公开(公告)号：US20230174951A1

公开(公告)日：2023-06-08

申请号：US17921120

申请日：2021-04-25

申请人： THE STATE OF ISRAEL, MINISTRY OF AGRICULTURE & RURAL DEVELOPMENT, AGRICULTURAL RESEARCH ORGANIZATION ,  B. G. Negev Technologies and Applications Ltd., at Ben-Gurion University

发明人： Avihai PERL ,  Michal OREN-SHAMIR ,  Miriam FRIEDMAN-EINAT ,  Ru WANG ,  Aaron FAIT

IPC分类号： C12N5/14 ,  C12N15/82 ,  A61P37/06 ,  C12N15/52

CPC分类号： C12N5/14 ,  A61P37/06 ,  C12N15/52 ,  C12N15/8243

摘要： The present invention relates to transgenic grape cells, compositions comprising such cells or extracts or fractions thereof, and methods of use thereof for inhibiting or reducing the incidence of cytokine release syndrome or cytokine storm in a subject. Disclosed herein are also methods for preventing, treating, reducing the incidence, suppressing or inhibiting a coronavirus infection or a symptom thereof.

公开(公告)号：US10015942B2

公开(公告)日：2018-07-10

申请号：US14909935

申请日：2013-08-14

申请人： Bejo Zaden B.V.

发明人： Elizabeth Rosalien de Jong ,  Adriana Dorien Haarsma ,  Witte Van Cappellen ,  Cornelis Glas ,  Nicolaas Anthonius Zutt ,  Albertus Johannes Maria Schrijver

IPC分类号： A01H5/12 ,  A01H1/02 ,  C12N5/14 ,  C12Q1/68 ,  A01H5/02 ,  A01H1/00 ,  C12N15/82 ,  C12Q1/6895

CPC分类号： A01H6/14 ,  A01H1/00 ,  A01H1/02 ,  A01H5/02 ,  A01H5/12 ,  C12N5/14 ,  C12N15/8289 ,  C12Q1/6895 ,  C12Q2600/13 ,  C12Q2600/156

摘要： The present invention relates to cytoplasmic male sterile (CMS) Cichorium plants and especially to cytoplasmic male sterile (CMS) green chicory plants; cytoplasmic male sterile (CMS) radicchio rosso plants; cytoplasmic male sterile (CMS) red leaved chicory plants, cytoplasmic male sterile (CMS) Treviso plants, cytoplasmic male sterile (CMS) white chicory plants, cytoplasmic male sterile (CMS) sugar loaf plants, cytoplasmic male sterile (CMS) Belgian endive plants, cytoplasmic male sterile (CMS) witloof plants, cytoplasmic male sterile (CMS) Catalogna plants, cytoplasmic male sterile (CMS) C. intybus var. foliosum plants, cytoplasmic male sterile (CMS) C. endivia plants and cytoplasmic male sterile (CMS) C. intybus L. var. sativum plants. The present invention further relates to methods for identifying cytoplasmic male sterile (CMS) Cichorium plants and mitochondrial nucleic acid sequences providing cytoplasmic male sterility (CMS) in Cichorium plants.

公开(公告)号：US09695436B2

公开(公告)日：2017-07-04

申请号：US14772276

申请日：2014-03-04

申请人： Bayer CropScience LP

发明人： Chandra McAllister ,  Perrin Beatty ,  Jayne D'Entremont ,  Allen Good

IPC分类号： C12N5/14 ,  C12N15/82 ,  C12N9/10

CPC分类号： C12N15/8261 ,  C12N5/14 ,  C12N9/1096 ,  C12Y206/01002 ,  Y02A40/146

摘要： Methods are provided for enhancing yield and nitrogen use efficiency in plants, and to methods of increasing biomass and seed yield in plants grown under nitrogen limiting conditions using variants of enzymes involved in nitrogen assimilation or metabolism from non-plant organisms.

公开(公告)号：US09642329B2

公开(公告)日：2017-05-09

申请号：US15092835

申请日：2016-04-07

申请人： NUSEED AMERICAS INC.

发明人： Scott Arthur Radi ,  Erin Marie Gerdes

IPC分类号： A01H5/10 ,  C12N5/14 ,  C12N15/82 ,  A01H5/02

CPC分类号： A01H5/10 ,  A01H5/02 ,  C12N5/14 ,  C12N15/8241 ,  C12N15/8274 ,  C12N15/8275 ,  C12N15/8277 ,  C12N15/8278 ,  C12N15/8279 ,  C12N15/8281 ,  C12N15/8282 ,  C12N15/8283 ,  C12N15/8286 ,  C12N15/8289

摘要： The present invention relates to an inbred sunflower, designated SA425A. The invention relates to the seeds of inbred sunflower SA425A, to the plants of inbred sunflower SA425A and to methods for producing a sunflower plant by crossing cultivar SA425A with itself or another sunflower. The invention further relates to methods for producing a sunflower plant containing in its genetic material one or more transgenes and to the transgenic sunflower plants and plant parts produced by those methods and to methods for producing other hybrid sunflower derived from inbred sunflower SA425A.

