公开(公告)号：US20180105582A1

公开(公告)日：2018-04-19

申请号：US15686675

申请日：2017-08-25

申请人： SULTAN QABOOS UNIVERSITY

发明人： SIDGI SYED ANWER ABDO HASSON ,  ALI A. H. AL-JABRI

IPC分类号： C07K16/10 ,  A23L33/105 ,  A61K35/20 ,  A61K36/285 ,  C07K16/04

CPC分类号： C07K16/1045 ,  A23C9/00 ,  A23C9/20 ,  A23L33/105 ,  A61K35/20 ,  A61K36/28 ,  A61K36/285 ,  A61K2039/53 ,  C07K16/04 ,  C07K2317/12 ,  C07K2317/22 ,  C07K2317/569 ,  C07K2317/76

摘要： A therapeutic composition can include an herbal composition having solid material or liquid extracts from the solid material of at least one of Saussurea acrophila Diels, Saussurea ceratocarpa, and Aucklandia lappa Decne. The solid material may include one or more of parts or the whole of the stem, the bark, the flowers and the roots of one or more, but preferably all of Saussurea acrophila Diels, Saussurea ceratocarpa, and Aucklandia lappa Decne. The therapeutic composition can include camel milk, alone, or in combination with the herbal composition. The camel milk can be HIV-immunized camel milk. The HIV-immunized camel milk can be obtained by immunizing a camel against HIV by administering to the camel the modified DNA plasmids of SEQ. ID No.: 3 and SEQ ID No.: 4 and obtaining the milk from the immunized camel.

公开(公告)号：US20170232063A1

公开(公告)日：2017-08-17

申请号：US15421245

申请日：2017-01-31

申请人： FONTERRA CO-OPERATIVE GROUP LIMITED

发明人： Aaron Calvin Fanning ,  Hasmukh Ambalal Patel ,  Johannes Schalk ,  Ramon Stafford Hall ,  Roger Richard Schwarzenbach ,  Sergey Yevgenievich Ukraintsev

IPC分类号： A61K38/17 ,  A23C9/142 ,  A23L2/66 ,  A23J1/20 ,  A23L33/19 ,  A61K35/20 ,  A23C9/146

CPC分类号： A61K38/1709 ,  A23C9/142 ,  A23C9/1422 ,  A23C9/1427 ,  A23C9/146 ,  A23C9/20 ,  A23J1/20 ,  A23J1/202 ,  A23L2/66 ,  A23L33/19 ,  A23V2002/00 ,  A61K35/20 ,  A61K47/46 ,  A23V2250/54246

摘要： Casein compositions for increasing the rate of gastric emptying following ingestion of the composition, increasing the digestibility of a protein composition, or increasing the rate of delivery of amino acids to the blood, or for increasing the blood serum concentration of free leucine in a subject, preferably to substantially the same level as whey protein, the casein being about 10 to about 100% calcium depleted, having a degree of hydrolysis less than about 1% and having an unmodified phosphorylation pattern.

公开(公告)号：US09226914B2

公开(公告)日：2016-01-05

申请号：US13942827

申请日：2013-07-16

申请人： Mead Johnson Nutrition Company

发明人： Chenzhong Kuang ,  Yan Xiao ,  Eduard Poels ,  Zeina Jouni ,  Dirk Hondmann

IPC分类号： A23L1/29 ,  A23L1/30 ,  A23C9/13 ,  A61K9/00 ,  A61K31/202 ,  A61K35/00 ,  A61K31/385 ,  A61K31/7012 ,  A61K38/40 ,  A23C9/20 ,  A23L1/305

CPC分类号： A61K31/385 ,  A23C9/20 ,  A23L33/12 ,  A23L33/19 ,  A23L33/40 ,  A23V2002/00 ,  A61K31/202 ,  A61K31/7012 ,  A61K35/00 ,  A61K35/741 ,  A61K38/011 ,  A61K38/018 ,  A61K38/40 ,  A23V2200/322 ,  A23V2250/026 ,  A23V2250/1868 ,  A61K2300/00

摘要： Disclosed are methods for promoting neuronal health and/or development in a subject by providing nutritional compositions comprising docosahexaenoic acid and alpha-lipoic acid. The nutritional composition may further include lactoferrin, a prebiotic, a probiotic, and mixtures thereof. Additionally disclosed are methods for accelerating the development of neuronal activity and/or strengthening electrochemical synapse signaling by providing the nutritional composition(s) disclosed herein to a target subject.

