METHOD FOR PRODUCING CYCLIC DIKETONE COMPOUND

    公开(公告)号:US20170362153A1

    公开(公告)日:2017-12-21

    申请号:US15533251

    申请日:2015-12-22

    Abstract: Provided is a method for producing a compound represented by general formula (I) by oxidative cleavage of a compound of formula (II), which is a bicyclic tetrasubstituted olefin compound, using hydrogen peroxide. The method for producing a compound represented by general formula (I) includes a step of subjecting a compound represented by general formula (II) to oxidative cleavage using hydrogen peroxide in the presence of an acid catalyst or in the presence of a tungstic acid compound to obtain the compound represented by general formula (I): [In the formulae, formula -A1- (where the front bond denotes a bond that bonds with a carbon atom C1 while the back bond denotes a bond that bonds with a carbon atom C2) is an alkylene group having 2 to 6 carbon atoms that may have been substituted and that may further include an ether bond, an ester bond, a secondary amino group, a thioether group, or these, and formula -A2- (where the front bond denotes a bond that bonds with a carbon atom C1 while the back bond denotes a bond that bonds with a carbon atom C2) is an alkylene group having 4 to 10 carbon atoms that may have been substituted and that may further include an ether bond, an ester bond, a secondary amino group, a thioether group, or these.]

    Cycloalkane Oxidation Catalysts and Method to Produce Alcohols and Ketones
    3.
    发明申请
    Cycloalkane Oxidation Catalysts and Method to Produce Alcohols and Ketones 有权
    环烷氧化催化剂和生产醇和酮的方法

    公开(公告)号:US20150175514A1

    公开(公告)日:2015-06-25

    申请号:US14416977

    申请日:2012-07-26

    Abstract: Disclosed is a method of oxidizing a cycloalkane to form a product mixture containing a corresponding alcohol and ketone, said method comprising contacting a cycloalkane with a hydroperoxide in the presence of a catalytic effective amount of a crystalline MWW-type titanosilicate catalyst. Hydroperoxides may notably be tert-butyl hydroperoxide, tert-amyl hydroperoxide, cumene hydroperoxide, ethylbenzene hydroperoxide, cyclohexyl hydroperoxide, methylcyclohexyl hydroperoxide, tetralin hydroperoxide, isobutylbenzene hydroperoxide, and ethylnaphthalene hydroperoxide.

    Abstract translation: 公开了一种氧化环烷烃以形成含有相应的醇和酮的产物混合物的方法,所述方法包括在催化有效量的结晶MWW型钛硅酸盐催化剂的存在下使环烷烃与氢过氧化物接触。 氢过氧化物可以特别是叔丁基过氧化氢,叔戊基过氧化氢,氢过氧化枯烯,氢过氧化乙苯,环己基氢过氧化物,甲基环己基氢过氧化物,四氢化萘氢过氧化物,异丁基苯氢过氧化物和乙基萘氢过氧化物。

    Process for the production of a cycloalkanone and/or a cycloalkanol
    5.
    发明授权
    Process for the production of a cycloalkanone and/or a cycloalkanol 失效
    制备环烷酮和/或环烷醇的方法

    公开(公告)号:US5334768A

    公开(公告)日:1994-08-02

    申请号:US12859

    申请日:1993-02-03

    CPC classification number: C07C45/58 C07C29/132 C07C45/53 C07C2101/14

    Abstract: The invention relates to a process for the preparation of cycloalkanone and optionally cycloalkanol by causing a mixture containing cycloalkylhydroperoxide to react with cycloalkene under the influence of a catalyst, characterised in that the reaction is carried out with a short measure of cycloalkene relative to the cycloalkylhydroperoxide, under such conditions that virtually all of the cycloalkene reacts to cycloalkene oxide and optionally cycloalkanol and/or cycloalkanone, after which the mixture, optionally after decomposition of cycloalkylhydroperoxide and distillation of cycloalkane, is subjected to a first separation, in which cycloalkene oxide--and optionally other components--is separated, after which the cycloalkene oxide in the separated mixture is isomerised to substantially cycloalkanone, after which the cycloalkanone obtained--and optionally cycloalkanol--is recovered.

