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公开(公告)号:US20240043823A1
公开(公告)日:2024-02-08
申请号:US18481086
申请日:2023-10-04
发明人: Jerod PTACIN , Carolina CAFFARO , Hans AERNI , Yorke ZHANG , Emil C. FISCHER , Aaron W. FELDMAN , Vivian T. DIEN , Floyd E. ROMESBERG
IPC分类号: C12N9/00 , C12P21/02 , C12N15/113 , C12N15/90
CPC分类号: C12N9/93 , C12P21/02 , C12Y601/01026 , C12N15/113 , C12N15/90
摘要: Disclosed herein are methods, compositions and kits for the synthesis of proteins which comprises unnatural amino acids that utilize a mutant tRNA.
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公开(公告)号:US20210222147A1
公开(公告)日:2021-07-22
申请号:US17196151
申请日:2021-03-09
发明人: Jerod PTACIN , Carolina CAFFARO , Hans AERNI , Yorke ZHANG , Emil C. FISCHER , Aaron W. FELDMAN , Vivian T. DIEN , Floyd E. ROMESBERG
IPC分类号: C12N9/00 , C12P21/02 , C12N15/113 , C12N15/90
摘要: Disclosed herein are methods, compositions and kits for the synthesis of proteins which comprises unnatural amino acids that utilize a mutant tRNA.
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公开(公告)号:US20220243244A1
公开(公告)日:2022-08-04
申请号:US17716848
申请日:2022-04-08
发明人: Floyd E. ROMESBERG , Emil C. FISCHER , Koji HASHIMOTO , Aaron W. FELDMAN , Vivian T. DIEN , Yorke ZHANG
IPC分类号: C12P21/02
摘要: Disclosed herein are compositions, methods, and kits for a cell incorporating unnatural amino acids into an unnatural polypeptide. Also disclosed herein are compositions, methods, and kits for increasing activity and yield of the unnatural polypeptide synthesized by the cell.
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