公开(公告)号：US20230404078A1

公开(公告)日：2023-12-21

申请号：US18250269

申请日：2021-10-26

Applicant: Adama Agan Ltd.

Inventor： Hadas MIRYAMCHIK ,  Ehud YOGEV ,  Grant CURTIS ,  Martin HUTTENLOCHER

IPC: A01N43/40 ,  A01N33/24 ,  A01N43/60 ,  A01P13/00

CPC classification number: A01N43/40 ,  A01N33/24 ,  A01N43/60 ,  A01P13/00

Abstract: The present invention relates to Halauxifen based multi component, and particularly two-component herbicides, comprising, combinations, that comprise, as component (a) Halauxifen, and agriculturally acceptable derivatives including salts and esters thereof, and most particularly, Halauxifen-methyl, applied with component (b) co-herbicides which are each chosen to be tailored to be particularly useful in combination with a) for weed control options in specific crops, weeds and application modalities, be they cereals, oilseed rape, sunflower and soy crops. The b) co-herbicides are each chosen from, Propaquizafop; Clethodim; and any and all combinations thereof, for tailored and or selective control of unwanted vegetation. Besides other advantages, the invention has particular utility in inter alia, reducing each herbicidally active ingredient in the multi component, and particularly two-component herbicide to below the herbicidally effective amount applied while providing selective control of undesired vegetation or weeds, particularly Broadleaf weeds.

公开(公告)号：US20230127143A1

公开(公告)日：2023-04-27

申请号：US17759640

申请日：2021-01-29

Applicant: SUMITOMO CHEMICAL COMPANY, LIMITED

Inventor： Yuichi MATSUZAKI ,  Takaaki NAKANO ,  Hidekatsu TOBITA ,  Hiroto TAMASHIMA ,  Keisuke ARAI

IPC: A01N43/32 ,  A01N33/24 ,  A01N37/06 ,  A01N37/34 ,  A01N37/44 ,  A01N37/52 ,  A01N41/10 ,  A01N43/40 ,  A01N43/56 ,  A01N43/88 ,  A01P3/00 ,  C07C251/60 ,  C07C69/54

Abstract: The present invention provides a method for controlling a soybean rust fungus having an amino acid substitution of F129L on mitochondrial cytochrome b protein. According to the present invention, a compound represented by formula (I) [wherein R1 represents a C1-C3 chain hydrocarbon group and so on, n is 0, 1, 2 or 3, and when is 2 or 3, a plural of R2 may be identical to or different from each other, and R2 represents a C1-C3 chain hydrocarbon group and so on, Q represents a group represented by Q1 (where • represents a binding site to a benzene ring) and so on, L1 represents CH2 or an oxygen atom, and E represents a C1-C6 alkyl group and so on.] can use to control a soybean rust fungus having an amino acid substitution of F129L on mitochondrial cytochrome b protein.

公开(公告)号：US09452119B2

公开(公告)日：2016-09-27

申请号：US14819859

申请日：2015-08-06

Applicant: Dow Global Technologies LLC

Inventor： Mrunalini S. Dhamdhere ,  George D. Green ,  Shao-Ching Hung ,  Raymond J. Swedo

IPC: A01N33/24 ,  A61K31/15 ,  A61K8/40 ,  A61Q19/08 ,  C07C291/02

CPC classification number: A61K8/40 ,  A61K2800/522 ,  A61Q19/08 ,  C07C291/02

Abstract: Provided are compounds and compositions thereof that are useful as antioxidants in personal care formulations. The compounds are of the formula I: wherein R, R1, R2, R3, R4, R5 and R6 are as defined herein.

公开(公告)号：US20160198705A1

公开(公告)日：2016-07-14

申请号：US14914923

申请日：2014-05-22

Applicant: NINGBO YUCHEN ENVIROCLEAN TECH CO., LTD.

