：US14903684

申请日：2014-07-11

Applicant: TASLY PHARMACEUTICAL GROUP CO., LTD.

Inventor： Xijun Yan ,  Naifeng Wu ,  Kaijing Yan ,  Zhengliang Ye ,  Shunnan Zhang ,  Lihong Zhou ,  Wensheng Zhang ,  Hai'ou Dong ,  Yongfeng Zheng ,  Lijun Fan

IPC: A61K36/537 ,  A61K31/045 ,  A61K36/258

CPC classification number: A61K36/537 ,  A61K9/5015 ,  A61K9/5026 ,  A61K9/5042 ,  A61K9/5089 ,  A61K31/045 ,  A61K31/11 ,  A61K31/192 ,  A61K31/216 ,  A61K31/222 ,  A61K31/343 ,  A61K31/704 ,  A61K36/258 ,  A61K2300/00

Abstract: A traditional Chinese medicine composition for treating cardiovascular disease, and a preparation thereof, particularly a micro drop pill preparation thereof, and a method for preparing the preparation; the method for preparing the micro drop pill preparation can be used to prepare drop pills, coated drop pills, and drop pill capsules with a high drug loading capacity.