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公开(公告)号：US20150360223A1
公开(公告)日：2015-12-17
申请号：US14731491
申请日：2015-06-05
申请人： Enplas Corporation
发明人： Koichi ONO , Ken KITAMOTO
IPC分类号： B01L3/00
CPC分类号： B01L3/502715 , B01L3/502707 , B01L2200/0689 , B01L2200/12 , B01L2300/0645 , B01L2300/0816 , B01L2300/0887 , B01L2300/123 , B01L2300/16 , B01L2300/18 , B01L2300/1827 , B01L2400/0406
摘要： A fluid handling device includes a substrate, a film and a conductive layer. The substrate includes a through hole or a recess. The film includes first, second and third regions. The conductive layer is disposed on one surface of the film across the first, second and third regions. The first region of the film is bonded to one surface of the substrate such that one of openings of the through hole or an opening of the recess is closed to form a housing part, and that a part of the conductive layer is exposed to the inside of the housing part. The second region of the film is bent such that the conductive layer is located on an outside. The third region of the film is bonded to the first region of the film such that the conductive layer is exposed to the exterior.
摘要翻译： 流体处理装置包括基板，膜和导电层。 基板包括通孔或凹槽。 这部电影包括第一，第二和第三个地区。 导电层设置在膜的跨越第一，第二和第三区域的一个表面上。 膜的第一区域被粘合到基板的一个表面上，使得通孔的开口或凹部的开口中的一个闭合以形成壳体部分，并且导电层的一部分暴露于内部 的房屋部分。 薄膜的第二区域弯曲，使得导电层位于外部。 膜的第三区域被粘合到膜的第一区域，使得导电层暴露于外部。
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公开(公告)号：US20170173583A1
公开(公告)日：2017-06-22
申请号：US15117030
申请日：2015-02-10
申请人： Enplas Corporation
发明人： Ken KITAMOTO
IPC分类号： B01L3/00
CPC分类号： B01L3/502738 , B01L3/502715 , B01L3/502723 , B01L3/50273 , B01L2200/0684 , B01L2300/0816 , B01L2300/0848 , B01L2300/0887 , B01L2300/14 , B01L2400/0481 , B01L2400/0638 , F16K99/0015 , F16K99/0059
摘要： This liquid handling device is provided with a first chip that comprises a first substrate, a first film, a first flow path, a second flow path and a partition wall. A diaphragm portion of the first film is over the first flow path, the second flow path and the partition wall, and the center thereof is arranged over the first flow path. The first chip comprises a discharge hole or a discharge flow path which, in the liquid flow direction in the first flow path, opens into the first flow path between the partition wall and the center of the diaphragm and allows communication between the inside and outside of the first flow path.
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公开(公告)号：US20230294979A1
公开(公告)日：2023-09-21
申请号：US17695889
申请日：2022-03-16
申请人： Enplas Corporation
发明人： Ken KITAMOTO , Ryoya NAKAMURA
IPC分类号： B81C1/00
CPC分类号： B81C1/00071 , B81C2201/034
摘要： A manufacturing method capable of manufacturing a laminate including a substrate having a recess and a film with a high yield is provided. The method of manufacturing a laminate of the present invention includes: preparing a substrate having a recess; disposing a film on the substrate so as to cover the recess; and obtaining a laminate by thermocompression bonding between the film and the substrate by pressing the film and the substrate with a first elastic body and a second elastic body in a state in which the substrate on which the film is disposed is disposed between the first elastic body and the second elastic body such that the film is on the first elastic body side, in which the first elastic body is harder than the second elastic body.
