知搜-全球专利检索

  1. 登录
  2. 注册

搜索结果

257 条记录 (耗时 0.023 秒)

    Acellular soft tissue-derived matrices and methods for preparing same
    3.
    发明授权
    Acellular soft tissue-derived matrices and methods for preparing same 有权

    公开(公告)号：US10912864B2

    公开(公告)日：2021-02-09

    申请号：US16428505

    申请日：2019-05-31

    申请人： Musculoskeletal Transplant Foundation

    发明人： Benjamin Schilling ,  Andrew Madans ,  Abigail Phipps ,  Thomas Tylutki ,  Todd Nilsen ,  Yen-Chen Huang ,  Evangelia Chnari

    IPC分类号： A61L27/40 ,  A61L27/38

    摘要： Compositions including a first soft tissue-derived matrix and a second soft tissue-derived matrix are provided, as well as methods of making such compositions. In some embodiments, the composition comprises delipidated, decellularized adipose tissue-derived matrix and delipidated, decellularized fascial tissue-derived matrix, which may be combined in various proportions. Such adipose-fascia matrix compositions provide improved volume retention when implanted into a patient. The composition may further include exogenous cells or other substances, and/or a carrier. The composition is suitable for use inplastic surgery procedures, including reconstructive or cosmetic surgery procedures, as well as procedures for wound treatment and tissue regeneration. The methods for making the compositions may involve separation of first and second soft tissues from one another, followed by performing one or more treatments on the separated soft tissues, then combining the treated soft tissues and, optionally, performing one or more additional treatments on the combined soft tissues.

    REINFORCED TISSUE GRAFT
    5.
    发明申请
    REINFORCED TISSUE GRAFT 审中-公开

    公开(公告)号：US20200316256A1

    公开(公告)日：2020-10-08

    申请号：US16903920

    申请日：2020-06-17

    申请人： THE CLEVELAND CLINIC FOUNDATION

    发明人： Kathleen Derwin ,  Amit Aurora ,  Joseph P. Iannotti ,  Jesse A. McCarron

    IPC分类号： A61L27/36 ,  A61F2/08 ,  A61L27/40 ,  A61L27/54

    摘要： One aspect of the present disclosure can include a biocompatible tissue graft. The graft can include an extracellular matrix (ECM) patch or strip and at least one fiber stitched into the ECM patch or strip in a peripheral reinforcement pattern. The at least one fiber can have opposing terminal ends. The at least one fiber can mitigate tearing and/or improve fixation retention of the ECM patch or strip. The at least one fiber can comprise a plurality of interconnected stitches. The opposing terminal ends of the at least one fiber can be stitched together to form a continuous stitching construction.

    System for manufacturing fiber scaffolds for use in tracheal prostheses
    8.
    发明授权
    System for manufacturing fiber scaffolds for use in tracheal prostheses 有权

    公开(公告)号：US10562225B2

    公开(公告)日：2020-02-18

    申请号：US14570853

    申请日：2014-12-15

    申请人： NANOFIBER SOLUTIONS, INC.

    发明人： Jed K. Johnson

    IPC分类号： B29C67/00 ,  A61F2/20 ,  B29C64/00 ,  A61L27/36 ,  A61L27/38 ,  A61L27/40 ,  A61F2/04 ,  B29K67/00 ,  B29K75/00 ,  B29K311/00

    摘要： A system for manufacturing a synthetic organ suitable for transplantation into a biological organism is provided. This synthetic organ includes a three-dimensional polymer scaffold, wherein the shape and dimensions of the polymer scaffold are based on a native organ, wherein the polymer scaffold further includes at least one layer of polymer fibers that have been deposited by electrospinning, and wherein the orientation of the fibers in the scaffold relative to one another is generally parallel, random, or both; and wherein the polymer scaffold has been preseeded with at least one type of biological cell prior to implantation into a biological organism, and wherein the at least one type of biological cell is operative to facilitate integration of the polymer scaffold into the organism so that the polymer scaffold may function in a manner significantly similar to or the same as the native organ.

    Absorbable iron-based alloy medical instrument implant and manufacturing method
    9.
    发明授权
    Absorbable iron-based alloy medical instrument implant and manufacturing method 有权

    公开(公告)号：US10543296B2

    公开(公告)日：2020-01-28

    申请号：US15767610

    申请日：2016-06-07

    申请人： Lifetech Scientific (Shenzhen) Co., Ltd.

    发明人： Haiping Qi ,  Ziqiang Liu ,  Li Qin ,  Deyuan Zhang ,  Wenjiao Lin

    IPC分类号： A61L27/04 ,  A61L27/54 ,  A61L27/58 ,  A61L27/18 ,  A61L27/40 ,  A61L31/12

    摘要： Absorbable iron-based alloy implanted medical device and manufacturing method thereof. The iron-based alloy implanted medical device comprises an iron-based alloy substrate (11), a degradable polymer layer (13) disposed on a surface of the iron-based alloy substrate (11), and a tannic acid chemical conversion film (12) disposed on a surface of the iron-based alloy substrate (11). After the medical device is implanted into a body, the tannic acid chemical conversion film (12) is configured to protect the iron-based alloy substrate (11) coated thereby from being in contact with a body fluid, thereby ensuring that the device meets a clinical mechanical property requirement in the early stage of implantation. Furthermore, the iron-based alloy implanted medical device has a decreased size, and produces a decreased amount of a corrosive product after being implanted, facilitating faster absorption or elimination of the corrosive product.