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1.发明授权Bandpass filter, wireless communication module and wireless communication device 有权带通滤波器，无线通信模块和无线通信设备公开(公告)号：US08493163B2
公开(公告)日：2013-07-23
申请号：US12567693
申请日：2009-09-25
申请人： Takanori Kubo , Hiromichi Yoshikawa
发明人： Takanori Kubo , Hiromichi Yoshikawa
CPC分类号： H01P1/20327 , H01P1/20354
摘要： A bandpass filter for a wide frequency band such as UWB is disclosed. The bandpass filter can receive a pair of signals, namely a balanced signal, and output a pair of signals. The bandpass filter comprises a plurality of ½ wavelength resonance electrodes, a plurality of ¼ wavelength resonance electrodes and a plurality of coupling electrodes. A transmission characteristic of the bandpass filter having flat and low loss over the entire region of the broad pass band can be achieved.
摘要翻译： 公开了一种用于诸如UWB的宽频带的带通滤波器。 带通滤波器可以接收一对信号，即平衡信号，并输出一对信号。 带通滤波器包括多个1/2波长谐振电极，多个1/4波长谐振电极和多个耦合电极。 可以实现在宽带的整个区域上具有平坦且低损耗的带通滤波器的传输特性。
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2.发明授权Bandpass filter, wireless communication module and wireless communication device 有权带通滤波器，无线通信模块和无线通信设备公开(公告)号：US08497748B2
公开(公告)日：2013-07-30
申请号：US12580944
申请日：2009-10-16
申请人： Takanori Kubo , Hiromichi Yoshikawa
发明人： Takanori Kubo , Hiromichi Yoshikawa
IPC分类号： H01P1/203
CPC分类号： H01P1/20345
摘要： A bandpass filter for a wide frequency band such as UWB is disclosed. The bandpass filter can receive a pair of signals, namely a differential signal, and output a single signal, namely an unbalanced signal. A transmission characteristic of the bandpass filter having an attenuation pole near both sides of the passband can be achieved.
摘要翻译： 公开了一种用于诸如UWB的宽频带的带通滤波器。 带通滤波器可以接收一对信号，即差分信号，并输出单个信号，即不平衡信号。 可以实现具有靠近通带两侧的衰减极的带通滤波器的传输特性。
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3.发明授权
公开(公告)号：US5474834A
公开(公告)日：1995-12-12
申请号：US257486
申请日：1994-06-09
IPC分类号： H01L23/498 , B32B9/00
CPC分类号： H01L23/49888 , H01L2924/0002 , Y10S428/901 , Y10S428/93 , Y10S505/812 , Y10S505/813 , Y10T428/24917 , Y10T428/24926
摘要： A circuit sub-assembly as a mounting for an electronic component such as Josephson device, i.e., a superconducting element, comprises a ceramic insulating substrate, an oxygen-shielding barrier layer formed on the insulating substrate, and a circuit film of niobium, as a superconducting material formed on the barrier layer according to a desired pattern. The barrier layer prevents oxidation of the circuit layer by shielding it from oxygen present in the insulating substrate. Due to the barrier layer, the circuit film is scarcely subject to superconductivity-impairing oxidation. The circuit film is thus capable of high-speed electronic signal conduction.
摘要翻译： 作为用于诸如约瑟夫逊装置的电子部件的安装的电路子组件，即超导元件，包括陶瓷绝缘基板，形成在绝缘基板上的氧屏蔽阻挡层和铌的电路膜，作为 超导材料根据期望的图案形成在阻挡层上。 阻挡层通过屏蔽绝缘基板中存在的氧来防止电路层的氧化。 由于阻挡层，电路膜几乎不受超导损害氧化的影响。 因此，电路膜能够进行高速电子信号传导。
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4.发明申请公开(公告)号：US20100298411A1
公开(公告)日：2010-11-25
申请号：US12738797
申请日：2008-10-24
IPC分类号： A61K31/713 , C07H21/02 , C12N15/113 , A61P5/00
CPC分类号： A61K47/48038 , A61K47/542 , A61K47/543
摘要： An object of the present invention is to provide a novel double-stranded RNA that has high nuclease resistance and high cellular uptake efficiency, and that is capable of producing an excellent RNA interference effect. The present invention provides a lipid-modified double-stranded RNA comprising a sense strand having a nucleotide sequence complementary to a target sequence, and an antisense strand having a nucleotide sequence complementary to the sense strand, the double-stranded RNA being capable of inhibiting the expression of the target gene, the sense strand having a lipid linked to at least one of the first to sixth nucleotides from the 5′ end side directly or via a linker.
