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公开(公告)号：US12226610B2
公开(公告)日：2025-02-18
申请号：US18104979
申请日：2023-02-02
Applicant: Pacira Pharmaceuticals, Inc.
Inventor： Roy Winston , Mary DiGiorgi
Abstract: In some embodiments provided herein are methods of administering an adductor canal block in a patient, wherein the methods include: (a) selecting an entry point of an injection needle in a leg of the patient; (b) inserting the injection needle into the leg of the patient at the entry point; (c) identifying a first nerve in the leg of the patient; (d) administering to the first nerve saline and a pharmaceutical composition; (e) identifying a second nerve in the leg of the patient; (f) administering to the second nerve saline and the pharmaceutical composition; wherein the first nerve and second nerve are selected from the group consisting of the nerve to vastus medialis (NVM) and the saphenous nerve, and wherein the first nerve is not the second nerve, and wherein the pharmaceutical composition comprises multivesicular liposomes.
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公开(公告)号：US12226341B2
公开(公告)日：2025-02-18
申请号：US18282124
申请日：2022-03-24
Applicant: OCULAR THERAPEUTIX, INC.
Inventor： Peter Jarrett , Erik Wong , Eric Dickinson
Abstract: A system (100) includes a first assembly (110A) and a second assembly (110B). The first assembly (110A) includes a body (120) forming a first interior volume, a plunger (130) comprising a first distal end disposed within the first interior volume, a wire comprising a first distal end secured to the first distal end of the plunger (130), and a plunger clip (140) configured to interface with the plunger (130) and the body (120) to prevent actuation of the plunger (130). The second assembly (110B) includes a cowl (150) forming a second interior volume, a needle comprising a hub and a shaft, and a cowl cap disposed partially within the hub to secure the implant in the shaft. A first distal end of the shaft is connected to the hub. The hub is disposed within the second interior volume. The shaft is configured to receive an implant.
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公开(公告)号：US12214159B2
公开(公告)日：2025-02-04
申请号：US17446271
申请日：2021-08-27
Applicant: Capillary Biomedical, Inc.
Inventor： Keith A. Oberg , Mark C. Estes , Kenneth C. Hsu , David S. Gillett
Abstract: Embodiments of devices and methods to maintain preservative concentration in a medication delivered using a medical device are provided. A barrier layer can be used to prevent migration of preservatives. A vent can be used to allow release of preservatives prior to delivery to the patient. An absorbent element can be used to maintain preservative concentration at a desired level. A filter can be used to capture particulates from the medication prior to delivery to a patient.
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公开(公告)号：US20250025625A1
公开(公告)日：2025-01-23
申请号：US18748767
申请日：2024-06-20
Applicant: MEDTRONIC MINIMED, INC.
Inventor： David C. Antonio , Alford L. McLevish
Abstract: The present technology includes, for example, an insertion assembly comprising a frame including a tubular sidewall defining an internal cavity and a slot extending longitudinally along a portion of the sidewall. The insertion assembly further comprises a medical device configured to be inserted into the user's skin and a carrier carrying the medical device and at least partially disposed within the internal cavity of the frame. The carrier can be axially movable within the frame from a first, cocked position to a second extended position proximate. The carrier can include a protrusion disposed within the slot of the frame and configured to slide within the slot when the carrier moves axially within the frame. A ratio of a height of the protrusion to a width of the protrusion is greater than 1.
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公开(公告)号：US12194200B2
公开(公告)日：2025-01-14
申请号：US17173289
申请日：2021-02-11
Applicant: Trustees of Tufts College
Inventor： David L. Kaplan , Konstantinos Tsioris , Fiorenzo G. Omenetto , Eleanor M. Pritchard
Abstract: A microneedle or microneedle device includes a microneedle body extending from a base to a penetrating tip formed from a silk fibroin based material, which is easy to fabricate and highly biocompatible. The microneedle device can include one or more microneedles mounted to a substrate. The silk fibroin can include active agents to be transported into or across biological barriers such as skin, tissue and cell membranes. The silk fibroin microneedles can be fully or partially biodegradable and/or bioerodible. The silk fibroin is highly stable, affords room temperature storage and is implantable. The silk fibroin structure can be modulated to control the rate of active agent delivery.
