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公开(公告)号：US20230154001A1
公开(公告)日：2023-05-18
申请号：US18151114
申请日：2023-01-06
CPC分类号： G06T7/0012 , A61B8/485 , A61B8/4444 , A61B8/469 , A61B8/4483 , G06T2207/10028 , G06T2207/30068 , G06T2207/10101 , G06T2207/10088 , G06T2207/10132 , G06T2207/30056
摘要： Within the field of elastography, a new approach analyzes the limiting case of shear waves established as a reverberant field. In this framework, it is assumed that a distribution of shear waves exists, oriented across all directions in 3D (e.g 2D space+time). The simultaneous multi-frequency application of reverberant shear wave fields can be accomplished by applying an array of external sources that can be excited by multiple frequencies within a bandwidth, for example 50, 100, 150, . . . 500 Hz, all contributing to the shear wave field produced in the liver or other target organ. This enables the analysis of the dispersion of shear wave speed as it increases with frequency, indicating the viscoelastic and lossy nature of the tissue under study. Furthermore, dispersion images can be created and displayed alongside the shear wave speed images. Studies on breast and liver tissues using the multi-frequency reverberant shear wave technique, employing frequencies up to 700 Hz in breast tissue, and robust reverberant patterns of shear waves across the entire liver and kidney in obese patients are reported. Dispersion images are shown to have contrast between tissue types and with quantitative values that align with previous studies.
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公开(公告)号：US11995829B2
公开(公告)日：2024-05-28
申请号：US18151114
申请日：2023-01-06
CPC分类号： G06T7/0012 , A61B8/4444 , A61B8/4483 , A61B8/469 , A61B8/485 , G06T2207/10028 , G06T2207/10088 , G06T2207/10101 , G06T2207/10132 , G06T2207/30056 , G06T2207/30068
摘要： Within the field of elastography, a new approach analyzes the limiting case of shear waves established as a reverberant field. In this framework, it is assumed that a distribution of shear waves exists, oriented across all directions in 3D (e.g. 2D space+time). The simultaneous multi-frequency application of reverberant shear wave fields can be accomplished by applying an array of external sources that can be excited by multiple frequencies within a bandwidth, for example 50, 100, 150, . . . 500 Hz, all contributing to the shear wave field produced in the liver or other target organ. This enables the analysis of the dispersion of shear wave speed as it increases with frequency, indicating the viscoelastic and lossy nature of the tissue under study. Furthermore, dispersion images can be created and displayed alongside the shear wave speed images. Studies on breast and liver tissues using the multi-frequency reverberant shear wave technique, employing frequencies up to 700 Hz in breast tissue, and robust reverberant patterns of shear waves across the entire liver and kidney in obese patients are reported. Dispersion images are shown to have contrast between tissue types and with quantitative values that align with previous studies.
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公开(公告)号：US11562483B2
公开(公告)日：2023-01-24
申请号：US16903569
申请日：2020-06-17
摘要： Within the field of elastography, a new approach analyzes the limiting case of shear waves established as a reverberant field. In this framework, it is assumed that a distribution of shear waves exists, oriented across all directions in 3D (e.g. 2D space+time). The simultaneous multi-frequency application of reverberant shear wave fields can be accomplished by applying an array of external sources that can be excited by multiple frequencies within a bandwidth, for example 50, 100, 150, . . . 500 Hz, all contributing to the shear wave field produced in the liver or other target organ. This enables the analysis of the dispersion of shear wave speed as it increases with frequency, indicating the viscoelastic and lossy nature of the tissue under study. Furthermore, dispersion images can be created and displayed alongside the shear wave speed images. Studies on breast and liver tissues using the multi-frequency reverberant shear wave technique, employing frequencies up to 700 Hz in breast tissue, and robust reverberant patterns of shear waves across the entire liver and kidney in obese patients are reported. Dispersion images are shown to have contrast between tissue types and with quantitative values that align with previous studies.
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公开(公告)号：US11678801B2
公开(公告)日：2023-06-20
申请号：US16838875
申请日：2020-04-02
CPC分类号： A61B5/0066 , A61B5/0042 , A61B5/0051 , A61B5/0055 , A61B5/0068 , A61B5/441 , G02B6/4215 , G02B21/006 , G02B21/0028 , G02B21/0036 , G02B21/0076 , G02B21/365 , G06T7/0012 , A61B5/7257 , A61B2562/0242 , G06T2207/30016 , G06T2207/30041 , G06T2207/30088
摘要： a) A Gabor domain optical coherence microscopy (GD-OCM) system providing high resolution of structural and motion imaging of objects such as tissues is combined with the use of reverberant shear wave fields (RevSW) or longitudinal shear waves (LSW) and two novel mechanical excitation sources: a coaxial coverslip excitation (CCE) and a multiple pronged excitation (MPE) sources providing structured and controlled mechanical excitation in tissues and leading to accurate derivation of elastographic properties. Alternatively, general optical computed tomography (OCT) is combined with RevSW or LWC in the object to derive elastographic properties. The embodiments include (a) GD-OCM with RevSW; (b) GD-OCM with LSW; (c) General OCT with RevSW; and General OCT with LSW.
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