摘要翻译： 公开了通过提供包含二十二碳六烯酸和α-硫辛酸的营养组合来促进受试者的神经元健康和/或发育的方法。 营养组合物还可以包括乳铁蛋白，益生元，益生菌及其混合物。 另外公开的是通过向目标受试者提供本文公开的营养组合物来加速神经元活性的发展和/或加强电化学突触信号的方法。

公开(公告)号：US20150087678A1

公开(公告)日：2015-03-26

申请号：US14394916

申请日：2013-04-12

申请人： Nogra Pharma Limited

发明人： Sergio Baroni ,  Salvatore Bellinvia ,  Francesca Viti

IPC分类号： A61K31/196 ,  A23C19/09 ,  A23C13/12 ,  A23C21/08 ,  A61K31/4439 ,  A23C9/20

CPC分类号： A61K31/196 ,  A23C9/152 ,  A23C9/20 ,  A23C13/12 ,  A23C19/09 ,  A23C21/08 ,  A61K31/195 ,  A61K31/4439 ,  A61K31/606 ,  A61K31/635

摘要： Disclosed herein are methods for treating lactose intolerance, including compounds that may be specific or modulate PPARγ receptors.

摘要翻译： 本文公开了治疗乳糖不耐症的方法，包括可能是特异性或调节PPARγ受体的化合物。

公开(公告)号：US20150023923A1

公开(公告)日：2015-01-22

申请号：US13942827

申请日：2013-07-16

申请人： Mead Johnson Nutrition Company

发明人： Chenzhong Kuang ,  Yan Xiao ,  Eduard Poels ,  Zeina Jouni ,  Dirk Hondmann

IPC分类号： A61K31/385 ,  A61K31/7012 ,  A23L1/30 ,  A61K35/00 ,  A23L1/29 ,  A61K31/202 ,  A61K38/40

CPC分类号： A61K31/385 ,  A23C9/20 ,  A23L33/12 ,  A23L33/19 ,  A23L33/40 ,  A23V2002/00 ,  A61K31/202 ,  A61K31/7012 ,  A61K35/00 ,  A61K35/741 ,  A61K38/011 ,  A61K38/018 ,  A61K38/40 ,  A23V2200/322 ,  A23V2250/026 ,  A23V2250/1868 ,  A61K2300/00

摘要： The present disclosure relates to methods for promoting neuronal health and/or development in a subject by providing nutritional compositions comprising docosahexaenoic acid and alpha-lipoic acid. The nutritional composition may further include lactoferrin, a prebiotic, a probiotic, and mixtures thereof. Additionally the present disclosure provides methods for accelerating the development of neuronal activity and/or strengthening electrochemical synapse signaling by providing the nutritional composition(s) disclosed herein to a target subject.

摘要翻译： 本公开涉及通过提供包含二十二碳六烯酸和α-硫辛酸的营养组合来促进受试者的神经元健康和/或发育的方法。 营养组合物还可以包括乳铁蛋白，益生元，益生菌及其混合物。 另外，本公开提供了通过向目标受试者提供本文公开的营养组合物来加速神经元活性和/或加强电化学突触信号传导的方法。

公开(公告)号：US08842263B1

公开(公告)日：2014-09-23

申请号：US06514036

申请日：1983-07-11

申请人： William James Montgomery

发明人： William James Montgomery

IPC分类号： G01P3/36

CPC分类号： G01S17/66 ,  A23C9/158 ,  A23C9/20 ,  A23C11/04 ,  F41G7/26 ,  G01S3/788 ,  G01S7/4812 ,  G01S7/4813 ,  G01S7/4817

摘要： To determine two positional co-ordinates, of a point (D) within a space, a beam (10) a radiation is caused to illuminate a part of the space and is deflected cylindrically over the space, the beam being modulated in phase with the cyclical movement such that the radiation incident upon the point (D) includes enough information to identify the point. Embodiments with rotational (r, θ) and Cartesian (x, y) co-ordinate axes are disclosed.

