公开(公告)号：US06963451B2

公开(公告)日：2005-11-08

申请号：US10474806

申请日：2002-06-21

申请人： Koichi Se ,  Yutaka Omura

发明人： Koichi Se ,  Yutaka Omura

IPC分类号： G02B5/02 ,  F21V7/04

CPC分类号： G02B5/0221 ,  G02B5/0268 ,  G02B5/0278

摘要： The invention provides a sheet (1) comprising a light-transmittable resin, in which irregularities are formed on both sides (1a) and (1b) of the sheet, the average surface roughness of one side (1a) which becomes the light-entering side is from 0.2 to 5.0 μm and larger than the average surface roughness of the opposite side (1b) that becomes the light-departing side, wherein the average surface roughness of the opposite side (1b) is from 0.2 to 2.0 μm, and the surface area ratio of the one side (1a) is smaller than the surface area ratio of the opposite side (1b).

摘要翻译： 本发明提供了一种片材（1），其包括可透光树脂，其中在片材的两侧（1a）和（1b）上形成凹凸，其中一侧（1a）的平均表面粗糙度成为 光进入侧为0.2〜5.0μm，大于成为脱光侧的相反侧（1b）的平均表面粗糙度，其中相对侧（1b）的平均表面粗糙度为0.2〜 2.0μm，一侧（1a）的表面积比小于相对面（1b）的表面积比。

公开(公告)号：US4997656A

公开(公告)日：1991-03-05

申请号：US356618

申请日：1989-05-23

申请人： Yasuo Shikinami ,  Seiei Sasatani

发明人： Yasuo Shikinami ,  Seiei Sasatani

IPC分类号： A61K9/70 ,  A61L15/44 ,  A61L15/58 ,  C08G18/10 ,  C08G18/71 ,  C09J175/08

CPC分类号： A61K9/7084 ,  A61L15/58 ,  C08G18/10 ,  C08G18/71 ,  C09J175/08

摘要： An adhesive for percutaneous administration having a drug-containing layer composed of a base component mainly comprising a heat-sensitive and water-sensitive amphiphilic polymer and a drug incorporated in the base component. The amphiphilic compound has a characteristic hydrophobicity-hydrophilicity tapered structure, and a variety of liquid or solid or lipophilic (hydrophobic) or hydrophilic drugs of a broad range can stably be dissolved or dispersed therein. The drug in the drug-containing layer remains stable without being released or diffused while the adhesives are stored, and upon application to the skin, the drug is gradually released and diffused into the skin with high availability in a specifically controlled pattern. The present adhesive is especially advantageous for endermic presentation of a slight amount of a substance of high physiological activity which is unstable and is easily decomposed by heat or water.

摘要翻译： 一种用于经皮给药的粘合剂，其具有由主要包含热敏性和水敏性两亲性聚合物的基础组分和掺入基础组分中的药物组成的药物含有层。 两亲性化合物具有特征性的疏水性 - 亲水性锥形结构，并且可以稳定地溶解或分散各种范围广泛的液体或固体或亲脂性（疏水性）或亲水性药物。 含药层中的药物在粘合剂储存时保持稳定而不被释放或扩散，并且在施用于皮肤时，药物以特定控制的模式以高可用性逐渐释放并扩散到皮肤中。 本发明的粘合剂对于微量的高生理活性物质的外来物质呈现是不利的，并且易于被热或水分解。

公开(公告)号：US4724111A

公开(公告)日：1988-02-09

申请号：US941487

申请日：1986-12-15

申请人： Masanori Iwata ,  Yoshiaki Tatsumi

发明人： Masanori Iwata ,  Yoshiaki Tatsumi

IPC分类号： F16L33/00 ,  B29C20060101 ,  B29C45/14 ,  B29C57/00 ,  B29L23/18 ,  F16L25/00 ,  F16L33/28 ,  B28B1/48

CPC分类号： F16L25/0036 ,  B29C45/14598 ,  Y10S285/903 ,  Y10S425/218

摘要： A method of molding a sleeve on a corrugated pipe consisting of an inner wall and fusion-bond ridges. Two clamps can close to engage several of the ridges. One to three of the ridges project into a molding space between the clamps. A core is inserted into pipe and closes the molding space. Hot pressurized resin softens and collapses the projected ridges and fusion bonds the pipe to the sleeve portion of the molding space.

摘要翻译： 在由内壁和熔接脊组成的波纹管上成型套筒的方法。 两个夹子可以接近几个脊。 一到三个脊突出到夹子之间的成型空间中。 将芯插入管中并封闭成型空间。 热加压树脂软化和塌缩突出的脊，并将管道熔合到模制空间的套筒部分。

公开(公告)号：US20160058549A1

公开(公告)日：2016-03-03

申请号：US14837627

申请日：2015-08-27

申请人： TAKIRON CO., LTD.

