专利检索 cpc:"B01F23/4144" 第 1 页

1.

发明公开
FLOW FOCUSING TYPE ONE-STEP DOUBLE EMULSION DROPLET PARALLEL GENERATION DEVICE AND METHOD 审中-公开

公开(公告)号：US20230311087A1

公开(公告)日：2023-10-05

申请号：US18207655

申请日：2023-06-08

申请人： Guangzhou University

发明人： Fan Jiang , Haitao Huang , Meirong Chen , Haoxiang Huang , Yuqin Huang , Ju Yan

IPC分类号： B01J13/04 , B01J13/10 , B01L3/00 , B01F23/41 , B01F33/3011

CPC分类号： B01J13/04 , B01J13/10 , B01L3/502746 , B01F23/4105 , B01F23/4144 , B01F23/4143 , B01F33/3011 , B01L2400/086 , B01L2200/0636 , B01L2300/0861 , B01L2400/0406

摘要： A flow focusing type one-step double emulsion droplet parallel generation device and method. The device comprises a fluid injection module, a liquid droplet generation module, a liquid droplet surface solidification module and a liquid droplet collection module, wherein the fluid injection module is used for conveying fluid of each phase to the liquid droplet generation module; and the liquid droplet generation module comprises a fluid distribution functional area, a liquid droplet preparation functional area and an auxiliary functional arca, wherein the liquid droplet distribution functional area is used for conveying the fluid of each phase into a channel of the fluid of each phase corresponding to the liquid droplet preparation functional area, and the fluid of each phase is gathered at the same point in a flow focusing structure and then is broken, and a fluid of an outer phase covers the fluid of the middle phase.

2.

发明公开
FLOW FOCUSING DEVICES, SYSTEMS, AND METHODS FOR HIGH THROUGHPUT DROPLET FORMATION 审中-公开

公开(公告)号：US20230278038A1

公开(公告)日：2023-09-07

申请号：US18177562

申请日：2023-03-02

申请人： 10x Genomics, Inc.

发明人： Mohammad RAHIMI LENJI , Yiran ZHANG , Francis MARCOGLIESE , Tobias Daniel WHEELER , Rajiv BHARADWAJ

IPC分类号： B01L3/00 , B01F23/41 , B01F33/3011

CPC分类号： B01L3/502792 , B01F23/4144 , B01F33/3011 , B01F23/4105 , B01L2300/0867 , B01L2200/16 , B01L2200/0673 , B01L2300/0816

摘要： Devices, systems, and their methods of use, for generating and collecting droplets are provided. Devices use flow focusing arrangements of channels to produce droplets. The invention further provides multiplex devices that increase droplet formation.

3.

发明授权
Manufacturing of bupivacaine multivesicular liposomes 有权

公开(公告)号：US11819574B2

公开(公告)日：2023-11-21

申请号：US17719716

申请日：2022-04-13

申请人： Pacira Pharmaceuticals, Inc.

发明人： Jeffrey S. Hall , David J. Turnbull , John J. Grigsby, Jr. , Soroush M. Ardekani , Kathleen D. A. Los

IPC分类号： A61K9/127 , A61K31/451 , B01D61/14 , B01F23/80 , B01F23/41 , B01F101/22

CPC分类号： A61K9/1277 , A61K31/451 , B01D61/146 , B01D61/147 , B01F23/4105 , B01F23/808 , B01D2315/10 , B01D2315/16 , B01F23/4144 , B01F23/4145 , B01F2101/22 , B01F2215/044 , B01F2215/0477 , B01F2215/0481

摘要： Embodiments of the present application relate to batches of bupivacaine multivesicular liposomes (MVLs) prepared by a commercial manufacturing process using independently operating dual tangential flow filtration modules.

4.

发明授权
Microfluidic device and a method for provision of double emulsion droplets 有权

公开(公告)号：US11779923B2

公开(公告)日：2023-10-10

申请号：US16770135

申请日：2018-12-04

申请人： SAMPLIX APS

发明人： Thomas Kvist , Esben Bjørn Madsen , Solène Cherre , Marie Just Mikkelsen

IPC分类号： B01L3/00 , B01F23/41 , B01F33/3011 , B01F33/301 , B01F33/30 , B01F101/23

CPC分类号： B01L3/502784 , B01F23/4105 , B01F33/3011 , B01F33/3017 , B01L3/502707 , B01L3/502715 , B01F23/4143 , B01F23/4144 , B01F2101/23 , B01L2200/028 , B01L2200/06 , B01L2200/0673 , B01L2200/12 , B01L2200/141 , B01L2300/0681 , B01L2300/0867

摘要： The present invention relates to a microfluidic device, a method for manufacturing a microfluidic device, and a method for provision of double emulsion droplets using a microfluidic device. Furthermore, the present invention relates to an assembly configured to supply pressure to the microfluidic device for provision of double emulsion droplets. Furthermore, the present invention relates to a kit comprising a plurality of microfluidic devices and a plurality of fluids configured for use with the microfluidic device for provision of double emulsion droplets. The microfluidic device comprises a transfer conduit comprising a first transfer conduit part having a first affinity for water; and a collection conduit comprising a first collection conduit part having a second affinity for water being different from the first affinity for water. A well section and a microfluidic section of the microfluidic device are fixedly connected to each other.

5.

发明授权
Device and method for generating droplets 有权

公开(公告)号：US11872533B2

公开(公告)日：2024-01-16

申请号：US16498002

申请日：2018-03-22

申请人： ETH ZURICH

发明人： André R. Studart , Alessandro Ofner , Pascal Schwendimann

IPC分类号： B01F5/04 , B01F3/08 , B01F25/314 , B01L3/02 , B01L3/00 , B05B1/14 , B01F23/41 , B01F33/302

CPC分类号： B01F25/31425 , B01F23/41 , B01F33/3021 , B01L3/0241 , B01L3/502746 , B05B1/14 , B01F23/4144 , B01F2215/0431 , B01L2300/0861 , B01L2400/02 , B01L2400/086

摘要： The invention relates to a device (1) for generating droplets (30) comprising a plurality of channels (20), wherein each channel (20) extends from an inlet (201) along a respective longitudinal axis (L) to an outlet (202), wherein said device (1) comprises a plurality of layers (10) of a substrate material arranged in a stack (100), wherein each layer (10) comprises a first side (101) and a second side (102) facing away from each other, and wherein said first side (101) of each layer (10) comprises a plurality of grooves (103), wherein said channels (20) are formed by said grooves (103) of said first side (101) of a respective layer (10) of said stack (100) and said second side (102) of a respective adjacent layer (10) of said stack (100). The invention further relates to a method for generating droplets (30) and a fabrication method of the device (1).