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公开(公告)号：US20190285568A1
公开(公告)日：2019-09-19
申请号：US16434686
申请日：2019-06-07
发明人： Jennifer A. Samproni
IPC分类号： G01N27/327 , C25B9/18 , G01N33/487 , C12Q1/00
摘要： Fluid collection devices, analysis instruments and methods for making and using same are disclosed. The fluid collection device is provided with a device and an electrochemical cell. The device has first and second walls defining a microfluidic channel, and a sample application port communicating with the microfluidic channel. The first wall and the second wall are spaced a distance less than 150 microns. The electrochemical cell is disposed on the first wall to contact a sample travelling through the microfluidic channel. The electrochemical cell comprising molecule receptors such that a physical property of the first electrochemical cell is effected upon one or more of the molecule receptors binding to an electroactive species within the sample.
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公开(公告)号：US20180266972A1
公开(公告)日：2018-09-20
申请号：US15978659
申请日：2018-05-14
CPC分类号： G01N27/02 , A61M2205/3303 , G01N33/4915 , H05K1/189 , H05K2201/051 , H05K2201/055 , H05K2201/10151
摘要： A sensor assembly has a substrate with a first surface and a second surface opposite the first surface, at least one analyte sensor positioned on at least one of the first surface and the second surface of the substrate, and at least one electrical contact positioned on the substrate in electrical communication with a corresponding one of the at least one analyte sensor. The substrate is configured to define a tube having an interior surface, and an exterior surface. At least a portion of the first surface of the substrate defines the interior surface of the tube, and the at least one analyte sensor is disposed on at least one of the interior surface and the exterior surface of the tube.
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公开(公告)号：US20170203294A1
公开(公告)日：2017-07-20
申请号：US15324122
申请日：2015-07-09
发明人： Jennifer A. Samproni
IPC分类号： B01L3/00
摘要： In one aspect, the inventive concepts disclosed herein are directed to a sensor assembly which contains a first planar substrate and a second planar substrate which respectively support opposing sensor arrays and contains an integrated flow path extending between the first and second substrates. Sensor assembly contains a first planar substrate having a base layer, and a conductive layer formed on a first planar surface of the base layer. Base layer may be made from, for example, ceramic, polymer, foil, or any other type of material known to someone of ordinary skill in the art. Conductive layer contains at least at least two electrically isolated electrical contacts made, for example, using a thick film approach (e.g., screen printing, rotogravure, pad printing, stenciling conductive material such as carbon, Cu, Pt, Pd, Au, and/or Nanotubes, etc.) or a thin firm approach (e.g., by sputtering, thermal spraying, and/or cold spraying conductive material).
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公开(公告)号：US11408882B2
公开(公告)日：2022-08-09
申请号：US16987921
申请日：2020-08-07
发明人： Jennifer A. Samproni , Todd Andrade , Marlene Shi
摘要： In the various illustrative embodiments herein, test devices are described with opposing sensor arrays and same side contacts.
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公开(公告)号：US20170184532A1
公开(公告)日：2017-06-29
申请号：US15325307
申请日：2015-07-17
发明人： Jennifer A. Samproni
IPC分类号： G01N27/27
CPC分类号： G01N27/27 , G01N27/3272
摘要： In one illustrative embodiment, a test strip with a first planar substrate has coplanar electrodes on a first planar surface and a second planar substrate (which opposes the first surface of the first planar substrate) has coplanar electrodes on a second planar surface. The first planar surface of the first planar substrate having a first sensing area electrically connected to a first electrical contact. The second planar surface of the second planar substrate having a second electrical contact electrically connected to the first electrical contact via a conductive element, the conductive element extending between the first surface of the first planar substrate and the second surface of the second planar substrate without passing through the first planar substrate, the second planar substrate, or any intermediate layers.
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6.发明授权Devices containing dried reagents for reconstitution as calibration and/or quality control solutions, and methods of production and use thereof 有权含有用于重构的干燥试剂作为校准和/或质量控制溶液的装置及其生产和使用方法公开(公告)号：US09244085B2
公开(公告)日：2016-01-26
申请号：US14359799
申请日：2012-11-19
发明人： Jennifer A. Samproni
CPC分类号： G01N33/96 , C12N9/00 , C12N9/96 , C12Q1/26 , C12Q1/485 , C12Q1/54 , Y10T436/102499 , Y10T436/204998 , Y10T436/207497 , Y10T436/2525 , Y10T436/2575
摘要： Devices contain dried reagents that may be reconstituted and used in the calibration and quality control of sensors. Methods of producing and using the devices are also disclosed.
