Abstract:
A cell capturing filter, in which cells or particles having a predetermined size or greater in a sample may be easily captured, and clogging of a flow passage due to the captured cells or particles may be prevented, and stresses acting on the captured cells or particles may be reduced, having a first surface and a second substrate having a second surface that is bonded to the first surface, wherein the first substrate may include a flow passage formed in the first surface of the first substrate so that a sample flows in the flow passage, and a barrier that protrudes across the flow passage, and the second substrate may include a fine groove formed in an area on the second surface corresponding to the barrier, and a gap may exist between a surface of the barrier and the fine groove.
Abstract:
A target material capturing filter is described herein. The target material capturing filter may include an inlet through which a fluid enters; an outlet through which at least a portion of the fluid is discharged; a first flow path that is connected to the inlet; a second flow path that is connected to the outlet; and a filter unit that is disposed between the first flow path and the second flow path and captures the target material by letting drop at least a portion of the fluid that flows through the first flow path.
Abstract:
Provided is a composition and a kit for separating a cancer stem cell or a circulating tumor cell, a method of separating a cancer stem cell or a circulating tumor cell in a biological sample, and a method for diagnosing metastatic cancer.
Abstract:
A method of re-collecting a target material using a filter is provided. The method includes reversely flowing a first fluid from a first flow channel towards a second flow channel through a filter unit so that the target material is included in the first fluid that flows through the second flow channel, wherein the filter includes: the first flow channel, the second flow channel that at least in part overlaps the first flow channel and is disposed above the first flow channel, and the filter unit that is disposed on a region where the first flow channel overlaps the second flow channel and where the target material is captured.
Abstract:
Provided are compositions, kits, and methods for separating cells including complexes of at least one type of linker capable of binding to an antibody or antigen binding fragment and a solid phase.
Abstract:
Provided herein is a method of sequential and multiple immunostaining for detection of various antigens in the same specimens, which may be used for qualitative or quantitative analysis of proteins expressed, gene analysis, and morphological analysis even in specimens where only a small amount is available.
Abstract:
A polypeptide linker comprising an antibody-binding region and an enzyme cleavage region, and related compositions, kits, and methods of using same.