摘要翻译： 本发明的目的是提供具有高核酸酶抗性和高细胞摄取效率的新型双链RNA，并能够产生优异的RNA干扰效果。 本发明提供脂质修饰的双链RNA，其包含具有与靶序列互补的核苷酸序列的有义链和具有与有义链互补的核苷酸序列的反义链，所述双链RNA能够抑制 靶基因的表达，有义链具有从5'末端侧的至少一个第一至第六个核苷酸直接或通过连接体连接的脂质。
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公开(公告)号：US10738304B2
公开(公告)日：2020-08-11
申请号：US12808504
申请日：2008-12-18
申请人： Takanori Kubo , Hideki Ohba , Kazuo Sakurai , Jusaku Minari , Atsushi Uno
发明人： Takanori Kubo , Hideki Ohba , Kazuo Sakurai , Jusaku Minari , Atsushi Uno
摘要： An object of the present invention is to provide novel double-stranded RNA having an RNA interference effect, in which the cellular uptake and the resistance to enzymatic degradation are improved, without reducing the RNA interference effect.The cellular uptake and the resistance to enzymatic degradation of a complex of a polysaccharide having a β-1,3-glucan skeleton and double-stranded RNA can be significantly improved while maintaining the RNA interference effect, by fulfilling the following conditions (i) to (iii): (i) the double-stranded RNA has a sense strand consisting of a base sequence complementary to a target sequence in a target gene and an antisense strand containing a base sequence complementary to the sense strand, and the double-stranded RNA can inhibit expression of the target gene; (ii) the double-stranded RNA has a single-stranded polydeoxyadenine bound directly or via a linker to the end of at least one of the sense strand and the antisense strand; and (iii) the polysaccharide and the single-stranded polydeoxyadenine form a complex.
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6.发明授权公开(公告)号：US09040492B2
公开(公告)日：2015-05-26
申请号：US12935546
申请日：2009-03-31
CPC分类号： C12N15/111 , C12N2310/3515 , C12N2320/32
摘要： An object of the present invention is to provide a novel double-stranded RNA that has high resistance to nuclease and cellular uptake efficiency and that can produce an excellent RNA interference effect. The present invention provides a double-stranded lipid-modified RNA comprising an antisense strand having a nucleotide sequence complementary to a target sequence in a target gene, and a sense strand having a nucleotide sequence complementary to the antisense strand, the double-stranded RNA being capable of suppressing the expression of the target gene, and the sense strand having a double-stranded lipid bound directly or via a linker to at least one of the first to sixth nucleotides from the 5′ end.
摘要翻译： 本发明的目的是提供对核酸酶和细胞摄取效率具有高抗性并且可以产生优异的RNA干扰效果的新型双链RNA。 本发明提供了包含具有与靶基因中的靶序列互补的核苷酸序列的反义链和具有与反义链互补的核苷酸序列的有义链的双链脂质修饰的RNA，所述双链RNA为 能够抑制靶基因的表达，并且将具有直链或经由连接基结合的双链脂质的有义链与5'末端的至少一个第一至第六个核苷酸结合。
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7.发明授权公开(公告)号：US08981074B2
公开(公告)日：2015-03-17
申请号：US12738797
申请日：2008-10-24
CPC分类号： A61K47/48038 , A61K47/542 , A61K47/543
摘要： An object of the present invention is to provide a novel double-stranded RNA that has high nuclease resistance and high cellular uptake efficiency, and that is capable of producing an excellent RNA interference effect. The present invention provides a lipid-modified double-stranded RNA comprising a sense strand having a nucleotide sequence complementary to a target sequence, and an antisense strand having a nucleotide sequence complementary to the sense strand, the double-stranded RNA being capable of inhibiting the expression of the target gene, the sense strand having a lipid linked to at least one of the first to sixth nucleotides from the 5′ end side directly or via a linker.
摘要翻译： 本发明的目的是提供具有高核酸酶抗性和高细胞摄取效率的新型双链RNA，并能够产生优异的RNA干扰效果。 本发明提供脂质修饰的双链RNA，其包含具有与靶序列互补的核苷酸序列的有义链和具有与有义链互补的核苷酸序列的反义链，所述双链RNA能够抑制 靶基因的表达，有义链具有从5'末端侧的至少一个第一至第六个核苷酸直接或通过连接体连接的脂质。
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公开(公告)号：US20110111501A1
公开(公告)日：2011-05-12
申请号：US12808504
申请日：2008-12-18
申请人： Takanori Kubo , Hideki Ohba , Kazuo Sakurai , Jusaku Minari , Atsushi Uno
发明人： Takanori Kubo , Hideki Ohba , Kazuo Sakurai , Jusaku Minari , Atsushi Uno
CPC分类号： C12N15/111 , C12N2310/14 , C12N2310/3519 , C12N2320/32 , C12N2320/51
摘要： An object of the present invention is to provide novel double-stranded RNA having an RNA interference effect, in which the cellular uptake and the resistance to enzymatic degradation are improved, without reducing the RNA interference effect.The cellular uptake and the resistance to enzymatic degradation of a complex of a polysaccharide having a β-1,3-glucan skeleton and double-stranded RNA can be significantly improved while maintaining the RNA interference effect, by fulfilling the following conditions (i) to (iii): (i) the double-stranded RNA has a sense strand consisting of a base sequence complementary to a target sequence in a target gene and an antisense strand containing a base sequence complementary to the sense strand, and the double-stranded RNA can inhibit expression of the target gene; (ii) the double-stranded RNA has a single-stranded polydeoxyadenine bound directly or via a linker to the end of at least one of the sense strand and the antisense strand; and (iii) the polysaccharide and the single-stranded polydeoxyadenine form a complex.
