知搜-全球专利检索

  1. 登录
  2. 注册

搜索结果

74 条记录 (耗时 0.032 秒)

    Nitrone compounds and their use in personal care
    2.
    发明授权
    Nitrone compounds and their use in personal care 有权

    公开(公告)号：US09730874B2

    公开(公告)日：2017-08-15

    申请号：US15310513

    申请日：2015-05-07

    申请人： Dow Global Technologies LLC

    发明人： George David Green ,  Raymond J. Swedo

    IPC分类号： A61K8/40 ,  A61K8/41 ,  A61Q19/08 ,  C07C291/02

    CPC分类号： C07C251/30 ,  A61K8/40 ,  A61K8/41 ,  A61K8/416 ,  A61Q19/00 ,  A61Q19/08 ,  C07C291/02

    摘要： Provided are compounds and compositions thereof that are useful as antioxidants in personal care formulations. The compounds are of the Formula I: wherein R1, R2, R3, R4, and R5 are independently H, —OH, C1-C6 alkoxy, —COOH, —COO−M+ or —O−M+, where M+ is a sodium, potassium, or ammonium ion, and R6, R7, R8, R9, and R10, are independently H, —OH, C1-C6 alkoxy, —COOH, —COO−M+ or —O−M+, where M+ is a sodium, potassium, or ammonium ion, or a substituent of Formula II: wherein R11, R12, R13, R14, and R15 are independently H, —OH, C1-C6 alkoxy, —COOH, —COO−M+ or —O−M+, where M+ is a sodium, potassium, or ammonium ion, provided that one of R6, R7, R8, R9, and R10 is a substituent of Formula II.

    Near infrared fluorogen and fluorescent activating proteins for in vivo imaging and live-cell biosensing
    3.
    发明授权
    Near infrared fluorogen and fluorescent activating proteins for in vivo imaging and live-cell biosensing 有权
    近红外荧光和荧光激活蛋白，用于体内成像和活细胞生物传感

    公开(公告)号：US09023998B2

    公开(公告)日：2015-05-05

    申请号：US13920775

    申请日：2013-06-18

    申请人： Carnegie Mellon University

    发明人： Subhasish K. Chakraborty ,  Mingrui Zhang ,  Alan S. Waggoner

    IPC分类号： C07K16/44 ,  G01N21/64 ,  A61K49/00 ,  C07D207/46 ,  C07C309/18 ,  C07C251/30

    CPC分类号： G01N21/6486 ,  A61K49/0021 ,  A61K49/0023 ,  C07C251/30 ,  C07C309/18 ,  C07D207/46 ,  C07K16/44 ,  C07K2317/515 ,  C09B23/0008 ,  C09B23/04 ,  C09B23/06 ,  C09B23/08

    摘要： Tissue slices and whole organisms offer substantial challenges to fluorescence imaging. Autofluorescence and absorption via intrinsic chromophores, such as flavins, melanin, and hemoglobins, confound and degrade output from all fluorescent tags. An “optical window,” farther red than most autofluorescence sources and in a region of low hemoglobin and water absorbance, lies between 650 and 900 nm. This valley of relative optical clarity is an attractive target for fluorescence-based studies within tissues, intact organs, and living organisms. Novel fluorescent tags were developed herein, based upon a genetically targeted fluorogen activating protein and cognate fluorogenic dye that yields emission with a peak at 733 nm exclusively when complexed as a “fluoromodule”. This tool improves substantially over previously described far-red/NIR fluorescent proteins in terms of brightness, wavelength, and flexibility by leveraging the flexibility of synthetic chemistry to produce novel chromophores.

    摘要翻译： 组织切片和整个生物体对荧光成像提供了重大挑战。 通过内在发色团（如黄素，黑色素和血红蛋白）的自发荧光和吸收会混淆和降解所有荧光标记的输出。 “光学窗口”比大多数自发荧光源更红，在低血红蛋白和吸水度的区域中位于650和900nm之间。 相对光学透明度的这个谷物是组织，完整器官和活生物体内基于荧光的研究的有吸引力的目标。 本文开发了基于遗传靶向荧光素激活蛋白和同源荧光染料的新型荧光标记，其在733nm处产生具有峰值的发射，当作为“荧光团”复合时。 通过利用合成化学的灵活性来生产新颖的发色团，该工具在亮度，波长和灵活性方面基本上优于之前描述的远红/ NIR荧光蛋白。

    NOVEL COMPOUND, OPTICAL FILTER AND OPTICAL RECORDING MATERIAL USING THE SAME
    4.
    发明申请
    NOVEL COMPOUND, OPTICAL FILTER AND OPTICAL RECORDING MATERIAL USING THE SAME 失效
    新型化合物，光学过滤器和光学记录材料

    公开(公告)号：US20090137800A1

    公开(公告)日：2009-05-28

    申请号：US12299052

    申请日：2007-03-05

    申请人： Satoshi Yanagisawa

    发明人： Satoshi Yanagisawa

    IPC分类号： C07C251/30 ,  C07D207/20 ,  C07C255/61 ,  C07D401/14 ,  C07D401/06 ,  C07D413/14 ,  C07D403/06

    CPC分类号： C07C251/30 ,  C07D207/20 ,  C07D209/14 ,  C07D213/74 ,  C07D401/14 ,  C07D413/14 ,  C09B11/02 ,  C09B23/06 ,  G02B5/223