    Abstract translation: 本发明涉及一种制备环烷酮和任选的环烷醇的方法,其中使含有环烷基氢过氧化物的混合物在催化剂的作用下与环烯烃反应,其特征在于该反应用相对于环烷基氢过氧化物的较短量程的环烯烃进行, 在这样的条件下,几乎所有的环烯烃都与环烯烃氧化物和任选的环烷醇和/或环烷酮反应,之后任选地在环烷基氢过氧化物的分解和环烷烃的蒸馏之后混合物经受第一次分离,其中环氧烷 - 和任选地 分离其中的组分,然后将分离的混合物中的环氧烷氧化物异构化为基本上环烷酮,之后回收获得的环烷酮和任选的环烷醇。

    Dispirotetradecanes
    7.
    发明授权

    公开(公告)号:US4853151A

    公开(公告)日:1989-08-01

    申请号:US112356

    申请日:1987-08-11

    Abstract: Dispirotetradecanes of the formula I ##STR1## wherein R.sup.1 and R.sup.2 are each independently of each other alkyl containing 1 to 12 carbon atoms wherein one or more non-adjacent CH.sub.2 groups may also be replaced by --O--, --CO--, --CO--O--, --O--CO--, --O--COO-- and/or --CH.dbd.CH-- (trans), one of the radicals R.sup.1 and R.sup.2 also being H, F, Cl, Br, I, CN, NO.sub.2, NCS,A.sup.1 and A.sup.2 are each independently of each other trans-1,4-cyclohexylene wherein one or two non-adjacent CH.sub.2 groups may be replaced by --O-- and/or --S--, or 1,4-phenylene wherein one or more CH groups may also be replaced by N, with it also being possible optionally for A.sup.1 and A.sup.2 to be substituted laterally or axially by F, Cl, CN, CH.sub.3,Z.sup.1 and Z.sup.2 are each independently of each other --C--O--, --O--CO--, --CH.sub.2 CH.sub.2 --, --CH.sub.2 O--, --OCH.sub.2 -- or a single bond,m and n are each 0, 1 or 2,(m+n) 0, 1 or 2,X.sup.1, X.sup.2, X.sup.3 and X.sup.4 are each independently of each other H, F, Cl or CN, and one or both of the groups CX.sup.1 X.sup.2 and CX.sup.3 X.sup.4 may also be C.dbd.O, may be used as components of liquid-crystalline phases.

    Abstract translation: PCT No.PCT / EP86 / 00722 Sec。 371日期1987年8月11日 102(e)日期1987年8月11日PCT提交1986年12月8日PCT公布。 公开号WO87 / 03581 日期:1987年6月18日。式I的对映异十四烷酮其中R 1和R 2各自独立地为彼此具有1至12个碳原子的烷基,其中一个或多个不相邻的CH 2基团也可被-O- ,-CO-,-CO-O-,-O-CO-,-O-COO-和/或-CH = CH-(反式),基团R1和R2之一也是H,F,Cl,Br ,I,CN,NO 2,NCS,A 1和A 2各自独立地为彼此反式-1,4-亚环己基,其中一个或两个不相邻的CH 2基可以被-O-和/或-S-或1 其中一个或多个CH基团也可以被N代替的4-亚苯基,也可以任选地使A1和A2被F,B,CN,CH 3,Z 1和Z 2各自独立地取代为横向或轴向被F,Cl,CN, 其它-CO-,-O-CO-,-CH2CH2-,-CH2O-,-OCH2-或单键,m和n分别为0,1或2,(m + n)0,1或2,X1 ,X2,X3和X4各自独立地为H,F,Cl或CN,并且基团CX1X2和CX3X4中的一个或两个也可以是C = O,可以用作组分 的液晶相。

    4,5-Secoandrostanes
    10.
    发明授权
    4,5-Secoandrostanes 失效
    4,5-二十二烷

    公开(公告)号:US3984474A

    公开(公告)日:1976-10-05

    申请号:US582014

    申请日:1975-05-30

    CPC classification number: C07D309/12 C07J71/001 C07C2103/16

    Abstract: 4,5-Secoandrostanes having the formula ##SPC1##Have useful anti-inflammatory activity wherein R.sub.1 is hydrogen and R.sub.2 is hydroxyl, R.sub.1 is hydroxyl and R.sub.2 is hydrogen, R.sub.1 and R.sub.2 are each hydrogen, or together R.sub.1 and R.sub.2 are =0; R.sub.3 is hydrogen and R.sub.4 is hydroxyl, R.sub.3 is hydroxyl and R.sub.4 is hydrogen, R.sub.3 and R.sub.4 are each hydrogen, or together R.sub.3 and R.sub.4 are =0; R.sub.5 is hydrogen or hydroxyl; and R.sub.6 is hydrogen or halogen.

    Abstract translation: 具有下式的4,5-山and雄甾醇具有有效的抗炎活性,其中R 1是氢,R 2是羟基,R 1是羟基,R 2是氢,R 1和R 2各自是氢,或者R 1和R 2一起= 0; R3是氢,R4是羟基,R3是羟基,R4是氢,R3和R4各自是氢,或者R3和R4一起= 0; R5是氢或羟基; R6是氢或卤素。

Patent Agency Ranking