公开(公告)号：US20230089555A1

公开(公告)日：2023-03-23

申请号：US17790846

申请日：2021-01-08

申请人： LG Chem, Ltd.

发明人： Yongwook Kim ,  Jaechol Lee ,  Hisayuki Kawamura ,  Shinji Shiraki ,  Tsukasa Owada ,  Ayato Arai ,  Hisahiro Sasabe ,  Junji Kido

IPC分类号： C07C211/54 ,  C07D209/84 ,  C07D219/02 ,  C07D471/04 ,  C07D265/38 ,  C07D279/30 ,  C07F7/08 ,  C07D241/46 ,  C07F5/02 ,  C07D223/14 ,  H01L51/00 ,  H01L51/50

摘要： The present invention is to provide a light emitting material, for an organic EL device, exhibiting higher light emitting efficiency, and particularly, to provide a blue light emitting material, wherein the light emitting material comprises a compound of the following General Formula (1): X is an aryl group including a tertiary amine structure, and Y is a phenyl group having an alkyl or aryl substituent at one ortho position.

公开(公告)号：US20210340107A1

公开(公告)日：2021-11-04

申请号：US17221358

申请日：2021-04-02

申请人： BIOGEN MA INC.

发明人： Brian Stuart Lucas ,  Edward Yin Shiang Lin ,  Andrew George Capacci ,  Zhili Xin ,  Istvan Enyedy ,  TeYu Chen ,  John H. Jones ,  Kurt D. van Vloten

IPC分类号： C07D217/04 ,  C07D217/08 ,  C07D217/20 ,  C07D217/22 ,  C07D223/14 ,  C07D311/74 ,  C07D401/04 ,  C07D401/06 ,  C07D405/04 ,  C07D405/06 ,  C07D413/06 ,  C07D498/04

摘要： Provided are compounds of Formula I, or pharmaceutically acceptable salts thereof, and methods for their use and production.

公开(公告)号：US10968181B2

公开(公告)日：2021-04-06

申请号：US16473667

申请日：2017-12-27

申请人： BIOGEN MA INC.

发明人： Brian Stuart Lucas ,  Edward Yin-Shiang Lin ,  Andrew George Capacci ,  Zhili Xin ,  Istvan Enyedy ,  TeYu Chen ,  John H. Jones ,  Kurt D. van Vloten

IPC分类号： C07D311/76 ,  C07D217/04 ,  C07D217/08 ,  C07D223/16 ,  C07D498/14 ,  A61K31/352 ,  A61K31/47 ,  C07D217/20 ,  C07D217/22 ,  C07D223/14 ,  C07D311/74 ,  C07D401/04 ,  C07D401/06 ,  C07D405/04 ,  C07D405/06 ,  C07D413/06 ,  C07D498/04

摘要： Provided are compounds of Formula I, or pharmaceutically acceptable salts thereof, and methods for their use and production.

公开(公告)号：US20210002231A1

公开(公告)日：2021-01-07

申请号：US16979353

申请日：2019-03-11

申请人： Centre National de la Recherche Scientifique ,  Université de Strasbourg ,  Vrije Universiteit Brussel

发明人： Frédéric Simonin ,  Armand Drieu la Rochelle ,  Frédéric Bihel ,  Steven Ballet

IPC分类号： C07D223/14 ,  A61K38/04

摘要： Molecules binding the mu opioid receptor (MOR) and the neuropeptide FF receptor (NPFFR), in particular molecules having a MOR agonist and NPFFR modulatory activity, and pharmaceutical compositions useful in the treatment of pain and/or hyperalgesia.

公开(公告)号：US10800730B2

公开(公告)日：2020-10-13

申请号：US16136830

申请日：2018-09-20

申请人： The Board of Trustees of the University of Illinois

发明人： Paul J. Hergenrother ,  Robert W. Huigens, III ,  Karen C. Morrison ,  Robert W. Hicklin, II ,  Timothy A. Flood, Jr.