    摘要： A compound represented by the following general formula (I), wherein ring A and ring B each independently represent a benzene, naphthalene, or heterocyclic ring which may be substituted; R1 and R2 each independently represent an alkyl group having 1 to 8 carbon atoms which may be substituted; R1 and R2 may be linked together to form a ring; a methylene group of the alkyl group having 1 to 8 carbon atoms may be replaced by —O— or —CH═CH—; Anq- represents a q-valent anion, where q is 1 or 2; p represents a coefficient to keep the charge neutral.

    摘要翻译： 由以下通式（I）表示的化合物，其中环A和环B各自独立地表示可被取代的苯，萘或杂环; R 1和R 2各自独立地表示可以被取代的具有1〜8个碳原子的烷基; R1和R2可以连接在一起形成环; 具有1-8个碳原子的烷基的亚甲基可被-O-或-CH-CH-取代; Anq-表示q价阴离子，其中q为1或2; p表示使电荷保持中性的系数。

    Method of producing near-infrared absorbing dye compound
    5.
    发明申请
    Method of producing near-infrared absorbing dye compound 有权
    生产近红外吸收染料化合物的方法

    公开(公告)号：US20080221355A1

    公开(公告)日：2008-09-11

    申请号：US11514181

    申请日：2006-09-01

    申请人： Keizo Kimura ,  Tomohito Masaki ,  Osamu Uchida ,  Katsuyoshi Yamakawa

    发明人： Keizo Kimura ,  Tomohito Masaki ,  Osamu Uchida ,  Katsuyoshi Yamakawa

    IPC分类号： C07C211/54

    CPC分类号： C09B53/02 ,  C07C249/02 ,  G11B7/246 ,  C07C251/30

    摘要： A method of producing a near-infrared absorbing dye compound, useful for image forming materials, infrared heat-sensitive recording devices, optical film materials, and the like, containing a process of reacting a compound represented by formula (I) with peroxomonosulfuric acid or its salt. wherein R111, R112, R121, R122, R131, R132, R141 and R142 each independently represent a hydrogen atom, an aliphatic group or an aromatic group; R103, R113, R123, R133 and R143 each independently represent a substituent; and n103, n113, n123, n133 and n143 each independently denote an integer from 0 to 4.

    摘要翻译： 一种制造用于成像材料的红外吸收染料化合物的方法，红外热敏记录装置，光学膜材料等，其包含使式（I）表示的化合物与碳酸二氢酸反应的方法或 它的盐 其中R 111，R 112，R 121，R 122，R 131， R 132，R 141和R 142各自独立地表示氢原子，脂族基团或芳族基团; R 103，R 123，R 123，R 123，R 123和/或每个 独立地表示取代基; 和n 103，n 113，n 123，n 133和n 143， 各自独立地表示0〜4的整数。

    Fluorine compound and fluorinating agent comprising the compound
    6.
    发明申请
    Fluorine compound and fluorinating agent comprising the compound 失效
    氟化合物和包含该化合物的氟化剂

    公开(公告)号：US20040073065A1

    公开(公告)日：2004-04-15

    申请号：US10433412

    申请日：2003-06-04

    发明人： Toshio Hidaka ,  Norio Fushimi ,  Takafumi Yoshimura ,  Takeshi Kawai

    IPC分类号： C07C019/08 ,  C07F009/02

    CPC分类号： C07F9/54 ,  C07B39/00 ,  C07C17/16 ,  C07C17/18 ,  C07C211/29 ,  C07C251/30 ,  C07C271/20 ,  C07F9/5004 ,  Y02P20/582

    摘要： A fluorine compound represented by Formula (1) is provided. The above fluorine compound is effective for introducing a fluorine atom into a compound having an active group such as an oxygen-containing functional group, and it can be used for uses of surface treatment, cleaning and coating. Further, after the fluorination reaction, the above compound is recovered and can be reused as a starting material for producing the above fluorine compound, and it is useful for various fluorination processes. 1 (wherein X represents a nitrogen or phosphorus atom; R0, R1, and R2 represent hydrogen, an alkyl group or aryl group which may have a substituent, and they each may be the same or different; and R0, R1, and R2 may be combined with each other to form a ring).

    摘要翻译： 提供由式（1）表示的氟化合物。 上述氟化合物有效地将氟原子引入具有活性基团的化合物如含氧官能团，并且其可用于表面处理，清洁和涂覆的用途。 此外，在氟化反应之后，回收上述化合物，可以重复使用作为制备上述氟化合物的原料，可用于各种氟化处理。 （其中X表示氮或磷原子; R 0，R 1和R 2表示氢，可以具有取代基的烷基或芳基，它们各自可以相同或不同; R 0，R 1和R 2可以是 结合起来形成一个戒指）。