摘要翻译： 为了确定空间内的点（D）的两个位置坐标，光束（10）被引起照射一部分空间并且在空间上圆柱形偏转，光束与 使得入射在点（D）上的辐射包括足够的信息来识别该点。 公开了具有旋转（r，＆amp; t）和笛卡尔坐标（x，y）坐标轴的实施例。

公开(公告)号：US20140141125A1

公开(公告)日：2014-05-22

申请号：US13820782

申请日：2012-07-12

申请人： Gye-Hwan Roh

发明人： Gye-Hwan Roh

IPC分类号： A23C9/20

CPC分类号： A23C9/20 ,  A23C9/1315 ,  A23C9/1322 ,  A23C9/137 ,  A23C9/152 ,  A23C9/1522 ,  A23C9/1528 ,  A23C9/1544 ,  A23C9/158 ,  A23C15/12 ,  A23C19/0921 ,  A23L29/256 ,  A23P10/30 ,  A23V2002/00 ,  A23V2200/224 ,  A23V2250/1592 ,  A23V2250/1882 ,  A23V2250/5026 ,  A23V2250/5116 ,  A23V2250/708 ,  A23V2250/712

摘要： Provided are a dairy product containing functional alginic acid beads and a preparation method thereof. The dairy product includes a composition containing 1 to 10% of alginic acid beads based on the weight of the dairy product. The alginic acid beads are formed by dropping into a 1.0 to 5.0% calcium lactate solution, a mixed solution including 0.5 to 15.0% by weight of a functional material including vitamin C, vitamin E, iron, omega-3, a water-soluble dietary fiber or a combination thereof, 25.0 to 45.0% by weight of refined sugar, 0.5 to 2.0% by weight of sodium alginate, 0.001 to 0.1% by weight of a grapefruit seed extract, 0.5 to 1.5% by weight of a natural pigment and 37.0 to 60.0% by weight of purified water. The dairy product contains alginic acid beads containing functional dietary fiber material and functional material in beads visible to the naked eyes to provide nutritional satisfaction and visual satisfaction. The product provides children and the old intaking thereof and young people favoring trendy beverages with balanced nutrients. Particularly, the present invention contributes to the prevention of childhood obesity, promotes consumption of the dairy products to enhance national health and profitability for livestock farms, and maximizes functionality and nutritional properties of the dairy products by fundamentally solving deficiency of the dietary fiber content.

摘要翻译： 提供含有功能性海藻酸珠粒的乳制品及其制备方法。 乳制品包含基于乳制品重量的含有1-10％海藻酸珠粒的组合物。 藻酸珠是通过滴入1.0-5.0％的乳酸钙溶液中形成的，该溶液包括0.5至15.0重量％的功能材料，包括维生素C，维生素E，铁，ω-3，水溶性膳食 纤维或其组合，25.0至45.0重量％的精制糖，0.5至2.0重量％的藻酸钠，0.001至0.1重量％的葡萄柚籽提取物，0.5至1.5重量％的天然颜料和37.0 至60.0重量％的纯化水。 乳制品含有海藻酸珠，含有功能性膳食纤维材料和肉眼可见的珠粒中的功能材料，以提供营养满意度和视觉满意度。 该产品提供儿童，老年人和年轻人喜欢时尚饮料均衡营养。 特别地，本发明有助于预防儿童肥胖，促进乳制品的消费，以增强家畜养殖场的国家健康和利润，并通过从根本上解决膳食纤维含量的不足，最大化乳制品的功能和营养特性。

公开(公告)号：US20140010764A1

公开(公告)日：2014-01-09

申请号：US14014089

申请日：2013-08-29

申请人： SOMNACEUTICS LIMITED

发明人： Robert Bartlett Elliott

IPC分类号： A61K35/20 ,  A23C9/20

CPC分类号： A61K35/20 ,  A23C9/20 ,  A23K20/147 ,  A23L33/18 ,  A23L33/19 ,  A23V2002/00 ,  A61K38/018 ,  A23V2200/322 ,  A23V2250/54246

摘要： Milk-based products and drinks are provided including specified forms of identified proteins or fragments thereof, as are methods for the use of such milk-based products and drinks in the promotion of sleep.

