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    Systems and methods for generating nitric oxide
    4.
    发明授权
    Systems and methods for generating nitric oxide 有权

    公开(公告)号：US11479464B2

    公开(公告)日：2022-10-25

    申请号：US16875971

    申请日：2020-05-15

    申请人： Third Pole, Inc.

    发明人： Gregory W. Hall ,  Benjamin J. Apollonio ,  Ian J. Gillerman

    IPC分类号： C01B21/20 ,  A61M16/06 ,  A61M16/10 ,  H01J37/32 ,  H01J37/04 ,  A61M16/12 ,  A61M16/00

    摘要： Systems and methods for generating nitric oxide are disclosed. A nitric oxide (NO) generation system includes at least one pair of electrodes configured to generate a product gas containing NO from a flow of a reactant gas; and a controller configured to regulate the amount of nitric oxide in the product gas produced by the at least one pair of electrodes by utilizing duty cycle values of plasma pulses selected from a plurality of discrete duty cycles to produce a target rate of NO production based on an average of discrete production rates associated with each of the plurality of discrete duty cycles.

    Inspiratory synthesis of nitric oxide
    6.
    发明授权
    Inspiratory synthesis of nitric oxide 有权

    公开(公告)号：US10434276B2

    公开(公告)日：2019-10-08

    申请号：US16058797

    申请日：2018-08-08

    申请人： THE GENERAL HOSPITAL CORPORATION

    发明人： Warren M. Zapol ,  Binglan Yu ,  Paul Hardin ,  Matthew Hickcox

    IPC分类号： A61M16/12 ,  A61M16/10 ,  B01D53/56 ,  A61M16/00 ,  C01B21/20 ,  A61M16/04 ,  A61M16/06 ,  A61M16/20 ,  A61M15/02

    摘要： A system for generating nitric oxide can include an apparatus positioned in a trachea of a mammal, the apparatus in eluding a respiration sensor for collecting information related to one or more triggering events associated with the trachea, an oxygen sensor for collecting information related to a concentration of oxygen in a gas, and one or more pairs of electrodes for initiating a series of electric arcs to generate nitric oxide, and the system for generating nitric oxide can also include a controller for determining one or more control parameters based on the information collected by the respiration sensor and the oxygen sensor, wherein the series of electric arcs is initiated based on the control parameters determined by the controller.

    Inspiratory synthesis of nitric oxide
    7.
    发明授权
    Inspiratory synthesis of nitric oxide 有权

    公开(公告)号：US10293133B2

    公开(公告)日：2019-05-21

    申请号：US14777072

    申请日：2014-03-14

    申请人： THE GENERAL HOSPITAL CORPORATION

    发明人： Warren M. Zapol ,  Binglan Yu ,  Paul Hardin ,  Matthew Hickcox

    IPC分类号： A61M16/12 ,  A61M16/10 ,  B01D53/56 ,  A61M16/00 ,  C01B21/20 ,  A61M16/04 ,  A61M16/06 ,  A61M16/20 ,  A61M15/02

    摘要： A system for generating nitric oxide can include an apparatus positioned in a trachea of a mammal, the apparatus including a respiration sensor for collecting information related to one or more triggering events associated with the trachea, an oxygen sensor for collecting information related to a concentration of oxygen in a gas, and one or more pairs of electrodes for initiating a series of electric arcs to generate nitric oxide, and the system for generating nitric oxide can also include a controller for determining one or more control parameters based on the information collected by the respiration sensor and the oxygen sensor, wherein the series of electric arcs is initiated based on the control parameters determined by the controller.