公开(公告)号：US20240138401A1

公开(公告)日：2024-05-02

申请号：US18548910

申请日：2022-03-02

申请人： MAX-PLANCK-GESELLSCHAFT ZUR FÖRDERUNG DER WISSENSCHAFTEN E. V.

发明人： Stefan RAUNSER ,  Sebastian TACKE ,  Joachim BESLER

IPC分类号： A01N1/02 ,  G01N1/42

CPC分类号： A01N1/0284 ,  A01N1/0257 ,  A01N1/0268 ,  G01N1/42

摘要： The present invention relates to a storage device (1) for storing cryogenic samples (2), comprising at least one sample holder (3), the sample holder being configured to hold at least one cryogenic sample (2). According to the present invention, the storage device (1) further comprises an elongated sample transport unit (4) configured to releasably hold the at least one sample holder (3) and to be inserted into an internal space (50) of a cryogenic storage dewar (5) through an opening (51) of the cryogenic storage dewar to completely submerge the sample transport unit into a cryogenic liquid (6) residing in the internal space, wherein the sample transport unit is further configured to move said at least one sample holder along a predefined path from a storage position into a removal position, from which the at least one sample holder can be removed from the internal space of the cryogenic storage dewar. The sample transport unit may comprise a chain (40) to be circulated to move the sample holder along said pre-defined path, the chain being looped around a first and a second toothed wheel (41,42).

公开(公告)号：US20230276791A1

公开(公告)日：2023-09-07

申请号：US18196720

申请日：2023-05-12

申请人： CORNING INCORPORATED

发明人： William Joseph Lacey ,  Gregory Roger Martin ,  Allison Jean Tanner

IPC分类号： A01N1/02 ,  B01L3/00 ,  C12M1/00

CPC分类号： A01N1/0268 ,  B01L3/50825 ,  C12M45/22 ,  B01L3/5082 ,  B01L2300/042 ,  B01L2300/046 ,  B01L2300/0858 ,  B01L2300/0609 ,  B01L2300/123 ,  B01L2200/141 ,  B01L2300/043 ,  B01L2300/0832

摘要： Vial assemblies comprise a tubular body and a cap, the cap including a first portion configured to abut a lip of an open end of the tubular body, a threaded portion configured to couple to threading on an internal surface of the tubular body, and a second portion protruding from the threaded portion and extending into a cavity of the tubular body. Methods for storing and removing frozen samples from such vial assemblies are also described.

公开(公告)号：US20230191415A1

公开(公告)日：2023-06-22

申请号：US18113297

申请日：2023-02-23

申请人： TMRW Life Sciences, Inc.

发明人： William Alan Blair ,  Timothy Alan Sharp ,  Amit Gupta ,  Kathryn Josephine Go ,  William Nicholas Garbarini, JR.

IPC分类号： B01L3/00 ,  A01N1/02 ,  B01L7/00

CPC分类号： B01L3/50851 ,  A01N1/0268 ,  B01L3/5029 ,  B01L7/50 ,  B01L3/50825 ,  B01L2300/1883 ,  B01L2200/147 ,  B01L2300/042

摘要： A system and method facilitates transfers of specimen containers (e.g., vials with caps) between storage cassettes and carrier cassettes. The storage cassettes are designed to be stored in cryogenic refrigerators while the carrier cassettes are designed to be temporarily stored in a portable carrier. Identification information is read from wireless transponders carried by the specimen containers. Visual mappings of the positions of the specimen container in the cassettes is provided. Presence and position of the specimen containers in the cassettes is verified, and alerts of inconsistencies provided along with corrective commands. Inventories of specimen container and even specific specimen holders are provided.

公开(公告)号：US20230189795A1

公开(公告)日：2023-06-22

申请号：US18107930

申请日：2023-02-09

申请人： The Regents of the University of California

发明人： Boris Rubinsky ,  Gabriel Nastase ,  Gideon Ukpai

IPC分类号： A01N1/02

CPC分类号： A01N1/0284 ,  A01N1/0257 ,  A01N1/0221 ,  A01N1/0268 ,  A01N1/0289 ,  B01L2300/1894

摘要： The disclosure provides processes for temperature and pressure controlled cryopreservation of samples by using isochoric systems.

公开(公告)号：US11672249B2

公开(公告)日：2023-06-13

申请号：US17296987

申请日：2019-01-08

申请人： SHANGHAI ORIGINCELL BIOLOGICAL CRYO EQUIPMENT CO., LTD.

发明人： Jianguo Qu ,  Lingling Liu ,  Huoming Qiao ,  Jianxin Wang

IPC分类号： A01N1/02 ,  B65D81/22 ,  B65D81/38 ,  B65D90/00

CPC分类号： A01N1/0268 ,  B65D81/22 ,  B65D81/3806 ,  B65D81/3811 ,  B65D90/0073

摘要： A liquid nitrogen tank includes a tank, a storage rack and a drive component. The tank includes a tank cover, a tank body, a vacuum cavity layer and a heat-insulating cavity layer. The tank cover is disposed to cover on the tank body. An access door is provided on the tank body. A storage cavity is provided in the tank body. The heat-insulating cavity layer is provided on a periphery of the storage cavity. The vacuum cavity layer is provided on a periphery of the heat-insulating cavity layer. The storage rack is provided in the storage cavity. A plurality of cryopreservation tube racks are stored in the storage rack. The drive component can drive the storage rack to rotate and move up and down in the storage cavity, and can drive the plurality of cryopreservation tube racks to move to a position corresponding to the access door.

