公开(公告)号：US20070218041A1

公开(公告)日：2007-09-20

申请号：US11801367

申请日：2007-05-09

Applicant: Michelle Lu ,  Gopinathan Menon ,  Michele Duggan

Inventor： Michelle Lu ,  Gopinathan Menon ,  Michele Duggan

IPC: A61K36/00 ,  C12N5/04

CPC classification number: A61Q19/08 ,  A61K8/99 ,  A61K36/23 ,  A61K36/235 ,  A61K36/28 ,  A61K36/42 ,  A61K36/53 ,  A61K36/535 ,  A61K36/58 ,  A61K36/73 ,  A61K36/81 ,  A61K36/87 ,  A61K36/889 ,  A61Q17/00 ,  A61Q19/00 ,  A61Q19/007 ,  A61Q19/02 ,  A61Q19/10 ,  A61K2300/00

Abstract: There is disclosed a topical composition having substantially undifferentiated plant seed cells and, preferably, a pharmaceutically or cosmetically acceptable vehicle. There is also a method for topically applying the composition. There are also methods for delivering a consistent level of an active to skin, nail, lips and/or hair and for enhancing the therapeutic efficacy of a topical composition having substantially undifferentiated plant seed cells.

Abstract translation: 公开了具有基本上未分化的植物种子细胞，优选药学上或美容上可接受的载体的局部组合物。 还有一种局部施用组合物的方法。 还有一些方法可以将皮肤，指甲，嘴唇和/或头发的一致活性水平递送，并提高具有基本上未分化的植物种子细胞的局部组合物的治疗功效。

公开(公告)号：US07261769B2

公开(公告)日：2007-08-28

申请号：US10563050

申请日：2004-07-01

Applicant: Sunil Bhaskaran ,  Sevanti Mehta

Inventor： Sunil Bhaskaran ,  Sevanti Mehta

IPC: A61K36/00 ,  A01N65/00 ,  C07D311/00 ,  C09B61/00 ,  C09B67/00

CPC classification number: A61K36/38 ,  A61K36/53 ,  A61K36/58 ,  C08K5/1545 ,  C09B61/00 ,  A61K2300/00

Abstract: A method of making a red pigmented composition is disclosed which includes (a) preparing an aqueous extract of Garcinia indica fruit comprising at least one red colorant; (b) treating the extract with a cation exchange resin so that one or more red colorant associates with the resin; (c) eluting the red colorant from the resin with an eluting solution containing one or more alcohol such as methanol, ethanol and isopropanol and one or more acid such as hydrochloric acid, citric acid, acetic acid, tartaric acid and hydroxy citric acid to yield a red-colored eluate; (d) collecting and concentrating the eluate to provide a concentrate; and (e) adding an antioxidant agent and/or placing the concentrate in an aseptic container in a non-oxidizing atmosphere. A combination comprising the resulting stabilized Garcinia extract in aseptic packaging in a non-oxidizing atmosphere is also disclosed, along with methods of use.

Abstract translation: 公开了一种制备红色着色组合物的方法，其包括（a）制备包含至少一种红色着色剂的藤黄an水提取物; （b）用阳离子交换树脂处理提取物，使得一种或多种红色着色剂与树脂结合; （c）用含有一种或多种醇如甲醇，乙醇和异丙醇和一种或多种酸如盐酸，柠檬酸，乙酸，酒石酸和羟基柠檬酸的洗脱溶液从树脂中洗脱出红色着色剂，得到 红色洗脱液; （d）收集和浓缩洗脱液以提供浓缩物; 和（e）在非氧化性气氛中加入抗氧化剂和/或将浓缩物置于无菌容器中。 还公开了包含在非氧化性气氛中的无菌包装中得到的稳定的藤黄提取物的组合以及使用方法。

公开(公告)号：US20070178179A1

公开(公告)日：2007-08-02

申请号：US11519327

申请日：2006-09-11

Applicant: Vijai Lakshmi ,  Ajet Saxena ,  Rajesh Kumar ,  Raghwendra Pal ,  Satyawan Singh ,  Arvind Srivastava ,  Preeti Tiwari ,  Deepak Raina ,  Anil Rastogi ,  Mahendra Srivastava ,  Ramesh Chandra ,  Anju Puri ,  Ram Raghubir ,  Poonam Gupta ,  Narender Tadigoppula ,  Brijendra Tripathi ,  Sudhir Srivastava