公开(公告)号：US09617556B2

公开(公告)日：2017-04-11

申请号：US14082567

申请日：2013-11-18

申请人： E I DU PONT DE NEMOURS AND COMPANY

发明人： Knut Meyer ,  Kevin L Stecca

IPC分类号： C12N15/82 ,  C12N5/14 ,  C12N9/02

CPC分类号： C12N15/8251 ,  C12N5/14 ,  C12N9/0004 ,  C12N15/8245 ,  C12N15/8247

摘要： This invention is in the field of plant molecular biology. More specifically, this invention pertains to isolated nucleic acid fragments encoding ORM proteins in plants and seeds and the use of such fragments to modulate expression of a gene encoding ORM protein activity in a transformed host cell.

公开(公告)号：US09585353B1

公开(公告)日：2017-03-07

申请号：US15059659

申请日：2016-03-03

申请人： PIONEER HI-BRED INTERNATIONAL, INC.

发明人： Brian Allen Carden ,  Robert John Pearson ,  Jordan Dustin Spear

IPC分类号： A01H5/10 ,  C12N15/82 ,  C12N5/14 ,  A01H1/02

CPC分类号： A01H5/10 ,  A01H1/02 ,  C12N5/14 ,  C12N15/8241 ,  C12N15/8243 ,  C12N15/8245 ,  C12N15/8247 ,  C12N15/8251 ,  C12N15/8271 ,  C12N15/8274 ,  C12N15/8279 ,  C12N15/8286 ,  C12N15/8289

摘要： A novel soybean variety, designated XBP12004R is provided. Also provided are the seeds of soybean variety XBP12004R, cells from soybean variety XBP12004R, plants of soybean XBP12004R, and plant parts of soybean variety XBP12004R. Methods provided include producing a soybean plant by crossing soybean variety XBP12004R with another soybean plant, methods for introgressing a transgenic trait, a mutant trait, and/or a native trait into soybean variety XBP12004R, methods for producing other soybean varieties or plant parts derived from soybean variety XBP12004R, and methods of characterizing soybean variety XBP12004R. Soybean seed, cells, plants, germplasm, breeding lines, varieties, and plant parts produced by these methods and/or derived from soybean variety XBP12004R are further provided.

摘要翻译： 提供了一种名为XBP12004R的新品种。 还提供了大豆品种XBP12004R的种子，大豆品种XBP12004R的细胞，大豆XBP12004R的植物和大豆品种XBP12004R的植物部分。 提供的方法包括通过将大豆品种XBP12004R与另一种大豆植物杂交来生产大豆植物，将转基因性状，突变特征和/或天然性状插入大豆品种XBP12004R中的方法，生产其他大豆品种的方法或衍生自 大豆品种XBP12004R，以及大豆品种XBP12004R的表征方法。 进一步提供通过这些方法生产和/或衍生自大豆品种XBP12004R的大豆种子，细胞，植物，种质，育种系，品种和植物部分。

公开(公告)号：US20150353863A1

公开(公告)日：2015-12-10

申请号：US14834914

申请日：2015-08-25

申请人： James Robertson Petrie ,  Thomas Vanhercke ,  Pushkar Shrestha ,  Qing Liu ,  Surinder Pal Singh

发明人： James Robertson Petrie ,  Thomas Vanhercke ,  Pushkar Shrestha ,  Qing Liu ,  Surinder Pal Singh

IPC分类号： C11B1/10 ,  C12N15/82 ,  A23K1/18 ,  A23D9/00 ,  A23K1/16 ,  C12N9/10 ,  C11B1/06

CPC分类号： C11B1/10 ,  A23D9/00 ,  A23K10/12 ,  A23K20/158 ,  A23K50/80 ,  C10L1/026 ,  C11B1/06 ,  C11C3/003 ,  C12N5/14 ,  C12N9/1025 ,  C12N9/1029 ,  C12N9/1051 ,  C12N15/8218 ,  C12N15/8247 ,  C12Y203/0102 ,  C12Y204/01101 ,  C12Y204/01143 ,  Y02E50/13

摘要： The present invention relates to methods of producing lipids. In particular, the present invention relates to methods of increasing the level of one or more non-polar lipids and/or the total non-polar lipid content in a transgenic organism or part thereof. In one particular embodiment, the present invention relates to the use of an acyltransferase, for example, a monoacylglycerol acyltransferase (MGAT) to increase the level of one or more non-polar lipids and/or the total non-polar lipid content in plants, plant seed and/or leaves, algae and fungi.

