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公开(公告)号：US20140099260A1
公开(公告)日：2014-04-10
申请号：US13973669
申请日：2013-08-22
Applicant: Genentech, Inc.
Inventor： Yvonne Chen , Mark Dennis , David Dornan , Kristi Elkins , Jagath Reddy Junutula , Andrew Polson , Bing Zheng
IPC: C07K16/28 , A61K45/06 , A61K39/395
CPC classification number: C07K16/2803 , A61K31/537 , A61K38/05 , A61K39/3955 , A61K39/39558 , A61K45/06 , A61K47/6803 , A61K47/6811 , A61K47/6849 , A61K47/6867 , A61K51/1027 , A61K2039/505 , C07K16/2896 , C07K16/3061 , C07K2317/24 , C07K2317/34 , C07K2317/40 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/567 , C07K2317/73 , C07K2317/92 , G01N33/57492 , Y02A50/412 , Y02A50/423
Abstract: The present invention is directed to compositions of matter useful for the treatment of hematopoietic tumor in mammals and to methods of using those compositions of matter for the same.
Abstract translation: 本发明涉及可用于治疗哺乳动物造血肿瘤的物质组合物，以及使用这些物质组合物的方法。
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公开(公告)号：US20140030282A1
公开(公告)日：2014-01-30
申请号：US13936285
申请日：2013-07-08
Applicant: Genentech, Inc.
Inventor： Paul Polakis , Andrew Polson , Susan Diane Spencer , Shang-Fan Yu , Bing Zheng
IPC: A61K47/48 , A61K45/06 , A61K31/706
CPC classification number: A61K47/6809 , A61K31/706 , A61K45/06 , A61K47/6849 , A61K47/6851 , A61K47/6867
Abstract: The invention provides anti-CD79b antibodies and immunoconjugates and methods of using the same.
Abstract translation: 本发明提供抗CD79b抗体和免疫缀合物及其使用方法。
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公开(公告)号：US20130336885A1
公开(公告)日：2013-12-19
申请号：US13853620
申请日：2013-03-29
Applicant: GENENTECH INC.
Inventor： Jo-Anne Hongo , Weiguang Mao , Paul Polakis , Andrew Polson , Rajesh Vij , Yan Wu , Wei-Ching Liang
IPC: C07K16/30 , G01N33/68 , A61K51/10 , A61K39/395
CPC classification number: C07K16/28 , A61K47/6803 , A61K47/6809 , A61K47/6817 , A61K47/6849 , A61K47/6859 , A61K47/6863 , A61K2039/505 , C07K16/30 , C07K16/3046 , C07K2317/24 , C07K2317/33 , C07K2317/73 , C07K2317/92 , G01N33/6893
Abstract: The invention provides anti-LgR5 antibodies and immunoconjugates and methods of using the same.
Abstract translation: 本发明提供抗LgR5抗体和免疫缀合物及其使用方法。
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公开(公告)号：US12016842B2
公开(公告)日：2024-06-25
申请号：US17230861
申请日：2021-04-14
Applicant: Genentech, Inc.
Inventor： Andrew Polson , Shang-Fan Yu , Yu-Waye Chu , Michael Wenger , Jamie Harue Hirata , Dan Lu
IPC: A61K39/00 , A61K31/4184 , A61K31/454 , A61K31/553 , A61K31/635 , A61K39/395 , A61K45/06 , A61K47/68 , C07K16/28 , C07K16/30
CPC classification number: A61K31/4184 , A61K31/454 , A61K31/553 , A61K31/635 , A61K39/3955 , A61K39/39558 , A61K45/06 , A61K47/6803 , A61K47/6849 , A61K47/6867 , A61K47/6889 , C07K16/2803 , C07K16/2887 , C07K16/3061 , A61K2039/507 , A61K2039/54 , A61K2039/545 , A61K2300/00 , C07K2317/24 , A61K39/39558 , A61K2300/00 , A61K31/4184 , A61K2300/00 , A61K31/635 , A61K2300/00 , A61K31/454 , A61K2300/00 , A61K31/553 , A61K2300/00 , A61K39/3955 , A61K2300/00
Abstract: Provided herein are methods of treating B-cell proliferative disorders in particular Follicular Lymphoma and/or Diffuse Large B-Cell Lymphoma using immunoconjugates comprising anti-CD79b antibodies in combination with additional therapeutic agents.
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公开(公告)号：US10941199B2
公开(公告)日：2021-03-09
申请号：US15957157
申请日：2018-04-19
Applicant: Genentech, Inc.
Inventor： Liping L. Sun , Yvonne Man-Yee Chen , Mark S. Dennis , Allen J. Ebens, Jr. , Andrew Polson
Abstract: The invention provides anti-CD79b antibodies and methods of using the same.
