公开(公告)号：US10078123B2

公开(公告)日：2018-09-18

申请号：US15301872

申请日：2015-04-17

申请人： THE GENERAL HOSPITAL CORPORATION

发明人： Phillip Zhe Sun

IPC分类号： G01V3/00 ,  G01R33/563 ,  A61B5/055 ,  A61B5/00 ,  G01R33/565 ,  G01R33/56

CPC分类号： G01R33/56341 ,  A61B5/0042 ,  A61B5/0055 ,  A61B5/055 ,  G01R33/5608 ,  G01R33/565

摘要： A system and method acquiring images of a region of interest (ROI) of a subject using a magnetic resonance imaging system. The system or method are capable of acquiring pathological data from tissue in the ROI believed to be pathological tissue and acquiring baseline data from tissue in the subject believed to not be pathological tissue. The system or method are also capable of determining correlation parameters from baseline data, generating corrected data using the baseline correlation parameters to correct the pathological data at least for intrinsic heterogeneity, and generating a report using the corrected data.

公开(公告)号：US09987402B2

公开(公告)日：2018-06-05

申请号：US14946468

申请日：2015-11-19

申请人： Smith & Nephew PLC

发明人： Edward Hartwell

IPC分类号： A61M5/00 ,  A61M1/00 ,  A61B5/107 ,  A61B5/00 ,  A61F13/00 ,  A61M25/00 ,  A61M35/00

CPC分类号： A61M1/0025 ,  A61B5/0055 ,  A61B5/107 ,  A61B5/1073 ,  A61B5/445 ,  A61B5/6843 ,  A61B5/7278 ,  A61B5/742 ,  A61F13/00 ,  A61M1/0088 ,  A61M2205/15 ,  A61M2205/18 ,  A61M2205/3331 ,  A61M2205/3344 ,  A61M2205/50 ,  A61M2230/00

摘要： A method and apparatus for measuring a volume of a wound are described, the method comprising the steps of: applying a dressing over a wound, the volume of which is to be measured, the dressing including at least a sealing drape over the wound so as to create a sealed wound cavity; creating a vacuum in said wound cavity by vacuum pump means so as to produce a predetermined vacuum in the wound cavity; measuring a volume of air extracted from said wound cavity in producing said predetermined vacuum; and, calculating a volume of said wound.

公开(公告)号：US09636019B2

公开(公告)日：2017-05-02

申请号：US13878297

申请日：2011-10-06

申请人： Talma Hendler ,  Mordekhay Medvedovsky ,  Andrey Zhdanov ,  Ilana Klovatch ,  Firas Fahoum

发明人： Talma Hendler ,  Mordekhay Medvedovsky ,  Andrey Zhdanov ,  Ilana Klovatch ,  Firas Fahoum

IPC分类号： A61B5/05 ,  A61B5/00 ,  A61B5/0476 ,  A61B5/0478

CPC分类号： A61B5/0055 ,  A61B5/0476 ,  A61B5/0478 ,  A61B2562/222

摘要： A device is presented for use in an EEG measurement performed in the presence of a magnetic field. The device includes a wiring array for connecting an electrodes arrangement to an electroencephalogram (EEG) monitoring device. The wiring array includes sampling lines arranged to form first and second groups of sampling lines, arranged in a spaced-apart substantially parallel relationship extending along first and second axes respectively, at least some of the sampling lines being wire bundles including a plurality of wires for connecting to a corresponding plurality of electrodes of the EEG electrodes arrangement; the first and second groups of sampling lines intersect with each other to form a net structure when placed on area of measurement. The wiring array thereby enable generation of EEG data characterized by reduced motion artifact and/or reduced gradient artifact associated with the presence of the magnetic field during the EEG measurement.

