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公开(公告)号:US20040029221A1
公开(公告)日:2004-02-12
申请号:US10206915
申请日:2002-07-26
Applicant: Genentech, Inc.
Inventor: Kevin P. Baker , Jian Chen , Luc Desnoyers , Audrey Goddard , Paul J. Godowski , Austin L. Gurney , James Pan , Victoria Smith , Colin K. Watanabe , William I. Wood , Zemin Zhang
IPC: C12P021/02 , C12N005/06 , C07K014/435 , C07H021/04 , C12N009/00
Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
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公开(公告)号:US20030207398A1
公开(公告)日:2003-11-06
申请号:US10198759
申请日:2002-07-18
Applicant: Genentech, Inc.
Inventor: Kevin P. Baker , Jian Chen , Luc Desnoyers , Audrey Goddard , Paul J. Godowski , Austin L. Gurney , James Pan , Victoria Smith , Colin K. Watanabe , William I. Wood , Zemin Zhang
IPC: C12P021/02 , C12N005/06 , C07K014/435 , C07H021/04 , C12N009/00
CPC classification number: C07H21/04 , C07K14/435 , C12N5/06 , C12N9/00 , C12P21/02
Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
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公开(公告)号:US20030207392A1
公开(公告)日:2003-11-06
申请号:US10179509
申请日:2002-06-24
Applicant: Genentech, Inc.
Inventor: Kevin P. Baker , Jian Chen , Luc Desnoyers , Audrey Goddard , Paul J. Godowski , Austin L. Gurney , James Pan , Victoria Smith , Colin K. Watanabe , William I. Wood , Zemin Zhang
IPC: C12P021/02 , C12N005/06 , C07K014/435 , C07H021/04 , C12N009/00
Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
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公开(公告)号:US20030186306A1
公开(公告)日:2003-10-02
申请号:US10410374
申请日:2003-04-08
Applicant: Genentech, Inc.
Inventor: Jian Chen , Ellen Filvaroff , Sherman Fong , Audrey Goddard , Paul J. Godowski , Christopher Grimaldi , Austin Gurney , Hanzhong Li , Kenneth Hillan , Daniel Tumas , Menno VanLookeren , Richard Vandlen , Colin Watanabe , P. Mickey Williams , William I. Wood , Daniel Yansura
IPC: C12Q001/68 , G01N033/53 , C07H021/04 , C12P021/02 , C12N005/06 , C07K014/47
CPC classification number: C07K14/705 , A61K38/00 , C07K14/54 , G01N33/57415 , G01N33/57419 , G01N33/57423 , G01N2500/04
Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
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公开(公告)号:US20030185800A1
公开(公告)日:2003-10-02
申请号:US10418038
申请日:2003-04-17
Applicant: Genentech, Inc.
Inventor: Jian Chen , Paul Godowski , William I. Wood , Dong-Xiao Zhang
IPC: A61K038/21 , C07K014/56 , C07H021/04 , C12P021/04 , C12N005/06
CPC classification number: C07K14/555 , A01K2217/05 , A61K38/00 , C07K2319/00 , C07K2319/30
Abstract: The invention concerns a novel human interferon-null, originally designated PRO655, and its variants and derivatives. The novel interferon is related to but distinct from members of the IFN-null family and from IFNs-null and -null. Nucleic acid encoding the novel polypeptide, and methods and means for their recombinant production and use are also included.
Abstract translation: 本发明涉及一种新型人类干扰素,最初称为PRO655,其变体和衍生物。 该新型干扰素与IFN-α家族的成员和IFN-β和γ的成员相关但不同。 编码新型多肽的核酸及其重组生产和使用的方法和手段也包括在内。
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公开(公告)号:US20030180255A1
公开(公告)日:2003-09-25
申请号:US10410927
申请日:2003-04-09
Applicant: Genentech, Inc.
Inventor: Jian Chen , Ellen Filvaroff , Sherman Fong , Audrey Goddard , Paul Godowski , Christopher Grimaldi , Austin Gurney , Hanzhong Li , Kenneth Hillan , Daniel Tumas , Menno VanLookeren , Richard Vandlen , Colin Watanabe , P. Mickey Williams , William I. Wood , Daniel Yansura
IPC: C07K014/54 , A61K038/20 , C07H021/04 , C12P021/04 , C12N005/06
Abstract: The present invention is directed to novel polypeptides having sequence identity with IL-17, IL-17 receptors and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention. Further provided herein are methods for treating degenerative cartilaginous disorders and other inflammatory diseases.
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公开(公告)号:US20030170800A1
公开(公告)日:2003-09-11
申请号:US10176981
申请日:2002-06-20
Applicant: Genentech, Inc.
Inventor: Kevin P. Baker , Jian Chen , Luc Desnoyers , Audrey Goddard , Paul J. Godowski , Austin L. Gurney , James Pan , Victoria Smith , Colin K. Watanabe , William I. Wood , Zemin Zhang
IPC: C12P021/02 , C12N005/06 , C07K014/435 , C07H021/04 , C12N009/00
Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
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公开(公告)号:US20030170798A1
公开(公告)日:2003-09-11
申请号:US10176490
申请日:2002-06-20
Applicant: Genentech, Inc.
Inventor: Kevin P. Baker , Jian Chen , Luc Desnoyers , Audrey Goddard , Paul J. Godowski , Austin L. Gurney , James Pan , Victoria Smith , Colin K. Watanabe , William I. Wood , Zemin Zhang
IPC: C12P021/02 , C12N005/06 , C07K014/435 , C07H021/04 , C12N009/00
Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
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公开(公告)号:US20030166131A1
公开(公告)日:2003-09-04
申请号:US10176924
申请日:2002-06-21
Applicant: Genentech, Inc.
Inventor: Kevin P. Baker , Jian Chen , Luc Desnoyers , Audrey Goddard , Paul J. Godowski , Austin L. Gurney , James Pan , Victoria Smith , Colin K. Watanabe , William I. Wood , Zemin Zhang
IPC: C12P021/02 , C12N005/06 , C07K014/435 , C07H021/04 , C12N009/00
Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
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公开(公告)号:US20030166126A1
公开(公告)日:2003-09-04
申请号:US10176754
申请日:2002-06-20
Applicant: Genentech, Inc.
Inventor: Kevin P. Baker , Jian Chen , Luc Desnoyers , Audrey Goddard , Paul J. Godowski , Austin L. Gurney , James Pan , Victoria Smith , Colin K. Watanabe , William I. Wood , Zemin Zhang
IPC: C12P021/02 , C12N005/06 , C07K014/435 , C07H021/04 , C12N009/00
CPC classification number: C07K14/47 , A01K2217/075 , A01K2227/105 , A61K38/00 , A61K39/00 , C07K14/4748 , C07K14/705 , C07K14/82 , C07K16/00 , C07K16/18 , C07K16/28 , C07K2319/30 , C12N9/90 , C12N2799/026 , C12Q1/6816 , C12Q1/6883 , C12Q1/6886 , C12Q2600/136 , C12Q2600/158 , G01N33/5082 , G01N33/5308 , G01N33/574 , G01N33/57411 , G01N33/57415 , G01N33/57419 , G01N33/57423 , G01N33/57434 , G01N33/57484 , G01N33/57488 , G01N33/57492 , G01N2500/10 , C12Q2563/131 , C12Q2527/137
Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
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