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Patent Agency Ranking
公开(公告)号：US20190241663A1
公开(公告)日：2019-08-08
申请号：US16167000
申请日：2018-10-22
Applicant: Genentech, Inc.
Inventor： Steven R. Leong , Andrew Polson , Paul Polakis , Yan Wu , Wei-Ching Liang , Ron Firestein
IPC: C07K16/28 , A61K47/68 , C07K16/30 , A61K51/10 , G01N33/569 , A61K39/395 , A61K38/08 , A61K47/65
CPC classification number: C07K16/2827 , A61K38/08 , A61K39/39558 , A61K47/65 , A61K47/6801 , A61K47/6809 , A61K47/6849 , A61K47/6855 , A61K51/1027 , A61K51/1051 , A61K2039/505 , C07K16/3015 , C07K2317/24 , C07K2317/33 , C07K2317/56 , C07K2317/73 , C07K2317/77 , C07K2317/92 , G01N33/56972
Abstract: The invention provides anti-B7-H4 antibodies and immunoconjugates and methods of using the same.
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公开(公告)号：US20180327492A1
公开(公告)日：2018-11-15
申请号：US15957157
申请日：2018-04-19
Applicant: Genentech, Inc.
Inventor： Liping L. Sun , Yvonne Man-Yee Chen , Mark S. Dennis , Allen J. Ebens, JR. , Andrew Polson
CPC classification number: C07K16/2803 , A61K47/6803 , A61K47/6849 , A61K2039/505 , C07K16/2809 , C07K2317/21 , C07K2317/24 , C07K2317/31 , C07K2317/34 , C07K2317/55 , C07K2317/622 , C07K2317/92
Abstract: The invention provides anti-CD79b antibodies and methods of using the same.
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公开(公告)号：US20180044420A1
公开(公告)日：2018-02-15
申请号：US15657471
申请日：2017-07-24
Applicant: Genentech, Inc.
Inventor： Bing Zheng , Andrew Polson , Cecilia Chiu , Wei-Ching Liang , Yan Wu
IPC: C07K16/28 , A61K47/68 , A61K51/10 , A61K31/706 , G01N33/574 , C07K16/30 , A61K31/5517
CPC classification number: C07K16/2851 , A61K31/5517 , A61K31/706 , A61K47/68 , A61K47/6817 , A61K47/6867 , A61K47/6889 , A61K51/1069 , A61K51/1093 , C07K16/3061 , C07K2317/14 , C07K2317/24 , C07K2317/33 , C07K2317/34 , C07K2317/52 , C07K2317/76 , C07K2317/77 , C07K2317/92 , C07K2317/94 , G01N33/57426 , G01N2333/7056
Abstract: The invention provides anti-CLL-1 antibodies and immunoconjugates and methods of using the same.
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公开(公告)号：US20170362318A1
公开(公告)日：2017-12-21
申请号：US15406583
申请日：2017-01-13
Applicant: GENENTECH, INC.
Inventor： Craig Crowley , Frederic J. De Sauvage , Dan L. Eaton , Allen Ebens, JR. , Kristi Elkins , Jo-Anne S. Hongo , Jagath Reddy Junutula , Andrew Polson , Sarajane Ross , Victoria Smith , Richard L. Vandlen , Bing Zheng
IPC: C07K16/28 , G01N33/574 , C07K16/30 , A61K47/68 , C07K14/705 , A61K38/00 , A61K39/00
CPC classification number: C07K16/2803 , A61K38/00 , A61K47/6817 , A61K47/6851 , A61K2039/505 , C07K14/705 , C07K16/30 , C07K2317/24 , C07K2317/34 , C07K2317/56 , C07K2317/624 , C07K2317/73 , C07K2317/77 , C07K2317/92 , G01N33/574
Abstract: The present invention is directed to compositions of matter useful for the treatment of hematopoietic tumor in mammals and to methods of using those compositions of matter for the same.
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20.发明授权公开(公告)号：US09695240B2
公开(公告)日：2017-07-04
申请号：US14528142
申请日：2014-10-30
Applicant: Genentech, Inc.
Inventor： Italo Beria , Michele Caruso , John A. Flygare , Vittoria Lupi , Rita Perego , Paul Polakis , Andrew Polson , Matteo Salsa , Susan D. Spencer , Barbara Valsasina , Robert L. Cohen
CPC classification number: C07K16/2863 , A61K47/64 , A61K47/6809 , C07K2317/76
Abstract: The present invention relates to conjugates of therapeutically useful anthracyclines with carriers such as polyclonal and monoclonal antibodies, proteins or peptides of natural or synthetic origin; methods for their preparation, pharmaceutical composition containing them and use thereof in treating certain mammalian tumors.
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