知搜-全球专利检索

  1. 登录
  2. 注册

搜索结果

51 条记录 (耗时 0.035 秒)

    Nucleic acids encoding respiratory syncytial virus subgroup B strain 9320
    2.
    发明授权
    Nucleic acids encoding respiratory syncytial virus subgroup B strain 9320 有权
    编码呼吸道合胞病毒亚组B菌株9320的核酸

    公开(公告)号：US08163530B2

    公开(公告)日：2012-04-24

    申请号：US12508075

    申请日：2009-07-23

    申请人： Xing Cheng ,  Hyun Jung Park ,  Hong Jin

    发明人： Xing Cheng ,  Hyun Jung Park ,  Hong Jin

    IPC分类号： C12N7/00 ,  C12N7/01 ,  C12N7/04 ,  A61K39/155

    CPC分类号： C07K14/005 ,  A61K2039/525 ,  A61K2039/5254 ,  C07K16/1027 ,  C12N2760/18522

    摘要： The complete polynucleotide sequence of the human respiratory syncytial virus subgroup B strain 9320 genome is provided. Proteins encoded by this polynucleotide sequence are also provided. Isolated or recombinant RSV (e.g., attenuated recombinant RSV), nucleic acids, and polypeptides, e.g., comprising mutations in the attachment protein G, are also provided, as are immunogenic compositions comprising such isolated or recombinant RSV, nucleic acids, and polypeptides. Related methods are also described.

    摘要翻译： 提供了人呼吸道合胞病毒亚组B株9320基因组的完整多核苷酸序列。 还提供了由该多核苷酸序列编码的蛋白质。 还提供了分离或重组的RSV（例如减毒的重组RSV），核酸和多肽，例如包含附着蛋白G中的突变，包含这种分离的或重组的RSV，核酸和多肽的免疫原性组合物也是如此。 还描述了相关方法。

    Compositions And Methods Involving Respiratory Syncytial Virus Subgroup B Strain 9320
    3.
    发明申请
    Compositions And Methods Involving Respiratory Syncytial Virus Subgroup B Strain 9320 审中-公开
    组合和方法涉及呼吸道合胞病毒亚组B菌株9320

    公开(公告)号：US20120263744A1

    公开(公告)日：2012-10-18

    申请号：US13449087

    申请日：2012-04-17

    申请人： Xing Cheng ,  Hyun Jung Park ,  Hong Jin

    发明人： Xing Cheng ,  Hyun Jung Park ,  Hong Jin

    IPC分类号： A61K39/155 ,  A61P31/14

    CPC分类号： C07K14/005 ,  A61K2039/525 ,  A61K2039/5254 ,  C07K16/1027 ,  C12N2760/18522

    摘要： The complete polynucleotide sequence of the human respiratory syncytial virus subgroup B strain 9320 genome is provided. Proteins encoded by this polynucleotide sequence are also provided. Isolated or recombinant RSV (e.g., attenuated recombinant RSV), nucleic acids, and polypeptides, e.g., comprising mutations in the attachment protein G, are also provided, as are immunogenic compositions comprising such isolated or recombinant RSV, nucleic acids, and polypeptides. Related methods are also described.

    摘要翻译： 提供了人呼吸道合胞病毒亚组B株9320基因组的完整多核苷酸序列。 还提供了由该多核苷酸序列编码的蛋白质。 还提供了分离或重组的RSV（例如减毒的重组RSV），核酸和多肽，例如包含附着蛋白G中的突变，包含这种分离的或重组的RSV，核酸和多肽的免疫原性组合物也是如此。 还描述了相关方法。

    Nucleic acids encoding respiratory syncytial virus subgroup B strain 9320
    4.
    发明授权
    Nucleic acids encoding respiratory syncytial virus subgroup B strain 9320 有权
    编码呼吸道合胞病毒亚组B菌株9320的核酸

    公开(公告)号：US07572904B2

    公开(公告)日：2009-08-11

    申请号：US10811508

    申请日：2004-03-26

    申请人： Xing Cheng ,  Hyun Jung Park ,  Hong Jin

    发明人： Xing Cheng ,  Hyun Jung Park ,  Hong Jin

    IPC分类号： C07H21/00 ,  A61K39/155

    CPC分类号： C07K14/005 ,  A61K2039/525 ,  A61K2039/5254 ,  C07K16/1027 ,  C12N2760/18522

    摘要： The complete polynucleotide sequence of the human respiratory syncytial virus subgroup B strain 9320 genome is provided. Proteins encoded by this polynucleotide sequence are also provided. Isolated or recombinant RSV (e.g., attenuated recombinant RSV), nucleic acids, and polypeptides, e.g., comprising mutations in the attachment protein G, are also provided, as are immunogenic compositions comprising such isolated or recombinant RSV, nucleic acids, and polypeptides. Related methods are also described.

    摘要翻译： 提供了人呼吸道合胞病毒亚组B株9320基因组的完整多核苷酸序列。 还提供了由该多核苷酸序列编码的蛋白质。 还提供了分离的或重组的RSV（例如，减毒的重组RSV），核酸和多肽，例如包含附着蛋白G中的突变，以及包含这种分离或重组的RSV，核酸和多肽的免疫原性组合物。 还描述了相关方法。

    METHODS AND COMPOSITIONS FOR INCREASING REPLICATION CAPACITY OF AN INFLUENZA VIRUS
    9.
    发明申请
    METHODS AND COMPOSITIONS FOR INCREASING REPLICATION CAPACITY OF AN INFLUENZA VIRUS 失效
    增加流感病毒复制能力的方法和组合物

    公开(公告)号：US20080175863A1

    公开(公告)日：2008-07-24

    申请号：US11780627

    申请日：2007-07-20

    申请人： Hong Jin ,  Bin Liu

    发明人： Hong Jin ,  Bin Liu

    IPC分类号： A61K39/145 ,  C12N15/01 ,  C12N7/00 ,  A61P31/20

    CPC分类号： C12N7/00 ,  A61K39/12 ,  A61K39/145 ,  C07K14/005 ,  C12N2760/16121 ,  C12N2760/16122 ,  C12N2760/16134

    摘要： In certain aspects, the present invention provides methods for increasing the replication capacity of influenza viruses in hens' eggs and/or cell culture, recombinant and/or reassortant influenza viruses with increased replication capacity, and immunogenic and vaccine compositions comprising such recombinant and/or reassortant influenza viruses. In other aspects, the invention further provides nucleic acids encoding influenza genes associated with increased replication capacity, expression vectors comprising the nucleic acids of the invention, methods for making influenza viruses with increased replication capacity, and kits useful for practice of the methods.

    摘要翻译： 在某些方面，本发明提供了增加在具有增加的复制能力的母鸡卵和/或细胞培养物，重组和/或重配流感病毒中的流感病毒的复制能力的方法，以及包含这种重组和/或 重配流感病毒。 在其它方面，本发明还提供编码与增加的复制能力相关的流感基因的核酸，包含本发明的核酸的表达载体，具有增加的复制能力的制备流感病毒的方法，以及可用于实施该方法的试剂盒。