IPC分类号： C07C69/757 ,  C07J21/00 ,  C07J69/00 ,  C07J71/00 ,  C07J73/00 ,  C07J75/00 ,  C07D401/14 ,  C07D311/94 ,  C07D313/06 ,  C07D223/14 ,  C07D401/04 ,  C07D471/04 ,  C07D471/08 ,  C07D493/08 ,  C07D513/04 ,  C07D519/00 ,  C07C59/205 ,  C07C62/32 ,  C07C62/38 ,  C07D303/10 ,  C07B37/06 ,  C07B37/08 ,  C07D307/93 ,  C07D313/08 ,  C07D405/06 ,  C07D405/12 ,  C07D413/06

摘要： The invention provides a novel, general, and facile strategy for the creation of small molecules with high structural and stereochemical complexity. Aspects of the methods include ring system distortion reactions that are systematically applied to rapidly convert readily available natural products to structurally complex compounds with diverse molecular architectures. Through evaluation of chemical properties including fraction of sp3 carbons, ClogP, and the number of stereogenic centers, these compounds are shown to be significantly more complex and diverse than those in standard screening collections. This approach is demonstrated with natural products (gibberellic acid, adrenosterone, and quinine) from three different structural classes, and methods are described for the application of this strategy to any suitable natural product.

公开(公告)号：US10730037B2

公开(公告)日：2020-08-04

申请号：US15780396

申请日：2016-12-26

申请人： TOYO GOSEI CO., LTD.

发明人： Takashi Miyazawa ,  Ken-ichi Sakaguchi

IPC分类号： B01J31/06 ,  C07B53/00 ,  C07C249/02 ,  C08F212/14 ,  C07D317/28 ,  B01J31/02 ,  C07D401/06 ,  C07D519/00 ,  B01J38/00 ,  C07D223/14 ,  C07B61/00 ,  C08F212/36 ,  C08F8/00 ,  C07D471/10 ,  C07D487/10 ,  C07C251/24

摘要： Synthesis of organic compounds that has chirality is an important technique in the fields of pharmaceuticals, agrichemicals, health foods and the like. However, raw materials of a catalyst used for the synthesis of such compounds are expensive, and the synthesis needs many steps, so that it is difficult to reduce the cost. Linking a catalyst center to a polymer chain or a resin through an organic group enables to use the catalyst repeatedly and produce a chiral compound at low cost.

公开(公告)号：US10424744B2

公开(公告)日：2019-09-24

申请号：US15416576

申请日：2017-01-26

申请人： Nichem Fine Technology Co., Ltd.

发明人： Liang-Di Liao ,  Shwu-Ju Shieh ,  Chi-Chung Chen

IPC分类号： H01L51/50 ,  H01L51/00 ,  C07F15/00 ,  C09K11/06 ,  C07C255/51 ,  C07D213/06 ,  C07D213/22 ,  C07D213/57 ,  C07D235/18 ,  C07D239/26 ,  C07D239/74 ,  C07D251/24 ,  C07C211/61 ,  C07D223/14 ,  C07D307/91 ,  C07D313/06 ,  C07D213/38 ,  H01L51/42

摘要： A novel compound is disclosed, which is represented by the following Formula (I): wherein Ar1, Ar2, Ar3, Ar4, L, Q, G, n1, n2, m1, m2 and q represent the same as defined in the specification. In addition, an organic electronic device is also disclosed, and an organic layer therein comprises the novel compound of the present invention.

公开(公告)号：US09793496B2

公开(公告)日：2017-10-17

申请号：US14731011

申请日：2015-06-04

申请人： SAMSUNG DISPLAY CO., LTD.

发明人： Dongwoo Shin ,  Seulong Kim ,  Younsun Kim ,  Jungsub Lee ,  Naoyuki Ito

IPC分类号： C07D223/14 ,  C07D401/04 ,  C07D403/04 ,  H01L51/00 ,  C09K11/06 ,  C07D401/02 ,  C09K11/02 ,  H05B33/14 ,  H01L51/50

