Invention Grant
- Patent Title: Ketoreductases and uses thereof
- Patent Title (中): 酮还原酶及其用途
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Application No.: US12028780Application Date: 2008-02-08
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Publication No.: US07820421B2Publication Date: 2010-10-26
- Inventor: Charlene Ching , John M. Gruber , Gjalt W. Huisman , Emily Mundorff , Lisa M. Newman
- Applicant: Charlene Ching , John M. Gruber , Gjalt W. Huisman , Emily Mundorff , Lisa M. Newman
- Applicant Address: US CA Redwood City
- Assignee: Codexis, Inc.
- Current Assignee: Codexis, Inc.
- Current Assignee Address: US CA Redwood City
- Main IPC: C12N9/04
- IPC: C12N9/04 ; C12N1/20 ; C12N15/00 ; C12Q1/00 ; C12Q1/68 ; C12Q1/34 ; C12P21/04 ; C07H21/04
Abstract:
The present disclosure provides engineered ketoreductase enzymes having improved properties as compared to a naturally occurring wild-type ketoreductase enzyme. Also provided are polynucleotides encoding the engineered ketoreductase enzymes, host cells capable of expressing the engineered ketoreductase enzymes, and methods of using the engineered ketoreductase enzymes to synthesize a variety of chiral compounds.
Public/Granted literature
- US20080318295A1 Ketoreductases and Uses Thereof Public/Granted day:2008-12-25
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