公开(公告)号：US20130089175A1

公开(公告)日：2013-04-11

申请号：US13365790

申请日：2012-02-03

申请人： Yaowu Mo ,  Chen Xu ,  Min Qu ,  Tiejun Dai ,  Rui Wang ,  Xiaodong Luo

发明人： Yaowu Mo ,  Chen Xu ,  Min Qu ,  Tiejun Dai ,  Rui Wang ,  Xiaodong Luo

IPC分类号： H03K29/00

CPC分类号： H04N5/347 ,  H04N5/3532 ,  H04N5/355 ,  H04N5/3745 ,  H04N5/378

摘要： An arithmetic counter circuit for high performance CMOS image sensors includes a plurality of flip-flops of a plurality of counter stages and a plurality of multiplexers of the plurality of counter stages being coupled to the plurality of flip-flops. Each of the plurality of multiplexers coupled to receive control signals including at least one of a toggle signal, a keep signal, a shift enable signal, or a mode signal. The control signals select the output of each of the plurality of multiplexers. Each of the plurality of flip-flops is coupled to be in one of a toggle state, a keep state, a reset state or a set state based on inputs received from the plurality of multiplexers. Other embodiments are described.

摘要翻译： 用于高性能CMOS图像传感器的算术计数器电路包括多个计数器级的多个触发器，并且多个计数器级的多个多路复用器耦合到多个触发器。 多个多路复用器中的每一个被耦合以接收包括切换信号，保持信号，移位使能信号或模式信号中的至少一个的控制信号。 控制信号选择多个多路复用器中的每一个的输出。 多个触发器中的每一个基于从多个多路复用器接收的输入被耦合成处于切换状态，保持状态，复位状态或设置状态之一。 描述其他实施例。

公开(公告)号：US20130088624A1

公开(公告)日：2013-04-11

申请号：US13365766

申请日：2012-02-03

申请人： Yaowu Mo ,  Chen Xu ,  Min Qu ,  Xiaodong Luo ,  Donghui Wu

发明人： Yaowu Mo ,  Chen Xu ,  Min Qu ,  Xiaodong Luo ,  Donghui Wu

IPC分类号： H04N5/335

CPC分类号： H04N5/347 ,  H04N5/3532 ,  H04N5/355 ,  H04N5/3745 ,  H04N5/378

摘要： A method of implementing high dynamic range bin algorithm in an image sensor including a pixel array with a first super row having a first integration time and a second super row having a second integration time is described. The method starts by reading out image data from the first super row into a counter. Image data from the first super row is multiplied by a factor to obtain multiplied data. The factor is a ratio between the first and the second integration times. The multiplied data is then compared with a predetermined data. The image data from the second super row is readout into the counter. If the multiplied data is larger than the predetermined data, the multiplied data from the first super row is stored in the counter. If not, the image data from the second super row is stored. Other embodiments are also described.

摘要翻译： 描述了在包括具有第一积分时间的第一超级行的像素阵列和具有第二积分时间的第二超级行的图像传感器中实现高动态范围bin算法的方法。 该方法从将第一超级行的图像数据读出到计数器开始。 来自第一超级行的图像数据乘以因子以获得相乘的数据。 因子是第一和第二积分时间之间的比率。 然后将相乘的数据与预定数据进行比较。 来自第二超级行的图像数据被读出到计数器中。 如果相乘数据大于预定数据，则来自第一超级行的相乘数据被存储在计数器中。 如果没有，则存储来自第二超级行的图像数据。 还描述了其它实施例。

公开(公告)号：US08329178B2

公开(公告)日：2012-12-11

申请号：US11883258

申请日：2006-02-15

申请人： Wayne A. Marasco ,  Jianhua Sui ,  Chen Xu

发明人： Wayne A. Marasco ,  Jianhua Sui ,  Chen Xu

IPC分类号： A61K39/395 ,  C07K16/28 ,  C07K14/47 ,  C07K16/46 ,  C07K14/715

CPC分类号： C07K16/2866 ,  A61K2039/505 ,  C07K16/005 ,  C07K2317/21 ,  C07K2317/622

摘要： The invention provides human monoclonal antibodies or fragments thereof, that specifically bind to CXCR4. Disclosed are methods of use of such antibodies for the treatment and/or prevention of a CXCR4 disease or disorder such as cancer and X4-tropic HIV-1 infection Also provided are methods of use of such antibodies and antibody fragments for the treatment or prevention of cancer metastasis. The invention provides methods of mobilizing CD34+stem cells from the bone marrow and methods of blocking chemotaxis of CXCR4-expressing cells in response to SDF-1. Also provided are methods of use of the antibodies and fragments thereof for the prevention or treatment of graft-versus-host disease. Finally, the invention provides methods of inhibiting new tumor blood vessel formation and/or tumor cell angiogenesis.