Inventor： Vijai Lakshmi ,  Ajet Saxena ,  Rajesh Kumar ,  Raghwendra Pal ,  Satyawan Singh ,  Arvind Srivastava ,  Preeti Tiwari ,  Deepak Raina ,  Anil Rastogi ,  Mahendra Srivastava ,  Ramesh Chandra ,  Anju Puri ,  Ram Raghubir ,  Poonam Gupta ,  Narender Tadigoppula ,  Brijendra Tripathi ,  Sudhir Srivastava

IPC: A61K36/185

CPC classification number: A61K36/58 ,  C07D493/18

Abstract: A bioactive fraction obtained from Xylocarpus that is useful for the treatment of diabetes and dyslipidemia. This fraction can be provided in a pharmaceutical composition that is useful as antidiabetic and antidyslipidemic agent, or can be used in a method of treating diabetes and dyslipidemia in a subject. Also, a process for the preparation of bioactive fraction from Xylocarpus. Novel isomeric xyloccensins and the preparation of such compounds. Also, pharmaceutical compositions comprising a therapeutically effective amount of such novel isomeric xyloccensins optionally along with one or more pharmaceutically acceptable carriers, additives, lubricant and diluents and the use of such pharmaceutical compositions in a method for treating dyslipidemia.

Abstract translation: 从Xylocarpus得到的可用于治疗糖尿病和血脂异常的生物活性成分。 该级分可以提供在可用作抗糖尿病和抗脂肪代谢剂的药物组合物中，或可用于治疗受试者的糖尿病和血脂异常的方法。 另外，从Xylocarpus制备生物活性成分的方法。 新型异构体的木糖蛋白和这些化合物的制备。 此外，药物组合物包含治疗有效量的这种新型异构的木糖蛋白，任选地与一种或多种药学上可接受的载体，添加剂，润滑剂和稀释剂一起使用，以及这些药物组合物在治疗血脂异常的方法中的用途。

公开(公告)号：US20070116778A1

公开(公告)日：2007-05-24

申请号：US11590552

申请日：2006-11-01

Applicant: Arthur Fierro

Inventor： Arthur Fierro

IPC: A61K38/05 ,  A61K31/715 ,  A61K31/66 ,  A61K31/385 ,  A61K35/20 ,  A61K31/20 ,  A61K36/71 ,  A61K33/32 ,  A61K36/58

CPC classification number: A61K36/28 ,  A61K31/20 ,  A61K31/385 ,  A61K31/66 ,  A61K31/715 ,  A61K33/32 ,  A61K35/20 ,  A61K36/58 ,  A61K36/63 ,  A61K36/71 ,  A61K38/05 ,  A61K2300/00

Abstract: Certain compounds have been shown to provide antibacterial, antiviral, and antifungal properties. These compounds can provide some of the beneficial aspects of medicinal antibiotics without damaging or destroying beneficial bacteria in the human body. By combining these compounds into a single product in capsule form, an effective wide-spectrum natural ‘antibiotic’ can be produced, without the negative side effects of medicinal antibiotics. This product can destroy harmful bacteria, viruses, and fungi without eliminating beneficial bacteria or creating medicine-resistant strains.

Abstract translation: 已经显示某些化合物提供抗细菌，抗病毒和抗真菌性质。 这些化合物可以提供药用抗生素的一些有益方面，而不会损害或破坏人体中的有益细菌。 通过将这些化合物组合成胶囊形式的单一产品，可以生产有效的广谱天然抗生素，而没有药用抗生素的副作用。 该产品可以消除有害的细菌，病毒和真菌，而不会消除有益的细菌或产生耐药菌株。