摘要翻译： 本发明的目的是提供具有RNA干扰效应的新颖的双链RNA，其中细胞摄取和对酶降解的抗性得到改善，而不降低RNA干扰效应。 通过满足以下条件，可以显着改善具有β-葡聚糖骨架和双链RNA的多糖的复合物的细胞摄取和抗降解，同时保持RNA干扰效应（i） 至（iii）：（i）双链RNA具有由与靶基因中的靶序列互补的碱基序列的有义链和含有与有义链互补的碱基序列的反义链，双链 RNA可抑制靶基因的表达; （ii）双链RNA具有单链多脱氧腺嘌呤，其直接或经由接头连接至至少一个有义链和反义链的末端; 和（iii）多糖和单链多脱氧腺嘌呤形成复合物。
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9.发明申请公开(公告)号：US20110034545A1
公开(公告)日：2011-02-10
申请号：US12935546
申请日：2009-03-31
IPC分类号： A61K31/713 , C07H21/02 , C12N5/071 , A61P35/00 , A61P31/18
CPC分类号： C12N15/111 , C12N2310/3515 , C12N2320/32
摘要： An object of the present invention is to provide a novel double-stranded RNA that has high resistance to nuclease and cellular uptake efficiency and that can produce an excellent RNA interference effect. The present invention provides a double-stranded lipid-modified RNA comprising a sense strand having a nucleotide sequence complementary to a target sequence in a target gene, and an antisense strand having a nucleotide sequence complementary to the sense strand, the double-stranded RNA being capable of suppressing the expression of the target gene, and the sense strand having a double-stranded lipid bound directly or via a linker to at least one of the first to sixth nucleotides from the 5′ end.
摘要翻译： 本发明的目的是提供对核酸酶和细胞摄取效率具有高抗性并且可以产生优异的RNA干扰效果的新型双链RNA。 本发明提供了包含具有与靶基因中的靶序列互补的核苷酸序列的有义链和具有与有义链互补的核苷酸序列的反义链的双链脂质修饰的RNA，所述双链RNA为 能够抑制靶基因的表达，并且将具有直链或经由连接基结合的双链脂质的有义链与5'末端的至少一个第一至第六个核苷酸结合。
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公开(公告)号：US06356173B1
公开(公告)日：2002-03-12
申请号：US09322739
申请日：1999-05-28
申请人： Koichi Nagata , Kenji Kitazawa , Shinichi Koriyama , Shigeki Morioka , Takanori Kubo , Hidehiro Minamiue , Masanobu Ishida , Akira Nakayama , Naoyuki Shino
发明人： Koichi Nagata , Kenji Kitazawa , Shinichi Koriyama , Shigeki Morioka , Takanori Kubo , Hidehiro Minamiue , Masanobu Ishida , Akira Nakayama , Naoyuki Shino
IPC分类号： H01P502
CPC分类号： H05K1/0239 , H01L23/66 , H01L2223/6627 , H01L2924/0002 , H01L2924/09701 , H01L2924/15192 , H01L2924/16152 , H01L2924/16153 , H01L2924/16251 , H01L2924/1903 , H01L2924/19107 , H01L2924/3011 , H05K1/0243 , H05K1/0272 , H05K1/0298 , H05K3/0061 , H05K2201/09054 , H01L2924/00
摘要： A high-frequency module in which a plurality of cavities are formed on the surface of a dielectric board, internal high-frequency signal transmission lines are connected to high-frequency devices in the cavities and are located in the cavities, the internal high-frequency signal transmission lines being electromagnetically coupled to the external high-frequency signal transmission line, and the high-frequency devices in the cavities are connected to each other relying on the electromagnetic coupling through the external line. The high-frequency module enables high-frequency signals to be transmitted among the high-frequency devices with a small loss. The module has a very simple structure, and is cheaply produced, and offers an advantage that it can be easily obtained in a small size.
摘要翻译： 一种高频模块，其中在介质板的表面上形成多个空腔，内部高频信号传输线连接到空腔中的高频器件，并且位于空腔中，内部高频 信号传输线被电磁耦合到外部高频信号传输线，并且空腔中的高频器件通过外部线路依赖于电磁耦合而相互连接。 高频模块使高频信号能够以较小的损耗在高频器件之间传输。 该模块具有非常简单的结构，并且便宜地生产，并且具有可以容易地以小尺寸获得的优点。
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