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32 条记录 (耗时 0.017 秒)

    PROCESS FOR PREPARING A SOLID DOSAGE FORM
    11.
    发明申请
    PROCESS FOR PREPARING A SOLID DOSAGE FORM 审中-公开
    制备固体剂型的方法

    公开(公告)号：US20090326078A1

    公开(公告)日：2009-12-31

    申请号：US12306717

    申请日：2007-06-27

    申请人： Jean Paul Remon ,  Chris Vervaet ,  Yves Gonnissen

    发明人： Jean Paul Remon ,  Chris Vervaet ,  Yves Gonnissen

    IPC分类号： A61K47/26 ,  A61K47/10

    CPC分类号： A61K9/1623 ,  A61K9/2095

    摘要： This invention provides a process for preparing a solid dosage form, comprising:—preparing an aqueous slurry, solution or suspension of (a) a powder material, and (b) a mixture of one or more polyols and one or more maltodextrins, and—spray drying the resultant aqueous slurry, solution or suspension, thereby obtaining particles which are directly compressible into a solid dosage form being able to disintegrate in an aqueous medium within no more than 15 minutes.

    摘要翻译： 本发明提供了一种制备固体剂型的方法，包括： - 制备（a）粉末材料的水性浆液，溶液或悬浮液，和（b）一种或多种多元醇和一种或多种麦芽糖糊精的混合物， 喷雾干燥所得的含水浆料，溶液或悬浮液，从而获得直接压缩成固体剂型的颗粒，其能够在不超过15分钟的时间内在含水介质中分解。

    Process and apparatus for continuous wet granulation of power material
    13.
    发明申请
    Process and apparatus for continuous wet granulation of power material 有权
    电力材料连续湿法造粒的工艺和设备

    公开(公告)号：US20060006258A1

    公开(公告)日：2006-01-12

    申请号：US10536520

    申请日：2003-11-26

    申请人： Jean-Paul Remon ,  Chris Vervaet ,  Eseldin Keleb ,  An Vermeire

    发明人： Jean-Paul Remon ,  Chris Vervaet ,  Eseldin Keleb ,  An Vermeire

    IPC分类号： B02C19/00

    CPC分类号： B01J2/20 ,  A23P10/25 ,  A61K9/1623 ,  A61K9/1694 ,  A61K9/20 ,  B01J2/10

    摘要： An apparatus for wet granulating a powder material comprises:—a barrel having a granulation chamber and being provided with a first inlet (1) for receiving said powder material and for supplying it to said granulation chamber and with a second inlet (2) for receiving a granulating liquid and for supplying it to said granulation chamber, said granulation having an aperture (9) for discharge of granules from said barrel, and—a transporting means (S) for advancing said powder material toward the end of said granulation chamber while granulating it with the aid of said granulating liquid, said transporting means (S) comprising a first transport zone (4) at its rear end, an agglomeration zone (5) downstream from the first transport zone (4) and a second transport zone (8) at its front end, said first inlet (1) and said second inlet (2) being positioned above the first transport zone (4), wherein said aperture (9) has a shape tightly fitting the terminal portion of the transporting means (S) for directly discharging said granules from the granulation chamber. The apparatus is useful for continuously wet granulating biologically-active ingredient formulations, chemicals, detergents and foodstuffs.

    摘要翻译： 用于湿粉碎粉末材料的设备包括： - 具有造粒室的桶，并且设置有用于接收所述粉末材料并将其供应到所述造粒室的第一入口（1）和用于接收的第二入口（2） 造粒液体并将其供给到所述造粒室，所述造粒物具有用于从所述筒排出颗粒的孔（9），和用于将所述粉末材料朝着造粒室的端部推进的输送装置（S） 所述输送装置（S）在其后端包括第一输送区（4），第一输送区（4）下游的附聚区（5）和第二输送区（8） ），所述第一入口（1）和所述第二入口（2）位于所述第一输送区（4）的上方，其中所述孔（9）具有紧密配合所述第一输送区 用于从造粒室直接排出所述颗粒的输送装置（S）。 该设备可用于连续湿法制粒生物活性成分配方，化学品，洗涤剂和食品。