Inventor： ZUOLIN ZHU ,  MENG SUN ,  ZHENJI ZHU ,  KANGFU GU ,  SHANQING SUN ,  TONGXING XIE ,  JIABAO ZHAO ,  WENHAI WANG

IPC: A01N31/08 ,  A61L9/14 ,  A01N33/24 ,  A01N37/40 ,  A01N41/04

CPC classification number: A01N31/08 ,  A01N31/16 ,  A01N33/24 ,  A01N37/40 ,  A01N41/04 ,  A61L9/145 ,  B01D53/72 ,  B01D53/8687 ,  B01D2255/70 ,  B01D2257/708 ,  B01D2257/91 ,  B01D2258/06

Abstract: The present invention relates to an application of bisphenol salts in preparing a disinfectant used for sterilization or formaldehyde removal. The present invention provides a sterilization and disinfection system that uses oxygen in the air as oxidizer, kills microorganisms via catalyzed oxidation, and is particularly suitable in an air purification system. The disinfectant of the present invention can be used for an extended period of time insofar that air is continuously introduced, obviates the need for an anti-viral agent, also obviates the need for a peroxide that is potentially hazardous to safety, uses no halogen-containing irritating substance, and use no alcohol having risk of explosion. This disinfectant system that uses no precious metal is easy to prepare, low in use cost, and free of secondary pollution, and provides a good application prospect.

Abstract translation: 本发明涉及双酚盐在制备用于灭菌或甲醛去除的消毒剂中的应用。 本发明提供一种使用空气中的氧气作为氧化剂的灭菌消毒系统，通过催化氧化杀死微生物，特别适用于空气净化系统。 本发明的消毒剂可以在连续引入空气的情况下长时间使用，消除了对抗病毒剂的需要，也避免了对潜在地危害安全的过氧化物的需要，不使用卤素 - 含有刺激性物质，不使用有爆炸危险的酒精。 不含贵金属的消毒系统易于准备，使用成本低，无二次污染，具有良好的应用前景。

公开(公告)号：US20160106100A1

公开(公告)日：2016-04-21

申请号：US14894416

申请日：2014-05-23

Applicant: Scott BETTS ,  Graham LAWSON ,  Marta URIZAL COMAS ,  Roman GRABBE ,  Rüdiger BAUM

Inventor： Scott BETTS ,  Graham Lawson ,  Marta URIZAL COMAS ,  Roman GRABBE ,  Rüdiger BAUM

IPC: A01N43/80 ,  A61K8/41 ,  A61K8/49 ,  A61Q19/00 ,  A01N33/24 ,  A01N33/12

CPC classification number: A01N43/80 ,  A01N33/12 ,  A01N33/16 ,  A01N33/24 ,  A61K8/40 ,  A61K8/416 ,  A61K8/49 ,  A61K2800/10 ,  A61K2800/524 ,  A61K2800/596 ,  A61K2800/74 ,  A61Q17/005 ,  A61Q19/00 ,  C11D3/28 ,  C11D3/48 ,  A01N37/34 ,  A01N59/00

Abstract: The present invention relates to a microbicidal composition in the form of a concentrate and to the use of the composition for the preservation of technical and domestic products, preferred for the preservation of wet wipes.

Abstract translation: 本发明涉及浓缩物形式的杀微生物组合物以及用于保存技术和家用产品的组合物的用途，优选用于湿巾的保存。

公开(公告)号：US09084754B2

公开(公告)日：2015-07-21

申请号：US13525108

申请日：2012-06-15

Applicant: Servet Buyuktimkin ,  Nadir Buyuktimkin ,  Jagat Singh ,  John M. Newsam ,  Dominic King-Smith ,  Edward Kisak

Inventor： Servet Buyuktimkin ,  Nadir Buyuktimkin ,  Jagat Singh ,  John M. Newsam ,  Dominic King-Smith ,  Edward Kisak

IPC: A01N33/02 ,  A01N33/24 ,  A61K31/13 ,  A61K31/135 ,  A61K31/137 ,  A61K9/00 ,  A61K47/10 ,  A61K47/12 ,  A61K47/18 ,  A61K47/20 ,  A61K47/34 ,  A61K47/38

CPC classification number: A61K31/137 ,  A61K9/0017 ,  A61K47/10 ,  A61K47/12 ,  A61K47/18 ,  A61K47/186 ,  A61K47/20 ,  A61K47/34 ,  A61K47/38

