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公开(公告)号：US20220034785A1
公开(公告)日：2022-02-03
申请号：US17275994
申请日：2019-09-16
摘要： A cell sorting system is provided to comprise: an imaging device including abeam scanner scanning abeam along a first direction to obtain a cell image data including fluorescent information or cell image information of a cell, the beam applied to the cell flowing in a channel along a second direction with an angle to the first direction; a data processing and control device in communication with the imaging device, the data processing and control device including a processor configured to process the cell image data obtained by the imaging device to determine one or more properties associated with the cell from the processed cell image data and to produce a control command based on a comparison of the determined one or more properties with a sorting criteria, and a cell sorting device in communication with the imaging device and the data processing and control device.
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公开(公告)号：US20190302000A1
公开(公告)日：2019-10-03
申请号：US16307449
申请日：2017-06-09
发明人： Yu-Hwa Lo , Yuanyuan Han , Yi Gu , Ce Zhang
摘要： Disclosed are systems, devices and methods for imaging and image-based sorting of particles in a flow system, including cells in a flow cytometer. In some aspects, a system includes a particle flow device to flow particles through a channel, an imaging system to obtain image data of a particle during flow through the channel, a processing unit to determine a property associated with the particle and to produce a control command for sorting the particle based on sorting criteria associated with particle properties, and an actuator to direct the particle into one of a plurality of output paths of the particle flow device in real-time.
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公开(公告)号：US20230384208A1
公开(公告)日：2023-11-30
申请号：US18295244
申请日：2023-04-03
发明人： Yu-Hwa Lo , Yuanyuan Han , Yi Gu , Ce Zhang
CPC分类号： G01N15/1475 , G01J3/51 , G01N15/1429 , G01N15/147 , G01N15/1484 , G01J3/0229 , G01J3/36 , G01J3/0208 , G01J3/46 , G01J3/4406 , G01N2015/1006
摘要： Disclosed are systems, devices and methods for imaging and image-based sorting of particles in a flow system, including cells in a flow cytometer. In some aspects, a system includes a particle flow device to flow particles through a channel, an imaging system to obtain image data of a particle during flow through the channel, a processing unit to determine a property associated with the particle and to produce a control command for sorting the particle based on sorting criteria associated with particle properties, and an actuator to direct the particle into one of a plurality of output paths of the particle flow device in real-time.
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公开(公告)号：US11016017B2
公开(公告)日：2021-05-25
申请号：US16307449
申请日：2017-06-09
发明人： Yu-Hwa Lo , Yuanyuan Han , Yi Gu , Ce Zhang
摘要： Disclosed are systems, devices and methods for imaging and image-based sorting of particles in a flow system, including cells in a flow cytometer. In some aspects, a system includes a particle flow device to flow particles through a channel, an imaging system to obtain image data of a particle during flow through the channel, a processing unit to determine a property associated with the particle and to produce a control command for sorting the particle based on sorting criteria associated with particle properties, and an actuator to direct the particle into one of a plurality of output paths of the particle flow device in real-time.
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公开(公告)号：US11668641B2
公开(公告)日：2023-06-06
申请号：US17326312
申请日：2021-05-20
发明人： Yu-Hwa Lo , Yuanyuan Han , Yi Gu , Ce Zhang
CPC分类号： G01N15/1475 , G01J3/0208 , G01J3/0229 , G01J3/36 , G01J3/4406 , G01J3/46 , G01J3/51 , G01N15/147 , G01N15/1429 , G01N15/1484 , G01N2015/1006 , G01N2015/1402 , G01N2015/149 , G01N2015/1497
摘要： Disclosed are systems, devices and methods for imaging and image-based sorting of particles in a flow system, including cells in a flow cytometer. In some aspects, a system includes a particle flow device to flow particles through a channel, an imaging system to obtain image data of a particle during flow through the channel, a processing unit to determine a property associated with the particle and to produce a control command for sorting the particle based on sorting criteria associated with particle properties, and an actuator to direct the particle into one of a plurality of output paths of the particle flow device in real-time.
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公开(公告)号：US20220011216A1
公开(公告)日：2022-01-13
申请号：US17326312
申请日：2021-05-20
发明人： Yu-Hwa Lo , Yuanyuan Han , Yi Gu , Ce Zhang
摘要： Disclosed are systems, devices and methods for imaging and image-based sorting of particles in a flow system, including cells in a flow cytometer. In some aspects, a system includes a particle flow device to flow particles through a channel, an imaging system to obtain image data of a particle during flow through the channel, a processing unit to determine a property associated with the particle and to produce a control command for sorting the particle based on sorting criteria associated with particle properties, and an actuator to direct the particle into one of a plurality of output paths of the particle flow device in real-time.
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