公开(公告)号：US20190247662A1

公开(公告)日：2019-08-15

申请号：US16209301

申请日：2018-12-04

申请人： Neuroenhancement Lab, LLC

发明人： Alexander Poltroak

IPC分类号： A61N1/36 ,  A61B5/04 ,  A61B5/0484 ,  A61N1/05 ,  A61N1/04 ,  A61N1/20 ,  A61N2/00 ,  A61B6/03 ,  A61B5/00 ,  A61N1/372 ,  A61N1/375

CPC分类号： A61N1/36092 ,  A61B5/0051 ,  A61B5/0053 ,  A61B5/04001 ,  A61B5/04009 ,  A61B5/04842 ,  A61B5/04845 ,  A61B5/04847 ,  A61B6/037 ,  A61N1/0456 ,  A61N1/0534 ,  A61N1/0551 ,  A61N1/20 ,  A61N1/36025 ,  A61N1/36046 ,  A61N1/36053 ,  A61N1/37205 ,  A61N1/37512 ,  A61N2/006 ,  G01R33/4806 ,  G01T1/2985

摘要： A method of facilitating a skill learning process or improving performance of a task, comprising: determining a brainwave pattern reflecting neuronal activity of a skilled subject while engaged in a respective skill or task; processing the determined brainwave pattern with at least one automated processor; and subjecting a subject training in the respective skill or task to brain entrainment by a stimulus selected from the group consisting of one or more of a sensory excitation, a peripheral excitation, a transcranial excitation, and a deep brain stimulation, dependent on the processed temporal pattern extracted from brainwaves reflecting neuronal activity of the skilled subject.

公开(公告)号：US09826914B2

公开(公告)日：2017-11-28

申请号：US14254933

申请日：2014-04-17

申请人： Elminda Ltd.

发明人： Goded Shahaf ,  Amir B. Geva ,  Tomer Carmeli ,  Noga Pinchuk ,  Israel Tauber ,  Amit Reches ,  Guy Ben-Bassat ,  Ayelet Kanter ,  Urit Gordon

IPC分类号： A61B5/04 ,  A61B5/0476 ,  A61B5/0482 ,  A61B5/00

CPC分类号： A61B5/04012 ,  A61B5/04009 ,  A61B5/0476 ,  A61B5/0482 ,  A61B5/7203 ,  A61B5/726 ,  A61B5/742

摘要： A method for functional analysis of neurophysiological data by decomposing neurophysiological data and EEG signal to form a plurality of signal features. The signal features may then optionally be analyzed to determined one or more patterns.

公开(公告)号：US09451883B2

公开(公告)日：2016-09-27

申请号：US13725893

申请日：2012-12-21

申请人： THE REGENTS OF THE UNIVERSITY OF CALIFORNIA

发明人： Jack L. Gallant ,  Thomas Naselaris ,  Kendrick Kay ,  Ryan Prenger

IPC分类号： A61B5/04 ,  A61B5/00 ,  G06K9/00 ,  A61B6/03 ,  A61B6/00 ,  A61B5/0484 ,  A61B5/055

CPC分类号： A61B5/0042 ,  A61B5/0075 ,  A61B5/04001 ,  A61B5/04009 ,  A61B5/04012 ,  A61B5/04017 ,  A61B5/04842 ,  A61B5/04845 ,  A61B5/055 ,  A61B5/725 ,  A61B5/726 ,  A61B6/037 ,  A61B6/501 ,  A61B6/5217 ,  G06K9/00536

摘要： Decoding and reconstructing a subjective perceptual or cognitive experience is described. A first set of brain activity data produced in response to a first brain activity stimulus is acquired from a subject using a brain imaging device. An encoding model is used to convert the brain activity data into a corresponding set of predicted response values. A second set of brain activity data produced in response to a second brain activity stimulus is acquired from a subject and decoded using a decoding distribution derived from the encoding model, and the probability the second set of brain activity data corresponds to said predicted response values is determined. The second set of brain activity stimuli is then reconstructed based on the probability of correspondence between the second set of brain activity data and the predicted response values.