公开(公告)号：US07613488B1

公开(公告)日：2009-11-03

申请号：US10745234

申请日：2003-12-22

申请人： George N. Maracas ,  Romuald Pawluczyk ,  Duncan MacIntyre ,  Bronislaw Bednarz ,  Darin L. Farrelly ,  Chris Sterne ,  Ash Kaushal ,  Mang Li ,  Kenneth Anthony Morand

发明人： George N. Maracas ,  Romuald Pawluczyk ,  Duncan MacIntyre ,  Bronislaw Bednarz ,  Darin L. Farrelly ,  Chris Sterne ,  Ash Kaushal ,  Mang Li ,  Kenneth Anthony Morand

IPC分类号： A61B5/1455

CPC分类号： A61B5/14546 ,  A61B5/0053 ,  A61B5/0055 ,  A61B5/14532 ,  A61B2560/0252

摘要： The present invention provides a method for measuring a blood analyte concentration of a body part comprising removing a portion or all of the blood from the body part to produce a modified body part, and recording a first absorbance value of the modified body part. This is followed by filling the body part with blood to produce a filled body part, and recording a second absorbance value of the filled body part. A difference spectrum is obtained by subtracting the first absorbance values from the second absorbance values, and a calibration algorithm for the blood analyte is applied to the difference spectrum, thereby measuring the concentration of the blood analyte. Also provided is an apparatus for determining the concentration of a blood analyte of a body part. The apparatus comprising a chamber of a size and shape to receive the body part, where the chamber comprises an element for withdrawing and reintroducing blood from the body part, when the body part is inserted within the chamber. The chamber also comprising one or more than one port for introducing electromagnetic radiation into the chamber and onto that body part, and collecting remaining electromagnetic radiation following interaction with the body part.

摘要翻译： 本发明提供一种用于测量身体部位的血液分析物浓度的方法，包括从身体部位除去一部分或全部血液以产生修饰体部，并记录修饰体部的第一吸光度值。 随后用血液填充身体部分以产生填充体部分，并记录填充体部分的第二吸光度值。 通过从第二吸光度值减去第一吸光度值获得差分光谱，并且将血液分析物的校准算法应用于差分光谱，从而测量血液分析物的浓度。 还提供了一种用于确定身体部位的血液分析物的浓度的装置。 所述装置包括容纳身体部分的尺寸和形状的腔室，其中当所述身体部分插入所述腔室内时，所述腔室包括用于从所述身体部分抽出并再次引入血液的元件。 所述腔室还包括一个或多于一个端口，用于将电磁辐射引入所述腔室并且到达所述身体部分，并且在与身体部位相互作用之后收集剩余的电磁辐射。

公开(公告)号：US20080087098A1

公开(公告)日：2008-04-17

申请号：US11906198

申请日：2007-10-01

申请人： Di Qu ,  Gurinder Paul S. Seehra ,  Christopher J. Masotti

发明人： Di Qu ,  Gurinder Paul S. Seehra ,  Christopher J. Masotti

IPC分类号： G01N3/20

CPC分类号： A61B5/442 ,  A61B5/0055 ,  A61B5/0088

摘要： The invention relates to methods of measuring the overall elasticity of skin and determining the portion of the overall elasticity that is due to elastic properties and the portion of overall elasticity that is due to viscoelastic properties of the skin and correlating the results of the measurement to an individual's chronological age. The invention also relates to methods of measuring improvements in a person's skin health by measuring elasticity before, during and after human clinical trials of topical and/or oral treatment compositions. The parameters for determining elasticity are based on areas that are defined on a deformation/relaxation curve and require that an inflection point be determined for each skin sample analyzed.

摘要翻译： 本发明涉及测量皮肤整体弹性的方法，并确定由于弹性和弹性部分所引起的整体弹性的部分，这是由于皮肤的粘弹性，并将测量结果与 个人的年龄。 本发明还涉及通过在局部和/或口服治疗组合物的人临床试验之前，期间和之后测量弹性来测量人的皮肤健康改善的方法。 用于确定弹性的参数基于在变形/松弛曲线上定义的区域，并且要求为分析的每个皮肤样品确定拐点。

公开(公告)号：US09724004B2

公开(公告)日：2017-08-08

申请号：US13575740

申请日：2011-01-28

申请人： Tapani Taskinen ,  Aki Backman

发明人： Tapani Taskinen ,  Aki Backman

IPC分类号： A61B5/03 ,  A61B5/00

CPC分类号： A61B5/03 ,  A61B5/0055 ,  A61B5/441 ,  A61B5/4878

摘要： The method facilitates measuring of a tissue pressure non-invasively utilizing a negative pressure. The device has a pressure chamber, pressure sensor for measuring the pressure in the pressure chamber and a range sensor for measuring the skin tissue rising caused by the negative pressure.

