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    Compounds and Mixtures Influencing Inflammatory States
    3.
    发明申请
    Compounds and Mixtures Influencing Inflammatory States 审中-公开
    影响炎症状态的化合物和混合物

    公开(公告)号：US20130251730A1

    公开(公告)日：2013-09-26

    申请号：US13782391

    申请日：2013-03-01

    Applicant: SYMRISE AG

    Inventor： Jakob Ley ,  Katharina Reichelt ,  Marcus Götz ,  Maria Blings ,  Veronika Somoza ,  Jessica Walker ,  Joel Michael Walker

    IPC: A61K31/192 ,  C07D311/58 ,  A23L1/30 ,  C07D311/32 ,  A61K45/06 ,  C07C65/40 ,  A61K31/353

    CPC classification number: A61K31/192 ,  A23L33/105 ,  A61K8/365 ,  A61K8/498 ,  A61K31/352 ,  A61K31/353 ,  A61K45/06 ,  A61K2800/10 ,  A61Q19/00 ,  C07C65/40 ,  C07D311/32 ,  C07D311/58 ,  A61K2300/00

    Abstract: Suggested is a compound of the formula (X) or any salt of a compound of the formula (X) or any mixture containing or consisting of two or more different compounds of the formula (X), two or more different salts of compounds of the formula (X) or one or more different compounds of the formula (X) and one or more different salts of compounds of the formula (X), wherein for R1, R2 and R3 independently of one another in every compound of the formula (X) the following applies: R1 means hydrogen or methyl, R2 means an organic residue with 5 carbon atoms and one oxygen atom or none and R3 means an organic residue with 10 carbon atoms and one or more oxygen atoms, or R1 and R2 together with the carbon atoms in positions 4 and 5 and the oxygen atom bound to the carbon atom in position 4 form a ring and comprise 5 carbon atoms and one oxygen atom or none, and R3 means an organic residue with 10 carbon atoms and one or more oxygen atoms, for use in a method for the prophylaxis and/or treatment of inflammation.

    Abstract translation: 建议式（X）的化合物或式（X）化合物的任何盐或含有两种或更多种不同式（X）化合物的任何混合物或两种或更多种不同的 式（X）或一种或多种不同的式（X）化合物和一种或多种式（X）化合物的不同盐，其中对于R 1，R 2和R 3在每个式（X ）适用：R 1表示氢或甲基，R 2表示具有5个碳原子和一个氧原子的有机残基或不表示R 3表示具有10个碳原子和一个或多个氧原子的有机残基，或R 1和R 2与 位置4和5中的碳原子和结合到位置4的碳原子的氧原子形成环，并且包含5个碳原子和一个氧原子或不存在，并且R 3表示具有10个碳原子和一个或多个氧原子的有机残基 ，用于预防和/或治疗的方法 炎症。

    Oral compositions
    4.
    发明授权
    Oral compositions 有权
    口服成分

    公开(公告)号：US09468225B2

    公开(公告)日：2016-10-18

    申请号：US14179170

    申请日：2014-02-12

    Applicant: Symrise AG

    Inventor： Jakob Ley ,  Sabine Widder ,  Veronika Somoza ,  Barbara Rohm ,  Matthias Zaunschirm ,  Gerhard Krammer

    IPC: A61K31/16 ,  A61K31/164 ,  A23K20/105 ,  A23K1/16 ,  A23L1/29 ,  A23L1/30

    CPC classification number: A23K20/105 ,  A23L33/10 ,  A23L33/30 ,  A61K31/16 ,  A61K31/164

    Abstract: Suggested are new compositions for oral ingestion, comprising at least one active agent from the group of alkamides. The compositions which are orally ingested reduce the uptake of free fatty acids in the adipocytes and at the same time stimulate the release of serotonin and dopamine, which leads to a reduction of appetite, a feeling of satiety and a positive mood. In doing so, the new compositions are thus perfectly suitable to counteract any undesired gain of weight.

    Abstract translation: 建议的是用于口服摄取的新组合物，其包含至少一种来自该组烷酰胺的活性剂。 口服摄入的组合物降低脂肪细胞中游离脂肪酸的摄取量，同时刺激5-羟色胺和多巴胺的释放，这导致食欲降低，饱腹感和积极情绪。 因此，新组合物非常适合抵消任何不希望的重量增益。

    COMBINATION REMEDY
    5.
    发明申请
    COMBINATION REMEDY 有权

    公开(公告)号：US20220071933A1

    公开(公告)日：2022-03-10

    申请号：US17423400

    申请日：2019-01-18

    Applicant: SYMRISE AG

    Inventor： Jakob Ley ,  Veronika Somoza ,  Verena Stöger ,  Joachim Hans

    IPC: A61K31/165 ,  A61K31/198 ,  A61K38/01 ,  A61K45/06 ,  A23L33/18 ,  A23L33/175

    Abstract: The present invention primarily relates to a combination agent for reducing appetite and/or for providing a feeling of satiety and/or for reducing energy intake and/or for reducing body weight. In addition, the present invention relates to a medical use of the combination agent, in particular for the treatment of overweight and obesity and for the prevention of cardiovascular disease, stroke, diabetes, and joint damage and wear of the spine, and to a non-therapeutic use of the combination agent. In particular, the focus of the present invention is on the use of the combination agent to provide a feeling of satiety and/or to reduce energy intake and/or to reduce body weight. Finally, the present invention relates to the use of the combination agent for the preparation of an orally consumable preparation or food ingredient and an orally consumable preparation or food ingredient prepared therefrom.

    ORAL COMPOSITIONS
    10.
    发明申请
    ORAL COMPOSITIONS 有权
    口腔组成

    公开(公告)号：US20140234412A1

    公开(公告)日：2014-08-21

    申请号：US14179170

    申请日：2014-02-12

    Applicant: Symrise AG

    Inventor： Jakob Ley ,  Sabine Widder ,  Veronika Somoza ,  Barbara Rohm ,  Matthias Zaunschirm ,  Gerhard Krammer

    IPC: A61K31/16 ,  A23K1/16 ,  A23L1/30

    CPC classification number: A23K20/105 ,  A23L33/10 ,  A23L33/30 ,  A61K31/16 ,  A61K31/164

    Abstract: Suggested are new compositions for oral ingestion, comprising at least one active agent from the group of alkamides. The compositions which are orally ingested reduce the uptake of free fatty acids in the adipocytes and at the same time stimulate the release of serotonin and dopamine, which leads to a reduction of appetite, a feeling of satiety and a positive mood. In doing so, the new compositions are thus perfectly suitable to counteract any undesired gain of weight.

    Abstract translation: 建议的是用于口服摄取的新组合物，其包含至少一种来自该组烷酰胺的活性剂。 口服摄入的组合物降低脂肪细胞中游离脂肪酸的摄取量，同时刺激5-羟色胺和多巴胺的释放，这导致食欲降低，饱腹感和积极情绪。 因此，新组合物非常适合抵消任何不希望的重量增加。

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