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公开(公告)号：US09662231B2
公开(公告)日：2017-05-30
申请号：US13840257
申请日：2013-03-15
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： Michael Huy Ngo , Samit Mustafa , Syed Hossainy , Mikael Trollsas
CPC classification number: A61F2/82 , A61F2/915 , A61F2002/91575 , B29C49/08 , B29C55/26 , B29C2793/0009 , B29L2031/753 , B29L2031/7542 , Y10T29/49863
Abstract: A medical device includes a polymer scaffold crimped to a catheter having an expansion balloon. The scaffold has a morphology resulting from a biaxially expanded tube arranged to provide a more balanced, or less anisotropic axial and radial mechanical properties. The scaffold has improved mechanical properties suited for use as a balloon expandable scaffold implanted in a peripheral vessel of the body.
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公开(公告)号：US09333113B2
公开(公告)日：2016-05-10
申请号：US13842277
申请日：2013-03-15
Applicant: ABBOTT CARDIOVASCULAR SYSTEMS INC.
Inventor： Chad Abunassar , John Stankus , Jesus Magana , David Mackiewicz , Mikael Trollsas , Syed Hossainy , Scott Perrin
CPC classification number: A61B18/1492 , A61B2018/0016 , A61B2018/00214 , A61B2018/00404 , A61B2018/00434 , A61B2018/00511 , A61B2018/00577 , A61B2018/1435 , A61B2018/1467 , A61F7/12 , A61N1/403
Abstract: A catheter apparatus for treatment of a human patient is described, the catheter apparatus having a central axis and comprising a shaping structure moveable between a delivery state having a first helical shape, and a deployed state having a second helical shape. The shaping structure is configured to have a reverse taper with a structural diameter that varies over the length of the shaping structure such that the structural diameter of the shaping structure at the proximal end is smaller than the structural diameter of the shaping structure at the distal end.
Abstract translation: 描述了用于治疗人类患者的导管装置，所述导管装置具有中心轴线，并且包括可在具有第一螺旋形状的输送状态和具有第二螺旋形状的展开状态之间移动的成形结构。 成型结构被配置为具有在成形结构的长度上变化的结构直径的倒锥形，使得近端处的成形结构的结构直径小于远端处的成形结构的结构直径 。
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公开(公告)号：US20160095961A1
公开(公告)日：2016-04-07
申请号：US14965387
申请日：2015-12-10
Applicant: ABBOTT CARDIOVASCULAR SYSTEMS INC.
Inventor： John J. Stankus , Mikael Trollsas , Syed Hossainy
CPC classification number: A61L29/085 , A61F2/82 , A61F2250/0067 , A61L29/146 , A61L29/16 , A61L31/10 , A61L31/16 , A61M25/10 , A61M25/1006 , A61M2025/1013 , A61M2025/105 , A61M2025/1075
Abstract: The present invention relates to systems for and corresponding methods of delivering a therapeutic agent to a vessel wall of a body lumen by providing a compound capable of being crosslinked after intraluminal release onto a vessel wall so that the therapeutic agent is temporarily retained at the site of delivery by the crosslinked compound.
Abstract translation: 本发明涉及通过提供能够在管腔释放到血管壁上之后能够交联的化合物将治疗剂递送到体腔的血管壁的方法和相应方法，使得治疗剂暂时保留在 由交联化合物递送。
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公开(公告)号：US20160030217A1
公开(公告)日：2016-02-04
申请号：US14881073
申请日：2015-10-12
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： Mikael Trollsas , Michael H. Ngo , Boris Anukhin , Alexander Nikanorov , Syed Hossainy , John E. Papp , Dudley Jayasinghe , Zella Solter
CPC classification number: A61F2/958 , A61F2/82 , A61F2/844 , A61F2/86 , A61F2/89 , A61F2/91 , A61F2/915 , A61F2002/825 , A61F2002/91558 , A61F2002/91566 , A61F2002/91575 , A61F2002/9522 , A61F2210/0004 , A61F2210/0014 , A61F2210/0019 , A61F2210/0076 , A61F2230/0006 , A61F2230/0008 , A61F2250/0067 , A61F2250/0096 , A61F2250/0098 , A61L27/00 , A61L31/06 , A61L31/14 , B21D39/046 , B29C35/08 , B29C2035/0838 , B29K2067/046 , B29L2023/00 , B29L2031/7543 , Y10T29/49826 , Y10T29/4987 , Y10T29/49908 , Y10T29/49925 , Y10T29/49927 , C08L67/04 , C08L71/02
Abstract: A method of manufacturing a stent is disclosed. The stent includes a minimum crimped diameter such that in the minimum crimped diameter, a pair of stent rings, between which marker support structures reside, do not make contact with the marker support structures. The crimped profile of the stent of the present invention can be as small as the crimped profile of a same stent but without the marker support structures.
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公开(公告)号：US09220819B2
公开(公告)日：2015-12-29
申请号：US13842314
申请日：2013-03-15
Applicant: ABBOTT CARDIOVASCULAR SYSTEMS INC.
Inventor： John Stankus , Mikael Trollsas , Syed Hossainy
CPC classification number: A61L29/085 , A61F2/82 , A61F2250/0067 , A61L29/146 , A61L29/16 , A61L31/10 , A61L31/16 , A61M25/10 , A61M25/1006 , A61M2025/1013 , A61M2025/105 , A61M2025/1075
Abstract: The present invention relates to systems for and corresponding methods of delivering a therapeutic agent to a vessel wall of a body lumen by providing a compound capable of being crosslinked after intraluminal release onto a vessel wall so that the therapeutic agent is temporarily retained at the site of delivery by the crosslinked compound.
