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1.发明申请公开(公告)号：US20050250768A1
公开(公告)日：2005-11-10
申请号：US10921965
申请日：2004-08-20
申请人： James Link , Gang Liu , ZhongHua Pei , Tom Geldern , Martin Winn , Zhili Xin , Steven Boyd , Gui-Dong Zhu , Jennifer Freeman , Indrani Gunawardana , Michael Staeger , Hwan-Soo Jae , John Lynch , Sheldon Wang
发明人： James Link , Gang Liu , ZhongHua Pei , Tom Geldern , Martin Winn , Zhili Xin , Steven Boyd , Gui-Dong Zhu , Jennifer Freeman , Indrani Gunawardana , Michael Staeger , Hwan-Soo Jae , John Lynch , Sheldon Wang
IPC分类号： A61K31/454 , A61K31/495 , A61K31/496 , A61K31/537 , A61K31/54 , C07C323/62 , C07D205/04 , C07D207/09 , C07D207/14 , C07D207/26 , C07D207/27 , C07D209/08 , C07D211/20 , C07D211/46 , C07D211/60 , C07D213/40 , C07D213/81 , C07D217/06 , C07D241/04 , C07D295/185 , C07D295/26 , C07D401/04 , C07D521/00
CPC分类号： C07D207/27 , A61K31/454 , A61K31/495 , A61K31/496 , A61K31/537 , A61K31/54 , C07C323/62 , C07C2601/02 , C07D205/04 , C07D207/09 , C07D207/14 , C07D209/08 , C07D211/20 , C07D211/46 , C07D211/60 , C07D213/40 , C07D213/81 , C07D217/06 , C07D231/12 , C07D233/56 , C07D241/04 , C07D249/08 , C07D295/185 , C07D295/26 , C07D401/04
摘要： The present invention relates to novel cinnamide compounds that are useful for treating inflammatory and immune diseases, to pharmaceutical compositions containing these compounds, and to methods of inhibiting inflammation or suppressing immune response in a mammal.
摘要翻译： 本发明涉及可用于治疗炎症和免疫疾病的新颖的肉桂酰胺化合物，含有这些化合物的药物组合物，以及抑制哺乳动物炎症或抑制免疫反应的方法。
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2.发明申请Antagonists of melanin concentrating hormone effects on the melanin concentrating hormone receptor 审中-公开黑色素浓缩激素对黑色素浓缩激素受体的拮抗作用公开(公告)号：US20050187387A1
公开(公告)日：2005-08-25
申请号：US10787694
申请日：2004-02-25
申请人： John Lynch , Christine Collins , Jennifer Freeman , Ju Gao , Rajesh Iyengar , Andrew Judd , Philip Kym , Mathew Mulhern , Hing Sham , Andrew Souers , Gang Zhao
发明人： John Lynch , Christine Collins , Jennifer Freeman , Ju Gao , Rajesh Iyengar , Andrew Judd , Philip Kym , Mathew Mulhern , Hing Sham , Andrew Souers , Gang Zhao
IPC分类号： B32B27/02 , C07D401/12 , C07D405/12 , C07D405/14 , C07D413/14 , C07D417/14
CPC分类号： C07D405/12 , C07D401/12 , C07D405/14 , C07D413/14 , C07D417/14
摘要： The present invention is directed to compounds of formula (I), which antagonize of the effects of melanin-concentrating hormone (MCH) through the melanin concentrating hormone receptor which is useful for the prevention or treatment of eating disorders, weight gain, obesity, abnormalities in reproduction and sexual behavior, thyroid hormone secretion, diuresis and water/electrolyte homeostasis, sensory processing, memory, sleeping, arousal, anxiety, depression, seizures, neurodegeneration and psychiatric disorders.
摘要翻译： 本发明涉及通过黑色素浓缩激素受体拮抗黑色素浓缩激素（MCH）的作用的式（I）化合物，其可用于预防或治疗进食障碍，体重增加，肥胖症，异常 生殖和性行为，甲状腺激素分泌，利尿和水/电解质体内平衡，感觉加工，记忆，睡眠，觉醒，焦虑，抑郁，癫痫发作，神经变性和精神疾病。
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公开(公告)号：US20060120213A1
公开(公告)日：2006-06-08
申请号：US11283525
申请日：2005-11-17
申请人： Anna Tonkovich , Jennifer Freeman , Bin Yang , Laura Silva , Richard Long , Paul Neagle , Barry Yang , Thomas Yuschak , Eric Daymo , Dongming Qiu , Kristina Pagnotto , Michael Marchiando , Amanda Glass , David Kuhlmann , Jeffrey Marco , Harley Freeman , William Rogers
发明人： Anna Tonkovich , Jennifer Freeman , Bin Yang , Laura Silva , Richard Long , Paul Neagle , Barry Yang , Thomas Yuschak , Eric Daymo , Dongming Qiu , Kristina Pagnotto , Michael Marchiando , Amanda Glass , David Kuhlmann , Jeffrey Marco , Harley Freeman , William Rogers
CPC分类号： B01F5/0057 , B01F3/0807 , B01F3/0815 , B01F5/0475 , B01F5/0476 , B01F5/0485 , B01F5/061 , B01F7/00758 , B01F13/0059 , B01F2005/0623 , B01F2005/0636 , B01F2015/062 , B01J19/0093 , B01J2219/00756 , B01J2219/00783 , B01J2219/00822 , B01J2219/00826 , B01J2219/00831 , B01J2219/00833 , B01J2219/00835 , B01J2219/00837 , B01J2219/00844 , B01J2219/0086 , B01J2219/00873 , B01J2219/00889 , F28D7/0008 , F28F2260/02
摘要： The disclosed invention relates to a process for treating or making an emulsion in a microchannel. The emulsion comprises a first liquid and a second liquid, the first liquid forming a continuous phase, the second liquid forming droplets dispersed in the continuous phase.