发明人： Minoru NODA ,  Hiroshi MORII

IPC分类号： A61F2/08

CPC分类号： A61F2/0811 ,  A61B2017/0403 ,  A61B2017/0412 ,  A61F2/0805 ,  A61F2002/0829 ,  A61F2002/0852 ,  A61F2002/087 ,  A61F2002/0882 ,  A61F2210/0004 ,  A61F2250/0089

摘要： A ligament fixture to be inserted and fixed into a fitting hole formed in an in-vivo bone is provided, and includes an in-vivo degradable and absorbable material which is a polymer-bioceramic composite material. The ligament fixture has at least one pair of opposed surfaces which are inclined faces gradually getting closer to each other toward to a front-end side of the ligament fixture and which form a wedge shape having a resistance imparting parts on each of the inclined faces. The ligament fixture includes a front-end part having a cross-sectional profile smaller than a cross-sectional profile of the fitting hole, and a main body part continuing from the front-end part, the main body part including a section having a cross-sectional profile larger than the cross-sectional profile of the fitting hole.

摘要翻译： 提供插入并固定在体内骨形成的嵌合孔中的韧带夹具，并且包括作为聚合物 - 生物陶瓷复合材料的体内可降解和可吸收的材料。 所述韧带夹具具有至少一对相对的表面，所述至少一对相对表面是倾斜面逐渐变得彼此靠近所述韧带夹具的前端侧并且形成在每个倾斜面上具有阻力赋予部分的楔形。 所述韧带固定装置包括具有小于所述嵌合孔的截面形状的截面形状的前端部，以及与所述前端部连续的主体部，所述主体部包括具有十字形的部分 - 截面轮廓大于装配孔的横截面轮廓。

公开(公告)号：US20100331986A1

公开(公告)日：2010-12-30

申请号：US12810237

申请日：2008-12-25

申请人： Yasuo Shikinami

发明人： Yasuo Shikinami

IPC分类号： A61F2/44 ,  A61F2/02

CPC分类号： A61L27/58 ,  A61F2/30756 ,  A61F2/30771 ,  A61F2/3094 ,  A61F2/442 ,  A61F2002/30009 ,  A61F2002/30016 ,  A61F2002/30062 ,  A61F2002/30064 ,  A61F2002/30131 ,  A61F2002/30492 ,  A61F2002/30784 ,  A61F2002/30841 ,  A61F2002/30971 ,  A61F2002/448 ,  A61F2002/4495 ,  A61F2210/0004 ,  A61F2220/0025 ,  A61F2230/0013 ,  A61F2250/0019 ,  A61F2250/0028 ,  A61F2310/00179 ,  A61F2310/00592 ,  A61L27/34 ,  A61L27/427 ,  A61L27/50 ,  A61L2430/06

摘要： A biomaterial for an artificial cartilage is disclosed. The biomaterial eliminates the risk of possible adverse effects due to scattering of fragments of the biodegradable and bioabsorbable polymers and shows enhanced adhesiveness which allows more solid adhesion of the artificial cartilage to vertebral bodies and the like. The biomaterial includes an organized structure comprising organic fibers arranged in one of a multiaxial three-dimensional woven or knitted structure having three or more axes and a combined structure of the woven structure and the knitted structure; and a biodegradable and bioabsorbable pin provided inside the organized structure.

摘要翻译： 公开了人造软骨的生物材料。 生物材料消除了由于可生物降解的和生物可吸收的聚合物的片段的散射引起的可能的不利影响的风险，并且显示增强的粘附性，其允许人造软骨更牢固地粘附到椎体等。 所述生物材料包括有机纤维，所述有机纤维被布置在具有三个或更多个轴的多轴三维机织或针织结构中的一个中，并且所述机织结构和针织结构的组合结构; 以及设置在组织结构内的可生物降解和生物可吸收的销。

公开(公告)号：US20100131074A1

公开(公告)日：2010-05-27

申请号：US12066688

申请日：2006-09-13

申请人： Yasuo Shikinami

发明人： Yasuo Shikinami

IPC分类号： A61F2/28

CPC分类号： A61L27/56 ,  A61L27/446 ,  A61L27/58

摘要： A composite porous object which comprises a biodegradable and bioabsorbable polymer containing bioactive bioceramic particles dispersed therein, the composite porous object having in inner parts thereof large voids 1 having a void diameter of 40-600 μm and small voids 2 having a void diameter of 1 μm or smaller, at least part of the large voids 1 and at least part of the small voids 2 constituting interconnected voids. The small voids 2 are formed in the biodegradable and bioabsorbable polymer walls 3 which surround the large voids 1 and in the surface of the walls 3. It is preferred that 40% or more of all voids constitute interconnected voids.The walls 3 surrounding the large voids 1 in the composite porous object are progressively replaced by bone tissues conducting from the surface of the walls (internal surface of the large voids 1) to inner parts of the walls and by bone tissues conducting from the internal surface of the small voids 2 in the walls 3 toward surrounding parts. The degree of replacement by bone tissues is hence high, and the composite porous object is almost wholly replaced by bone tissues in the living body in a relatively short time period.