公开(公告)号：US20230177303A1

公开(公告)日：2023-06-08

申请号：US18060778

申请日：2022-12-01

申请人： Gourgen AMBARTSOUMIAN

发明人： Gourgen AMBARTSOUMIAN

IPC分类号： G06K19/077 ,  B65C3/02 ,  B65C9/46 ,  B32B7/12 ,  A01N1/02

CPC分类号： G06K19/0776 ,  B65C3/02 ,  B65C9/46 ,  B32B7/12 ,  A01N1/0268 ,  B32B2519/00 ,  B32B2307/412 ,  B32B2307/75 ,  B32B2307/732

摘要： A label for a tube having a diameter D may have a transparent facestock. A printing area is defined on a first surface of the transparent facestock, the printing area configured to receive data thereon, the printing area covering only a portion of the transparent facestock, whereby a shielding portion of the length of the label is transparent. An adhesive layer is on a second surface of the facestock. A wireless communication inlay is adhered to the adhesive layer in a portion of the label corresponding to the printing area. The printing area and the facestock are sized for the shielding portion to overlap at least partially the printing area when the label is wrapped on a tube.

公开(公告)号：US20180242573A1

公开(公告)日：2018-08-30

申请号：US15774883

申请日：2016-11-03

申请人： Corning Incorporated

发明人： William Joseph Lacey ,  Gregory Roger Martin ,  Allison Jean Tanner

IPC分类号： A01N1/02 ,  B01L3/00

CPC分类号： A01N1/0268 ,  B01L3/5082 ,  B01L3/50825 ,  B01L2200/141 ,  B01L2300/042 ,  B01L2300/043 ,  B01L2300/046 ,  B01L2300/0609 ,  B01L2300/0832 ,  B01L2300/0858 ,  B01L2300/123 ,  C12M45/22

摘要： Vial assemblies comprise a tubular body and a cap, the cap including a first portion configured to abut a lip of an open end of the tubular body, a threaded portion configured to couple to threading on an internal surface of the tubular body, and a second portion protruding from the threaded portion and extending into a cavity of the tubular body. Methods for storing and removing frozen samples from such vial assemblies are also described.

公开(公告)号：US10001313B2

公开(公告)日：2018-06-19

申请号：US14021142

申请日：2013-09-09

申请人： Stan C. Petrov

发明人： Stan C. Petrov

IPC分类号： F25J3/00 ,  B65B63/08 ,  F25D23/12 ,  F25D3/02 ,  F17C1/00 ,  F17C3/00 ,  F17C13/00 ,  F25D3/10 ,  F25D29/00 ,  A01N1/02 ,  F17C13/02

CPC分类号： F25D3/107 ,  A01N1/0257 ,  A01N1/0268 ,  A01N1/0273 ,  F17C13/025 ,  F17C2205/0338 ,  F17C2205/0391 ,  F25D29/001

摘要： A compact, mobile communicating carrying case for the transport and storage of temperature-sensitive materials. The carrying case regulates to temperature presets that can be altered real time directly or remotely. Cryogenic temperature control is provided by use of a low boiling point liquid coolant, like liquid nitrogen or air that accelerates in a multicore cooling system. A microprocessor-controlled double function solenoid acting as a valve and sensor, temperature sensors, and several mechanical one way release valves regulate the cooling system. Peripheral integrated modules collect, send, receive and display information on the case and on smart devices about location, core temperature, the carrier and the nature of the enclosed material. The carrying case provides a compact laser-etched sterile working area, in addition to a set of basic instruments, needed for procedures using the biological materials.

公开(公告)号：US20180094232A1

公开(公告)日：2018-04-05

申请号：US15782534

申请日：2017-10-12

申请人： The General Hospital Corporation

发明人： Mehmet Toner ,  Heidi Y. Elmoazzen ,  Thomas L. Toth ,  Yunseok Heo ,  Ho-Joon Lee ,  Nilay Chakraborty

IPC分类号： C12N1/04 ,  A01N1/02 ,  G01N1/42

CPC分类号： C12N1/04 ,  A01N1/0268 ,  A01N1/0284 ,  G01N1/42

摘要： Manufactured capillary tubes can include: a tubular member; and a coating applied partially covering the tubular member, the coating defining a window where the tubular member is free of the coating. Kits containing and methods related to the capillary tubes can be used for the cryopreservation of cells.

公开(公告)号：US20180042220A1

公开(公告)日：2018-02-15

申请号：US15784460

申请日：2017-10-16

申请人： TERUMO KABUSHIKI KAISHA ,  Osaka University

发明人： Shigeru MIYAGAWA ,  Yoshiki Sawa ,  Hirotatsu Ohkawara ,  Satsuki Fukushima ,  Atsuhiro Saito ,  Hiroko Iseoka

IPC分类号： A01N1/02

CPC分类号： A01N1/0268 ,  A01N1/021 ,  C12N1/04

摘要： Methods are disclosed of freezing, cryopreserving, and transferring a frozen sheet-shaped cell culture. The method of freezing includes (1) a step of immersing in a cryopreservation solution a sheet-shaped cell culture supported by a mesh-shaped support body; (2) a step of removing the cryopreservation solution adhered to the sheet-shaped cell culture, while keeping the sheet-shaped cell culture supported by the mesh-shaped support body; (3) a step of enclosing the sheet-shaped cell culture in a cold-resistant film, an upper surface and a lower surface of the sheet-shaped cell culture being covered by the mesh-shaped support body; and (4) a step of freezing the sheet-shaped cell culture.