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Patent Agency Ranking
公开(公告)号：US20250009962A1
公开(公告)日：2025-01-09
申请号：US18888987
申请日：2024-09-18
Applicant: Medtronic MiniMed, Inc.
Inventor： An Thien Pham , Matthew William Yavorsky , Amith Wijesuriya , Yevgeniy Levin
Abstract: A flexible tubing for a cannula has a hollow tubing body having a length dimension from a first end to a second end, and an outer diameter of no more than 0.9 mm. The tubing body has a section of enhanced flexibility of a greater flexibility than one or more other sections of the tubing body. The section of enhanced flexibility is spaced from the first end of the tubing body by a distance D, where D is within a range of 3.0 mm to 5.0 mm for a flexible tubing having a length of about 9.0 mm, and where D is within a range of 1.0 mm to 2.9 mm for a flexible tubing having a length of about 6.0 mm.
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公开(公告)号：US20250001073A1
公开(公告)日：2025-01-02
申请号：US18697785
申请日：2022-10-26
Applicant: Eli Lilly and Company
Inventor： Mary Teresa CARTER
IPC: A61M5/158
Abstract: Inserter devices provide manual insertion of an insertion needle and cannula and subsequent automatic retraction of the insertion needle. The inserter devices include insertion guards that inhibit insertion of the insertion needle and cannula unless a compressive force applied to the device exceeds a threshold. As the user applies more compressive force, the device remains unactuated until the threshold-force is exceeded, whereupon the movement is sudden and rapid. As a result, it feels to the user that the insertion is being driven by an automatic insertion mechanism.
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公开(公告)号：US12178969B2
公开(公告)日：2024-12-31
申请号：US17185453
申请日：2021-02-25
Applicant: Hospital for Special Surgery
Inventor： Stavros Memtsoudis
Abstract: A multi-catheter infusion system and method for the localized delivery of medications while minimally affecting patient mobility for an extended period of time. The multi-catheter infusion system includes a cannula and a plurality of catheters. The cannula includes a first end for connecting to a drug delivery system and a second end for connecting to the plurality of catheters. The plurality of catheters are in fluid communication with the cannula for delivering a drug to a target area of a patient. Each catheter includes a multi-orifice distal end.
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公开(公告)号：US12171982B2
公开(公告)日：2024-12-24
申请号：US18134148
申请日：2023-04-13
Applicant: Becton, Dickinson and Company
Inventor： Ralph Sonderegger
Abstract: A needle stick prevention device (10, 110) includes a needle shield (20, 120) for selectively covering a distal end of a needle (41, 141). A needle hub (40, 140) is movably received within the needle shield (20, 120). The needle hub (40, 140) includes a proximal end (42, 142), a distal end (46, 146), a needle (41, 141) fixedly connected to the distal end of the needle hub (40, 140), and a plurality of ribs (54) or a cylinder (150) disposed between the proximal and distal ends. An actuation button movably received in a transverse opening of the needle shield (20, 120) to engage the needle shield (20, 120), the needle hub (40, 140) and a medical device. A spring (58, 158) is disposed between the needle hub (40, 140) and actuation member to automatically retract the needle (41, 141) into the needle shield (20, 120).
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公开(公告)号：US12161532B2
公开(公告)日：2024-12-10
申请号：US16950470
申请日：2020-11-17
Applicant: University of Kansas
Inventor： Stephen Cilfford Waller , Dhaval Bhavsar
IPC: A61F13/02 , A61F13/00 , A61F13/0246 , A61F15/00 , A61M5/14 , A61M5/158 , A61M25/02 , A61M39/02 , A61M39/24
Abstract: A barrier system is provided for use in reducing infections associated with post-operative surgical incision and/or a percutaneous medical device, such as a catheter, that is disposed within the surgical incision. Such a barrier system may include: a barrier device having a skin-contacting surface and a catheter-receiving surface; and an adhesive composition configured for adhering to skin, the barrier device, and/or the catheter so as to form a barrier at or adjacent to an incision in the skin where the catheter is percutaneously inserted through the skin. A tensioning anchor and associated system of two or more tensioning anchors is provided for post-operative wound closure. A method for applying and removing the barrier device and tensioning anchors is also provided.
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