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    SYSTEMS AND METHODS OF LOADING OR REMOVING LIQUIDS USED IN BIOCHEMICAL ANALYSIS
    15.
    发明申请
    SYSTEMS AND METHODS OF LOADING OR REMOVING LIQUIDS USED IN BIOCHEMICAL ANALYSIS 有权
    用于生物化学分析的装载或去除液体的系统和方法

    公开(公告)号：US20150352544A1

    公开(公告)日：2015-12-10

    申请号：US14712409

    申请日：2015-05-14

    Applicant: ILLUMINA, INC.

    Inventor： Dale Buermann ,  Sebastian Bohm ,  Alexander Hsiao

    IPC: B01L3/00

    CPC classification number: B01L3/0289 ,  B01L3/502715 ,  B01L3/502784 ,  B01L7/52 ,  B01L2200/027 ,  B01L2200/0673 ,  B01L2200/10 ,  B01L2200/143 ,  B01L2300/0816 ,  B01L2400/0406 ,  B01L2400/0415 ,  B01L2400/0427 ,  B01L2400/0487 ,  Y10T436/11

    Abstract: System configured to conduct designated reactions for biological or chemical analysis. The system includes a liquid-exchange assembly comprising an assay reservoir for holding a first liquid, a receiving cavity for holding a second liquid that is immiscible with respect to the first liquid, and an exchange port fluidically connecting the assay reservoir and the receiving cavity. The system also includes a pressure activator that is operably coupled to the assay reservoir of the liquid-exchange assembly. The pressure activator is configured to repeatedly exchange the first and second liquids by (a) flowing a designated volume of the first liquid through the exchange port into the receiving cavity and (b) flowing a designated volume of the second liquid through the exchange port into the assay reservoir. The system also includes a fluidic system that is in flow communication with the liquid-exchange assembly.

    Abstract translation: 系统配置为进行生物或化学分析的指定反应。 该系统包括液体交换组件，其包括用于保持第一液体的测定储存器，用于保持与第一液体不混溶的第二液体的接收腔以及流体连接测定储存器和接收腔的交换口。 该系统还包括可操作地耦合到液体交换组件的测定储存器的压力激活器。 压力启动器被配置为通过以下步骤来重复地交换第一和第二液体：（a）将指定体积的第一液体通过交换口流动到接收腔中，和（b）使指定体积的第二液体通过交换口流入 测定池。 该系统还包括与液体交换组件流动连通的流体系统。

    Assay instrument for detecting optical signals from samples having a controlled optics adjustment system based on the priority statuses of the samples
    16.
    发明授权
    Assay instrument for detecting optical signals from samples having a controlled optics adjustment system based on the priority statuses of the samples 有权
    用于根据样品的优先级状态从具有受控光学调节系统的样品检测光信号的测定仪器

    公开(公告)号：US09139875B2

    公开(公告)日：2015-09-22

    申请号：US14263746

    申请日：2014-04-28

    Applicant: ILLUMINA, INC.

    Inventor： Alexander Triener ,  Erik Allegoren ,  Wenyi Feng ,  Dale Buermann ,  Erik Olson ,  James Osmus

    IPC: C12Q1/68 ,  G01N21/64

    CPC classification number: C12Q1/6874 ,  C12Q1/6837 ,  G01N21/6428 ,  G01N21/645 ,  G01N21/6456

    Abstract: An optical system configured to detect optical signals during imaging sessions. The optical system includes an objective lens that has a collecting end that is positioned proximate to a sample and configured to receive optical signals therefrom. The optical system also includes a removable path compensator that is configured to be located at an imaging position between the collecting end of the objective lens and the sample. The path compensator adjusts an optical path of the light emissions when in the imaging position. Also, the optical system includes a transfer device that is configured to move the path compensator. The transfer device locates the path compensator at the imaging position for a first imaging session and removes the path compensator from the imaging position for a second imaging session.

    Abstract translation: 一种配置成在成像会话期间检测光信号的光学系统。 光学系统包括物镜，该物镜具有位于样品附近并被配置为从其接收光信号的收集端。 光学系统还包括被配置为位于物镜的收集端和样品之间的成像位置处的可移除路径补偿器。 路径补偿器在成像位置调整光发射的光路。 此外，光学系统包括被配置为移动路径补偿器的传送装置。 传送装置将路径补偿器定位在用于第一成像会话的成像位置处，并从第二成像会话的成像位置移除路径补偿器。

    Assay instrument for detecting optical signals from samples
    17.
    发明授权
    Assay instrument for detecting optical signals from samples 有权
    用于检测样品光学信号的测定仪器

    公开(公告)号：US08748789B2

    公开(公告)日：2014-06-10

    申请号：US13905633

    申请日：2013-05-30

    Applicant: Illumina, Inc.

