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公开(公告)号：US10806904B2
公开(公告)日：2020-10-20
申请号：US15467554
申请日：2017-03-23
Applicant: Surmodics, Inc.
Inventor： Bruce M. Jelle , Joram Slager , Joseph Schmidt McGonigle , Nathan A. Lockwood
Abstract: Embodiments herein include an insertion tool for inserting a medical device into another medical device, such as a hemostasis sealing valve, and related methods. In an embodiment, an insertion tool includes a guide sheath and a protection tube. The guide sheath can include a flared proximal end. The guide sheath can further include a central lumen. The guide sheath can further include a locking notch disposed on the inner surface between the proximal end and the distal end. The protection tube can include a flared proximal end. A portion of the protection tube can be situated within the central lumen of the guide sheath. The flared proximal end of the protection tube can be sized to fit within the locking notch and can have an outer diameter larger than portions of the inner surface immediately adjacent to the locking notch. Other embodiments are also included herein.
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2.发明申请CONDUCTIVE POLYMERIC COATINGS, MEDICAL DEVICES, COATING SOLUTIONS AND METHODS 审中-公开导电聚合物涂层，医疗器械，涂层解决方案和方法公开(公告)号：US20160208114A1
公开(公告)日：2016-07-21
申请号：US14914586
申请日：2014-08-25
Applicant: Jeffrey L. HENDRICKS , Sarah M. RICHARDSON-BURNS , Kyle MALLIRES , Sarah A. SPANNINGA , SURMODICS, INC.
Inventor： Jeffrey L. Hendricks , Sarah M. Richardson-Burns , Kyle Mallires , Sarah A. Spanninga , Nathan A. Lockwood , Robert W. Hergenrother , Bruce M. Jelle
Abstract: The invention includes conductive polymeric coatings, medical device, coating solutions and methods of making the same. A coating solution for forming a conductive polymer layer can include a conductive monomer, at least one photoreactive component comprising an anionic photoreactive cross-linking agent or an anionic photoreactive hydrophilic polymer, and a solvent. A medical device can include an electrode and an electrically conductive coating disposed over the electrode. The electrically conductive coating can include a reaction product of the conductive monomer and the at least one photoreactive component. Other aspects are included herein.
Abstract translation: 本发明包括导电聚合物涂层，医疗装置，涂层溶液及其制备方法。 用于形成导电聚合物层的涂布溶液可以包括导电单体，至少一种包含阴离子光反应性交联剂或阴离子光反应性亲水性聚合物的光反应性组分和溶剂。 医疗装置可以包括设置在电极上的电极和导电涂层。 导电涂层可以包括导电单体和至少一种光反应组分的反应产物。 本文还包括其他方面。
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3.发明申请STILBENE-BASED REACTIVE COMPOUNDS, POLYMERIC MATRICES FORMED THEREFROM, AND ARTICLES VISUALIZABLE BY FLUORESCENCE 有权基于STILBENE的反应性化合物，其形成的聚合物和可透过荧光的物质公开(公告)号：US20140162083A1
公开(公告)日：2014-06-12
申请号：US14104208
申请日：2013-12-12
Applicant: SurModics, Inc.
Inventor： Aleksey V. Kurdyumov , Dale G. Swan , Nathan A. Lockwood , Bruce M. Jelle
IPC: A61L31/14 , C07C233/81 , A61L31/10 , C07D251/68
CPC classification number: A61L31/14 , A61B1/00135 , A61B1/005 , A61L31/10 , C07C235/84 , C07C309/46 , C07D251/54 , C07D251/68 , Y10T428/31942
Abstract: The invention is directed to latent reactive and polymerizable derivatives of fluorescent stilbene-based compounds. The compounds can be used to provide articles with a fluorescence property, such as medical devices (e.g., catheters). The fluorescent compounds can be used in association with polymers, or can be incorporated into polymers, and the polymers used in a coating composition on the article surface. The compounds allow for visual or machine inspection of coating properties such as uniformity of coverage.
Abstract translation: 本发明涉及荧光芪类化合物的潜在反应性和可聚合衍生物。 这些化合物可用于提供具有荧光性质的制品，例如医疗装置（例如导管）。 荧光化合物可以与聚合物结合使用，或者可以并入聚合物中，以及用于制品表面上的涂料组合物中的聚合物。 这些化合物允许对涂层性能进行视觉或机器检查，例如覆盖的均匀性。
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公开(公告)号：US10695174B2
公开(公告)日：2020-06-30
申请号：US15543704
申请日：2016-01-14
Applicant: SURMODICS, INC.