摘要翻译： 提供基于乳的产品和饮料，包括确定的蛋白质或其片段的特定形式，以及在促进睡眠中使用这种基于乳的产品和饮料的方法。

公开(公告)号：US20130273046A1

公开(公告)日：2013-10-17

申请号：US13791055

申请日：2013-03-08

申请人： EDIMER PHARMACEUTICALS, INC. ,  UNIVERSITE DE LAUSANNE

发明人： Pascal Schneider ,  Nathalie Dunkel ,  Stéphane Demotz

IPC分类号： A61K39/395 ,  A23C9/20

CPC分类号： C07K16/2863 ,  A23C9/20 ,  A23C9/206 ,  A23C2230/10 ,  A61K39/39541 ,  A61K39/3955 ,  A61K2039/505 ,  C07K16/2878 ,  C07K2317/33 ,  C07K2317/55 ,  C07K2317/565 ,  C07K2317/73 ,  C07K2317/732 ,  C07K2317/75 ,  C07K2317/92 ,  C07K2317/94

摘要： The present invention concerns the preparation of substantially purified agonist anti-EDAR monoclonal antibodies or isolated monoclonal antibody fragments or antigen binding portions or fragments thereof. The invention further relates to isolated agonist anti-EDAR monoclonal antibodies or isolated monoclonal antibody fragments or antigen binding portions or fragments thereof as well as their use in the treatment of X-linked hypohidrotic ectodermal dysplasia and tooth agenesis. The invention also relates to a pharmaceutical composition comprising said isolated agonist anti-EDAR monoclonal antibodies or isolated monoclonal antibody fragments or antigen binding portions or fragments thereof and to a method of treating X-linked hypohidrotic ectodermal dysplasia and tooth agenesis. Finally, the present invention concerns a pharmaceutical kit comprising said isolated agonist anti-EDAR monoclonal antibodies or isolated monoclonal antibody fragments or antigen binding portions or fragments thereof.

摘要翻译： 本发明涉及基本纯化的激动剂抗EDAR单克隆抗体或分离的单克隆抗体片段或抗原结合部分或其片段的制备。 本发明还涉及分离的激动剂抗EDAR单克隆抗体或分离的单克隆抗体片段或抗原结合部分或其片段，以及它们在治疗X连锁的hypohidrotic外胚层发育不良和牙齿发育不良中的用途。 本发明还涉及包含所述分离的激动剂抗EDAR单克隆抗体或分离的单克隆抗体片段或抗原结合部分或其片段的药物组合物，以及治疗X连锁的hypohidrotic外胚层发育不良和牙齿发育不全的方法。 最后，本发明涉及包含所述分离的激动剂抗EDAR单克隆抗体或分离的单克隆抗体片段或抗原结合部分或其片段的药物试剂盒。

公开(公告)号：US20120171231A1

公开(公告)日：2012-07-05

申请号：US12980819

申请日：2010-12-29

申请人： Anja Wittke ,  Cecilia Munoz ,  Dattatreya Banavara

发明人： Anja Wittke ,  Cecilia Munoz ,  Dattatreya Banavara

IPC分类号： A61K39/00 ,  A61P37/04

CPC分类号： A61K38/40 ,  A23C9/20 ,  A23L33/135 ,  A23L33/19 ,  A23L33/40 ,  A61K35/741

摘要： The present disclosure relates to the use of nutritional compositions including lactoferrin produced by a non-human source in stimulating innate immune cells, such as macrophages, neutrophils, and dendritic cells.

摘要翻译： 本公开内容涉及包含非人源产生的乳铁蛋白的营养组合物在刺激先天免疫细胞如巨噬细胞，嗜中性粒细胞和树突细胞中的用途。