摘要翻译： 一种复合多孔物体，其包含分散在其中的生物活性生物陶瓷颗粒的生物可降解和生物可吸收聚合物，所述复合多孔物体在其内部具有空隙直径为40-600μm的大空隙1和空隙直径为1μm的小空隙2 或更小，至少部分大空隙1和构成互连空隙的小空隙2的至少一部分。 小空隙2形成在围绕大空隙1和壁3表面的生物可​​降解和生物可吸收的聚合物壁3中。优选所有空隙的40％或更多构成互连的空隙。 围绕复合多孔物体中的大空隙1的壁3逐渐地由从壁的表面（大空隙1的内表面）传导到壁的内部部分和从内表面传导的骨组织的骨组织 的壁3中的小空隙2朝向周围部分。 因此，骨组织的置换程度较高，复合多孔物质在相当短的时间内几乎完全被生物体中的骨组织代替。

公开(公告)号：US07494713B2

公开(公告)日：2009-02-24

申请号：US11661192

申请日：2005-03-03

申请人： Xuefang Song ,  Satoru Matsumoto ,  Tadanori Watanabe

发明人： Xuefang Song ,  Satoru Matsumoto ,  Tadanori Watanabe

IPC分类号： B32B9/04 ,  B32B27/00

CPC分类号： B32B27/08 ,  B32B27/12 ,  B32B27/18 ,  B32B27/20 ,  B32B27/32 ,  B32B27/327 ,  B32B2471/00 ,  D06N3/045 ,  D06N3/183 ,  D06N3/186 ,  E04F15/10 ,  Y10T428/31504 ,  Y10T428/31573 ,  Y10T428/31576 ,  Y10T428/31587 ,  Y10T428/31855

摘要： An object is to provide a flooring material which, when applied, is satisfactory in applicability and conformability to the substrate and which combines all of various properties required of flooring materials, such as nonfouling properties, marring resistance, and flexibility. The flooring material comprises synthetic resin A, which comprises a polyethylene resin and/or an ethylene/α-olefin copolymer resin, synthetic resin B, which comprises a flexible ethylene-based resin, and synthetic resin C, which comprises a thermoplastic elastomer, and has: a face layer formed from a synthetic resin composition obtained by compounding ingredients comprising 30-60 parts by weight of synthetic resin A, 10-50 parts by weight of synthetic resin B, 10-40 parts by weight of synthetic resin C, the sum of the resins A, B, and C being 100 parts by weight, 1-15 parts by weight of a viscosity improver, and 150-500 parts by weight of a filler; and a groundwork layer formed from a synthetic resin composition obtained by compounding ingredients comprising 0-30 parts by weight of synthetic resin A, 30-60 parts by weight of synthetic resin B, 41-60 parts by weight of synthetic resin C, the sum of the resins A, B, and C being 100 parts by weight, 1-15 parts by weight of a viscosity improver, and 150-500 parts by weight of a filler.

摘要翻译： 本发明的目的是提供一种地板材料，其在施加时具有令人满意的适用性和与基材的一致性，并且其结合了地板材料所需的各种性能，例如非结垢性，防结锈性和柔性。 地板材料包括合成树脂A，其包括聚乙烯树脂和/或乙烯/α-烯烃共聚物树脂，包含柔性乙烯基树脂的合成树脂B和包含热塑性弹性体的合成树脂C和 具有：由合成树脂组合物形成的面层，所述合成树脂组合物通过将包含30-60重量份合成树脂A，10-50重量份合成树脂B，10-40重量份合成树脂C， 树脂A，B和C的总和为100重量份，1-15重量份粘度改进剂和150-500重量份填料; 以及由合成树脂组合物形成的基底层，所述合成树脂组合物通过将包含0-30重量份合成树脂A，30-60重量份合成树脂B，41-60重量份合成树脂C， 的树脂A，B和C为100重量份，1-15重量份粘度改进剂和150-500重量份填料。

公开(公告)号：US20020041955A1

公开(公告)日：2002-04-11

申请号：US09964693

申请日：2001-09-28

申请人： TAKIRON CO., LTD.