摘要翻译： 描述并重建主观感知或认知经验。 使用脑成像装置从受试者获得响应于第一脑活动刺激产生的第一组脑活动数据。 编码模型用于将大脑活动数据转换成相应的一组预测响应值。 从受试者获取响应于第二脑活动刺激产生的第二组脑活动数据，并使用从编码模型导出的解码分布进行解码，并且第二组脑活动数据对应于所述预测响应值的概率为 决心。 然后基于第二组脑活动数据与预测响应值之间的对应概率重建第二组脑活动刺激。

公开(公告)号：US09339227B2

公开(公告)日：2016-05-17

申请号：US13701252

申请日：2011-06-17

申请人： Ryan D'arcy ,  Donald F. Weaver ,  Sujoy Ghosh Hajra ,  Careesa Liu ,  Lauren Sculthorpe-Petley

发明人： Ryan D'arcy ,  Donald F. Weaver ,  Sujoy Ghosh Hajra ,  Careesa Liu ,  Lauren Sculthorpe-Petley

IPC分类号： A61B5/05 ,  A61B5/00 ,  A61B5/0484 ,  A61B5/16 ,  A61B5/04

CPC分类号： A61B5/4842 ,  A61B5/04009 ,  A61B5/04012 ,  A61B5/0484 ,  A61B5/04845 ,  A61B5/165 ,  A61B5/7246

摘要： A method for analysis of the extent of conscious awareness and likelihood of recovery of a patient includes the steps of applying to the patient a sensory stimulus sequence which is typically auditory; carrying out an EEG to generate waveform signals to record changes in the electromagnetic fields generated by the patient's neural activity; using software provided in a processor to process the waveform signals in order to locate waveform peaks, identify the event-related potential (ERP) components obtained in the waveform and to obtain quantitative measures of those components; and using the software to generate and communicate scores indicative of the extent of conscious awareness and likelihood of recovery of the patient.

摘要翻译： 用于分析意识的程度和患者恢复的可能性的方法包括以下步骤：向患者施加通常是听觉的感觉刺激序列; 进行EEG生成波形信号，记录患者神经活动产生的电磁场变化; 使用处理器中提供的软件来处理波形信号以定位波形峰值，识别在波形中获得的事件相关电位（ERP）分量，并获得这些分量的定量测量; 并使用该软件产生和传达表示患者自觉意识程度和恢复可能性的分数。

公开(公告)号：US20150327813A1

公开(公告)日：2015-11-19

申请号：US14814364

申请日：2015-07-30

申请人： Chi Yung Fu

发明人： Chi Yung Fu

IPC分类号： A61B5/00 ,  A61B5/0478 ,  A61N2/02 ,  A61N2/00 ,  A61B5/0484 ,  A61B5/0402 ,  A61N5/10 ,  A61N5/02 ,  A61N1/40 ,  A61N7/00 ,  A61B5/04 ,  A61N1/36

CPC分类号： A61B5/0476 ,  A61B5/0042 ,  A61B5/0075 ,  A61B5/04009 ,  A61B5/04012 ,  A61B5/0402 ,  A61B5/0478 ,  A61B5/0484 ,  A61B5/165 ,  A61B5/4836 ,  A61B5/6803 ,  A61B5/7203 ,  A61B5/726 ,  A61B5/7264 ,  A61B2560/0214 ,  A61B2562/046 ,  A61B2562/14 ,  A61B2576/026 ,  A61N1/0408 ,  A61N1/0456 ,  A61N1/0476 ,  A61N1/0526 ,  A61N1/36014 ,  A61N1/36021 ,  A61N1/36025 ,  A61N1/40 ,  A61N2/006 ,  A61N2/008 ,  A61N2/02 ,  A61N5/02 ,  A61N5/10 ,  A61N7/00 ,  G06F19/00 ,  G06F19/3481 ,  G16H50/20

摘要： A signal processing method and system combines multi-scale decomposition, such as wavelet, pre-processing together with a compression technique, such as an auto-associative artificial neural network, operating in the multi-scale decomposition domain for signal denoising and extraction. All compressions are performed in the decomposed domain. A reverse decomposition such as an inverse discrete wavelet transform is performed on the combined outputs from all the compression modules to recover a clean signal back in the time domain. A low-cost, non-drug, non-invasive, on-demand therapy braincap system and method are pharmaceutically nonintrusive to the body for the purpose of disease diagnosis, treatment therapy, and direct mind control of external devices and systems. It is based on recognizing abnormal brainwave signatures and intervenes at the earliest moment, using magnetic and/or electric stimulations to reset the brainwaves back to normality. The feedback system is self-regulatory and the treatment stops when the brainwaves return to normal. The braincap contains multiple sensing electrodes and microcoils; the microcoils are pairs of crossed microcoils or 3-axis triple crossed microcoils.