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公开(公告)号：US20200024123A1
公开(公告)日：2020-01-23
申请号：US16499335
申请日：2018-03-09
申请人： Enplas Corporation
发明人： Ken KITAMOTO , Takumi YAMAUCHI
摘要： This liquid handling apparatus has a single introduction part that opens on a first surface side of a substrate and is for introducing a liquid, a plurality of discharge parts that open on the first surface side of the substrate and are for discharging the liquid that has been introduced through the single introduction part, a flow path for connecting the single introduction part and the plurality of discharge parts within the substrate, and a plurality of outflow prevention parts that are disposed so as to surround the openings of the plurality of discharge parts and are for using the surface tension of the liquid to check the progress of the outflow of the liquid from the discharge parts. For each opening part, there are two or more outflow prevention parts disposed so as to surround the opening part.
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公开(公告)号：US20170059484A1
公开(公告)日：2017-03-02
申请号：US15120025
申请日：2015-02-16
申请人： Enplas Corporation
发明人： Ken KITAMOTO , Koichi ONO
CPC分类号： G01N21/645 , G01N21/05 , G01N21/6428 , G01N33/02 , G01N2021/6439 , G01N2021/6482 , G01N2021/6484
摘要： This detection device is provided with: a chip including a detection region for detecting a substance to be detected; a light source which emits excitation light; a detector for detecting the fluorescence emitted from a fluorescent substance which labels the substance to be detected, and which is excited by the excitation light; and an optical fiber which includes a core, and a cladding covering the outer peripheral surface of the core, guides, to the detection region, the excitation light emitted from the light source, and guides, to the detector, the fluorescence emitted from the fluorescent substance. The optical fiber is fixed to the chip directly or via a connector. The excitation light emitted from the light source is guided within the core, and reaches the detection region of the chip. The fluorescence emitted from the fluorescent substance is guided within the core and the cladding, and reaches the detector.
摘要翻译： 该检测装置设置有：包括用于检测待检测物质的检测区域的芯片; 发射激发光的光源; 用于检测从被检测物质标记出被激发光激发的荧光物质发出的荧光的检测器; 并且包括芯的光纤和覆盖芯的外周表面的包层将从光源发射的激发光引导到检测区域，并将从荧光发射的荧光引导到检测器 物质。 光纤直接或通过连接器固定在芯片上。 从光源发射的激发光在芯内引导，到达芯片的检测区域。 从荧光物质发射的荧光在芯和包层内引导，并到达检测器。
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公开(公告)号：US20150343441A1
公开(公告)日：2015-12-03
申请号：US14722604
申请日：2015-05-27
申请人： Enplas Corporation
发明人： Koichi ONO , Ken KITAMOTO
IPC分类号： B01L3/00
CPC分类号： B01L3/502707 , B01L3/502715 , B01L3/50273 , B01L2200/0689 , B01L2200/12 , B01L2300/0645 , B01L2300/0816 , B01L2300/0887 , B01L2300/123 , B01L2300/14 , B01L2300/1827
摘要： A fluid handling device includes a substrate, a film, and a conductive layer. The substrate includes a first through-hole, and a second through-hole. The conductive layer is disposed on one surface of the film to extend in a first area, a second area and a third area of the film. The substrate includes a first surface and a second surface facing away from the first surface. The first area is bonded to the first surface of the substrate such that a housing part is formed by closing one opening of the first through-hole, and such that a part of the conductive layer is exposed to the inside of the housing part. The second area is disposed inside the second through-hole, and the third area is bonded to the second surface of the substrate such that a part of the conductive layer is exposed to the outside.
摘要翻译： 流体处理装置包括基板，膜和导电层。 基板包括第一通孔和第二通孔。 导电层设置在膜的一个表面上，以在膜的第一区域，第二区域和第三区域中延伸。 基板包括第一表面和背离第一表面的第二表面。 第一区域结合到基板的第一表面，使得通过闭合第一通孔的一个开口形成壳体部分，并且使得导电层的一部分暴露于壳体部分的内部。 第二区域设置在第二通孔的内部，并且第三区域结合到基板的第二表面，使得导电层的一部分暴露于外部。
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公开(公告)号：US20220055028A1
公开(公告)日：2022-02-24
申请号：US17298988
申请日：2019-11-20
申请人： Enplas Corporation
发明人： Ken KITAMOTO , Koji MURAKI , Yuya OSHIMA
摘要： The present invention addresses the problem of providing a fluid handling system that is capable of injecting a fluid into a desired chip or the like without using a large-scale device. In order to resolve the problem, this fluid handling system has a reservoir, a flow path chip, and a cap, one end of which is fitted to the internal opening of the reservoir and the other end of which is connected to an introduction port of the flow path chip, the cap having a through-hole that links the one end and the other end. In this fluid handling system, a protruding part provided to the flow path chip is fitted into the through-hole at the other end of the cap and restricts blocking of the through-hole when a fluid moves inside the through-hole of the cap.