发明人： Kenji Watanabe ,  Kazuhiro Oritani ,  Osamu Kouzui ,  Takahiro Yokoyama

IPC分类号： B32B027/30

CPC分类号： C08K5/0075 ,  B32B27/20 ,  B32B27/30 ,  C08L23/286 ,  C08L27/06 ,  Y10T428/24942 ,  Y10T428/249945 ,  Y10T428/263 ,  Y10T428/3192 ,  Y10T428/31928 ,  C08L2666/04

摘要： Vinyl chloride resin moldings having excellent fire-retardant property, which have good antistatic property and can prevent adhesion of dust. The molding has an antistatic layer containing a conductive material laminated on at least one side of a base layer comprising a vinyl chloride resin, wherein the base layer has a titanium compound; the base layer has a molybdenum compound; the base layer has a vinyl chloride resin having a specific chlorination degree; the base layer has a phosphorus fire-retarding agent and/or a chlorinated polyethylene; etc.

摘要翻译： 具有优异的阻燃性的氯乙烯树脂成型体，具有良好的抗静电性，并且可以防止灰尘附着。 该成型体具有含有导电性材料的抗静电层，该导电性材料层压在包含氯乙烯树脂的基底层的至少一侧上，其中该基底层具有钛化合物; 基层具有钼化合物; 基层具有特定氯化度的氯乙烯树脂; 基层具有磷阻燃剂和/或氯化聚乙烯; 等等

公开(公告)号：US5773490A

公开(公告)日：1998-06-30

申请号：US605584

申请日：1996-02-22

申请人： Yasuo Shikinami ,  Kunihiro Hata

发明人： Yasuo Shikinami ,  Kunihiro Hata

IPC分类号： C08G18/48 ,  C09J4/00 ,  C08J3/00 ,  C08K3/20 ,  C08L75/00

CPC分类号： C08G18/4837 ,  C08G18/4841 ,  C08G2170/40

摘要： Pressure sensitive adhesives for transdermal absorption formulations comprising a segmented polyurethane, which can control dissolution and a releasing property of drugs of various kinds which are solid at normal temperature; said segment being an alkylene oxide chain which is in a liquid state at a temperature of around normal temperature to around body temperature, and said segment containing a hydrophilic alkylene oxide chain and a hydrophobic alkylene oxide chain, or comprising one or both of them and an alkylene oxide chain in which a hydrophilic moiety and a hydrophobic moiety are present in the mixed manner.

摘要翻译： 用于经皮吸收制剂的压敏粘合剂，其包含分段聚氨酯，其可以控制在常温下为固体的各种药物的溶解和释放性质; 所述链段是在常温至大约体温的温度下为液态的环氧烷链，并且所述链段含有亲水性烯化氧链和疏水环氧烷链，或者包含它们中的一种或两者，和 其中亲水部分和疏水部分以混合方式存在的氧化烯链。

公开(公告)号：US5227412A

公开(公告)日：1993-07-13

申请号：US944019

申请日：1992-09-14

申请人： Suong-Hyu Hyon ,  Yoshito Ikada ,  Yasuo Shikinami ,  Kaoru Tsuta ,  Hidekazu Boutani

发明人： Suong-Hyu Hyon ,  Yoshito Ikada ,  Yasuo Shikinami ,  Kaoru Tsuta ,  Hidekazu Boutani

IPC分类号： A61L31/06 ,  A61L31/14

CPC分类号： A61L31/148 ,  A61L31/06 ,  A61L31/14

摘要： Biodegradable and resorbable surgical materials of molded articles of poly(lactic acid) or copolymers of lactic acid and glycolic acid, characterized in that the articles are molecular-orientated, and having a bending strength of 1.6.times.10.sup.33 to 2.5.times.10.sup.3 kg/cm.sup.2, a bending modulus of 5.5.times.10.sup.2 to 24.0.times.10.sup.2 kg/cm.sup.2, a crystallinity, determined by density measurement, of 10 to 60%, and a viscosity average molecular weight measured after melt processing of not less than 200,000, and in that at least 80% of initial strength of the articles is maintained after dipping in a saline at 37.degree. C. for three months.

摘要翻译： 聚（乳酸）或乳酸和乙醇酸共聚物的可生物降解和可再吸收的外科材料，其特征在于制品是分子取向的，并且具有1.6×1033至2.5×10 3 kg / cm 2的弯曲强度， 5.5×102〜24.0×102kg / cm2的模量，通过密度测定确定的结晶度为10〜60％，熔融加工后测定的粘均分子量为20万以上，初始值为80％以上 在37℃的盐水中浸渍3个月后，保持制品的强度。