公开(公告)号：US20180228198A1

公开(公告)日：2018-08-16

申请号：US15432803

申请日：2017-02-14

申请人： UNIVERSITY OF SOUTHERN CALIFORNIA

发明人： SEBASTIAN BRANDHORST ,  VALTER D. LONGO ,  MIN WEI

IPC分类号： A23L33/00 ,  A23L33/15 ,  A23L33/155 ,  A23L33/16 ,  A23L23/10 ,  A23L2/52 ,  A23F3/40

CPC分类号： A23L33/40 ,  A23F3/40 ,  A23L2/38 ,  A23L2/52 ,  A23L19/05 ,  A23L23/00 ,  A23L23/10 ,  A23L25/30 ,  A23L33/115 ,  A23L33/15 ,  A23L33/155 ,  A23L33/16 ,  A23L33/30 ,  A23V2002/00 ,  A61K36/00 ,  A61K2300/00

摘要： A fasting mimicking diet package providing daily meal portions for a predetermined number of days is provided. The fasting mimicking diet package includes a kale cracker composition, a first vegetable broth composition, a mushroom soup composition, a tomato soup composition, a quinoa-containing minestrone soup composition, a bean-containing minestrone soup composition, and a pumpkin soup composition. Characteristically, the daily meal portions are packaged into meal servings or into a total daily serving to be divided into meals.

公开(公告)号：US20210161191A1

公开(公告)日：2021-06-03

申请号：US17176750

申请日：2021-02-16

申请人： UNIVERSITY OF SOUTHERN CALIFORNIA

发明人： VALTER D. LONGO ,  SEBASTIAN BRANDHORST ,  MIN WEI

IPC分类号： A23L33/00 ,  A23L33/20

摘要： Methods for lowering hypertension, elevated total cholesterol, elevated glucose and insulin, elevated IGF-1, elevated triglyceride levels, and/or elevated CRP levels, and elevated liver fat without negatively affecting or lowering the levels of these markers/factors in subjects with already low levels of these markers are provided. A method for elevating stem cells and regeneration and anti-inflammatory agents is also provided. Finally, a method for treating metabolic syndrome is also provided. A hypocaloric or calorie free diet or a fasting mimicking diet is administered for a first time period to the subject to reduce blood pressure or the levels of the above markers/risk factors for aging and age-related diseases.

公开(公告)号：US20170035093A1

公开(公告)日：2017-02-09

申请号：US15297672

申请日：2016-10-19

申请人： UNIVERSITY OF SOUTHERN CALIFORNIA

发明人： VALTER D. LONGO ,  CHIA-WEI CHENG ,  SEBASTIAN BRANDHORST ,  MIN WEI

IPC分类号： A23L33/00 ,  A23L33/16 ,  A23L33/15 ,  A23L33/17 ,  A23L33/115 ,  A23L33/155

CPC分类号： A23L33/40 ,  A23L29/37 ,  A23L33/115 ,  A23L33/15 ,  A23L33/155 ,  A23L33/16 ,  A23L33/17 ,  A23L33/175 ,  A23L33/30 ,  A23V2002/00 ,  A61K45/00

摘要： A method includes a step of identifying a subject in need of diet modification; and administering a first diet to the subject for a first time period. The first diet provides 4.5 to 7 kilocalories per pound of subject for a first day and 3 to 5 kilocalories per pound of subject per day for a second to fifth day of the first diet. The first diet includes less than 30 g of sugar on the first day; less than 20 g of sugar on the second to fifth days; less than 28 g of proteins on the first day; less than 18 g of proteins on days the second to fifth days; 20 to 30 grams of monounsaturated fats on the first day; 10 to 15 grams of monounsaturated fats on the second to fifth days; and between 6 and 10 grams of polyunsaturated fats on the first day.

摘要翻译： 一种方法包括识别需要饮食修饰的受试者的步骤; 以及对所述受试者施用第一次饮食第一次。 第一次饮食在头一天的第二天至第五天每天每磅主题每天提供4.5至7千卡每天的主题，每天每磅3至5千卡。 第一天的饮食包括第一天少于30克的糖; 第二至第五天少于20克糖; 第一天少于28克蛋白质; 第二至第五天天数少于18克; 第一天20至30克单不饱和脂肪; 第二至第五天10至15克单不饱和脂肪; 和第一天6至10克多不饱和脂肪之间。

公开(公告)号：US20160324193A1

公开(公告)日：2016-11-10

申请号：US15148251

申请日：2016-05-06

申请人： UNIVERSITY OF SOUTHERN CALIFORNIA

发明人： VALTER D. LONGO ,  SEBASTIAN BRANDHORST ,  MIN WEI

IPC分类号： A23K1/18

CPC分类号： A23L33/30 ,  A23L33/20 ,  A23L33/40

摘要： Methods for lowering hypertension, elevated total cholesterol, elevated glucose and insulin, elevated IGF-1, elevated triglyceride levels, and/or elevated CRP levels, and elevated liver fat without negatively affecting or lowering the levels of these markers/factors in subjects with already low levels of these markers are provided. A method for elevating stem cells and regeneration and anti-inflammatory agents is also provided. Finally, a method for treating metabolic syndrome is also provided. A hypocaloric or calorie free diet or a fasting mimicking diet is administered for a first time period to the subject to reduce blood pressure or the levels of the above markers/risk factors for aging and age-related diseases.

摘要翻译： 降低高血压，升高的总胆固醇，升高的葡萄糖和胰岛素的方法，升高的IGF-1，升高的甘油三酯水平和/或升高的CRP水平，和升高的肝脏脂肪，而不会对已经存在的受试者的这些标记/因子的水平产生负面影响或降低 提供了这些标记的低水平。 还提供了提高干细胞和再生抗炎剂的方法。 最后，还提供了一种治疗代谢综合征的方法。 对受试者第一次施用低热量或卡路里饮食或禁食模拟饮食以降低血压或上述标记物的水平/老化和与年龄有关的疾病的危险因素。