Abstract: The present invention provides topical compositions, methods of preparation, and methods of treatment for onychomychosis. In certain specific embodiments, the invention provides an anti-fungal pharmaceutical composition for topical application comprising an anti-fungal agent, a zwitterionic surfactant or charged derivative thereof; a carboxylic acid, a lower alcohol, and water. The acid is selected from a short-chain hydroxy acid, a short-chain fatty acid, and a mixture thereof. In certain other specific embodiments, the invention provides an anti-fungal pharmaceutical composition for topical application comprising an anti-fungal agent, a quarternary amino acid, a keratolytic agent; a lower alcohol; and water. In certain embodiments, the keratolytic agent is urea, ammonium thioglycolate, or a mixture thereof.

Abstract translation: 本发明提供局部用组合物，制备方法和治疗甲真菌病的方法。 在某些具体实施方案中，本发明提供用于局部施用的抗真菌药物组合物，其包含抗真菌剂，两性离子表面活性剂或其带电衍生物; 羧酸，低级醇和水。 酸选自短链羟基酸，短链脂肪酸及其混合物。 在某些其他具体实施方案中，本发明提供了用于局部应用的抗真菌药物组合物，其包含抗真菌剂，季铵氨基酸，角质分解剂; 低级酒精; 和水。 在某些实施方案中，角质分解剂是尿素，巯基乙酸铵或其混合物。

公开(公告)号：US08877806B2

公开(公告)日：2014-11-04

申请号：US13747508

申请日：2013-01-23

Applicant: SK Biopharmaceuticals Co., Ltd.

Inventor： Abdallah Ahnaou ,  Wilhelmus H. I. M. Drinkenburg ,  Joseph Palumbo ,  Jonathan Sporn

IPC: A01N47/10 ,  A61K31/27 ,  A01N33/02 ,  A61K31/135 ,  A01N33/18 ,  A01N33/24 ,  A61K31/04 ,  A61K31/165

CPC classification number: C07C271/12 ,  A61K9/0053 ,  A61K31/165 ,  A61K31/27

Abstract: This invention is directed to a method of treating Excessive daytime Sleepiness (EDS) in a subject, comprising the step of administering a therapeutically effective amount of a compound of Formula (I): Formula (I) or a pharmaceutically acceptable salt or ester thereof wherein Rx is a member selected from the group consisting of hydrogen, lower alkyl of 1 to 8 carbon atoms, halogen selected from F, Cl, Br and I, alkoxy containing 1 to 3 carbon atoms, nitro, hydroxy, trifluoromethyl, and thioalkoxy containing 1 to 3 carbon atoms; x is an integer of 1 to 3, with the proviso that R may be the same or different when x is 2 or 3; R1 and R2 can be the same or different from each other and are independently selected from the group consisting of hydrogen, lower alkyl of 1 to 8 carbon atoms, aryl, arylalkyl, cycloalkyl of 3 to 7 carbon atoms; R1 and R2 can be joined to form a 5 to 7-membered heterocycle substituted with a member selected from the group consisting of hydrogen, alkyl, and aryl groups, wherein the cyclic compound can comprise 1 to 2 nitrogen atoms and 0 to 1 oxygen atom, wherein the nitrogen atoms are not directly connected with each other or with the oxygen atom.

Abstract translation: 本发明涉及一种治疗受试者过度白昼睡眠（EDS）的方法，包括施用治疗有效量的式（I）化合物：式（I）或其药学上可接受的盐或酯的步骤，其中 Rx是选自氢，1至8个碳原子的低级烷基，选自F，Cl，Br和I的卤素，含有1至3个碳原子的烷氧基，硝基，羟基，三氟甲基和含有1个 至3个碳原子; x为1〜3的整数，条件是当x为2或3时R可以相同或不同; R 1和R 2可以相同或不同，并且独立地选自氢，1至8个碳原子的低级烷基，芳基，芳基烷基，3至7个碳原子的环烷基; R1和R2可以连接形成被选自氢，烷基和芳基的成员取代的5至7元杂环，其中环状化合物可包含1至2个氮原子和0至1个氧原子 其中氮原子彼此不直接连接或与氧原子直接连接。

公开(公告)号：US08748468B2

公开(公告)日：2014-06-10

申请号：US13668167

申请日：2012-11-02

Applicant: Pharmacyclics, Inc.