    Cushioning wax beads for making solid shaped articles
    14.
    发明授权
    Cushioning wax beads for making solid shaped articles 有权
    用于制成固体成型制品的缓冲蜡珠

    公开(公告)号：US06923984B1

    公开(公告)日：2005-08-02

    申请号：US09831422

    申请日：2000-07-26

    申请人： Jean Paul Remon

    发明人： Jean Paul Remon

    IPC分类号： A61J3/07 ,  A61J1/03 ,  A61K9/20 ,  A61K9/26 ,  A61K9/28 ,  A61K47/06 ,  A61K47/10 ,  A61K47/12 ,  A61K47/14 ,  A61K47/32 ,  A61K47/44

    CPC分类号： A61K9/2077

    摘要： Biologically inactive cushioning beads comprise at least one compressible cushioning component consisting essentially of a microcrystalline hydrocarbon wax or a natural wax, the said wax being at least 30% by weight of the biologically inactive cushioning beads. Such beads are useful for making solid shaped articles containing biologically active ingredients by compression.

    摘要翻译： 生物惰性缓冲珠粒包含至少一种可压缩缓冲组分，其基本上由微晶烃蜡或天然蜡组成，所述蜡为生物活性缓冲珠的至少30重量％。 这种珠可用于通过压缩制备含有生物活性成分的固体成形制品。

    Xanthohumol-based compositions
    16.
    发明授权
    Xanthohumol-based compositions 有权

    公开(公告)号：US11224558B2

    公开(公告)日：2022-01-18

    申请号：US16604245

    申请日：2018-04-12

    申请人： Jean Paul Remon

    发明人： Jean Paul Remon

    IPC分类号： A61K8/02 ,  A23L33/00 ,  A61K8/04 ,  A61K8/06 ,  A61K8/35 ,  A61K8/81 ,  A61K9/00 ,  A61K9/08 ,  A61K9/14 ,  A61K9/20 ,  A61K9/48 ,  A61K31/12 ,  A61K31/79

    摘要： This invention relates to xanthohumol-based compositions, yielded in a hot-melt extrusion process (HME) using one or more water-soluble nutritionally and/or cosmetically acceptable thermoplastic polymers, such as selected from hydroxypropylmethyl-cellulose (HPMC), a vinylpyrrolidone-vinyl acetate copolymer, and combinations thereof. The present invention also relates to topical and oral formulations comprising such extruded xanthohumol-based compositions, as well as the use of one or more water-soluble nutritionally and/or cosmetically acceptable thermoplastic polymers in a hot-melt extrusion process of xanthohumol.

    XANTHOHUMOL-BASED COMPOSITIONS
    17.
    发明申请
    XANTHOHUMOL-BASED COMPOSITIONS 审中-公开

    公开(公告)号：US20200155425A1

    公开(公告)日：2020-05-21

    申请号：US16604245

    申请日：2018-04-12

    申请人： Jean Paul Remon

    发明人： Jean Paul Remon

    IPC分类号： A61K8/02 ,  A61K8/06 ,  A61K9/48 ,  A61K8/35 ,  A23L33/00 ,  A61K9/14 ,  A61K9/08 ,  A61K31/12 ,  A61K31/79 ,  A61K9/20 ,  A61K9/00 ,  A61K8/81 ,  A61K8/04

    摘要： This invention relates to xanthohumol-based compositions, yielded in a hot-melt extrusion process (HME) using one or more water-soluble nutritionally and/or cosmetically acceptable thermoplastic polymers, such as selected from hydroxypropylmethyl-cellulose (HPMC), a vinylpyrrolidone-vinyl acetate copolymer, and combinations thereof. The present invention also relates to topical and oral formulations comprising such extruded xanthohumol-based compositions, as well as the use of one or more water-soluble nutritionally and/or cosmetically acceptable thermoplastic polymers in a hot-melt extrusion process of xanthohumol.