Inventor： Bruce M. Jelle , Joram Slager , Joseph S. McGonigle , Rick Murphy , Andrew G. Bach , Teryl L. Woodwick Sides , Ambereen Angamuthu , Sean Lundquist , Gary Opperman , Nathan A. Lockwood
Abstract: The disclosure provides insertion tools and articles that facilitate entry of a medical device, such as a balloon catheter, into the body. In embodiments the insertion tools have an elongate hollow body (50) that is able to protect a portion of a medical device, such as a balloon of a balloon catheter, during an insertion procedure. In one embodiment the insertion tool has an elongate hollow body (131), a tapered distal end (135), and a locking mechanism (133) at the proximal end which can secure a portion of a balloon catheter. An opening at the distal end can allow passage of the balloon in a folded uninflated state.
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5.发明授权Hydrophilic polymeric coatings for medical articles with visualization moiety 有权具有可视化部分的医疗用品的亲水性聚合物涂层公开(公告)号：US08956682B2
公开(公告)日：2015-02-17
申请号：US13855260
申请日：2013-04-02
Applicant: SurModics, Inc.
Inventor： Nathan A. Lockwood , Bruce M. Jelle , Aleksey V. Kurdyumov
IPC: A61L33/00 , A61F2/00 , A61K9/14 , B05B5/00 , A01N35/00 , A61K31/12 , C09D5/22 , C09D5/00 , B05D3/06 , A61L29/08 , A61L29/14 , A61L29/18
CPC classification number: C09D5/22 , A61L29/085 , A61L29/14 , A61L29/18 , A61L2420/02 , B05D3/067 , C09D5/00 , Y10T428/31725 , Y10T428/31938 , C08L39/06
Abstract: The invention is directed to medical device coatings, such as coated guidewires and catheters, containing a visualization moiety providing color to the coating in ambient or applied light. The coating allows for visual or machine inspection of coating properties such as uniformity of coverage. In some embodiments the coatings include the visualization moiety and an activated UV photogroup, which is used to provide covalent bonding in the coating. The visualization moiety can be in particulate form and entrained in the coating, or can be covalently bonded to the hydrophilic polymer backbone. In other embodiments the visualization moiety includes a stilbene chemical group. Exemplary coatings include a hydrophilic vinyl pyrrolidone polymer, which can provide lubricity to the device surface, along with the colored properties.
Abstract translation: 本发明涉及医疗器械涂层，例如涂覆的导线和导管，其包含在环境或应用光下为涂层提供颜色的可视化部分。 涂层允许对涂层性能进行视觉或机器检查，例如覆盖的均匀性。 在一些实施方案中，涂层包括可视化部分和活化的UV光电子组，其用于在涂层中提供共价键合。 可视化部分可以是颗粒形式并夹带在涂层中，或者可以共价键合到亲水性聚合物主链上。 在其它实施方案中，可视化部分包括茋化学基团。 示例性涂层包括亲水性乙烯基吡咯烷酮聚合物，其可以提供对器件表面的润滑性以及着色性质。
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Patent Agency Ranking
公开(公告)号：US20140200411A1
公开(公告)日：2014-07-17
申请号：US14152667
申请日：2014-01-10
Applicant: SurModics, Inc.
Inventor： Bruce M. Jelle , Aleksey V. Kurdyumov , Joseph Schmidt McGonigle , Robert W. Hergenrother , Nathan A. Lockwood , Joseph Ventura , Sean M. Stucke
CPC classification number: A61L31/10 , A61B2562/125 , A61L31/14 , A61N1/0404 , A61N1/05 , C07D495/04 , C07D519/00 , C08G61/02 , C08G61/124 , C08G61/126 , C08G73/0266 , C08G2261/1424 , C08G2261/1426 , C08G2261/1428 , C08G2261/143 , C08G2261/144 , C08G2261/145 , C08G2261/148 , C08G2261/3221 , C08G2261/3223 , C08G2261/3422 , C08G2261/43 , C08G2261/76 , C08G2261/77 , C08G2261/90 , C08G2261/94 , C09D5/24 , H01B1/127 , Y10T428/31507 , Y10T428/31533
Abstract: Disclosed herein are activatable conductive compositions and methods of making and using activatable conductive compositions. In particular, activatable conductive monomers polymers are described and electrically conductive coatings that include activatable conductive polymers.
Abstract translation: 本文公开了可激活的导电组合物和制备和使用可活化导电组合物的方法。 特别地，描述了可激活的导电单体聚合物和包括可激活的导电聚合物的导电涂层。
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7.发明申请公开(公告)号：US20130261566A1
公开(公告)日：2013-10-03
申请号：US13855260
申请日：2013-04-02
Applicant: SURMODICS, INC.