摘要翻译： 所公开的本发明涉及在微通道中处理或制备乳液的方法。 乳液包括第一液体和第二液体，第一液体形成连续相，第二液体形成液滴分散在连续相中。
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公开(公告)号：US20150361104A1
公开(公告)日：2015-12-17
申请号：US14765152
申请日：2014-01-31
申请人： Tsutomu AKAMA , Eric EASOM , Yvonne FREUND , Jacob J. PLATTNER , Jessica SLIGAR , Daitao CHEN , Jennifer FREEMAN , Joe PERALES , ANACOR PHARMACEUTICALS, INC.
发明人： Tsutomu AKAMA , Eric Easom , Yvonne Freund , Jacob J. Plattner , Jessica Sligar , Daitao Chen , Jennifer Freeman , Joe Perales
摘要： This invention provides, among other things, novel compounds useful for treating protozoal infections, pharmaceutical compositions containing such compounds, as well as combinations of these compounds with at least one additional therapeutically effective agent.
摘要翻译： 本发明尤其提供了可用于治疗原生动物感染的新化合物，含有这些化合物的药物组合物，以及这些化合物与至少一种另外的治疗有效药物的组合。
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公开(公告)号：US20080064717A1
公开(公告)日：2008-03-13
申请号：US11749952
申请日：2007-05-17
申请人： Rajesh Iyengar , Gang Zhao , Jennifer Freeman , Ju Gao , Andrew Judd , Philip Kym , John Lynch , Mathew Mulhern , Andrew Souers
发明人： Rajesh Iyengar , Gang Zhao , Jennifer Freeman , Ju Gao , Andrew Judd , Philip Kym , John Lynch , Mathew Mulhern , Andrew Souers
IPC分类号： A61K31/4402 , A61K31/17 , A61K31/19 , A61P3/00 , C07C61/06 , C07D471/04 , C07D213/46 , C07C275/28 , A61P1/16 , A61K31/4375
CPC分类号： C07C335/22 , C07C229/46 , C07C275/30 , C07C275/32 , C07C275/38 , C07C279/28 , C07C2601/08 , C07C2601/14 , C07D213/55 , C07D213/75 , C07D277/30 , C07D333/22 , C07D333/36 , C07D401/04 , C07D401/12 , C07D409/12 , C07D409/14
摘要： The present invention relates to compounds of formula (I): wherein R1, R3, X, Q, Z, A, 9, m, and n are defined herein Pharmaceutical compositions and methods for treating DGAT-1 related diseases or conditions are also disclosed.
摘要翻译： 本发明涉及式（I）化合物：其中R 1，R 3，X，Q，Z，A，9，m和n如本文所定义 还公开了治疗DGAT-1相关疾病或病症的药物组合物和方法。
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6.发明申请公开(公告)号：US20050209274A1
公开(公告)日：2005-09-22
申请号：US11065918
申请日：2005-02-25
申请人： John Lynch , Christine Collins , Jennifer Freeman , Ju Gao , Rajesh Iyengar , Andrew Judd , Philip Kym , Mathew Mulhern , Hing Sham , Andrew Souers , Gang Zhao , Dariusz Wodka
发明人： John Lynch , Christine Collins , Jennifer Freeman , Ju Gao , Rajesh Iyengar , Andrew Judd , Philip Kym , Mathew Mulhern , Hing Sham , Andrew Souers , Gang Zhao , Dariusz Wodka
IPC分类号： A61K31/452 , A61K31/4709 , C07D405/12 , C07D405/14 , C07D409/14 , C07D413/14 , C07D417/14 , C07D45/02
CPC分类号： C07D417/14 , C07D405/12 , C07D405/14 , C07D409/14 , C07D413/14
摘要： The present invention is directed to compounds of formula (I), which antagonize of the effects of melanin-concentrating hormone (MCH) through the melanin concentrating hormone receptor which is useful for the prevention or treatment of eating disorders, weight gain, obesity, abnormalities in reproduction and sexual behavior, thyroid hormone secretion, diuresis and water/electrolyte homeostasis, sensory processing, memory, sleeping, arousal, anxiety, depression, seizures, neurodegeneration and psychiatric disorders.
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