发明授权
- 专利标题： Ketoreductases and uses thereof
- 专利标题（中）： 酮还原酶及其用途
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申请号： US12881734申请日： 2010-09-14
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公开(公告)号： US08071347B2公开(公告)日： 2011-12-06
- 发明人: Charlene Ching , John M. Gruber , Gjalt W. Huisman , Emily Mundorff , Lisa M. Newman
- 申请人： Charlene Ching , John M. Gruber , Gjalt W. Huisman , Emily Mundorff , Lisa M. Newman
- 申请人地址： US CA Redwood City
- 专利权人： Codexis, Inc.
- 当前专利权人： Codexis, Inc.
- 当前专利权人地址： US CA Redwood City
- 主分类号： C12N9/04
- IPC分类号： C12N9/04 ; C12N1/20 ; C12N15/00 ; C12Q1/00 ; C12Q1/34 ; C12P21/04 ; C07H21/04
摘要：
The present disclosure provides engineered ketoreductase enzymes having improved properties as compared to a naturally occurring wild-type ketoreductase enzyme. Also provided are polynucleotides encoding the engineered ketoreductase enzymes, host cells capable of expressing the engineered ketoreductase enzymes, and methods of using the engineered ketoreductase enzymes to synthesize a variety of chiral compounds.
公开/授权文献
- US20110165670A1 Ketoreductases and Uses Thereof 公开/授权日：2011-07-07
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