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公开(公告)号:US20240158232A1
公开(公告)日:2024-05-16
申请号:US18515193
申请日:2023-11-20
发明人: Gilly Regev , Christopher C. Miller
CPC分类号: C01B21/24 , A61K47/02 , A61K47/12 , C01P2006/12 , C01P2006/14
摘要: Nitric oxide (NO) generating compositions can include a nitrite component, an acidifying component, and a support material configured to carry one of the nitrite component and the acidifying agent. In some examples, the support material can minimize NO generation prior to addition of an activating amount of a suitable solvent.
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公开(公告)号:US20240075240A1
公开(公告)日:2024-03-07
申请号:US18455177
申请日:2023-08-24
申请人: VERO Biotech Inc.
发明人: Barry N. GELLMAN , Eddie TAJUDEEN , Lucas GAMERO , Joshua HOPKINS , Edward E.A. BROMBERG , Ryan DENTON , Bryan J. JOHNSON , David FINE
CPC分类号: A61M16/12 , C01B21/24 , A61M2016/0027 , A61M2202/0275
摘要: A nitric oxide delivery system can include a cassette which is a single use disposable component used to store liquid N2O4 activate upon operator demand, convert N2O4 to NO2 via a heating element(s) controlled by a console to deliver NO2 at a controlled flow rate, direct concentrated NO2 to a contained pair of conversion cartridges and exhaust NO gas to the console for delivery to the patient.
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公开(公告)号:US11827989B2
公开(公告)日:2023-11-28
申请号:US17837416
申请日:2022-06-10
申请人: Third Pole, Inc.
摘要: System and methods for providing nitric oxide can include at least one pair of electrodes configured to generate a product gas containing nitric oxide from a flow of a reactant gas, and at least one controller configured to regulate an amount of nitric oxide in the product gas generated by the at least one pair of electrodes using one or more parameters as an input to the controller. One or more sensors are configured to collect information relating to at least one of patient information, the reactant gas, the product gas, and an inspiratory gas into which at least a portion of the product gas flows, the sensors configured to communicate the information to the controller to be used as the one or more parameters. The patient information includes information relating to a methemoglobin (MetHg) measurement collected from a MetHg sensor.
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公开(公告)号:US11820655B2
公开(公告)日:2023-11-21
申请号:US16612135
申请日:2018-05-11
CPC分类号: C01B21/24 , B01J19/121 , B01J19/123 , B01J19/125 , B01J19/126 , B01J19/127 , B01J19/128 , B01J19/129 , B01J19/2405 , B01J19/26 , B01J2219/0869 , B01J2219/0875 , B01J2219/0877 , B01J2219/185 , B01J2219/1943 , B01J2219/1946
摘要: The present invention provides a method of controlling back reactions or recombination reactions of product molecules formed in a dissociation reaction of reactant molecules of a fluid sample, in a reaction chamber. The method comprises introducing the fluid sample into the reaction chamber through one or more inlets, initiating the dissociation reaction of the reactant molecules of the fluid sample in the reaction chamber to form the product molecules, creating a patterned flow of the fluid sample in the reaction chamber to reduce/minimize disordered and/or turbulent mixing of the reactant molecules and/or product molecules in the fluid sample, and conveying the fluid sample comprising the product molecules out from the reaction chamber through one or more outlets.
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公开(公告)号:US11511252B2
公开(公告)日:2022-11-29
申请号:US16590093
申请日:2019-10-01
申请人: VERO Biotech Inc.
摘要: A nitric oxide delivery system, which includes a gas bottle having nitrogen dioxide in air, converts nitrogen dioxide to nitric oxide and employs a surface-active material, such as silica gel, coated with an aqueous solution of antioxidant, such as ascorbic acid. A nitric oxide delivery system may be used to generate therapeutic gas including nitric oxide for use in delivering the therapeutic gas to a mammal.
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公开(公告)号:US11508230B2
公开(公告)日:2022-11-22
申请号:US15614525
申请日:2017-06-05
IPC分类号: G08B21/16 , G08B3/10 , G08B5/36 , G05B19/418 , G05B23/02 , F02D41/14 , G01N33/00 , B01D53/30 , C01B17/69 , C01B21/24 , C01B21/36 , C08K5/37
摘要: Systems and methods of preventing an event occurrence or mitigating effects of an event occurrence in an industrial facility are disclosed herein. In some embodiments, a first input is received from a first sensor and, based at least in part on the first input, an initial action is automatically generated. In response to the initial action, a second input is received from a second sensor and, based at least in part of the received first and second inputs, a likelihood of an event occurrence is determined. Based at least in part of the determined likelihood, a remedial action configured to prevent the occurrence of the event occurrence is automatically generated. In some embodiments, the remedial action is generated in real-time and can be directed to a process condition, environmental condition, or secondary source.
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公开(公告)号:US11285171B2
公开(公告)日:2022-03-29
申请号:US16975843
申请日:2019-03-01
申请人: Novan, Inc.
IPC分类号: A61K9/02 , A61K47/44 , C01B21/24 , A61K33/00 , A61K9/00 , A61K47/10 , A61K47/12 , A61K47/24 , A61K47/42 , C01B21/40
摘要: The present invention relates generally to suppositories that release nitric oxide, and methods of using the same. According to some embodiments of the present invention provided herein is a nitric oxide (NO) releasing suppository (e.g., vaginal suppositories) are described herein. Some embodiments are directed to compositions, kits, and/or methods for treating and/or preventing an infection (e.g., a viral infection). In some embodiments, a method of treating and/or preventing a viral infection in a subject in need thereof is provided.
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公开(公告)号:US20210121655A1
公开(公告)日:2021-04-29
申请号:US16988185
申请日:2020-08-07
申请人: VERO Biotech LLC
发明人: Barry N. GELLMAN , Eddie TAJUDEEN , Lucas GAMERO , Joshua HOPKINS , Edward E.A. BROMBERG , Ryan DENTON , Bryan J. JOHNSON , David FINE
摘要: A nitric oxide delivery system can include a cassette which is a single use disposable component used to store liquid N2O4 activate upon operator demand, convert N2O4 to NO2 via a heating element(s) controlled by a console to deliver NO2 at a controlled flow rate, direct concentrated NO2 to a contained pair of conversion cartridges and exhaust NO gas to the console for delivery to the patient.
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公开(公告)号:US10723624B2
公开(公告)日:2020-07-28
申请号:US16208926
申请日:2018-12-04
摘要: Described herein is an improved conversion of nitrous oxide (N2O) present as a by-product in a chemical process to NOx which can be further converted to a useful compound or material, such as nitric acid.
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公开(公告)号:US10543336B2
公开(公告)日:2020-01-28
申请号:US15479870
申请日:2017-04-05
IPC分类号: A61M16/10 , A61K33/00 , A61K9/00 , A61M16/06 , A61M16/12 , B01D53/34 , C01B21/24 , A61M15/00 , B01D53/00
摘要: A reaction and distribution system may include a distributor securable near or in a path correspond to a breathing passage such as the nostrils or the mouth of a user for delivering nitric oxide therapy thereto. The distributor may contain an internal reactor for creating the nitric oxide from reactants. Alternative embodiments may include an inhaler for delivering nitric oxide into the mouth of a user. The inhaler may contain a reaction chamber monolithic or contiguous with the inhaler for creating the nitric oxide from reactants.
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