    Inventor： Alexander Triener ,  Erik Allegoren ,  Wenyi Feng ,  Dale Buermann ,  Erik Olson ,  James Osmus

    IPC: G02B7/04

    CPC classification number: C12Q1/6874 ,  C12Q1/6837 ,  G01N21/6428 ,  G01N21/645 ,  G01N21/6456

    Abstract: An optical system configured to detect optical signals during imaging sessions. The optical system includes an objective lens that has a collecting end that is positioned proximate to a sample and configured to receive optical signals therefrom. The optical system also includes a removable path compensator that is configured to be located at an imaging position between the collecting end of the objective lens and the sample. The path compensator adjusts an optical path of the light emissions when in the imaging position. Also, the optical system includes a transfer device that is configured to move the path compensator. The transfer device locates the path compensator at the imaging position for a first imaging session and removes the path compensator from the imaging position for a second imaging session.

    Abstract translation: 一种配置成在成像会话期间检测光信号的光学系统。 光学系统包括物镜，该物镜具有位于样品附近并被配置为从其接收光信号的收集端。 光学系统还包括被配置为位于物镜的收集端和样品之间的成像位置处的可移除路径补偿器。 路径补偿器在成像位置调整光发射的光路。 此外，光学系统包括被配置为移动路径补偿器的传送装置。 传送装置将路径补偿器定位在用于第一成像会话的成像位置处，并从第二成像会话的成像位置移除路径补偿器。

    SYSTEM OR DEVICE FOR BIOCHEMICAL ANALYSIS HAVING AT LEAST ONE ELECTROOSMOTIC PUMP
    18.
    发明申请
    SYSTEM OR DEVICE FOR BIOCHEMICAL ANALYSIS HAVING AT LEAST ONE ELECTROOSMOTIC PUMP 有权
    用于生物化学分析的系统或装置，具有至少一个电动泵

    公开(公告)号：US20140080205A1

    公开(公告)日：2014-03-20

    申请号：US14085122

    申请日：2013-11-20

    Applicant: THE ARIZONA BOARD OF REGENTS FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY ,  ILLUMINA, INC.

    Inventor： Jonathan Posner ,  Kamil Salloum ,  Michal Lebl ,  Mark Reed ,  Dale Buermann ,  Matthew Hage ,  Bryan Crane ,  David Heiner ,  Robert Kain ,  Michael Schroeder

    IPC: F04B37/10

    CPC classification number: F04B37/10 ,  F04B19/00 ,  Y10T436/2575

    Abstract: An electroosmotic (EO) pump is provided that includes a housing having a pump cavity, a porous core medium and electrodes. The porous core medium is positioned within the pump cavity to form an exterior reservoir that extends at least partially about an exterior surface of the porous core medium. The porous core medium has an open inner chamber provided therein. The inner chamber represents an interior reservoir. The electrodes are positioned in the inner chamber and are positioned proximate the exterior surface. The electrodes induce flow of a fluid through the porous core medium between the interior and exterior reservoirs, wherein a gas is generated when the electrodes induce flow of the fluid. The housing has a fluid inlet to convey the fluid to one of the interior reservoir and the exterior reservoir. The housing has a fluid outlet to discharge the fluid from another of the interior reservoir and the exterior reservoir. The housing has a gas removal device to remove the gas from the pump cavity.

    Abstract translation: 提供一种电渗（EO）泵，其包括具有泵腔的壳体，多孔芯介质和电极。 多孔芯介质定位在泵腔内以形成至少部分地围绕多孔芯介质的外表面延伸的外部储存器。 多孔芯介质具有设置在其中的开放内室。 内室表示内部储存器。 电极定位在内室中并且位于外表面附近。 电极通过多孔芯介质在内部和外部储存器之间引导流体流动，其中当电极引起流体流动时产生气体。 壳体具有用于将流体输送到内部储存器和外部储存器中的一个的流体入口。 壳体具有流体出口，以从另一个内部储存器和外部储存器排出流体。 壳体具有用于从泵腔去除气体的气体去除装置。

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