Inventor： David Loury ,  Tarak Mody

IPC: A01N43/52 ,  A61K31/415 ,  A01N37/52 ,  A61K31/155 ,  A01N33/18 ,  A01N33/24 ,  A61K31/045 ,  A61K31/04

CPC classification number: A61K31/4184 ,  A61K31/4164 ,  A61K41/00 ,  A61K45/06 ,  C07D209/00 ,  C07D235/12 ,  C07D235/18 ,  A61K2300/00

Abstract: Treatment of cancer and thromboembolic disorders using inhibitors of Factor VIIa are disclosed herein using a compound of Formula I:

Abstract translation: 本文公开了使用式I化合物治疗因子VIIa抑制剂的癌症和血栓栓塞障碍：

公开(公告)号：US08697753B1

公开(公告)日：2014-04-15

申请号：US13888757

申请日：2013-05-07

Applicant: Polichem SA

Inventor： Federico Mailland ,  Michela Legora ,  Daniela Ceriani ,  Giuliana Iob

IPC: A01N33/02 ,  A01N33/24 ,  A61K31/13 ,  A61K31/135 ,  A01N25/00

CPC classification number: A61K31/137 ,  A61K9/0014 ,  A61K47/10 ,  A61K47/36

Abstract: The present invention is directed to a nail lacquer consisting essentially of terbinafine as an antimycotic agent, hydroxypropyl chitosan as film forming agent, water and a lower alkanol as solvents. The invention is also directed to a method for treating onychomycosis by topically administering such a nail lacquer to a patient in need of such a treatment.

Abstract translation: 本发明涉及一种主要由作为抗真菌剂的特比萘芬，作为成膜剂的羟丙基壳聚糖，水和作为溶剂的低级链烷醇组成的指甲漆。 本发明还涉及通过向需要这种治疗的患者局部施用这种指甲油来治疗甲真菌病的方法。

公开(公告)号：US20140087949A1

公开(公告)日：2014-03-27

申请号：US14111741

申请日：2012-03-28

Applicant: Jens Frackenpohl ,  Thomas Müller ,  Ines Heinemann ,  Pascal Von Koskull-Döring ,  Christopher Hugh Rosinger ,  Isolde Häuser-Hahn ,  Martin Jeffrey Hills

Inventor： Jens Frackenpohl ,  Thomas Müller ,  Ines Heinemann ,  Pascal Von Koskull-Döring ,  Christopher Hugh Rosinger ,  Isolde Häuser-Hahn ,  Martin Jeffrey Hills

IPC: A01N55/00 ,  A01N35/06 ,  A01N33/24 ,  A01N43/30

CPC classification number: A01N55/00 ,  A01N33/24 ,  A01N35/06 ,  A01N37/42 ,  A01N43/30 ,  C07C403/20 ,  C07C2601/02 ,  C07C2601/16 ,  C07D317/72 ,  C07F7/1804 ,  C07F7/2208 ,  C07F7/30 ,  C07F17/00

Abstract: The invention relates to substituted 5-(cyclohex-2-en-1-yl)penta-2,4-dienes and 5-(cyclohex-2-en-1-yl)pent-2-en-4-ines of the formula (I) and their salts where the radicals R1, R2, R3, R4, [X—Y] and Q are each as defined in the description, to processes for preparation thereof and to the use thereof for enhancing stress tolerance in plants with respect to abiotic stress, and/or for increasing plant yield.

Abstract translation: 本发明涉及取代的5-（环己-2-烯-1-基）五-2,4-二烯和5-（环己-2-烯-1-基）戊-2-烯-4-烯 式（I）及其盐，其中基团R 1，R 2，R 3，R 4，[X-Y]和Q各自如说明书中所定义，其制备方法及其用于增强植物中的胁迫耐受性的用途， 尊重非生物胁迫，和/或提高植物产量。