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    ANTIVIRAL DRUG
    7.
    发明申请
    ANTIVIRAL DRUG 审中-公开
    抗病毒药物

    公开(公告)号：US20170073442A1

    公开(公告)日：2017-03-16

    申请号：US15122074

    申请日：2015-02-26

    申请人： Shoichi SHIROTAKE

    发明人： Shoichi SHIROTAKE ,  Syun-ichirou OSHIMA ,  Masayuki IMAJOH

    IPC分类号： C08F122/32 ,  A61K31/785 ,  A01N37/34

    CPC分类号： C08F122/32 ,  A01N37/34 ,  A01N37/44 ,  A61K9/1635 ,  A61K31/78 ,  A61K31/785 ,  A61K47/18 ,  A61K47/20 ,  A61K47/22 ,  A61K47/24 ,  A61K47/26 ,  A61K47/36 ,  A01N25/10 ,  A01N25/34

    摘要： Novel antiviral means is disclosed. The antiviral agent of the present invention comprises as an effective ingredient particles having a particle diameter of not more than 5 μm, wherein said particles are polymer particles whose repeat unit comprises a structure represented by a particular general formula, and wherein said particles do not contain an antiviral active component. The polymer particles are preferably cyanoacrylate polymer particles. The antiviral agent of the present invention shows adhesiveness to the surface (especially envelope) of virus particles, and destroys a normal virus particle structure to reduce or eliminate infectivity of the virus particles. Sanitary articles such as masks comprising the antiviral agent of the present invention can exert an excellent effect on prevention of infection with viruses such as influenza virus that occurs through droplet infection or airborne infection.

    摘要翻译： 公开了新型抗病毒手段。 本发明的抗病毒剂包含作为有效成分的粒径不大于5μm的颗粒，其中所述颗粒是其重复单元包含由特定通式表示的结构的聚合物颗粒，并且其中所述颗粒不含 抗病毒活性成分。 聚合物颗粒优选为氰基丙烯酸酯聚合物颗粒。 本发明的抗病毒剂显示出与病毒颗粒的表面（尤其是包膜）的粘附性，并破坏正常的病毒颗粒结构以减少或消除病毒颗粒的感染性。 包含本发明的抗病毒剂的面罩等卫生制品能够对通过液滴感染或空气传播感染而发生的流感病毒等病毒感染的预防效果良好。

    Protein-cyanoacrylate nanoparticles that improve wetting property of materials
    8.
    发明授权
    Protein-cyanoacrylate nanoparticles that improve wetting property of materials 有权
    蛋白质 - 氰基丙烯酸酯纳米粒子，改善材料的润湿性能

    公开(公告)号：US09062151B1

    公开(公告)日：2015-06-23

    申请号：US13768069

    申请日：2013-02-15

    申请人： The United States of America as represented by the Secretary of Agriculture

    发明人： Sanghoon Kim

    IPC分类号： C08L77/00 ,  C08G69/10

    CPC分类号： C08G69/10 ,  C08F122/32

    摘要： Nanoparticles which are comprised of a protein-poly(alkyl-cyanoacrylate) or protein-poly(alkenyl-cyanoacrylate) copolymer may be used as a surface treatment to alter the wetting properties of a variety of different materials. The nanoparticles are produced by the method comprising: a) providing a solution of a protein in an aqueous organic solvent mixture such as an acidified aqueous alcohol; b) adding an alkyl- or alkenyl-cyanoacrylate and mixing under conditions effective to react with the protein and produce the nanoparticles comprised of a protein-poly(alkyl-cyanoacrylate) or protein-poly(alkenyl-cyanoacrylate) copolymer; and c) recovering the nanoparticles. The nanoparticles are amphiphilic, and may alter the surface-wetting properties of an object when applied onto the surface thereof. When applied onto hydrophobic surfaces, the nanoparticles render the surfaces hydrophilic.

    摘要翻译： 由蛋白质 - 聚（烷基 - 氰基丙烯酸酯）或蛋白质 - 聚（链烯基 - 氰基丙烯酸酯）共聚物组成的纳米颗粒可用作表面处理以改变各种不同材料的润湿性能。 通过以下方法制备纳米颗粒：a）提供蛋白质在含水有机溶剂混合物如酸化的含水醇中的溶液; b）加入氰基丙烯酸烷基酯或烯基酯并在有效与蛋白质反应的条件下混合并产生由蛋白质 - 聚（烷基 - 氰基丙烯酸酯）或蛋白质 - 聚（链烯基 - 氰基丙烯酸酯）共聚物组成的纳米粒子; 和c）回收纳米颗粒。 纳米颗粒是两亲性的，并且当施加到其表面上时可以改变物体的表面润湿性质。 当应用于疏水性表面时，纳米颗粒使表面亲水。

    CURABLE COMPOSITION
    10.
    发明公开
    CURABLE COMPOSITION 审中-公开

    公开(公告)号：US20230391903A1

    公开(公告)日：2023-12-07

    申请号：US18248948

    申请日：2021-10-13

    申请人： TOAGOSEI CO., LTD.

    发明人： Kei KONDO ,  Erika ISSHIKI ,  Kenichi ISHIZAKI ,  Eiichi OKAZAKI

    IPC分类号： C08F122/32 ,  C09J4/00 ,  C09J7/38

    CPC分类号： C08F122/32 ,  C09J4/00 ,  C09J7/385 ,  C09J2301/302 ,  C09J2433/00

    摘要： A curable composition, including a 2-cyanoacrylate compound represented by Formula (1), in which a storage modulus of a cured product of the curable composition at 23° C. is from 1.0×104 Pa to 1.0×108 Pa and in which, in Formula (1), each L1 independently represents a linear or branched alkylene group having 2 to 6 carbon atoms which may have a sub stituent, p represents an integer from 2 to 8, and R1 represents an linear or branched alkyl group, an aryl group, an alkenyl group or an alkynyl group having 1 to 8 carbon atoms which may have a substituent.