公开(公告)号：US20240307592A1

公开(公告)日：2024-09-19

申请号：US18034455

申请日：2021-10-29

申请人： Spiderwort Inc.

发明人： Ryan Hickey ,  Kama Szereszewski ,  Andrew E. Pelling ,  Paula Cristina de Sousa Faria Tischer ,  Anna CANTO ,  Joshua SALAMUN ,  Matthew LOURENCO

IPC分类号： A61L27/52 ,  A23L29/262 ,  A23L31/00 ,  A23P30/40 ,  A61L27/20 ,  A61L27/38 ,  A61L27/54 ,  A61L27/56 ,  C08L5/14

CPC分类号： A61L27/52 ,  A23L29/262 ,  A23L31/00 ,  A23P30/40 ,  A61L27/20 ,  A61L27/383 ,  A61L27/54 ,  A61L27/56 ,  C08L5/14 ,  A61L2300/402 ,  A61L2400/06 ,  A61L2430/02 ,  A61L2430/34 ,  A61L2430/38

摘要： Provided herein are aerogels and foams including: single structural cells and/or groups of structural cells derived from a plant or fungal tissue, the single structural cells having a decellularized 3D structure lacking cellular materials and nucleic acids of plant or fungal tissue; the single structural cells and/or groups of structural cells being distributed within a carrier derived from a dehydrated, lyophilized, or freeze-dried hydrogel. Also provided herein are methods for preparing aerogels or foams, including steps of: providing a decellularized plant or fungal tissue; obtaining single structural cells and/or groups of structural cells from the decellularized plant or fungal tissue by performing mercerization; mixing or distributing the single structural cells and/or groups of structural cells in a hydrogel, to provide a mixture; and dehydrating, lyophilizing, or freeze-drying the mixture to provide the aerogel or foam. Related methods and uses are also provided.

公开(公告)号：US20240336895A1

公开(公告)日：2024-10-10

申请号：US18293128

申请日：2022-07-29

申请人： Spiderwort Inc.

发明人： Andrew E. PELLING ,  Matthew LOURENCO ,  Ryan Hickey ,  Paula Cristina de Sousa Faria Tischer ,  Anna CANTO ,  Joshua SALAMUN ,  Colin RUSSELL

IPC分类号： C12N5/077 ,  A23J3/22 ,  A23L5/49 ,  A23L13/00 ,  A23L17/00 ,  A23L19/00 ,  C12N5/04

CPC分类号： C12N5/0658 ,  A23J3/227 ,  A23L5/49 ,  A23L13/00 ,  A23L17/00 ,  A23L19/09 ,  C12N5/04 ,  C12N2513/00 ,  C12N2533/70 ,  C12N2533/90 ,  C12N2537/10

摘要： Disclosed herein is a method of preparing a seeded biomaterial scaffold. The method comprises combining a biomaterial scaffold and a plurality of cells to provide a mixture; and applying a pressure to the mixture to thereby cause the plurality of cells to infiltrate the scaffold, thereby forming the seeded biomaterial scaffold.