Abstract translation: 本发明涉及通过提供能够在管腔释放到血管壁上之后能够交联的化合物将治疗剂递送到体腔的血管壁的方法和相应方法，使得治疗剂暂时保留在 由交联化合物递送。
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Patent Agency Ranking
公开(公告)号：US20140364935A1
公开(公告)日：2014-12-11
申请号：US13910998
申请日：2013-06-05
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： Erik David Eli , Syed Hossainy , Mikael Trollsas , Michael H. Ngo , Stephen Pacetti , Michael Green , John Papp
IPC: A61F2/07
CPC classification number: A61F2/915 , A61F2/91 , A61F2/958 , A61F2002/828 , A61F2002/91575 , A61F2002/91591 , A61F2210/0004 , A61F2220/0075 , A61F2220/0091
Abstract: A scaffold is formed by several segments joined or connected to each other by only at least one coupling. The coupling decouples the segments in the axial direction over a finite distance of axial displacement. The scaffold when implanted in a peripheral vessel reduces loading on rings of a segment due to the decoupling of the segments in the axial direction over the finite distance.
Abstract translation: 支架由仅通过至少一个联接件彼此连接或连接的若干段形成。 联轴器在轴向方向上在轴向位移的有限距离上使分段解耦。 当支架植入外周血管时，由于在有限的距离上沿着轴向方向的分段，分段的环上的载荷减小。
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公开(公告)号：US20140277344A1
公开(公告)日：2014-09-18
申请号：US13842314
申请日：2013-03-15
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： John Stankus , Mikael Trollsas , Syed Hossainy
CPC classification number: A61L29/085 , A61F2/82 , A61F2250/0067 , A61L29/146 , A61L29/16 , A61L31/10 , A61L31/16 , A61M25/10 , A61M25/1006 , A61M2025/1013 , A61M2025/105 , A61M2025/1075
Abstract: The present invention relates to systems for and corresponding methods of delivering a therapeutic agent to a vessel wall of a body lumen by providing a compound capable of being crosslinked after intraluminal release onto a vessel wall so that the therapeutic agent is temporarily retained at the site of delivery by the crosslinked compound.
Abstract translation: 本发明涉及通过提供能够在管腔释放到血管壁上之后能够交联的化合物将治疗剂递送到体腔的血管壁的方法和相应方法，使得治疗剂暂时保留在 由交联化合物递送。
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公开(公告)号：US20140058499A1
公开(公告)日：2014-02-27
申请号：US14042512
申请日：2013-09-30
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： Mikael Trollsas , Michael H. Ngo , Boris Anukhin , Alexander Nikanorov , Syed Hossainy , John E. Papp , Dudley Jayasinghe , Zella Solter
IPC: A61F2/915
CPC classification number: A61F2/958 , A61F2/82 , A61F2/844 , A61F2/86 , A61F2/89 , A61F2/91 , A61F2/915 , A61F2002/825 , A61F2002/91558 , A61F2002/91566 , A61F2002/91575 , A61F2002/9522 , A61F2210/0004 , A61F2210/0014 , A61F2210/0019 , A61F2210/0076 , A61F2230/0006 , A61F2230/0008 , A61F2250/0067 , A61F2250/0096 , A61F2250/0098 , A61L27/00 , A61L31/06 , A61L31/14 , B21D39/046 , B29C35/08 , B29C2035/0838 , B29K2067/046 , B29L2023/00 , B29L2031/7543 , Y10T29/49826 , Y10T29/4987 , Y10T29/49908 , Y10T29/49925 , Y10T29/49927 , C08L67/04 , C08L71/02
Abstract: A medical device includes a polymer scaffold crimped to a catheter having an expansion balloon. The scaffold, after being deployed by the balloon, provides a crush recovery of about 90% after the diameter of the scaffold has been pinched or crushed by 50%. The scaffold has a pattern including an asymmetric closed cell connecting links connecting the closed cells.
Abstract translation: 医疗装置包括压接到具有膨胀气囊的导管的聚合物构架。 支架在被气囊部署之后，在支架的直径被挤压或压碎50％后，提供约90％的压碎回收率。 支架具有图案，其包括连接连接封闭单元的链接的非对称封闭单元。
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公开(公告)号：US11135074B2
公开(公告)日：2021-10-05
申请号：US15785368
申请日：2017-10-16
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： Syed Hossainy , Chad J. Abunassar , Michael Huy Ngo , Erik David Eli , Santosh V. Prabhu , Mikael Trollsas , Richard Rapoza
Abstract: A medical device includes a polymer scaffold crimped to a catheter having an expansion balloon. The scaffold has a structure that produces a low late lumen loss when implanted within a peripheral vessel and also exhibits a high axial fatigue life. In a preferred embodiment the scaffold forms ring structures interconnected by links, where a ring has 12 crowns and at most two links connecting adjacent rings.
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公开(公告)号：US10709589B2
公开(公告)日：2020-07-14
申请号：US15590817
申请日：2017-05-09
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： Jana Buccola , Joel Harrington , Syed Hossainy , Mary Beth Kossuth , Annie Liu , James Oberhauser , Fuh-Wei Tang
Abstract: A method of accelerated aging of bioresorbable polymer scaffolds including exposing the scaffold to water is disclosed. The scaffold is exposed to water at a controlled temperature for a selected aging time. The functional outputs, such as radial strength, expandability, and % recoil obtained from aged scaffolds predict those of real-time aging of the scaffold. The accelerated aging factor, which is the required shelf life divided by the aging time, is significantly higher for poly(L-lactide) scaffolds tested than thermal aging.
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