摘要翻译： 本发明提供特异性结合CXCR4的人单克隆抗体或其片段。 公开了使用这种抗体治疗和/或预防CXCR4疾病或病症如癌症和X4-嗜性HIV-1感染的方法。还提供了使用这种抗体和抗体片段来治疗或预防 癌转移。 本发明提供了从骨髓中移动CD34 +干细胞的方法以及阻断响应于SDF-1的CXCR4表达细胞趋化性的方法。 还提供了用于预防或治疗移植物抗宿主病的抗体及其片段的方法。 最后，本发明提供了抑制新的肿瘤血管形成和/或肿瘤细胞血管发生的方法。

公开(公告)号：US20120225320A1

公开(公告)日：2012-09-06

申请号：US13501471

申请日：2010-10-14

申请人： Chen Xu ,  Gary S. Silverman ,  Roman Y. Korotkov ,  Robert G. Smith

发明人： Chen Xu ,  Gary S. Silverman ,  Roman Y. Korotkov ,  Robert G. Smith

IPC分类号： B32B27/06 ,  B05D3/06

CPC分类号： H01L21/0262 ,  C23C16/407 ,  C23C16/482 ,  G02B5/0891 ,  G02B5/208 ,  H01L21/02422 ,  H01L21/02554 ,  H01L21/02573 ,  H01L31/0392 ,  H01L31/1884 ,  Y02E10/50

摘要： The invention provides a method of forming a layer on a polymer substrate comprises a polymer substrate with at least one precursor, and applying ultraviolet light to decompose the at least one precursor and deposit a layer onto the polymer substrate. Also provided is a doped layer comprising zinc oxide deposited on a polymer substrate obtained by introducing at least one precursor comprising zinc and a dopant into a vessel containing a polymer substrate, and applying an ultraviolet light to decompose the at least one precursor and to deposit a layer comprising doped zinc oxide onto the polymer substrate.

摘要翻译： 本发明提供了一种在聚合物基材上形成层的方法，其包含具有至少一种前体的聚合物基材，并施加紫外光以分解至少一种前体并将一层沉积在聚合物基材上。 还提供了包含沉积在聚合物基底上的氧化锌的掺杂层，其通过将包含锌和掺杂剂的至少一种前体引入到含有聚合物基底的容器中，并施加紫外光以分解至少一种前体并沉积 层，其包含掺杂的氧化锌到聚合物基底上。

公开(公告)号：US20120162484A1

公开(公告)日：2012-06-28

申请号：US12930015

申请日：2010-12-22

申请人： Yaowu Mo ,  Chen Xu

发明人： Yaowu Mo ,  Chen Xu

IPC分类号： H04N5/217

CPC分类号： H04N5/3575 ,  H04N5/2176 ,  H04N5/365

摘要： A method of one aspect includes reading a reset level of an active pixel, and concurrently, reading a reset level of a reference pixel. The method also includes reading an image signal level of the active pixel, and concurrently, reading an image signal level of the reference pixel. A reduced noise image signal level of the active pixel is generated based on the reset levels and the image signal levels of the active and reference pixels. Other methods are disclosed as well as apparatus and systems.

摘要翻译： 一个方面的方法包括读取有源像素的复位电平，同时读取参考像素的复位电平。 该方法还包括读取有源像素的图像信号电平，同时读取参考像素的图像信号电平。 基于有效和参考像素的复位电平和图像信号电平，生成有源像素的降低噪声图像信号电平。 公开了其它方法以及装置和系统。

公开(公告)号：US08085321B2

公开(公告)日：2011-12-27

申请号：US12222864

申请日：2008-08-18

申请人： Chen Xu ,  Parker Altice

发明人： Chen Xu ,  Parker Altice

IPC分类号： H04N5/217 ,  H01L27/00 ,  H01L29/66

CPC分类号： H04N5/3745 ,  H01L27/14609 ,  H04N5/359 ,  H04N5/361 ,  H04N5/363 ,  H04N5/374

摘要： An apparatus for and a method of operating an array of pixels of an image sensor, where each pixel includes at least a photosensor, an associated storage device and a floating diffusion region and the array of pixels is configured in a plurality of rows and columns. The photosensors associated with the pixels are reset and charges are accumulated in the photosensor. The accumulated charges are then globally transferred to storage devices associated with the pixels. A rolling double reset is used to reduce the deleterious effects on the accumulated charges stored in the storage devices. The accumulated charges stored in the storage devices are transferred to floating diffusion regions associated with the pixels and the charges residing in the floating diffusion region are read out. In a second embodiment the storage device is eliminated and the rolling double reset is used to reduce the deleterious effects on the accumulated charges stored in the floating diffusion region.