公开(公告)号：US20160078604A1

公开(公告)日：2016-03-17

申请号：US14784963

申请日：2014-04-15

申请人： THE JOHNS HOPKINS UNIVERSITY

发明人： Liheng Guo ,  Daniel A. Herzka

IPC分类号： G06T5/00 ,  G06T7/20 ,  A61B5/00 ,  G01R33/567 ,  G01R33/565 ,  G06T7/00 ,  G01R33/56

CPC分类号： G06T5/002 ,  A61B5/0055 ,  A61B5/055 ,  A61B5/7207 ,  A61B5/721 ,  G01R33/5602 ,  G01R33/56509 ,  G01R33/5676 ,  G06T7/0012 ,  G06T7/207 ,  G06T2207/10088 ,  G06T2207/30048 ,  G06T2207/30092

摘要： An embodiment in accordance with the present invention provides concurrent measurement of motion during T2-weighted magnetic resonance imaging. The present invention combines T2 preparation, a module used to impart T2 contrast, and motion measurement, tracking, and/or correction. The present invention provides for the expedition of more efficient motion compensation during T2-weighted imaging. The proposed invention can be used to provide a variety of measurements of motion, with no overhead in imaging time. The proposed invention also enables T2 contrast imaging to be executed while a subject is breathing freely, without the additional time cost associated with the standard motion tracking methodologies.

摘要翻译： 根据本发明的实施例提供了T2加权磁共振成像期间的运动的并行测量。 本发明组合了T2准备，用于赋予T2对比度的模块以及运动测量，跟踪和/或校正。 本发明提供了在T2加权成像期间考察更有效的运动补偿。 所提出的发明可用于提供各种运动测量，在成像时间内没有开销。 所提出的发明还能够在受试者自由呼吸时执行T2对比度成像，而不需要与标准运动跟踪方法相关联的附加时间成本。

公开(公告)号：US09265461B2

公开(公告)日：2016-02-23

申请号：US12872643

申请日：2010-08-31

申请人： Ian W. Hunter ,  Yi Chen ,  Lynette A. Jones ,  N. Catherine Hogan

发明人： Ian W. Hunter ,  Yi Chen ,  Lynette A. Jones ,  N. Catherine Hogan

IPC分类号： A61B5/103 ,  A61B9/00 ,  A61B5/00

CPC分类号： A61B5/442 ,  A61B5/0048 ,  A61B5/0051 ,  A61B5/0053 ,  A61B5/0055 ,  A61B5/0057 ,  A61B5/441 ,  A61B5/6824 ,  A61B9/00

摘要： A method for testing the effect of a skin care product includes measuring a mechanical property of skin tissue using nonlinear stochastic system identification, applying the product to the skin, repeating the measurement of the mechanical property after the application of the product, and comparing the before and after measurements to quantify the effect of the product.Measuring the mechanical property of the skin can include placing a probe against a surface of the skin, perturbing the skin with the probe using a stochastic sequence, and measuring the response of the skin to the perturbation. Perturbing the skin can include indenting the skin with the probe, extending the skin with the probe, and sliding the probe across the skin surface. The mechanical property may be indicative of skin compliance, skin elasticity, skin stiffness, or skin damping. The mechanical property can be dependent on perturbation depth and may be measured at a plurality of anatomical locations.