摘要翻译： 本发明涉及生产脂质的方法。 特别地，本发明涉及增加转基因生物体或其部分中一种或多种非极性脂质水平和/或总非极性脂质含量的方法。 在一个具体实施方案中，本发明涉及酰基转移酶，例如单酰基甘油酰基转移酶（MGAT）用于增加植物中一种或多种非极性脂质和/或总非极性脂质含量的水平， 植物种子和/或叶，藻类和真菌。

公开(公告)号：US09173359B1

公开(公告)日：2015-11-03

申请号：US13400601

申请日：2012-02-21

申请人： Gustavo Marcelo Garcia

发明人： Gustavo Marcelo Garcia

IPC分类号： A01H5/10 ,  C12N5/14

CPC分类号： A01H5/10 ,  C12N5/14

摘要： A novel maize variety designated PH1DG3 and seed, plants and plant parts thereof. Methods for producing a maize plant that comprise crossing maize variety PH1DG3 with another maize plant. Methods for producing a maize plant containing in its genetic material one or more traits introgressed into PH1DG3 through backcross conversion and/or transformation, and to the maize seed, plant and plant part produced thereby. Hybrid maize seed, plant or plant part produced by crossing the variety PH1DG3 or a locus conversion of PH1DG3 with another maize variety.

摘要翻译： 一种称为PH1DG3的新型玉米品种及其种子，植物和植物部分。 生产玉米植物的方法，包括与另一个玉米植物杂交玉米品种PH1DG3。 用于生产含有其遗传物质的玉米植物的方法通过回交转化和/或转化渗入PH1DG3的一种或多种性状，以及由此生产的玉米种子，植物和植物部分。 通过杂交品种PH1DG3产生的杂种玉米种子，植物或植物部分或与另一种玉米品种的PH1DG3的基因座转化。

公开(公告)号：US20150203858A1

公开(公告)日：2015-07-23

申请号：US14601186

申请日：2015-01-20

申请人： British American Tobacco (Investments) Limited

发明人： Susie DAVENPORT ,  Martin MAUNDERS

IPC分类号： C12N15/82 ,  A01H1/06 ,  C12N9/06

CPC分类号： C12N15/8243 ,  A01H1/04 ,  A01H1/06 ,  C12N5/14 ,  C12N9/0044 ,  C12Y107/02001

摘要： The present invention relates in one aspect to a method for producing a transgenic plant, comprising introducing into an unmodified plant an exogenous gene encoding a nitrite reductase, wherein expression of the nitrite reductase encoded by the exogenous gene reduces nitrite content in the transgenic plant relative to the unmodified plant. Also provided are transgenic plants and plant cells comprising an exogenous gene encoding a nitrite reductase, as well as associated uses, chimaeric genes and plant transformation vectors.

摘要翻译： 本发明在一个方面涉及一种生产转基因植物的方法，包括向未修饰的植物中引入编码亚硝酸还原酶的外源基因，其中由外源基因编码的亚硝酸还原酶的表达降低了转基因植物中的亚硝酸盐含量，相对于 未修改的植物。 还提供了转基因植物和植物细胞，其包含编码亚硝酸还原酶的外源基因，以及相关用途，嵌合基因和植物转化载体。

公开(公告)号：US20150184194A1

公开(公告)日：2015-07-02

申请号：US14129038

申请日：2012-06-19

申请人： Dennis L. Bidney ,  Mark Cigan ,  Carl Falco ,  Huirong Gao ,  Derek Jantz ,  Mike Lassner ,  Keith Lowe ,  Leszek Aleksander Lyznik ,  James Jefferson Smith

发明人： Dennis L. Bidney ,  Mark Cigan ,  Carl Falco ,  Huirong Gao ,  Derek Jantz ,  Mike Lassner ,  Keith Lowe ,  Leszek Aleksander Lyznik ,  James Jefferson Smith

IPC分类号： C12N15/82

CPC分类号： C12N15/8289 ,  C12N5/14 ,  C12N9/22 ,  C12N15/8213 ,  C12Q1/6895 ,  C12Q2600/13 ,  C12Q2600/156 ,  C12Q2600/158 ,  C12Y301/00

摘要： Methods of making a targeted modification in a male fertility gene in the genome of a plant are disclosed. The methods involve contacting a plant cell with an engineered double-strand-break-inducing agent capable of inducing a double-strand break in a target sequence in the male fertility gene and identifying a cell comprising an alteration in the target sequence. Also disclosed are plants, plant cells, plant parts, and seeds comprising a male fertility gene with an alteration in a male fertility gene. Nucleic acid molecules comprising male fertility genes with at least one targeted modification therein, optimized nucleic acid molecules encoding endonucleases that are engineered double-strand-break-inducing agents and expression cassettes, host cells, and plants comprising one or more of the nucleic acid molecules are further disclosed.

摘要翻译： 公开了在植物基因组中对雄性能育基因进行靶向修饰的方法。 所述方法包括使植物细胞与能够在雄性能育基因中的靶序列中诱导双链断裂的工程化双链断裂诱导剂接触，并鉴定包含靶序列改变的细胞。 还公开了包含雄性育性基因改变的雄性育性基因的植物，植物细胞，植物部分和种子。 包含其中具有至少一个靶向修饰的雄性能育基因的核酸分子，编码工程化双链断裂诱导剂和表达盒的内切核酸酶的优化核酸分子，宿主细胞和包含一种或多种核酸分子的植物 进一步公开。