知搜-全球专利检索

  1. Login
  2. Sign Up

Search Results

64 records (took 0.038 seconds)

    Static pin insertion tool for lacrimal implant
    1.
    发明授权
    Static pin insertion tool for lacrimal implant 有权

    公开(公告)号：US11406532B2

    公开(公告)日：2022-08-09

    申请号：US16316563

    申请日：2017-07-13

    Applicant: Mati Therapeutics Inc.

    Inventor： Deepank Utkhede ,  Jon Wallace ,  Robert Williams

    IPC: A61F9/007 ,  A61F9/00 ,  A61F2/00

    Abstract: An insertion tool, systems, and methods for use with lacrimal implants are herein provided. An insertion tool is disclosed that includes an inserter tip with a static pin at a distal end configured to be placed in a bore of a lacrimal implant and a mechanical coupling to receive a handle at a proximal end of the inserter tip; and, a handle coupled to the inserter tip at a distal end of the handle and a plunger at a proximal end of the handle, wherein the plunger is configured to release the inserter tip from the handle. The static pin of the inserter tip is de-coupled from the lacrimal implant after placement in a lacrimal canaliculus without mechanical force from the insertion tool.

    Lacrimal implants and related methods
    4.
    发明授权
    Lacrimal implants and related methods 有权

    公开(公告)号：US10238535B2

    公开(公告)日：2019-03-26

    申请号：US12710855

    申请日：2010-02-23

    Applicant: Alan R. Rapacki ,  Valery Rubinchik ,  Charles Richard Kjellbotn

    Inventor： Alan R. Rapacki ,  Valery Rubinchik ,  Charles Richard Kjellbotn

    IPC: A61M31/00 ,  A61F9/007 ,  A61K9/00

    Abstract: Lacrimal implants and related methods providing secure, wedgable retention within a lacrimal punctum and associated canaliculus of an eye are disclosed. The lacrimal implants can comprise an implant body configured for at least partial insertion through the lacrimal punctum and into the canaliculus. The implant body can include first and second portions, and can extend from a proximal end of the first portion defining a longitudinal proximal axis to a distal end of the second portion defining a longitudinal distal axis. The implant body can be configured such that, when implanted using an integral dilator, an angled intersection exists between the proximal and distal axes. In this way, at least a portion of the implant body can be biased against at least a portion of the lacrimal canaliculus located at or more distal to a canalicular curvature, thereby retaining an implanted position of the lacrimal implant using anatomical structures.

    Drug Delivery Methods, Structures, and Compositions for Nasolacrimal Systems
    9.
    发明申请
    Drug Delivery Methods, Structures, and Compositions for Nasolacrimal Systems 审中-公开
    药物递送方法，结构和组合物用于鼻泪管系统

    公开(公告)号：US20150224200A1

    公开(公告)日：2015-08-13

    申请号：US14598262

    申请日：2015-01-16

    Applicant: Mati Therapeutics Inc.

    Inventor： Eugene de Juan, JR. ,  Stephen Boyd ,  Hanson S. Gifford, III ,  Mark Deem ,  Cary Reich

    IPC: A61K47/34 ,  A61K31/5575 ,  A61K9/00

    CPC classification number: A61K9/0051 ,  A61F9/0017 ,  A61F9/0026 ,  A61F9/00772 ,  A61F9/00781 ,  A61F2220/0008 ,  A61F2250/0067 ,  A61F2250/0087 ,  A61K9/00 ,  A61K9/0017 ,  A61K9/06 ,  A61K31/215 ,  A61K31/216 ,  A61K31/55 ,  A61K31/557 ,  A61K31/5575 ,  A61K31/573 ,  A61K47/34 ,  A61L31/16

    Abstract: An implant for insertion into a punctum of a patient comprises a body. The body has a distal end, a proximal end, and an axis therebetween. The distal end of the body is insertable distally through the punctum into the canalicular lumen. The body comprises a therapeutic agent included within an agent matrix drug core. Exposure of the agent matrix to the tear fluid effects an effective therapeutic agent release into the tear fluid over a sustained period. The body has a sheath disposed over the agent matrix to inhibit release of the agent away from the proximal end. The body also has an outer surface configured to engage luminal wall tissues so as to inhibit expulsion when disposed therein. In specific embodiments, the agent matrix comprises a non-bioabsorbable polymer, for example silicone in a non-homogenous mixture with the agent.

    Abstract translation: 用于插入患者的泪点的植入物包括主体。 主体具有远端，近端和它们之间的轴线。 身体的远端可通过泪点向远端插入到小管腔内。 身体包含药剂基质药物核心内的治疗剂。 试剂基质暴露于泪液能够在持续的时间内有效的治疗剂释放到泪液中。 身体具有设置在药剂基质上的护套以抑制药剂远离近端的释放。 身体还具有被配置为接合腔壁组织的外表面，以便当设置在其中时阻止排出。 在具体实施方案中，试剂基质包含非生物可吸收聚合物，例如与该试剂的非均匀混合物的硅氧烷。

Patent Agency Ranking