摘要翻译： 一种用于操作图像传感器的像素阵列的装置和方法，其中每个像素至少包括光传感器，相关联的存储装置和浮动扩散区域，并且像素阵列被配置成多个行和列。 与像素相关联的光电传感器被复位，并且电荷累积在光电传感器中。 然后将累积的费用全局转移到与像素相关联的存储设备。 使用滚动双重复位来减少存储在存储设备中的累积电荷的有害影响。 存储在存储装置中的累积电荷被转移到与像素相关联的浮动扩散区域，并且读出驻留在浮动扩散区域中的电荷。 在第二实施例中，消除了存储装置，并且使用滚动双重复位来减少对存储在浮动扩散区域中的累积电荷的有害影响。

公开(公告)号：US08018316B2

公开(公告)日：2011-09-13

申请号：US11747555

申请日：2007-05-11

申请人： Flavio Pardo ,  Maria E. Simon ,  Brijesh Vyas ,  Chen Xu

发明人： Flavio Pardo ,  Maria E. Simon ,  Brijesh Vyas ,  Chen Xu

IPC分类号： H01H71/18 ,  H01H61/00

CPC分类号： C23C18/32 ,  C23C18/1605 ,  C23C18/165 ,  C23C18/1651 ,  C23C18/1689 ,  C23C18/34 ,  C23C18/36

摘要： A method comprising forming a structural element 115 on a surface 620 of a layer 510 via an electroless plating of nickel or cobalt 130 onto the surface, the layer being rigidly fixed to an underlying substrate 110. The method also comprises etching away a portion of the layer such that a part of the structural element is able to move with respect to the substrate.

摘要翻译： 一种方法包括在层510的表面620上经由镍或钴130的无电镀层在表面上形成结构元件115，所述层刚性地固定到下面的基底110上。该方法还包括蚀刻掉部分 使得结构元件的一部分能够相对于基板移动。

公开(公告)号：US07991242B2

公开(公告)日：2011-08-02

申请号：US11431627

申请日：2006-05-11

申请人： Luc Perron ,  Michel R. Bouchard ,  Chen Xu ,  Sébastien Roy ,  Alain Bergeron ,  Eric Bergeron

发明人： Luc Perron ,  Michel R. Bouchard ,  Chen Xu ,  Sébastien Roy ,  Alain Bergeron ,  Eric Bergeron

IPC分类号： G06K9/40 ,  G06K9/00

CPC分类号： G06K9/746 ,  G06K9/28 ,  G06K9/3241 ,  G06K2209/09

摘要： A method and an apparatus suitable for screening a receptacle are provided. An image signal conveying an input image related to contents of the receptacle is received, the image signal having been produced by a device that is characterized by introducing distortion into the input image. A distortion correction process is applied to the image signal to remove at least part of the distortion from the input image, thereby to generate a corrected image signal conveying at least one corrected image. The corrected image signal is processed in combination with a plurality of data elements associated with a plurality of target objects in an attempt to detect a presence of at least one of the target objects in the receptacle. A detection signal is generated in response to detection of the presence of at least one target object in the receptacle.

摘要翻译： 提供了一种适于屏蔽插座的方法和装置。 接收到传送与插座的内容相关的输入图像的图像信号，图像信号已经由特征在于将失真引入到输入图像中的装置产生。 对图像信号应用失真校正处理以从输入图像中去除至少一部分失真，从而产生传送至少一个校正图像的校正图像信号。 校正图像信号与与多个目标对象相关联的多个数据元素组合处理，以试图检测存储器中至少一个目标对象的存在。 响应于检测到容器中至少一个目标物体的存在而产生检测信号。

公开(公告)号：US07920401B2

公开(公告)日：2011-04-05

申请号：US12545892

申请日：2009-08-24

申请人： Chen Xu ,  Thomas W. Voshell ,  Karl Holtzclaw

发明人： Chen Xu ,  Thomas W. Voshell ,  Karl Holtzclaw

IPC分类号： G11C17/00

CPC分类号： G11C17/16 ,  G11C17/18

摘要： Disclosed are apparatus, system and methods of programming and readout of a one-time programmable memory device having an array of memory cells, where the cells include an anti-fuse element and an in-cell amplifier transistor. Circuitry configured for programming and correlated double sampling readout of the cells is also disclosed.

摘要翻译： 公开了具有存储器单元阵列的一次性可编程存储器件的编程和读出的装置，系统和方法，其中单元包括反熔丝元件和单元内放大器晶体管。 还公开了配置用于单元的编程和相关双采样读出的电路。

公开(公告)号：US20100219342A1

公开(公告)日：2010-09-02

申请号：US12719562

申请日：2010-03-08

申请人： Chen Xu ,  Gennadiy Agranov ,  Igor Karasev

发明人： Chen Xu ,  Gennadiy Agranov ,  Igor Karasev

IPC分类号： H01L31/101 ,  H01L31/0232 ,  H01L31/09 ,  G01J5/22

CPC分类号： H04N5/378 ,  H04N5/3594 ,  H04N5/3745

摘要： Apparatus, systems, and methods are described to assist in reducing dark current in an active pixel sensor. In various embodiments, a potential barrier arrangement is configured to block the flow of charge carriers generated outside a photosensitive region. In various embodiments, a potential well-potential barrier arrangement is formed to direct charge carriers away from the photosensitive region during an integration time.