摘要翻译： 设备含有干燥的试剂，可以重新配制并用于传感器的校准和质量控制。 还公开了制造和使用装置的方法。
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公开(公告)号：US20150176143A1
公开(公告)日：2015-06-25
申请号：US14409771
申请日：2013-06-27
发明人： Jennifer A. Samproni
IPC分类号： C25B9/18
CPC分类号： G01N27/3277 , C12Q1/004 , C25B9/18 , G01N27/3272 , G01N33/48707 , G01N33/4915 , G01N33/492 , Y10T29/49117
摘要： Fluid collection devices, analysis instruments and methods for making and using same are disclosed. The fluid collection device is provided with a device and an electrochemical cell. The device has first and second walls defining a microfluidic channel, and a sample application port communicating with the microfluidic channel. The first wall and the second wall are spaced a distance less than 150 microns. The electrochemical cell is disposed on the first wall to contact a sample travelling through the micro-fluidic channel. The electrochemical cell comprising molecule receptors such that a physical property of the first electrochemical cell is effected upon one or more of the molecule receptors binding to an electroactive species within the sample.
摘要翻译： 公开了用于制造和使用它们的流体收集装置，分析仪器和方法。 流体收集装置设置有装置和电化学电池。 该装置具有限定微流体通道的第一壁和第二壁以及与微流体通道连通的样品施加口。 第一壁和第二壁的距离小于150微米。 电化学电池设置在第一壁上以接触穿过微流体通道的样品。 包含分子受体的电化学电池使得第一电化学电池的物理性能受到结合于样品中的电活性物质的一种或多种分子受体的影响。
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公开(公告)号：US11382185B2
公开(公告)日：2022-07-05
申请号：US16067698
申请日：2017-01-06
发明人： Jennifer A. Samproni
IPC分类号： H05B6/62 , H05B3/26 , G01N27/327 , G01N33/487
摘要： In the various illustrative embodiments herein, test devices are described with opposing sensor arrays, same side contacts, and an integrated heating element.
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公开(公告)号：US10814322B2
公开(公告)日：2020-10-27
申请号：US15324122
申请日：2015-07-09
发明人： Jennifer A. Samproni
IPC分类号： B01L3/00 , G01N33/487
摘要： In one aspect, the inventive concepts disclosed herein are directed to a sensor assembly which contains a first planar substrate and a second planar substrate which respectively support opposing sensor arrays and contains an integrated flow path extending between the first and second substrates. Sensor assembly contains a first planar substrate having a base layer, and a conductive layer formed on a first planar surface of the base layer. Base layer may be made from, for example, ceramic, polymer, foil, or any other type of material known to someone of ordinary skill in the art. Conductive layer contains at least at least two electrically isolated electrical contacts made, for example, using a thick film approach (e.g., screen printing, rotogravure, pad printing, stenciling conductive material such as carbon, Cu, Pt, Pd, Au, and/or Nanotubes, etc.) or a thin firm approach (e.g., by sputtering, thermal spraying, and/or cold spraying conductive material).
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公开(公告)号：US09945804B2
公开(公告)日：2018-04-17
申请号：US15325307
申请日：2015-07-17
发明人： Jennifer A. Samproni
IPC分类号： G01N27/403 , G01N27/327 , G01N27/27
CPC分类号： G01N27/27 , G01N27/3272
摘要： In one illustrative embodiment, a test strip with a first planar substrate has coplanar electrodes on a first planar surface and a second planar substrate (which opposes the first surface of the first planar substrate) has coplanar electrodes on a second planar surface. The first planar surface of the first planar substrate having a first sensing area electrically connected to a first electrical contact. The second planar surface of the second planar substrate having a second electrical contact electrically connected to the first electrical contact via a conductive element, the conductive element extending between the first surface of the first planar substrate and the second surface of the second planar substrate without passing through the first planar substrate, the second planar substrate, or any intermediate layers.
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