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公开(公告)号：US20190170645A1
公开(公告)日：2019-06-06
申请号：US16268663
申请日：2019-02-06
申请人： Enplas Corporation
发明人： Ken KITAMOTO , Koichi ONO
CPC分类号： G01N21/645 , G01N21/05 , G01N21/6428 , G01N33/02 , G01N2021/6439 , G01N2021/6482 , G01N2021/6484
摘要： This detection device is provided with: a chip including a detection region for detecting a substance to be detected; a light source which emits excitation light; a detector for detecting the fluorescence emitted from a fluorescent substance which labels the substance to be detected, and which is excited by the excitation light; and an optical fiber which includes a core, and a cladding covering the outer peripheral surface of the core, guides, to the detection region, the excitation light emitted from the light source, and guides, to the detector, the fluorescence emitted from the fluorescent substance. The optical fiber is fixed to the chip directly or via a connector. The excitation light emitted from the light source is guided within the core, and reaches the detection region of the chip. The fluorescence emitted from the fluorescent substance is guided within the core and the cladding, and reaches the detector.
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公开(公告)号：US20170314704A1
公开(公告)日：2017-11-02
申请号：US15526498
申请日：2015-10-29
申请人： Enplas Corporation
发明人： Ken KITAMOTO , Koichi ONO
摘要： A liquid handling device has an accommodation part for accommodating a liquid, two or more flow paths each opening to a lower part of a side wall surface of the accommodation part, and a liquid movement suppression part that is disposed in the lower part of the side wall between the openings of two of the flow paths that are adjacent to each other and slows or stops the movement of the liquid along the corner formed by the lower surface of the accommodation part and the side wall surface.
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公开(公告)号：US20150021501A1
公开(公告)日：2015-01-22
申请号：US14331249
申请日：2014-07-15
申请人： Enplas Corporation
发明人： Koichi ONO , Ken KITAMOTO
IPC分类号： F16K99/00 , F16K31/126
CPC分类号： F16K99/0059 , B01L3/502738 , B01L2300/0864 , B01L2300/0887 , B01L2400/049 , B01L2400/0655 , F16K99/0015 , F16K2099/008 , F16K2099/0084
摘要： A micro fluid chip includes a first chip and a second chip. The first chip includes a first substrate having a fluid channel and a partition wall, and a first film made of resin. The second chip includes a second substrate having a recess, and a second film made of elastomer. The second film has an elastic modulus higher than that of the first film. The first chip and the second chip are stacked in such a manner that the partition wall and the recess face each other with the first film and the second film therebetween. By setting the inner side of the recess to a negative pressure, a gap is formed between the first film and the partition wall, and thus a fluid channel is opened.
摘要翻译： 微流体芯片包括第一芯片和第二芯片。 第一芯片包括具有流体通道和分隔壁的第一基板和由树脂制成的第一薄膜。 第二芯片包括具有凹部的第二基板和由弹性体制成的第二薄膜。 第二膜具有比第一膜高的弹性模量。 第一芯片和第二芯片以这样的方式堆叠，使得分隔壁和凹部彼此面对，其中第一膜和第二膜彼此面对。 通过将凹部的内侧设定为负压，在第一膜和分隔壁之间形成间隙，从而打开流体流路。
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