    Intravaginal delivery system
    18.
    发明授权
    Intravaginal delivery system 有权
    阴道分娩系统

    公开(公告)号：US09168303B2

    公开(公告)日：2015-10-27

    申请号：US14131495

    申请日：2012-07-12

    申请人： Jean Paul Remon ,  Chris Vervaet ,  Hans Verstraelen ,  Marleen Temmerman

    发明人： Jean Paul Remon ,  Chris Vervaet ,  Hans Verstraelen ,  Marleen Temmerman

    IPC分类号： A61K47/32 ,  A61K9/00 ,  A61K31/19 ,  A61K47/38

    CPC分类号： A61K47/32 ,  A61K9/0036 ,  A61K31/19 ,  A61K47/38

    摘要： The present invention in general relates to an intravaginal delivery system as well as uses thereof and methods for manufacturing and use of the same. In particular the present invention relates to an intravaginal delivery system for the controlled release of one or more organic acids, such as lactic acid; said intravaginal delivery system being characterized in that it comprises a combination of ethylene vinyl acetate (EVA) copolymers and carboxylic polymers, such as for example methacrylic acid-methacrylic ester copolymers.

    摘要翻译： 本发明一般涉及阴道内递送系统及其用途及其制造和使用方法。 特别地，本发明涉及用于控制释放一种或多种有机酸如乳酸的阴道内递送系统; 所述阴道内递送系统的特征在于其包含乙烯乙酸乙烯酯（EVA）共聚物和羧酸聚合物的组合，例如甲基丙烯酸 - 甲基丙烯酸酯共聚物。

    PROCESS AND APPARATUS FOR CONTINUOUS WET GRANULATION OF POWDER MATERIAL
    20.
    发明申请
    PROCESS AND APPARATUS FOR CONTINUOUS WET GRANULATION OF POWDER MATERIAL 有权
    连续湿法粉碎粉末材料的工艺和装置

    公开(公告)号：US20110108646A1

    公开(公告)日：2011-05-12

    申请号：US13009309

    申请日：2011-01-19

    申请人： Jean-Paul Remon ,  Chris Vervaet ,  Eseldin Keleb ,  An Vermeire

    发明人： Jean-Paul Remon ,  Chris Vervaet ,  Eseldin Keleb ,  An Vermeire

    IPC分类号： B02C21/00

    CPC分类号： B01J2/20 ,  A23P10/25 ,  A61K9/1623 ,  A61K9/1694 ,  A61K9/20 ,  B01J2/10

    摘要： An apparatus for wet granulating a powder material comprises:—a barrel having a granulation chamber and being provided with a first inlet (1) for receiving said powder material and for supplying it to said granulation chamber and with a second inlet (2) for receiving a granulating liquid and for supplying it to said granulation chamber, said granulation having an aperture (9) for discharge of granules from said barrel, and—a transporting means (S) for advancing said powder material toward the end of said granulation chamber while granulating it with the aid of said granulating liquid, said transporting means (S) comprising a first transport zone (4) at its rear end, an agglomeration zone (5) downstream from the first transport zone (4) and a second transport zone (8) at its front end, said first inlet (1) and said second inlet (2) being positioned above the first transport zone (4), wherein said aperture (9) has a shape tightly fitting the terminal portion of the transporting means (S) for directly discharging said granules from the granulation chamber. The apparatus is useful for continuously wet granulating biologically-active ingredient formulations, chemicals, detergents and foodstuffs.

    摘要翻译： 用于湿粉碎粉末材料的设备包括： - 具有造粒室的桶，并且设置有用于接收所述粉末材料并将其供应到所述造粒室的第一入口（1）和用于接收的第二入口（2） 造粒液体并将其供给到所述造粒室，所述造粒物具有用于从所述筒排出颗粒的孔（9），和用于将所述粉末材料朝着造粒室的端部推进的输送装置（S） 所述输送装置（S）在其后端包括第一输送区（4），第一输送区（4）下游的附聚区（5）和第二输送区（8） ）在其前端，所述第一入口（1）和所述第二入口（2）位于所述第一输送区（4）的上方，其中所述孔（9）具有紧密地配合所述输送装置 （S），用于从造粒室直接排出所述颗粒。 该设备可用于连续湿法制粒生物活性成分配方，化学品，洗涤剂和食品。