公开(公告)号：US20050147578A1

公开(公告)日：2005-07-07

申请号：US11059964

申请日：2005-02-17

Applicant: Gopinathan Menon ,  Sujatha Dokka ,  Brian Jones

Inventor： Gopinathan Menon ,  Sujatha Dokka ,  Brian Jones

IPC: A61K8/00 ,  A61K8/14 ,  A61K8/34 ,  A61K8/89 ,  A61K8/891 ,  A61K8/96 ,  A61K8/97 ,  A61K36/18 ,  A61K36/41 ,  A61K36/424 ,  A61K36/58 ,  A61K36/889 ,  A61P17/16 ,  A61Q3/00 ,  A61Q3/02 ,  A61Q5/00 ,  A61Q19/00 ,  A61Q19/08 ,  A61K35/78 ,  A01N65/00

CPC classification number: A61Q19/08 ,  A61K8/97 ,  A61K36/41 ,  A61K36/424 ,  A61K36/58 ,  A61K36/889 ,  A61Q3/00 ,  A61Q5/00 ,  A61Q19/00 ,  A61K2300/00

Abstract: There are disclosed topical cosmetic compositions having at least one natural active ingredient and a pharmaceutically or cosmetically acceptable vehicle. There is also a method for improving the aesthetic appearance of skin, hair and/or nails that includes topically applying the compositions of the present invention.

Abstract translation: 公开了具有至少一种天然活性成分和药学上或化妆品上可接受的载体的局部化妆品组合物。 还有一种用于改善包括局部施用本发明组合物的皮肤，毛发和/或指甲的美学外观的方法。

公开(公告)号：US20050042309A1

公开(公告)日：2005-02-24

申请号：US10645809

申请日：2003-08-21

Applicant: Christopher Marrs

Inventor： Christopher Marrs

IPC: A61K31/07 ,  A61K36/287 ,  A61K36/58 ,  A61K36/63 ,  A61K36/80 ,  A61K35/78

CPC classification number: A61K31/07 ,  A61K36/287 ,  A61K36/58 ,  A61K36/63 ,  A61K36/80 ,  A61K2300/00

Abstract: The present invention features a composition including (i) an oxygen labile active agent, and (ii) a plant extract selected from Chrysanthellum extract, Neem extract, Lanatellys extract, Bacopa Monnieri extract, and Olive leaf extract.

Abstract translation: 本发明的特征在于组合物，其包含（i）氧不稳定活性剂，和（ii）选自菊花提取物，楝树提取物，蓝莓提取物，Bacopa Monnieri提取物和橄榄叶提取物的植物提取物。

公开(公告)号：US20040115146A1

公开(公告)日：2004-06-17

申请号：US10321706

申请日：2002-12-17

Applicant: Avon Products, Inc.

Inventor： Harish Mahalingam ,  Brian Jones ,  Nicole McCain

IPC: A61K007/135 ,  A61K035/78

CPC classification number: A61K8/97 ,  A61K36/11 ,  A61K36/48 ,  A61K36/484 ,  A61K36/58 ,  A61K36/746 ,  A61K36/75 ,  A61K36/81 ,  A61Q5/08 ,  A61Q19/00 ,  A61Q19/02 ,  A61Q19/08 ,  A61K2300/00

Abstract: There is provided a composition having at least one of the following active extracts Butea frondosa, Naringi crenulata, Stenoloma chusana, or any combinations thereof. There is also provided a composition having at least one of the following additional extracts Azadirachta indica, Glycyrrhiza glabra linn., Morinda citrifolia, tomato glycolipid or any combinations thereof in combination with one or more of the active extracts. The compositions and methods of the invention are effective to lighten hair, skin, lips and/or nails.

Abstract translation: 提供了具有以下活性提取物Butea frondosa，Naringi crenulata，Stenoloma chusana或其任何组合中的至少一种的组合物。 还提供了一种组合物，其具有以下另外的提取物中的至少一种：Azadirachta indica，Glycyrrhiza glabra linn。，柠檬酸吗啉，番茄糖脂或其任何组合与一种或多种活性提取物的组合。 本发明的组合物和方法有效地减轻头发，皮肤，嘴唇和/或指甲。

公开(公告)号：US20040043084A1

公开(公告)日：2004-03-04

申请号：US10427568

申请日：2003-05-01

Inventor： George Cioca ,  Vasile Ionita-Manzatu ,  Liliana George ,  Paolo U. Giacomoni ,  Andrew J. Bevacqua ,  Harvey Gedeon ,  Charles Craig Tadlock ,  Donald F. Collins ,  Thomas Mammone ,  Daniel H. Maes ,  Christina G. Fthenakis