摘要翻译： 用于测试皮肤护理产品的效果的方法包括使用非线性随机系统识别来测量皮肤组织的机械性质，将产品施用于皮肤，重复产品施用后的机械性能的测量，并比较之前 并经过测量以量化产品的影响。 测量皮肤的机械性能可以包括将探针放置在皮肤表面上，使用随机序列用探针扰动皮肤，以及测量皮肤对扰动的反应。 刺激皮肤可以包括使用探针压伤皮肤，用探头延伸皮肤，并将探头滑过皮肤表面。 机械性能可以指示皮肤顺应性，皮肤弹性，皮肤刚度或皮肤阻滞。 机械性能可以取决于扰动深度，并且可以在多个解剖位置处测量。

公开(公告)号：US08814841B2

公开(公告)日：2014-08-26

申请号：US12746492

申请日：2008-10-07

申请人： Edward Hartwell

发明人： Edward Hartwell

IPC分类号： A61M1/00

CPC分类号： A61M1/0025 ,  A61B5/0055 ,  A61B5/107 ,  A61B5/1073 ,  A61B5/445 ,  A61B5/6843 ,  A61B5/7278 ,  A61B5/742 ,  A61F13/00 ,  A61M1/0088 ,  A61M2205/15 ,  A61M2205/18 ,  A61M2205/3331 ,  A61M2205/3344 ,  A61M2205/50 ,  A61M2230/00

摘要： A method and apparatus for measuring a volume of a wound are described, the method comprising the steps of: applying a dressing over a wound, the volume of which is to be measured, the dressing including at least a sealing drape over the wound so as to create a sealed wound cavity; creating a vacuum in said wound cavity by vacuum pump means so as to produce a predetermined vacuum in the wound cavity; measuring a volume of air extracted from said wound cavity in producing said predetermined vacuum; and, calculating a volume of said wound.

摘要翻译： 描述了一种用于测量伤口体积的方法和装置，所述方法包括以下步骤：将敷料涂抹在要测量的体积的伤口上，所述敷料至少包括在伤口上的密封盖，以便 创造一个密封的伤口腔; 通过真空泵装置在所述伤口腔中产生真空，以在伤口腔中产生预定的真空; 测量在产生所述预定真空时从所述伤口腔抽出的空气体积; 以及计算所述伤口的体积。

公开(公告)号：US20110313289A1

公开(公告)日：2011-12-22

申请号：US13201156

申请日：2010-02-11

申请人： Gangming Luo ,  Jonathan J. Kaufman

发明人： Gangming Luo ,  Jonathan J. Kaufman

IPC分类号： A61B5/103 ,  G01N23/06 ,  A61B8/00

CPC分类号： A61B8/0875 ,  A61B5/00 ,  A61B5/0055 ,  A61B6/00 ,  A61B8/4209

摘要： An invention is disclosed for locating a region of interest (ROI) in the radius. A method and apparatus are disclosed that use a pair of ultrasound transducers for ultrasound assessment of various properties of bone. The invention includes positioning the transducers on the anterior-posterior (dorsal and ventral) sides of a forearm of an individual. The positioning is based on the forearm length, and a selected percentage of this length at which the ROI is desired. In a presently preferred embodiment of the invention, the ROI is defined as the ⅓rd location. An arm is placed in an ultrasound fixture which has a first surface, a second surface with a raised portion against which the ulna styloid process is placed, and a third surface on which the elbow is placed. The distance between the raised portion of the second surface and the centerlines of the pair of ultrasound transducers is adjustable. The positioning so obtained leads to the ability to make both (i) reproducible measurements and (ii) to be able to compare the results obtained in one person with another, because relatively analogous portions of the radii are assessed in both. In an alternative embodiment of the invention, a single transducer is positioned similarly on the forearm, operating in pulse-echo mode.

摘要翻译： 公开了一种用于在半径中定位感兴趣区域（ROI）的发明。 公开了一种使用一对超声波换能器来超声评估骨骼各种性质的方法和装置。 本发明包括将换能器定位在个体前臂的前 - 后（背侧和腹侧）侧。 定位是基于前臂长度，以及期望ROI的长度的选定百分比。 在本发明的当前优选实施例中，ROI被定义为第1/3位置。 手臂放置在具有第一表面的超声波固定器中，具有突出部分的第二表面，尺骨乳突过程被放置在其上，第三表面设置有肘部。 第二表面的凸起部分与一对超声换能器的中心线之间的距离是可调节的。 如此获得的定位使得能够使（i）可再现的测量和（ii）能够将在一个人中获得的结果与另一个人的结果进行比较，因为在两者中评估半径的相对类似的部分。 在本发明的替代实施例中，单个换能器类似地定位在前臂上，以脉冲回波模式操作。