摘要翻译： 一种信号处理方法和系统将诸如小波，预处理的多尺度分解与诸如自相关人造神经网络的压缩技术相结合，在多尺度分解域中操作用于信号去噪和提取。 所有的压缩都是在分解域中进行的。 对来自所有压缩模块的组合输出执行反向分解，例如反向离散小波变换，以在时域中恢复干净的信号。 低成本，非药物，非侵入性，按需治疗脑盖系统和方法是药物非侵入性的身体，用于疾病诊断，治疗治疗和外部设备和系统的直接心理控制。 它基于识别异常脑波特征并在最早的时刻进行干预，使用磁刺激和/或电刺激将脑电波重置为正常。 反馈系统是自我监管的，治疗在脑电波恢复正常时停止。 脑盖包含多个感测电极和微线圈; 微线圈是交叉的微线圈或3轴三重交叉微线圈的对。

公开(公告)号：US20150320591A1

公开(公告)日：2015-11-12

申请号：US14707268

申请日：2015-05-08

申请人： Scion NeuroStim, LLC

发明人： Lanty L. Smith ,  Lesco L. Rogers ,  Robert D. Black

IPC分类号： A61F7/12 ,  A61B6/03 ,  A61B8/08 ,  A61B5/0484 ,  A61B8/06 ,  A61B5/04 ,  A61B5/00

CPC分类号： A61B5/6817 ,  A61B5/0059 ,  A61B5/04009 ,  A61B5/0484 ,  A61B5/4023 ,  A61B6/037 ,  A61B8/06 ,  A61B8/488 ,  A61F7/0085 ,  A61F7/12 ,  A61F2007/0005 ,  A61F2007/0054 ,  A61F2007/0056 ,  A61F2007/0058 ,  A61F2007/0059 ,  A61F2007/0086 ,  A61F2007/0096

摘要： An in-ear stimulation system for administering caloric stimulation to the ear canal of a subject includes (a) a conduit configured to deliver a fluid to calorically stimulate an ear canal of a subject; and (b) a fluid control unit comprising a controller configured to control a flow of the fluid to the conduit and/or to control a caloric profile of the fluid such that a temperature of the fluid changes through time when the fluid is being delivered to the ear canal via the conduit.

摘要翻译： 用于对受试者的耳道施加热量刺激的入耳式刺激系统包括（a）配置成输送流体以热量刺激受试者的耳道的导管; 和（b）流体控制单元，其包括控制器，所述控制器被配置为控制流体流向管道和/或控制流体的热量轮廓，使得流体的温度随着流体被输送到时间而变化 耳道通过导管。

公开(公告)号：US20150208934A1

公开(公告)日：2015-07-30

申请号：US14163142

申请日：2014-01-24

申请人： Genevieve Sztrubel ,  Arnaldo Mayer

发明人： Genevieve Sztrubel ,  Arnaldo Mayer

IPC分类号： A61B5/04 ,  A61B5/00

CPC分类号： A61B5/04001 ,  A61B5/0048 ,  A61B5/04009 ,  A61B5/4893

摘要： The invention relates to a method and apparatus for neural tissue detection carried out using the Neural Tissue Detector (NTD), which is the apparatus that embodies the hardware aspect of the invention. The NTD enables neural tissue detection by stimulating a small tissue area and by measuring possible occurrences of induced response from neural tissue, if neural tissue is present in said small stimulated tissue area. The information gathered by the measurement provides a real-time assessment of the nature of the tissue which is targeted by the NTD. The invention is applicable to all types of neural tissues, including motor, and/or sensory and/or other types of neural tissues. The invention offers particular advantages in robot based surgical procedures or intravascular catheter based procedures but can also be used for manual surgery, according to different specific embodiments.

摘要翻译： 本发明涉及使用神经组织检测器（NTD）进行神经组织检测的方法和装置，其是体现本发明的硬件方面的装置。 如果神经组织存在于所述小刺激组织区域中，NTD通过刺激小的组织区域和通过测量来自神经组织的诱导反应的可能发生来启动神经组织检测。 通过测量收集的信息可以对NTD所针对的组织的性质进行实时评估。 本发明可应用于所有类型的神经组织，包括运动，和/或感觉和/或其他类型的神经组织。 根据不同的具体实施方式，本发明在基于机器人的外科手术或基于血管内导管的程序中具有特别的优点，但是也可以用于手动手术。

公开(公告)号：US20140058528A1

公开(公告)日：2014-02-27

申请号：US13695631

申请日：2011-05-05

申请人： Jose L. Contreras-Vidal ,  Trent J. Bradberry ,  Rodolphe J. Gentili ,  Harshavardhan Agashe

发明人： Jose L. Contreras-Vidal ,  Trent J. Bradberry ,  Rodolphe J. Gentili ,  Harshavardhan Agashe

IPC分类号： A61F2/72 ,  A61B5/04 ,  A61B5/0478 ,  A61B5/0484

CPC分类号： A61F2/72 ,  A61B5/04009 ,  A61B5/04012 ,  A61B5/0478 ,  A61B5/04842 ,  A61B5/0496 ,  G06F3/013 ,  G06F3/015

摘要： A noninvasive brain computer interface (BCI) system includes an electroencephalography (EEG) electrode array configured to acquire EEG signals generated by a subject. The subject observes movement of a stimulus. A computer is coupled to the EEG electrode array and configured to collected and process the acquired EEG signals. A decoding algorithm is used that analyzes low-frequency (delta band) brain waves in the time domain to continuously decode neural activity associated with the observed movement.