Inventor： Nathan A. Lockwood , Bruce M. Jelle , Aleksey V. Kurdyumov
CPC classification number: C09D5/22 , A61L29/085 , A61L29/14 , A61L29/18 , A61L2420/02 , B05D3/067 , C09D5/00 , Y10T428/31725 , Y10T428/31938 , C08L39/06
Abstract: The invention is directed to medical device coatings, such as coated guidewires and catheters, containing a visualization moiety providing color to the coating in ambient or applied light. The coating allows for visual or machine inspection of coating properties such as uniformity of coverage. In some embodiments the coatings include the visualization moiety and an activated UV photogroup, which is used to provide covalent bonding in the coating. The visualization moiety can be in particulate form and entrained in the coating, or can be covalently bonded to the hydrophilic polymer backbone. In other embodiments the visualization moiety includes a stilbene chemical group. Exemplary coatings include a hydrophilic vinyl pyrrolidone polymer, which can provide lubricity to the device surface, along with the colored properties.
Abstract translation: 本发明涉及医疗器械涂层，例如涂覆的导线和导管，其包含在环境或应用光下为涂层提供颜色的可视化部分。 涂层允许对涂层性能进行视觉或机器检查，例如覆盖的均匀性。 在一些实施方案中，涂层包括可视化部分和活化的UV光电子组，其用于在涂层中提供共价键合。 可视化部分可以是颗粒形式并夹带在涂层中，或者可以共价键合到亲水性聚合物主链上。 在其它实施方案中，可视化部分包括茋化学基团。 示例性涂层包括亲水性乙烯基吡咯烷酮聚合物，其可以提供对器件表面的润滑性以及着色性质。
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公开(公告)号：US11576774B2
公开(公告)日：2023-02-14
申请号：US16914950
申请日：2020-06-29
Applicant: Surmodics, Inc.
Inventor： Bruce M. Jelle , Joram Slager , Joseph S. McGonigle , Rick Murphy , Andrew G. Bach , Teryl L. Woodwick Sides , Ambereen Angamuthu , Sean Lundquist , Gary Opperman , Nathan A. Lockwood
Abstract: The disclosure provides insertion tools and articles that facilitate entry of a medical device, such as a balloon catheter, into the body. In embodiments the insertion tools have an elongate hollow body (50) that is able to protect a portion of a medical device, such as a balloon of a balloon catheter, during an insertion procedure. In one embodiment the insertion tool has an elongate hollow body (131), a tapered distal end (135), and a locking mechanism (133) at the proximal end which can secure a portion of a balloon catheter. An opening at the distal end can allow passage of the balloon in a folded uninflated state.
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公开(公告)号：US20210015613A1
公开(公告)日：2021-01-21
申请号：US16914950
申请日：2020-06-29
Applicant: Surmodics, Inc.
Inventor： Bruce M. Jelle , Joram Slager , Joseph S. McGonigle , Rick Murphy , Andrew G. Bach , Teryl L. Woodwick Sides , Ambereen Angamuthu , Sean Lundquist , Gary Opperman , Nathan A. Lockwood
Abstract: The disclosure provides insertion tools and articles that facilitate entry of a medical device, such as a balloon catheter, into the body. In embodiments the insertion tools have an elongate hollow body (50) that is able to protect a portion of a medical device, such as a balloon of a balloon catheter, during an insertion procedure. In one embodiment the insertion tool has an elongate hollow body (131), a tapered distal end (135), and a locking mechanism (133) at the proximal end which can secure a portion of a balloon catheter. An opening at the distal end can allow passage of the balloon in a folded uninflated state.
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公开(公告)号：US20170367824A1
公开(公告)日：2017-12-28
申请号：US15543704
申请日：2016-01-14
Applicant: SURMODICS, INC.
Inventor： Bruce M. Jelle , Joram Slager , Joseph S. McGonigle , Rick Murphy , Andrew G. Bach , Teryl L. Woodwick Sides , Ambereen Angamuthu , Sean Lundquist , Gary Opperman , Nathan A. Lockwood
CPC classification number: A61F2/2433 , A61M25/0102 , A61M25/0668 , A61M25/09041 , A61M25/10 , A61M2025/0681 , A61M2025/1081
Abstract: The disclosure provides insertion tools and articles that facilitate entry of a medical device, such as a balloon catheter, into the body. In embodiments the insertion tools have an elongate hollow body (50) that is able to protect a portion of a medical device, such as a balloon of a balloon catheter, during an insertion procedure. In one embodiment the insertion tool has an elongate hollow body (131), a tapered distal end (135), and a locking mechanism (133) at the proximal end which can secure a portion of a balloon catheter. An opening at the distal end can allow passage of the balloon in a folded uninflated state.
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