CPC分类号： H01L51/0072 ,  C07D223/14 ,  C07D401/02 ,  C07D403/04 ,  C09B1/00 ,  C09B57/00 ,  C09B57/008 ,  C09B57/10 ,  C09K11/025 ,  C09K11/06 ,  C09K2211/1007 ,  C09K2211/1011 ,  C09K2211/1029 ,  C09K2211/1044 ,  H01L51/0054 ,  H01L51/0058 ,  H01L51/006 ,  H01L51/0067 ,  H01L51/0085 ,  H01L51/5008 ,  H01L51/5012 ,  H01L51/5016 ,  H01L51/5056 ,  H01L51/5072 ,  H01L51/5088 ,  H01L51/5092 ,  H01L51/5096 ,  H05B33/14

摘要： A condensed cyclic compound and an organic light-emitting device, the compound being represented by Formula 1: (A1)a1-(L1)b1-(A2)a2   wherein, in Formula 1, A1 is a group represented by Formula 2-1, below, a1 is 1, 2, or 3, and, when a1 is 2 or greater, two or more A1s are identical to or different from each other, A2 is a group represented by Formula 2-2, below, a2 is 1, 2, or 3, and, when a2 is 2 or greater, two or more A2s are identical to or different from each other,

公开(公告)号：US09755161B2

公开(公告)日：2017-09-05

申请号：US14919944

申请日：2015-10-22

申请人： LG Display Co., Ltd.

发明人： DoHan Kim ,  JungKeun Kim ,  Hyoseok Kim ,  Min Yun ,  SeungHee Yoon

IPC分类号： H01L51/54 ,  H01L51/00 ,  C07D223/14 ,  C07D403/04 ,  C07D409/10 ,  C09K11/06 ,  C07D223/32 ,  C09K11/02 ,  H01L51/50

CPC分类号： H01L51/0072 ,  C07D223/14 ,  C07D223/32 ,  C07D403/04 ,  C07D409/10 ,  C09K11/025 ,  C09K11/06 ,  C09K2211/1007 ,  C09K2211/1011 ,  C09K2211/1029 ,  C09K2211/1059 ,  C09K2211/1092 ,  C09K2211/185 ,  H01L51/0052 ,  H01L51/0056 ,  H01L51/0058 ,  H01L51/0067 ,  H01L51/0074 ,  H01L51/0085 ,  H01L51/5016 ,  H01L51/5072

摘要： An organic light emitting display device is disclosed. The organic light emitting display device comprises an anode, an organic layer over the anode, and a cathode over the organic layer. The organic layer may include a heterocyclic compound. Alternatively, the organic layer may include a spirobisfluorene compound with hole transfer properties and a material with electron transfer properties.

公开(公告)号：US09695112B2

公开(公告)日：2017-07-04

申请号：US14890887

申请日：2014-03-27

申请人： HAMARI CHEMICALS, LTD.

发明人： Hiroki Moriwaki ,  Aki Kawashima ,  Ryosuke Takeda ,  Akie Kawamura ,  Vadim A. Soloshonok

IPC分类号： C07D213/55 ,  C07C227/32 ,  C07D223/14 ,  C07B53/00 ,  C07C319/20 ,  C07C231/18 ,  C07F15/04

CPC分类号： C07C227/32 ,  C07B53/00 ,  C07B2200/07 ,  C07C231/18 ,  C07C319/20 ,  C07C2601/02 ,  C07D213/55 ,  C07D223/14 ,  C07F15/045 ,  C07C229/22 ,  C07C229/24 ,  C07C229/30 ,  C07C229/36 ,  C07C229/48 ,  C07C237/08 ,  C07C323/58

摘要： Objects of the present invention are to provide an industrially applicable method for producing an optically active α-amino acid in high yield and in a highly enantioselective manner, to provide a simple production method of an optically active α,α-disubstituted α-amino acid, and to provide an intermediate useful for the above production methods of an optically active α-amino acid and an optically active α,α-disubstituted α-amino acid.The present invention provides a production method of an optically active α-amino acid or a salt thereof, the production method comprising introducing a substituent into the α carbon in the α-amino acid moiety of a metal complex represented by the following Formula (1): by an alkylation reaction, an aldol reaction, the Michael reaction, or the Mannich reaction, and releasing an optically pure α-amino acid enantiomer or a salt thereof by acid decomposition of the metal complex.