摘要翻译： 无创脑计算机接口（BCI）系统包括被配置成获取被检者产生的EEG信号的脑电图（EEG）电极阵列。 受试者观察到刺激的运动。 计算机耦合到EEG电极阵列并且被配置为收集并处理获取的EEG信号。 使用解码算法来分析时域中的低频（delta band）脑波，以连续解码与观察到的运动相关的神经活动。

公开(公告)号：US20130085678A1

公开(公告)日：2013-04-04

申请号：US13442627

申请日：2012-04-09

申请人： Edward K.Y. Jung ,  Eric C. Leuthardt ,  Royce A. Levien ,  Robert W. Lord ,  Mark A. Malamud ,  John D. Rinaldo, JR. ,  Lowell I. Wood, JR.

发明人： Edward K.Y. Jung ,  Eric C. Leuthardt ,  Royce A. Levien ,  Robert W. Lord ,  Mark A. Malamud ,  John D. Rinaldo, JR. ,  Lowell I. Wood, JR.

IPC分类号： G06F19/26

CPC分类号： G16B45/00 ,  A61B5/04009 ,  A61B5/04842 ,  A61B5/0533 ,  A61B5/055 ,  A61B5/1455 ,  A61B5/16 ,  A61B5/167 ,  A61B5/4064 ,  A61B5/441 ,  A61B5/726 ,  A61B5/744 ,  A61B2503/12 ,  G06Q10/0637 ,  G06Q30/02 ,  G06Q30/0601

摘要： Avatars, methods, apparatuses, computer program products, devices and systems are described that carry out presenting to at least one member of a population a plurality of avatars associated with at least one instance of media content; measuring at least one physiologic activity of the at least one member of the population, the at least one physiologic activity proximate to at least one presented avatar among the plurality of avatars associated with at least one instance of media content; associating the at least one physiologic activity with at least one mental state; and identifying at least one instance of media content based on the at least one mental state.

摘要翻译： 描述了化身，方法，设备，计算机程序产品，设备和系统，其向群体的至少一个成员呈现与媒体内容的至少一个实例相关联的多个化身; 测量所述群体的至少一个成员的至少一个生理活动，所述至少一个生理活动接近于与所述媒体内容的至少一个实例相关联的所述多个化身中的至少一个呈现的化身; 将所述至少一个生理活动与至少一个精神状态相关联; 以及基于所述至少一个精神状态来识别媒体内容的至少一个实例。

公开(公告)号：US20120116725A1

公开(公告)日：2012-05-10

申请号：US13383939

申请日：2010-07-14

申请人： Ludger Klinkenbusch

发明人： Ludger Klinkenbusch

IPC分类号： G06F15/00

CPC分类号： G01R29/10 ,  A61B5/04004 ,  A61B5/04009 ,  A61B5/0484 ,  A61B5/6814

摘要： The disclosure relates to a method for reconstructing the source of an electromagnetic field. Firstly, a measurement space separate from the source is selected so that the measurement space is connected to the source via a magnetically homogeneous spatial region. Measured values of the electromagnetic field emitted by the source are recorded on the surface of the measurement space so that the electromagnetic field in the measurement space can be uniquely determined in the context of an error bound determined by the discreteness of the measured values. A mathematical model of the electromagnetic source is developed which has a multiplicity of unknowns, and a system of equations is set up that relates the unknowns of the model to the measured values. The system of equations is solved in order to determine the characteristics of the electromagnetic source. The disclosure also relates to an arrangement for carrying out the method.

摘要翻译： 本发明涉及重建电磁场源的方法。 首先，选择与源分离的测量空间，使得测量空间通过磁性均匀的空间区域连接到源极。 由源发出的电磁场的测量值被记录在测量空间的表面上，使得测量空间中的电磁场可以在由测量值的离散性确定的误差界限的上下文中被唯一地确定。 开发了具有多个未知数的电磁源的数学模型，并且建立了将模型的未知数与测量值相关联的方程组。 求解方程组以确定电磁源的特性。 本公开还涉及用于执行该方法的装置。