IPC: A61K035/78 ,  C12Q001/02

CPC classification number: A61Q19/00 ,  A61K8/97 ,  A61K8/99 ,  A61K35/32 ,  A61K36/064 ,  A61K36/14 ,  A61K36/185 ,  A61K36/21 ,  A61K36/23 ,  A61K36/28 ,  A61K36/38 ,  A61K36/48 ,  A61K36/484 ,  A61K36/53 ,  A61K36/54 ,  A61K36/58 ,  A61K36/738 ,  A61K36/82 ,  A61K36/87 ,  A61K36/886 ,  A61K36/896 ,  A61K36/9068 ,  A61K38/39 ,  A61K2800/28 ,  A61K2800/85 ,  A61K2300/00

Abstract: The present invention relates to a method of modulating a selected biological activity of a naturally occurring material having one or more biological activities in an extract of the naturally occurring material, the method comprising incubating the extract in a medium in the presence of an aerobically metabolizing microorganism, under suitable aerobic conditions, for a period of time sufficient to modulate the selected activity with respect to baseline activity of the unincubated extract. The invention also relates to the bioconverted material so prepared, and the use of same in cosmetic or pharmaceutical compositions.

Abstract translation: 本发明涉及在天然存在的材料的提取物中调节具有一种或多种生物活性的天然存在物质的选定生物活性的方法，所述方法包括在有氧代谢微生物存在下将培养基中的提取物 在合适的有氧条件下，足以调节相对于未温育的提取物的基线活性的选定活性的时间。 本发明还涉及如此制备的生物转化材料及其在化妆品或药物组合物中的用途。

公开(公告)号：US20030180399A1

公开(公告)日：2003-09-25

申请号：US10101501

申请日：2002-03-19

Applicant: COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH

Inventor： Abhay Singh Chauhan ,  Kishore Babu Chalasani ,  Sridevi Surapanini ,  Sharath Kumar Yandrapu ,  Rajasekhar Kataram ,  Govardhana Maroju Chary ,  Prakash Vamanrao Diwan ,  Kondapuram Vijaya Raghavan

IPC: A61K035/78

CPC classification number: A61K36/75 ,  A61K36/53 ,  A61K36/58 ,  A61K36/87 ,  A61K2300/00

Abstract: A therapeutic or an edible composition comprising at least three of the five herbs selected from Prunus amygdales, Ocimum sanctum, Azadirachta indica, Aegle marelose and Vitus vinefera, is provided for the treatment of hyperglycemia, especially for non-insulin dependent diabetic subjects, and the herbal composition has significantly reduced the blood glucose levels in both diabetic and non-diabetic experimental subjects having elevated blood glucose levels.

Abstract translation: 提供了包含选自杏仁，黑麦，楝树，gle gle lose和维生素的五种草药中的至少三种的治疗或可食用组合物，用于治疗高血糖症，特别是对于非胰岛素依赖型糖尿病受试者， 草药组合物显着降低了具有升高的血糖水平的糖尿病和非糖尿病实验受试者的血糖水平。

公开(公告)号：US20030124205A1

公开(公告)日：2003-07-03

申请号：US10034336

申请日：2001-12-28

Applicant: AVON PRODUCTS, INC.

Inventor： Gopinathan K. Menon ,  Sujatha Dokka ,  Brian Jones

IPC: A61K035/78

CPC classification number: A61Q19/08 ,  A61K8/97 ,  A61K36/41 ,  A61K36/424 ,  A61K36/58 ,  A61K36/889 ,  A61Q3/00 ,  A61Q5/00 ,  A61Q19/00 ,  A61K2300/00

Abstract: There are disclosed topical cosmetic compositions having at least one natural active ingredient and a pharmaceutically or cosmetically acceptable vehicle. There is also a method for improving the aesthetic appearance of skin, hair and/or nails that includes topically applying the compositions of the present invention.

Abstract translation: 公开了具有至少一种天然活性成分和药学上或化妆品上可接受的载体的局部化妆品组合物。 还有一种用于改善包括局部施用本发明组合物的皮肤，毛发和/或指甲的美学外观的方法。